W.M. Keck Biotechnology Resource Laboratory
***The Keck Biotechnology Resource Laboratory is no longer offering Amino Acid Analysis (AAA), N-terminal Sequencing (Edman Degradation), and Large-and Small-Scale Peptide Synthesis services. We continue to provide a large number of genomic and proteomic services. A comprehensive list of these services is available via the links above.
The Keck Biotechnology Resource Laboratory provides ~113 genomic, proteomic, biostatistical, bioinformatics, and high performance computing technologies to hundreds of Yale and non-Yale investigators whose research otherwise might not benefit from the highly sophisticated and expensive instrumentation upon which biological and biomedical research is increasingly dependent. In fiscal year 2013 the Keck Lab carried out 334,252 analyses and syntheses for 441 Yale and 589 non-Yale investigators at 272 institutions in 31 countries. With 38 staff, including 18 with Ph.D. and 5 with M.S. level degrees, ~22,000 ft2 of custom-designed space, and ~133 major instrument systems purchased at a cost of ~$12 million dollars; we believe the Keck Lab is among the largest academic biotechnology resource laboratories of its kind. The Keck Biotechnology Resource Laboratory operates on a fee-for service basis and also houses cores for several NIH Centers.
The Keck Biotechnology Resource Laboratory is organized into three genomic (DNA Sequencing, Microarray, and Oligo Synthesis), two proteomic (Biophysics and MS/Proteomics), and three multi-disciplinary Resources (Bioinformatics, Biostatistics, and High Performance Computing). The 8 Keck Resources provide a wide range of syntheses and analyses that include gene expression and SNP genotyping using microarray technologies, oligo synthesis, DNA sequencing, biophysical analysis of proteins and other biopolymers, biostatistical and bioinformatics analyses, mass spectrometry (MS), protein profiling, and high performance computing.