W.M. Keck Biotechnology Resource Laboratory

The Keck Biotechnology Resource Laboratory provides >135 genomic, proteomic, biostatistical, and high performance computing technologies to hundreds of Yale and non-Yale investigators whose research otherwise might not benefit from the highly sophisticated and expensive instrumentation upon which biological and biomedical research is increasingly dependent.  With 40 staff, including 15 with Ph.D. and 7 with M.S. level degrees, >26,000 ft² of custom-designed space, and >110 major instrument systems purchased at a cost of >$12 million dollars; we believe the Keck Lab is among the largest academic biotechnology resource laboratories of its kind. The Keck Biotechnology Resource Laboratory operates on a fee-for service basis and also houses cores for several NIH Centers.

The Keck Biotechnology Resource Laboratory is organized into 3 genomic (DNA Sequencing, Microarray, and Oligo Synthesis), 7 proteomic (Amino Acid Analysis, Biophysics, MS/Proteomics, Protein Microarray, Protein Sequencing, Small Scale and Large Scale Peptide Synthesis), and 3 multi-disciplinary Resources (Bioinformatics, Biostatistics, and High Performance Computing).  The 13 Keck Resources provide a wide range of syntheses and analyses that include gene expression and SNP genotyping using microarray and bead technologies, oligo and peptide synthesis, DNA and protein sequencing, biophysical analysis of proteins and other biopolymers, biostatistical analyses, mass spectrometry (MS), protein profiling, and high performance computing.