Research

The Yale Program on Aging/Yale Pepper Center

The Yale Program on Aging/Yale Pepper Center (POA/Pepper Center) is an inter-departmental, multidisciplinary center whose objectives are to investigate clinical, translational and epidemiologic topics related to the multi factorial issues of aging. It is supported through the National Institute on Aging.

The POA/Pepper Center provides support to numerous aging related projects at Yale and other institutions including those described below. Please click on Pepper in the banner headings to find out more about the Center.

Hartford Foundation Center of Excellence in Aging

The overarching objective of the Yale Hartford Center of Excellence (CoE) is to increase the quantity and quality of faculty who are able to teach, conduct research, and provide leadership for aging and geriatric issues.  To accomplish this objective, the aim of the Yale/Hartford COE in Aging is to provide research training, support, and mentorship to geriatrically-trained fellows and junior faculty. The Yale CoE supports both research and educational scholars.  While our priority is developing geriatrically-trained faculty, we also support highly qualified physician investigators conducting age-related research in the medical subspecialties.

Center on Disability and Disabling Disorders

The objective of the Yale Center on Disability and Disabling Disorders is to address fundamental issues related to the epidemiology and prevention of disability, a problem of immense importance to older persons, their families and society. Under the leadership of Dr. Thomas Gill (Director) and Dr. Nathalie de Rekeneire (Deputy Director), the Center conducts longitudinal studies and clinical trials to enhance the scientific knowledge base of the disablement process and to rigorously evaluate promising intervention strategies. The Center includes clinical investigators and trainees across disciplines, who are pursuing aging research related to disability and disabling disorders. This includes functional assessment in general as well as the functional consequences of highly prevalent disease-specific conditions such as arthritis, heart failure, chronic obstructive pulmonary disease, diabetes, stroke, depression, and dementia. Other faculty members include Dr. Sarwat Chaudhry (Heart Failure), Dr. Carlos Vaz Fragoso (Sleep and Pulmonary Function), and Dr. Heather Allore (Study Design and Biostatistics).  Among the ongoing studies are the Precipitating Events Project (PEP Study), the T (Testosterone) Trial, and the Lifestyle Interventions and Independence for Elders (LIFE) Study. The Center works closely with the superb Resource Cores of the Program on Aging (Field, Biostatistics, and Informatics) and has access to data from several large NIH-sponsored studies, including the Health ABC Study, Cardiovascular Health Study, MrOS, National Social Life, Health and Aging Project (NSHAP), and LIFE-P Study, and from the UK's Medical Resource Council National Survey of Health and Development (NSHD).  Ample research and training opportunities are available to fellows, residents, and students, including formal postdoctoral training;in Geriatric Clinical Epidemiology and Aging-Related Research, sponsored by the National Institute on Aging.

Dissemination Projects

Connecticut Collaboration for Fall Prevention. The objective of the Collaboration is to implement, within the greater Hartford area, a multifaceted, multidisciplinary fall prevention program that reaches older adults via the existing health care system and community organizations. The fall prevention interventions are based on a randomized clinical trial conducted at Yale which found that a multifactorial intervention strategy resulted in a 36% reduction in the fall rate among community living older adults.

Biology of Aging Basic Science Research Program

This series includes fellows, trainees, and junior and senior faculty from multiple disciplines and departments engaged in basic science research, including animal studies, with a focus on aging. Please contact Dr. Al Shaw or Eliza Kiwak to be included on the mailing list. This series offers a forum for:

  • Junior faculty to present in progress or completed studies and receive feedback from senior faculty senior investigators and outside investigators to present their work
  • Bring together researchers from multiple disciplines and encourage collaborative relationships

Seminars are held monthly and attendance is about 15 people per seminar.