Pepper Center Publications

Zhang H, Wang F, Xu H, Liu Y, Liu J, Zhao H and Gelernter J: Differentially co-expressed genes in postmortem prefrontal cortex of individuals with alcohol use disorders: influence on alcohol metabolism-related pathways. Hum Genet. 2014 Nov;133 (11) :1383-94. Epub 2014 Jul 30. PMID: 25073604


Juthani-Mehta M, Datunashvili A and Tinetti M: Tests for urinary tract infection in nursing home residents. JAMA. 2014 Oct 22-29;312 (16) :1687-8. PMID: 25335152


Hou L, Ma T and Zhao H: Incorporating functional annotation information in prioritizing disease associated SNPs from genome wide association studies. Sci China Life Sci. 2014 Oct 17; Epub 2014 Oct 17. PMID: 25326070


Ahasic AM, Van Ness PH, Murphy TE, Araujo KL and Pisani MA: Functional status after critical illness: agreement between patient and proxy assessments. Age Ageing. 2014 Oct 16; Epub 2014 Oct 16. PMID: 25324334


O'Hartaigh B, Pahor M, Buford TW, Dodson JA, Forman DE and Gill TM: Physical activity and resting pulse rate in older adults: Findings from a randomized controlled trial. Am Heart J. 2014 Oct;168 (4) :597-604. Epub 2014 Jul 30. PMID: 25262271


O Hartaigh B, Gaksch M, Kienreich K, Grübler MR, Verheyen N, März W, Tomaschitz A, Gill TM and Pilz S: Associations of Daytime, Nighttime, and 24-Hour Heart Rate With Four Distinct Markers of Inflammation in Hypertensive Patients: The Styrian Hypertension Study. J Clin Hypertens (Greenwich). 2014 Sep 30; Epub 2014 Sep 30. PMID: 25266946


Malinis MF, Chen S, Allore HG and Quagliarello VJ: Outcomes Among Older Adult Liver Transplantation Recipients in the Model of End Stage Liver Disease (MELD) Era. Ann Transplant. 2014 Sep 26;19 :478-87. Epub 2014 Sep 26. PMID: 25256592


Graham-Steed TR, Soulos PR, Dearing N, Concato J, Tinetti ME and Gross CP: Development and validation of a prognostic index for fracture risk in older men undergoing prostate cancer treatment. J Geriatr Oncol. 2014 Sep 18; Epub 2014 Sep 18. PMID: 25240918


Della-Morte D, Wang L, Beecham A, Blanton SH, Zhao H, Sacco RL, Rundek T and Dong C: Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics. J Neurol Sci. 2014 Sep 15;344 (1-2) :27-31. Epub 2014 Jun 14. PMID: 24954085


Rabinowitz PM, Slizovskiy IB, Lamers V, Trufan SJ, Holford TR, Dziura JD, Peduzzi PN, Kane MJ, Reif JS, Weiss TR and Stowe MH: Proximity to Natural Gas Wells and Reported Health Status: Results of a Household Survey in Washington County, Pennsylvania. Environ Health Perspect. 2014 Sep 10; Epub 2014 Sep 10. PMID: 25204871


Erekson EA, Ciarleglio MM, Hanissian PD, Strohbehn K, Bynum JP and Fried TR: Functional Disability and Compromised Mobility Among Older Women With Urinary Incontinence. Female Pelvic Med Reconstr Surg. 2014 Sep 2; Epub 2014 Sep 2. PMID: 25185600


Xie P, Kranzler HR, Krystal JH, Farrer LA, Zhao H and Gelernter J: Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence. Addict Biol. 2014 Sep;19 (5) :955-64. Epub 2013 Jul 16. PMID: 23855403


Knauert MP, Yaggi HK, Redeker NS, Murphy TE, Araujo KL and Pisani MA: Feasibility study of unattended polysomnography in medical intensive care unit patients. Heart Lung. 2014 Sep-Oct;43 (5) :445-52. Epub 2014 Jul 12. PMID: 25023504


Zhang H, Wang F, Kranzler HR, Yang C, Xu H, Wang Z, Zhao H and Gelernter J: Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes. Hum Genet. 2014 Sep;133 (9) :1093-104. Epub 2014 Jun 3. PMID: 24889829


Case SM, O'Leary J, Kim N, Tinetti ME and Fried TR: Relationship between universal health outcome priorities and willingness to take medication for primary prevention of myocardial infarction. J Am Geriatr Soc. 2014 Sep;62 (9) :1753-8. Epub 2014 Aug 22. PMID: 25146885


Vaz Fragoso CA, Hsu FC, Brinkley T, Church T, Liu CK, Manini T, Newman AB, Stafford RS, McDermott MM and Gill TM: Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations. J Am Med Dir Assoc. 2014 Sep;15 (9) :665-70. Epub 2014 Jun 25. PMID: 24973990


Ó Hartaigh B, Gill TM, Shah I, Hughes AD, Deanfield JE, Kuh D and Hardy R: Association between resting heart rate across the life course and all-cause mortality: longitudinal findings from the Medical Research Council (MRC) National Survey of Health and Development (NSHD). J Epidemiol Community Health. 2014 Sep;68 (9) :883-9. Epub 2014 May 21. PMID: 24850484


Xu X, Liang J, Bennett JM, Botoseneanu A and Allore HG: Socioeconomic Stratification and Multidimensional Health Trajectories: Evidence of Convergence in Later Old Age. J Gerontol B Psychol Sci Soc Sci. 2014 Aug 26; Epub 2014 Aug 26. PMID: 25161216


Zapata HJ and Shaw AC: Aging of the human innate immune system in HIV infection. Curr Opin Immunol. 2014 Aug;29 :127-36. Epub 2014 Jul 2. PMID: 24997358


Gill TM: Disentangling the disabling process: insights from the precipitating events project. Gerontologist. 2014 Aug;54 (4) :533-49. PMID: 25035454


Lin H, Han L, Peduzzi PN, Murphy TE, Gill TM and Allore HG: A dynamic trajectory class model for intensive longitudinal categorical outcome. Stat Med. 2014 Jul 10;33 (15) :2645-64. Epub 2014 Feb 11. PMID: 24519416


Levy BR, Slade MD, Chung PH and Gill TM: Resiliency Over Time of Elders' Age Stereotypes After Encountering Stressful Events. J Gerontol B Psychol Sci Soc Sci. 2014 Jul 5; Epub 2014 Jul 5. PMID: 24997287


Ryslik GA, Cheng Y, Cheung KH, Bjornson RD, Zelterman D, Modis Y and Zhao H: A spatial simulation approach to account for protein structure when identifying non-random somatic mutations. BMC Bioinformatics. 2014 Jul 3;15 :231. Epub 2014 Jul 3. PMID: 24990767


Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H and Farrer LA: Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry. 2014 Jul 1;76 (1) :66-74. Epub 2013 Oct 19. PMID: 24143882


Amjad H, Towle V and Fried T: Association of experience with illness and end-of-life care with advance care planning in older adults. J Am Geriatr Soc. 2014 Jul;62 (7) :1304-9. Epub 2014 Jun 16. PMID: 24934237


Buurman BM, Trentalange M, Nicholson NR, McGloin JM, Gahbauer EA, Allore HG and Gill TM: Residential relocations among older people over the course of more than 10 years. J Am Med Dir Assoc. 2014 Jul;15 (7) :521-6. Epub 2014 May 1. PMID: 24794829


Thomas JM, O'Leary JR and Fried TR: A comparison of the willingness of resident and attending physicians to comply with the requests of patients at the end of life. J Gen Intern Med. 2014 Jul;29 (7) :1048-54. Epub 2014 Mar 20. PMID: 24647724


Lipska KJ, Ross JS, Wang Y, Inzucchi SE, Minges K, Karter AJ, Huang ES, Desai MM, Gill TM and Krumholz HM: National trends in US hospital admissions for hyperglycemia and hypoglycemia among Medicare beneficiaries, 1999 to 2011. JAMA Intern Med. 2014 Jul;174 (7) :1116-24. PMID: 24838229


Goyal G, Pisani MA, Murphy TE, Araujo KL and Puchalski JT: Advanced Diagnostic Bronchoscopy Using Conscious Sedation and the Laryngeal Nerve Block: Tolerability, Thoroughness, and Diagnostic Yield. Lung. 2014 Jun 28; Epub 2014 Jun 28. PMID: 24972639


Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM and Williamson JD: Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014 Jun 18;311 (23) :2387-96. PMID: 24866862


Zhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Geun Lee C, Elias JA and Herzog EL: Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis. Sci Transl Med. 2014 Jun 11;6 (240) :240ra76. PMID: 24920662


Chung LM, Colangelo CM and Zhao H: Data Pre-Processing for Label-Free Multiple Reaction Monitoring (MRM) Experiments. Biology (Basel). 2014 Jun 5;3 (2) :383-402. Epub 2014 Jun 5. PMID: 24905083


Vaz Fragoso CA, Miller ME, Fielding RA, King AC, Kritchevsky SB, McDermott MM, Myers V, Newman AB, Pahor M and Gill TM: Sleep-wake disturbances in sedentary community-dwelling elderly adults with functional limitations. J Am Geriatr Soc. 2014 Jun;62 (6) :1064-72. Epub 2014 Jun 2. PMID: 24889836


Nish SA, Schenten D, Wunderlich FT, Pope SD, Gao Y, Hoshi N, Yu S, Yan X, Lee HK, Pasman L, Brodsky I, Yordy B, Zhao H, Brüning J and Medzhitov R: T cell-intrinsic role of IL-6 signaling in primary and memory responses. Elife. 2014 May 19;3 :e01949. Epub 2014 May 19. PMID: 24842874


Hou L, Chen M, Zhang CK, Cho J and Zhao H: Guilt by rewiring: gene prioritization through network rewiring in genome wide association studies. Hum Mol Genet. 2014 May 15;23 (10) :2780-90. Epub 2013 Dec 30. PMID: 24381306


Lee N, Shin MS, Kang KS, Yoo SA, Mohanty S, Montgomery RR, Shaw AC and Kang I: Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling. Clin Immunol. 2014 May-Jun;152 (1-2) :101-10. Epub 2014 Mar 19. PMID: 24657713


Zhu R, Zhao H and Ma S: Identifying gene-environment and gene-gene interactions using a progressive penalization approach. Genet Epidemiol. 2014 May;38 (4) :353-68. Epub 2014 Apr 10. PMID: 24723356


Li C, Yang C, Gelernter J and Zhao H: Improving genetic risk prediction by leveraging pleiotropy. Hum Genet. 2014 May;133 (5) :639-50. Epub 2013 Dec 13. PMID: 24337655


Yang C, Li C, Kranzler HR, Farrer LA, Zhao H and Gelernter J: Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. Hum Genet. 2014 May;133 (5) :617-24. Epub 2013 Dec 3. PMID: 24297757


Mannam P, Shinn AS, Srivastava A, Neamu RF, Walker WE, Bohanon M, Merkel J, Kang MJ, Dela Cruz CS, Ahasic AM, Pisani MA, Trentalange M, West AP, Shadel GS, Elias JA and Lee PJ: MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2014 Apr 1;306 (7) :L604-19. Epub 2014 Jan 31. PMID: 24487387


Vaz Fragoso CA, Beavers DP, Hankinson JL, Flynn G, Berra K, Kritchevsky SB, Liu CK, McDermott MM, Manini TM, Rejeski WJ and Gill TM: Respiratory impairment and dyspnea and their associations with physical inactivity and mobility in sedentary community-dwelling older persons. J Am Geriatr Soc. 2014 Apr;62 (4) :622-8. Epub 2014 Mar 17. PMID: 24635756


Tinetti ME, Han L, Lee DS, McAvay GJ, Peduzzi P, Gross CP, Zhou B and Lin H: Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults. JAMA Intern Med. 2014 Apr;174 (4) :588-95. PMID: 24567036


Ryslik GA, Cheng Y, Cheung KH, Modis Y and Zhao H: A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations. BMC Bioinformatics. 2014 Mar 26;15 :86. Epub 2014 Mar 26. PMID: 24669769


Sauler M, Leng L, Trentalange M, Haslip M, Shan P, Piecychna M, Zhang Y, Andrews N, Mannam P, Allore H, Fried T, Bucala R and Lee PJ: Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15;306 (6) :L487-96. Epub 2014 Jan 17. PMID: 24441872


Kim M, Chen X, Chin LJ, Paranjape T, Speed WC, Kidd KK, Zhao H, Weidhaas JB and Slack FJ: Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases. Cell Cycle. 2014 Mar 15;13 (6) :1030-40. Epub 2014 Feb 3. PMID: 24552817


de Rekeneire N, Leo-Summers L, Han L and Gill TM: Epidemiology of restricting fatigue in older adults: the precipitating events project. J Am Geriatr Soc. 2014 Mar;62 (3) :476-81. Epub 2014 Feb 11. PMID: 24512073


Tinetti ME: The gap between clinical trials and the real world: extrapolating treatment effects from younger to older adults. JAMA Intern Med. 2014 Mar;174 (3) :397-8. PMID: 24424303


Lee DS, Markwardt S, McAvay GJ, Gross CP, Goeres LM, Han L, Peduzzi P, Lin H, Dodson JA and Tinetti ME: Effect of β-blockers on cardiac and pulmonary events and death in older adults with cardiovascular disease and chronic obstructive pulmonary disease. Med Care. 2014 Mar;52 Suppl 3 :S45-51. PMID: 24561758


Tinetti ME and Basu J: Research on multiple chronic conditions: where we are and where we need to go. Med Care. 2014 Mar;52 Suppl 3 :S3-6. PMID: 24561755


Erekson EA, Martin DK, Brousseau EC, Yip SO and Fried TR: Over-the-counter treatments and perineal hygiene in postmenopausal women. Menopause. 2014 Mar;21 (3) :281-5. PMID: 23880795


Li D, Sulovari A, Cheng C, Zhao H, Kranzler HR and Gelernter J: Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder. Neuropsychopharmacology. 2014 Mar;39 (4) :907-18. Epub 2013 Oct 18. PMID: 24136292


Reuben DB and Tinetti ME: The hospital-dependent patient. N Engl J Med. 2014 Feb 20;370 (8) :694-7. PMID: 24552316


Qian F, Guo X, Wang X, Yuan X, Chen S, Malawista SE, Bockenstedt LK, Allore HG and Montgomery RR: Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging. Aging (Albany NY). 2014 Feb;6 (2) :131-9. PMID: 24595889


Brummel NE, Jackson JC, Pandharipande PP, Thompson JL, Shintani AK, Dittus RS, Gill TM, Bernard GR, Ely EW and Girard TD: Delirium in the ICU and subsequent long-term disability among survivors of mechanical ventilation. Crit Care Med. 2014 Feb;42 (2) :369-77. PMID: 24158172


Brown JE, Evans BR, Zheng W, Obas V, Barrera-Martinez L, Egizi A, Zhao H, Caccone A and Powell JR: Human impacts have shaped historical and recent evolution in Aedes aegypti, the dengue and yellow fever mosquito. Evolution. 2014 Feb;68 (2) :514-25. Epub 2013 Oct 23. PMID: 24111703


Assis DN, Leng L, Du X, Zhang CK, Grieb G, Merk M, Garcia AB, McCrann C, Chapiro J, Meinhardt A, Mizue Y, Nikolic-Paterson DJ, Bernhagen J, Kaplan MM, Zhao H, Boyer JL and Bucala R: The role of macrophage migration inhibitory factor in autoimmune liver disease. Hepatology. 2014 Feb;59 (2) :580-91. Epub 2013 Dec 20. PMID: 23913513


Hartaigh BO, Allore HG, Trentalange M, McAvay G, Pilz S, Dodson JA and Gill TM: Elevations in time-varying resting heart rate predict subsequent all-cause mortality in older adults. Eur J Prev Cardiol. 2014 Jan 20; Epub 2014 Jan 20. PMID: 24445263


Schenten D, Nish SA, Yu S, Yan X, Lee HK, Brodsky I, Pasman L, Yordy B, Wunderlich FT, Brüning JC, Zhao H and Medzhitov R: Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells. Immunity. 2014 Jan 16;40 (1) :78-90. PMID: 24439266


Xu F, Li L, Schulz VP, Gallagher PG, Xiang B, Zhao H and Li P: Cytogenomic mapping and bioinformatic mining reveal interacting brain expressed genes for intellectual disability. Mol Cytogenet. 2014 Jan 10;7 (1) :4. Epub 2014 Jan 10. PMID: 24410907


Wang L, Rundek T, Beecham A, Hudson B, Blanton SH, Zhao H, Sacco RL and Dong C: Genome-wide interaction study identifies RCBTB1 as a modifier for smoking effect on carotid intima-media thickness. Arterioscler Thromb Vasc Biol. 2014 Jan;34 (1) :219-25. Epub 2013 Nov 7. PMID: 24202307


Sink KM, Espeland MA, Rushing J, Castro CM, Church TS, Cohen R, Gill TM, Henkin L, Jennings JM, Kerwin DR, Manini TM, Myers V, Pahor M, Reid KF, Woolard N, Rapp SR and Williamson JD: The LIFE Cognition Study: design and baseline characteristics. Clin Interv Aging. 2014;9 :1425-36. Epub 2014 Aug 27. PMID: 25210447


Makris UE, Fraenkel L, Han L, Leo-Summers L and Gill TM: Risk factors for restricting back pain in older persons. J Am Med Dir Assoc. 2014 Jan;15 (1) :62-7. Epub 2013 Nov 15. PMID: 24239445


Gupta AR, Pirruccello M, Cheng F, Kang HJ, Fernandez TV, Baskin JM, Choi M, Liu L, Ercan-Sencicek AG, Murdoch JD, Klei L, Neale BM, Franjic D, Daly MJ, Lifton RP, De Camilli P, Zhao H, Sestan N and State MW: Rare deleterious mutations of the gene EFR3A in autism spectrum disorders. Mol Autism. 2014;5 :31. Epub 2014 Apr 29. PMID: 24860643


Tinetti ME, Han L, McAvay GJ, Lee DS, Peduzzi P, Dodson JA, Gross CP, Zhou B and Lin H: Anti-hypertensive medications and cardiovascular events in older adults with multiple chronic conditions. PLoS One. 2014;9 (3) :e90733. Epub 2014 Mar 10. PMID: 24614535


Lorgunpai SJ, Grammas M, Lee DS, McAvay G, Charpentier P and Tinetti ME: Potential therapeutic competition in community-living older adults in the U.S.: use of medications that may adversely affect a coexisting condition. PLoS One. 2014;9 (2) :e89447. Epub 2014 Feb 25. PMID: 24586786

Panda A, Chen S, Shaw AC and Allore HG: Statistical approaches for analyzing immunologic data of repeated observations: a practical guide. J Immunol Methods. 2013 Dec 15;398-399 :19-26. Epub 2013 Sep 18. PMID: 24055129


Bikdeli B, Wang Y, Kim N, Desai MM, Quagliarello V and Krumholz HM: Trends in hospitalization rates and outcomes of endocarditis among Medicare beneficiaries. J Am Coll Cardiol. 2013 Dec 10;62 (23) :2217-26. Epub 2013 Aug 28. PMID: 23994421


Hou L and Zhao H: A review of post-GWAS prioritization approaches. Front Genet. 2013 Dec 9;4 :280. Epub 2013 Dec 9. PMID: 24367376


Han S, Yang BZ, Kranzler HR, Liu X, Zhao H, Farrer LA, Boerwinkle E, Potash JB and Gelernter J: Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. Am J Hum Genet. 2013 Dec 5;93 (6) :1027-34. Epub 2013 Nov 21. PMID: 24268660


Shaw AC, Goldstein DR and Montgomery RR: Age-dependent dysregulation of innate immunity. Nat Rev Immunol. 2013 Dec;13 (12) :875-87. Epub 2013 Oct 25. PMID: 24157572


Fried LF, Emanuele N, Zhang JH, Brophy M, Conner TA, Duckworth W, Leehey DJ, McCullough PA, O'Connor T, Palevsky PM, Reilly RF, Seliger SL, Warren SR, Watnick S, Peduzzi P and Guarino P: Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med. 2013 Nov 14;369 (20) :1892-903. Epub 2013 Nov 9. PMID: 24206457


Xie P, Kranzler HR, Yang C, Zhao H, Farrer LA and Gelernter J: Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry. 2013 Nov 1;74 (9) :656-63. Epub 2013 May 28. PMID: 23726511


Zhang S and Zhao H: Normalized modularity optimization method for community identification with degree adjustment. Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Nov;88 (5) :052802. Epub 2013 Nov 4. PMID: 24329313


Gill TM, Murphy TE, Gahbauer EA and Allore HG: The course of disability before and after a serious fall injury. JAMA Intern Med. 2013 Oct 28;173 (19) :1780-6. PMID: 23958741


Gao Y, Nish SA, Jiang R, Hou L, Licona-Limón P, Weinstein JS, Zhao H and Medzhitov R: Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity. 2013 Oct 17;39 (4) :722-32. Epub 2013 Sep 26. PMID: 24076050


Murphy TE, Baker DI, Leo-Summers LS, Allore HG and Tinetti ME: Association between treatment or usual care region and hospitalization for fall-related traumatic brain injury in the Connecticut Collaboration for Fall Prevention. J Am Geriatr Soc. 2013 Oct;61 (10) :1763-7. Epub 2013 Sep 19. PMID: 24083593


Vaz Fragoso CA, Van Ness PH, Araujo KL, Iannone LP and Marottoli RA: Sleep disturbances and driving practices of older drivers. J Am Geriatr Soc. 2013 Oct;61 (10) :1730-7. Epub 2013 Sep 3. PMID: 24001143


Fodeh SJ, Lazenby M, Bai M, Ercolano E, Murphy T and McCorkle R: Functional impairments as symptoms in the symptom cluster analysis of patients newly diagnosed with advanced cancer. J Pain Symptom Manage. 2013 Oct;46 (4) :500-10. Epub 2013 Feb 4. PMID: 23380336


Chaudhry SI, Murphy TE, Gahbauer E, Sussman LS, Allore HG and Gill TM: Restricting symptoms in the last year of life: a prospective cohort study. JAMA Intern Med. 2013 Sep 9;173 (16) :1534-40. PMID: 23836056


Pisani MA, Bramley K, Vest MT, Akgün KM, Araujo KL and Murphy TE: Patterns of opiate, benzodiazepine, and antipsychotic drug dosing in older patients in a medical intensive care unit. Am J Crit Care. 2013 Sep;22 (5) :e62-9. PMID: 23996429


Chen X, Slack FJ and Zhao H: Joint analysis of expression profiles from multiple cancers improves the identification of microRNA-gene interactions. Bioinformatics. 2013 Sep 1;29 (17) :2137-45. Epub 2013 Jun 14. PMID: 23772050


Erekson EA, Yip SO, Wedderburn TS, Martin DK, Li FY, Choi JN, Kenton KS and Fried TR: The Vulvovaginal Symptoms Questionnaire: a questionnaire for measuring vulvovaginal symptoms in postmenopausal women. Menopause. 2013 Sep;20 (9) :973-9. PMID: 23481118


Dziura JD, Post LA, Zhao Q, Fu Z and Peduzzi P: Strategies for dealing with missing data in clinical trials: from design to analysis. Yale J Biol Med. 2013 Sep;86 (3) :343-58. Epub 2013 Sep 20. PMID: 24058309


Gill TM, Murphy TE, Gahbauer EA and Allore HG: Association of injurious falls with disability outcomes and nursing home admissions in community-living older persons. Am J Epidemiol. 2013 Aug 1;178 (3) :418-25. Epub 2013 Apr 1. PMID: 23548756


Puchalski JT, Argento AC, Murphy TE, Araujo KL and Pisani MA: The safety of thoracentesis in patients with uncorrected bleeding risk. Ann Am Thorac Soc. 2013 Aug;10 (4) :336-41. PMID: 23952852


Case SM, Towle VR and Fried TR: Considering the balance: development of a scale to assess patient views on trade-offs in competing health outcomes. J Am Geriatr Soc. 2013 Aug;61 (8) :1331-6. Epub 2013 Jul 19. PMID: 23869795


Gancayco J, Soulos PR, Khiani V, Cramer LD, Ross JS, Genao I, Tinetti M and Gross CP: Age-based and sex-based disparities in screening colonoscopy use among medicare beneficiaries. J Clin Gastroenterol. 2013 Aug;47 (7) :630-6. PMID: 23619827


Horwitz LI, Jenq GY, Brewster UC, Chen C, Kanade S, Van Ness PH, Araujo KL, Ziaeian B, Moriarty JP, Fogerty RL and Krumholz HM: Comprehensive quality of discharge summaries at an academic medical center. J Hosp Med. 2013 Aug;8 (8) :436-43. Epub 2013 Mar 22. PMID: 23526813


Qian F, Chung L, Zheng W, Bruno V, Alexander RP, Wang Z, Wang X, Kurscheid S, Zhao H, Fikrig E, Gerstein M, Snyder M and Montgomery RR: Identification of genes critical for resistance to infection by West Nile virus using RNA-Seq analysis. Viruses. 2013 Jul 8;5 (7) :1664-81. Epub 2013 Jul 8. PMID: 23881275


Saxe JP, Chen M, Zhao H and Lin H: Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J. 2013 Jul 3;32 (13) :1869-85. Epub 2013 May 28. PMID: 23714778


Zhang CK, Hewett J, Hemming J, Grant T, Zhao H, Abraham C, Oikonomou I, Kanakia M, Cho JH and Proctor DD: The influence of depression on quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2013 Jul;19 (8) :1732-9. PMID: 23669400


Juthani-Mehta M, De Rekeneire N, Allore H, Chen S, O'Leary JR, Bauer DC, Harris TB, Newman AB, Yende S, Weyant RJ, Kritchevsky S and Quagliarello V: Modifiable risk factors for pneumonia requiring hospitalization of community-dwelling older adults: the Health, Aging, and Body Composition Study. J Am Geriatr Soc. 2013 Jul;61 (7) :1111-8. Epub 2013 Jun 17. PMID: 23772872


Botoseneanu A, Allore HG, Gahbauer EA and Gill TM: Long-term trajectories of lower extremity function in older adults: estimating gender differences while accounting for potential mortality bias. J Gerontol A Biol Sci Med Sci. 2013 Jul;68 (7) :861-8. Epub 2012 Nov 16. PMID: 23160367


Ma H and Zhao H: Drug target inference through pathway analysis of genomics data. Adv Drug Deliv Rev. 2013 Jun 30;65 (7) :966-72. Epub 2013 Jan 28. PMID: 23369829


Tinetti M: ACP Journal Club. Review: acute geriatric unit care reduces falls, delirium, and functional decline. Ann Intern Med. 2013 Jun 18;158 (12) :JC11. PMID: 23778923


Zhang H, Wang F, Kranzler HR, Zhao H and Gelernter J: Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls. PLoS One. 2013;8 (6) :e65648. Epub 2013 Jun 14. PMID: 23799031


Ryslik GA, Cheng Y, Cheung KH, Modis Y and Zhao H: Utilizing protein structure to identify non-random somatic mutations. BMC Bioinformatics. 2013 Jun 13;14 :190. Epub 2013 Jun 13. PMID: 23758891


Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, Romano-Adesman A, Bjornson RD, Breitbart RE, Brown KK, Carriero NJ, Cheung YH, Deanfield J, DePalma S, Fakhro KA, Glessner J, Hakonarson H, Italia MJ, Kaltman JR, Kaski J, Kim R, Kline JK, Lee T, Leipzig J, Lopez A, Mane SM, Mitchell LE, Newburger JW, Parfenov M, Pe'er I, Porter G, Roberts AE, Sachidanandam R, Sanders SJ, Seiden HS, State MW, Subramanian S, Tikhonova IR, Wang W, Warburton D, White PS, Williams IA, Zhao H, Seidman JG, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Seidman CE and Lifton RP: De novo mutations in histone-modifying genes in congenital heart disease. Nature. 2013 Jun 13;498 (7453) :220-3. Epub 2013 May 12. PMID: 23665959


Tinetti ME and Basch E: Patients' responsibility to participate in decision making and research. JAMA. 2013 Jun 12;309 (22) :2331-2. PMID: 23700165


Walke LM and Tinetti ME: ACE, MACE, and GRACE: time to put the pieces together: comment on "effects of an acute care for elders unit on costs and 30-day readmissions". JAMA Intern Med. 2013 Jun 10;173 (11) :987-9. PMID: 23608885


Akgün KM, Tate JP, Pisani M, Fried T, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC and Crothers K: Medical ICU admission diagnoses and outcomes in human immunodeficiency virus-infected and virus-uninfected veterans in the combination antiretroviral era. Crit Care Med. 2013 Jun;41 (6) :1458-67. PMID: 23507717


Ferguson J, Wheeler W, Fu Y, Prokunina-Olsson L, Zhao H and Sampson J: Statistical tests for detecting associations with groups of genetic variants: generalization, evaluation, and implementation. Eur J Hum Genet. 2013 Jun;21 (6) :680-6. Epub 2012 Oct 24. PMID: 23092956


Murphy TE, Baker DI, Leo-Summers LS, Bianco L, Gottschalk M, Acampora D and King MB: Integration of fall prevention into state policy in Connecticut. Gerontologist. 2013 Jun;53 (3) :508-15. Epub 2012 Oct 4. PMID: 23042690


Thomas JM, Cooney LM Jr and Fried TR: Systematic review: Health-related characteristics of elderly hospitalized adults and nursing home residents associated with short-term mortality. J Am Geriatr Soc. 2013 Jun;61 (6) :902-11. Epub 2013 May 20. PMID: 23692412


Fodeh SJ, Brandt C, Luong TB, Haddad A, Schultz M, Murphy T and Krauthammer M: Complementary ensemble clustering of biomedical data. J Biomed Inform. 2013 Jun;46 (3) :436-43. Epub 2013 Feb 27. PMID: 23454721


Kang KS, Lee N, Shin MS, Kim SD, Yu Y, Mohanty S, Belshe RB, Montgomery RR, Shaw AC and Kang I: An altered relationship of influenza vaccine-specific IgG responses with T cell immunity occurs with aging in humans. Clin Immunol. 2013 May;147 (2) :79-88. Epub 2013 Mar 15. PMID: 23578549


Horwitz LI, Dombroski J, Murphy TE, Farnan JM, Johnson JK and Arora VM: Validation of a handoff assessment tool: the Handoff CEX. J Clin Nurs. 2013 May;22 (9-10) :1477-86. Epub 2012 Jun 7. PMID: 22671983


Yang C, Wang L, Zhang S and Zhao H: Accounting for non-genetic factors by low-rank representation and sparse regression for eQTL mapping. Bioinformatics. 2013 Apr 15;29 (8) :1026-34. Epub 2013 Feb 17. PMID: 23419377


Gill TM, Gahbauer EA, Lin H, Han L and Allore HG: Comparisons between older men and women in the trajectory and burden of disability over the course of nearly 14 years. J Am Med Dir Assoc. 2013 Apr;14 (4) :280-6. Epub 2013 Jan 4. PMID: 23294968


Horwitz LI, Rand D, Staisiunas P, Van Ness PH, Araujo KL, Banerjee SS, Farnan JM and Arora VM: Development of a handoff evaluation tool for shift-to-shift physician handoffs: the Handoff CEX. J Hosp Med. 2013 Apr;8 (4) :191-200. PMID: 23559502


Pietrzak RH, Van Ness PH, Fried TR, Galea S and Norris FH: Trajectories of posttraumatic stress symptomatology in older persons affected by a large-magnitude disaster. J Psychiatr Res. 2013 Apr;47 (4) :520-6. Epub 2013 Jan 4. PMID: 23290559


Case SM, Fried TR and O'Leary J: How to ask: older adults' preferred tools in health outcome prioritization. Patient Educ Couns. 2013 Apr;91 (1) :29-36. Epub 2012 Dec 4. PMID: 23218242


Chung LM, Ferguson JP, Zheng W, Qian F, Bruno V, Montgomery RR and Zhao H: Differential expression analysis for paired RNA-Seq data. BMC Bioinformatics. 2013 Mar 27;14 :110. Epub 2013 Mar 27. PMID: 23530607


Zheng W and Zhao H: Studying the evolution of transcription factor binding events using multi-species ChIP-Seq data. Stat Appl Genet Mol Biol. 2013 Mar 26;12 (1) :1-15. Epub 2013 Mar 26. PMID: 23446869


Falzer PR, Leventhal HL, Peters E, Fried TR, Kerns R, Michalski M and Fraenkel L: The practitioner proposes a treatment change and the patient declines: what to do next? Pain Pract. 2013 Mar;13 (3) :215-26. Epub 2012 Jul 2. PMID: 23462141


Chaudhry SI, McAvay G, Chen S, Whitson H, Newman AB, Krumholz HM and Gill TM: Risk factors for hospital admission among older persons with newly diagnosed heart failure: findings from the Cardiovascular Health Study. J Am Coll Cardiol. 2013 Feb 12;61 (6) :635-42. PMID: 23391194


Han L, Allore H, Murphy T, Gill T, Peduzzi P and Lin H: Dynamics of functional aging based on latent-class trajectories of activities of daily living. Ann Epidemiol. 2013 Feb;23 (2) :87-92. PMID: 23305692


Qian F, Bolen CR, Jing C, Wang X, Zheng W, Zhao H, Fikrig E, Bruce RD, Kleinstein SH and Montgomery RR: Impaired toll-like receptor 3-mediated immune responses from macrophages of patients chronically infected with hepatitis C virus. Clin Vaccine Immunol. 2013 Feb;20 (2) :146-55. Epub 2012 Dec 5. PMID: 23220997


Puchalski JT, Argento AC, Murphy TE, Araujo KL, Oliva IB, Rubinowitz AN and Pisani MA: Etiologies of bilateral pleural effusions. Respir Med. 2013 Feb;107 (2) :284-91. Epub 2012 Dec 7. PMID: 23219348


Reilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA and Herzog EL: Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis. Am J Respir Crit Care Med. 2013 Jan 15;187 (2) :180-8. Epub 2012 Dec 6. PMID: 23220917


Zhang H, Herman AI, Kranzler HR, Anton RF, Zhao H, Zheng W and Gelernter J: Array-based profiling of DNA methylation changes associated with alcohol dependence. Alcohol Clin Exp Res. 2013 Jan;37 Suppl 1 :E108-15. Epub 2012 Aug 24. PMID: 22924764


Vaz Fragoso CA, Gill TM, McAvay G, Quanjer PH, Van Ness PH and Concato J: Respiratory impairment in older persons: when less means more. Am J Med. 2013 Jan;126 (1) :49-57. Epub 2012 Nov 20. PMID: 23177541


Lin H, Allore HG, McAvay G, Tinetti ME, Gill TM, Gross CP and Murphy TE: A method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome. Am J Public Health. 2013 Jan;103 (1) :177-82. Epub 2012 Apr 19. PMID: 22515873


Bruvik FK, Allore HG, Ranhoff AH and Engedal K: The effect of psychosocial support intervention on depression in patients with dementia and their family caregivers: an assessor-blinded randomized controlled trial. Dement Geriatr Cogn Dis Extra. 2013;3 (1) :386-97. Epub 2013 Oct 26. PMID: 24348500


Ning Y, McAvay G, Chaudhry SI, Arnold AM and Allore HG: Results differ by applying distinctive multiple imputation approaches on the longitudinal cardiovascular health study data. Exp Aging Res. 2013;39 (1) :27-43. PMID: 23316735


Chun H, Chen M, Li B and Zhao H: Joint conditional Gaussian graphical models with multiple sources of genomic data. Front Genet. 2013;4 :294. Epub 2013 Dec 17. PMID: 24381584


Ferguson JP, Cho JH, Yang C and Zhao H: Empirical Bayes correction for the Winner's Curse in genetic association studies. Genet Epidemiol. 2013 Jan;37 (1) :60-8. Epub 2012 Sep 25. PMID: 23012258


Allore HG, Ning Y, Brandt CA and Goulet JL: Accounting for the Hierarchical Structure in Veterans Health Administration Data: Differences in Healthcare Utilization between Men and Women Veterans. Int J Stat Med Res. 2013;2 (2) :94-103. PMID: 24910720


Akgün KM, Gordon K, Pisani M, Fried T, McGinnis KA, Tate JP, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC and Crothers K: Risk factors for hospitalization and medical intensive care unit (MICU) admission among HIV-infected Veterans. J Acquir Immune Defic Syndr. 2013 Jan 1;62 (1) :52-9. PMID: 23111572


Chen M, Gunel M and Zhao H: SomatiCA: identifying, characterizing and quantifying somatic copy number aberrations from cancer genome sequencing data. PLoS One. 2013;8 (11) :e78143. Epub 2013 Nov 12. PMID: 24265680


Dharmarajan K, Strait KM, Lagu T, Lindenauer PK, Tinetti ME, Lynn J, Li SX and Krumholz HM: Acute decompensated heart failure is routinely treated as a cardiopulmonary syndrome. PLoS One. 2013;8 (10) :e78222. Epub 2013 Oct 21. PMID: 24250751


Cone DC, Ahern J, Lee CH, Baker D, Murphy T and Bogucki S: A descriptive study of the "lift-assist" call. Prehosp Emerg Care. 2013 Jan-Mar;17 (1) :51-6. Epub 2012 Sep 12. PMID: 22971148

Levy BR, Slade MD, Murphy TE and Gill TM: Association between positive age stereotypes and recovery from disability in older persons. JAMA. 2012 Nov 21;308 (19) :1972-3. PMID: 23168819


Van Ness PH, Peduzzi PN and Quagliarello VJ: Efficacy and effectiveness as aspects of cluster randomized trials with nursing home residents: methodological insights from a pneumonia prevention trial. Contemp Clin Trials. 2012 Nov;33 (6) :1124-31. Epub 2012 Aug 11. PMID: 22917599


Ziaeian B, Araujo KL, Van Ness PH and Horwitz LI: Medication reconciliation accuracy and patient understanding of intended medication changes on hospital discharge. J Gen Intern Med. 2012 Nov;27 (11) :1513-20. Epub 2012 Jul 14. PMID: 22798200


Ma H and Zhao H: FacPad: Bayesian sparse factor modeling for the inference of pathways responsive to drug treatment. Bioinformatics. 2012 Oct 15;28 (20) :2662-70. Epub 2012 Aug 24. PMID: 22923307


Ge X, Ren Y, Bartulos O, Lee MY, Yue Z, Kim KY, Li W, Amos PJ, Bozkulak EC, Iyer A, Zheng W, Zhao H, Martin KA, Kotton DN, Tellides G, Park IH, Yue L and Qyang Y: Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells. Circulation. 2012 Oct 2;126 (14) :1695-704. Epub 2012 Aug 22. PMID: 22914687


Pietrzak RH, Van Ness PH, Fried TR, Galea S and Norris F: Diagnostic utility and factor structure of the PTSD Checklist in older adults. Int Psychogeriatr. 2012 Oct;24 (10) :1684-96. Epub 2012 May 30. PMID: 22647669


Chang SS, Chen S, McAvay GJ and Tinetti ME: Effect of coexisting chronic obstructive pulmonary disease and cognitive impairment on health outcomes in older adults. J Am Geriatr Soc. 2012 Oct;60 (10) :1839-46. Epub 2012 Oct 4. PMID: 23035917


Fried TR, Vaz Fragoso CA and Rabow MW: Caring for the older person with chronic obstructive pulmonary disease. JAMA. 2012 Sep 26;308 (12) :1254-63. PMID: 23011715


Lowthert L, Leffert J, Lin A, Umlauf S, Maloney K, Muralidharan A, Lorberg B, Mane S, Zhao H, Sinha R, Bhagwagar Z and Beech R: Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation. Biol Mood Anxiety Disord. 2012 Sep 12;2 (1) :15. Epub 2012 Sep 12. PMID: 22967286


Beech RD, Qu J, Leffert JJ, Lin A, Hong KA, Hansen J, Umlauf S, Mane S, Zhao H and Sinha R: Altered expression of cytokine signaling pathway genes in peripheral blood cells of alcohol dependent subjects: preliminary findings. Alcohol Clin Exp Res. 2012 Sep;36 (9) :1487-96. Epub 2012 Apr 4. PMID: 22471388


Erekson EA, Yip SO, Martin DK, Ciarleglio MM, Connell KA and Fried TR: Major postoperative complications after benign gynecologic surgery: a clinical prediction tool. Female Pelvic Med Reconstr Surg. 2012 Sep-Oct;18 (5) :274-80. PMID: 22983270


Chen X, Listman JB, Slack FJ, Gelernter J and Zhao H: Biases and errors on allele frequency estimation and disease association tests of next-generation sequencing of pooled samples. Genet Epidemiol. 2012 Sep;36 (6) :549-60. Epub 2012 Jun 6. PMID: 22674656


Li D, Zhao H and Gelernter J: Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases. Hum Genet. 2012 Aug;131 (8) :1361-74. Epub 2012 Apr 5. PMID: 22476623


Fraenkel L, Street RL Jr, Towle V, O'Leary JR, Iannone L, Van Ness PH and Fried TR: A pilot randomized controlled trial of a decision support tool to improve the quality of communication and decision-making in individuals with atrial fibrillation. J Am Geriatr Soc. 2012 Aug;60 (8) :1434-41. Epub 2012 Aug 2. PMID: 22861171


Tinetti ME, Charpentier P, Gottschalk M and Baker DI: Effect of a restorative model of posthospital home care on hospital readmissions. J Am Geriatr Soc. 2012 Aug;60 (8) :1521-6. Epub 2012 Aug 2. PMID: 22860756


Tinetti ME, McAvay GJ, Murphy TE, Gross CP, Lin H and Allore HG: Contribution of individual diseases to death in older adults with multiple diseases. J Am Geriatr Soc. 2012 Aug;60 (8) :1448-56. Epub 2012 Jun 26. PMID: 22734792


Ma H and Zhao H: iFad: an integrative factor analysis model for drug-pathway association inference. Bioinformatics. 2012 Jul 15;28 (14) :1911-8. Epub 2012 May 10. PMID: 22581178


Fraenkel L, Peters E, Charpentier P, Olsen B, Errante L, Schoen RT and Reyna V: Decision tool to improve the quality of care in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2012 Jul;64 (7) :977-85. PMID: 22392766


Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH and Gill TM: Respiratory impairment and COPD hospitalisation in older persons: a competing risk analysis. Eur Respir J. 2012 Jul;40 (1) :37-44. Epub 2012 Jan 20. PMID: 22267770


Lee DS, de Rekeneire N, Hanlon JT, Gill TM, Bauer DC, Meibohm B, Harris TB and Jeffery SM: Cognitive Impairment and Medication Complexity in Community-Living Older Adults: The Health, Aging and Body Composition Study. J Pharm Technol. 2012 Jul 1;28 (4) :156-162. PMID: 24660166


Tinetti ME, Fried TR and Boyd CM: Designing health care for the most common chronic condition--multimorbidity. JAMA. 2012 Jun 20;307 (23) :2493-4. PMID: 22797447


Erekson EA, Ratner ES, Walke LM and Fried TR: Gynecologic surgery in the geriatric patient. Obstet Gynecol. 2012 Jun;119 (6) :1262-9. PMID: 22617593


Jenq G and Tinetti ME: The journey across the health care (dis)continuum for vulnerable patients: policies, pitfalls, and possibilities. JAMA. 2012 May 23;307 (20) :2157-8. PMID: 22618921


Dodson JA, Arnold SV, Reid KJ, Gill TM, Rich MW, Masoudi FA, Spertus JA, Krumholz HM and Alexander KP: Physical function and independence 1 year after myocardial infarction: observations from the Translational Research Investigating Underlying disparities in recovery from acute Myocardial infarction: Patients' Health status registry. Am Heart J. 2012 May;163 (5) :790-6. PMID: 22607856


Nunez-Smith M, Ciarleglio MM, Sandoval-Schaefer T, Elumn J, Castillo-Page L, Peduzzi P and Bradley EH: Institutional variation in the promotion of racial/ethnic minority faculty at US medical schools. Am J Public Health. 2012 May;102 (5) :852-8. Epub 2012 Mar 15. PMID: 22420820


Li D, Zhao H and Gelernter J: Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians. Hum Genet. 2012 May;131 (5) :725-37. Epub 2011 Nov 20. PMID: 22102315


Fraenkel L, Falzer P, Fried T, Kohler M, Peters E, Kerns R and Leventhal H: Measuring pain impact versus pain severity using a numeric rating scale. J Gen Intern Med. 2012 May;27 (5) :555-60. Epub 2011 Nov 12. PMID: 22081365


Li D, Zhao H, Kranzler HR, Oslin D, Anton RF, Farrer LA and Gelernter J: Association of COL25A1 with comorbid antisocial personality disorder and substance dependence. Biol Psychiatry. 2012 Apr 15;71 (8) :733-40. Epub 2012 Jan 31. PMID: 22297151


Zhang CK, Stein PB, Liu J, Wang Z, Yang R, Cho JH, Gregersen PK, Aerts JM, Zhao H, Pastores GM and Mistry PK: Genome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variation. Am J Hematol. 2012 Apr;87 (4) :377-83. Epub 2012 Mar 3. PMID: 22388998


Morino K, Petersen KF, Sono S, Choi CS, Samuel VT, Lin A, Gallo A, Zhao H, Kashiwagi A, Goldberg IJ, Wang H, Eckel RH, Maegawa H and Shulman GI: Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes. Diabetes. 2012 Apr;61 (4) :877-87. Epub 2012 Feb 24. PMID: 22368174


Tinetti ME: The retreat from advanced care planning. JAMA. 2012 Mar 7;307 (9) :915-6. PMID: 22396510


Chen D, Zheng W, Lin A, Uyhazi K, Zhao H and Lin H: Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol. 2012 Mar 6;22 (5) :420-5. Epub 2012 Feb 16. PMID: 22342750


Santoro N, Zhang CK, Zhao H, Pakstis AJ, Kim G, Kursawe R, Dykas DJ, Bale AE, Giannini C, Pierpont B, Shaw MM, Groop L and Caprio S: Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents. Hepatology. 2012 Mar;55 (3) :781-9. Epub 2011 Dec 18. PMID: 22105854


Volkova M, Zhang Y, Shaw AC and Lee PJ: The role of Toll-like receptors in age-associated lung diseases. J Gerontol A Biol Sci Med Sci. 2012 Mar;67 (3) :247-53. Epub 2012 Mar 5. PMID: 22396470


Vaz Fragoso CA and Gill TM: Respiratory impairment and the aging lung: a novel paradigm for assessing pulmonary function. J Gerontol A Biol Sci Med Sci. 2012 Mar;67 (3) :264-75. Epub 2011 Dec 1. PMID: 22138206


Carling T, Carty SE, Ciarleglio MM, Cooper DS, Doherty GM, Kim LT, Kloos RT, Mazzaferri EL Sr, Peduzzi PN, Roman SA, Sippel RS, Sosa JA, Stack BC Jr, Steward DL, Tufano RP, Tuttle RM and Udelsman R: American Thyroid Association design and feasibility of a prospective randomized controlled trial of prophylactic central lymph node dissection for papillary thyroid carcinoma. Thyroid. 2012 Mar;22 (3) :237-44. Epub 2012 Feb 7. PMID: 22313454


Ferguson JP, Cho JH and Zhao H: A new approach for the joint analysis of multiple ChIP-seq libraries with application to histone modification. Stat Appl Genet Mol Biol. 2012 Feb 10;11 (3) :Article 1. Epub 2012 Feb 10. PMID: 22499701


Qian F, Wang X, Zhang L, Chen S, Piecychna M, Allore H, Bockenstedt L, Malawista S, Bucala R, Shaw AC, Fikrig E and Montgomery RR: Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly. Aging Cell. 2012 Feb;11 (1) :104-10. Epub 2011 Nov 28. PMID: 22023165


Li G, Gelernter J, Kranzler HR and Zhao H: M(3): an improved SNP calling algorithm for Illumina BeadArray data. Bioinformatics. 2012 Feb 1;28 (3) :358-65. Epub 2011 Dec 8. PMID: 22155947


Van Ness PH, Murphy TE, Araujo KL and Pisani MA: Multivariate graphical methods provide an insightful way to formulate explanatory hypotheses from limited categorical data. J Clin Epidemiol. 2012 Feb;65 (2) :179-88. Epub 2011 Sep 1. PMID: 21889310


Gill TM, Gahbauer EA, Murphy TE, Han L and Allore HG: Risk factors and precipitants of long-term disability in community mobility: a cohort study of older persons. Ann Intern Med. 2012 Jan 17;156 (2) :131-40. PMID: 22250144


Vaz Fragoso CA, Enright PL, McAvay G, Van Ness PH and Gill TM: Frailty and respiratory impairment in older persons. Am J Med. 2012 Jan;125 (1) :79-86. PMID: 22195532


Han L, Kim N, Brandt C and Allore HG: Antidepressant use and cognitive deficits in older men: addressing confounding by indications with different methods. Ann Epidemiol. 2012 Jan;22 (1) :9-16. Epub 2011 Oct 28. PMID: 22037381


Li B, Chuns H and Zhao H: Sparse Estimation of Conditional Graphical Models With Application to Gene Networks. J Am Stat Assoc. 2012 Jan 1;107 (497) :152-167. PMID: 24574574


Zuo L, Gelernter J, Zhang CK, Zhao H, Lu L, Kranzler HR, Malison RT, Li CS, Wang F, Zhang XY, Deng HW, Krystal JH, Zhang F and Luo X: Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology. 2012 Jan;37 (2) :557-66. Epub 2011 Sep 28. PMID: 21956439


Fried TR, Redding CA, Robbins ML, Paiva A, O'Leary JR and Iannone L: Promoting advance care planning as health behavior change: development of scales to assess Decisional Balance, Medical and Religious Beliefs, and Processes of Change. Patient Educ Couns. 2012 Jan;86 (1) :25-32. Epub 2011 Jul 7. PMID: 21741194


Zhang W, Ferguson J, Ng SM, Hui K, Goh G, Lin A, Esplugues E, Flavell RA, Abraham C, Zhao H and Cho JH: Effector CD4+ T cell expression signatures and immune-mediated disease associated genes. PLoS One. 2012;7 (6) :e38510. Epub 2012 Jun 8. PMID: 22715389

Carling T, Carty SE, Ciarleglio MM, Cooper DS, Doherty G, Kim LT, Kloos RT, Mazzaferri E, Peduzzi PN, Roman S, Sippel RS, Sosa JA, Stack BC, Steward D, Tufano R, Tuttle RM and Udelsman R: American Thyroid Association (ATA) - Design and Feasibility of a Prospective Randomized Controlled Trial of Prophylactic Central Lymph Node Dissection for Papillary Thyroid Carcinoma. Thyroid. 2011 Dec 9; Epub 2011 Dec 9. PMID: 22150591


Murphy TE, Van Ness PH, Araujo KL and Pisani MA: Bayesian time-series analysis of a repeated-measures poisson outcome with excess zeroes. Am J Epidemiol. 2011 Dec 1;174 (11) :1230-7. Epub 2011 Oct 24. PMID: 22025357


Gross CP, Soulos PR, Ross JS, Cramer LD, Guerrero C, Tinetti ME and Braithwaite RS: Assessing the impact of screening colonoscopy on mortality in the medicare population. J Gen Intern Med. 2011 Dec;26 (12) :1441-9. Epub 2011 Aug 13. PMID: 21842323


Li G, Ferguson J, Zheng W, Lee JS, Zhang X, Li L, Kang J, Yan X and Zhao H: Large-scale risk prediction applied to Genetic Analysis Workshop 17 mini-exome sequence data. BMC Proc. 2011 Nov 29;5 Suppl 9 :S46. Epub 2011 Nov 29. PMID: 22373389


Yan X, Li L, Lee JS, Zheng W, Ferguson J and Zhao H: Detecting functional rare variants by collapsing and incorporating functional annotation in Genetic Analysis Workshop 17 mini-exome data. BMC Proc. 2011 Nov 29;5 Suppl 9 :S27. Epub 2011 Nov 29. PMID: 22373324


Kang J, Zheng W, Li L, Lee JS, Yan X and Zhao H: Use of Bayesian networks to dissect the complexity of genetic disease: application to the Genetic Analysis Workshop 17 simulated data. BMC Proc. 2011 Nov 29;5 Suppl 9 :S37. Epub 2011 Nov 29. PMID: 22373110


Gill TM, Gahbauer EA, Han L and Allore HG: The relationship between intervening hospitalizations and transitions between frailty states. J Gerontol A Biol Sci Med Sci. 2011 Nov;66 (11) :1238-43. Epub 2011 Aug 17. PMID: 21852286


Vaz Fragoso CA, Gill TM, McAvay G, Van Ness PH, Yaggi HK and Concato J: Use of lambda-mu-sigma-derived Z score for evaluating respiratory impairment in middle-aged persons. Respir Care. 2011 Nov;56 (11) :1771-7. Epub 2011 May 20. PMID: 21605489


Fraenkel L, Street RL Jr and Fried TR: Development of a tool to improve the quality of decision making in atrial fibrillation. BMC Med Inform Decis Mak. 2011 Oct 6;11 :59. Epub 2011 Oct 6. PMID: 21977943


Carlson Scholz JA, Garg R, Compton SR, Allore HG, Zeiss CJ and Uchio EM: Poliomyelitis in MuLV-infected ICR-SCID mice after injection of basement membrane matrix contaminated with lactate dehydrogenase-elevating virus. Comp Med. 2011 Oct;61 (5) :404-11. PMID: 22330347


Fragoso CA, Concato J, McAvay G, Yaggi HK, Van Ness PH and Gill TM: Staging the severity of chronic obstructive pulmonary disease in older persons based on spirometric Z-scores. J Am Geriatr Soc. 2011 Oct;59 (10) :1847-54. Epub 2011 Sep 13. PMID: 22091498


Vaz Fragoso CA, Gill TM, McAvay G, Yaggi HK, Van Ness PH and Concato J: Respiratory impairment and mortality in older persons: a novel spirometric approach. J Investig Med. 2011 Oct;59 (7) :1089-95. PMID: 22011620


Van Ness PH, Fried TR and Gill TM: Mixed Methods for the Interpretation of Longitudinal Gerontologic Data: Insights From Philosophical Hermeneutics. J Mix Methods Res. 2011 Oct;5 (4) :293-308. Epub 2011 Jul 13. PMID: 22582035


Erekson EA, Yip SO, Ciarleglio MM and Fried TR: Postoperative complications after gynecologic surgery. Obstet Gynecol. 2011 Oct;118 (4) :785-93. PMID: 21934441


Kato M, Chen X, Inukai S, Zhao H and Slack FJ: Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans. RNA. 2011 Oct;17 (10) :1804-20. Epub 2011 Aug 2. PMID: 21810936


Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H and Gelernter J: Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry. 2011 Sep 15;70 (6) :528-36. Epub 2011 Jun 17. PMID: 21683344


Li D, Zhao H and Gelernter J: Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases. Biol Psychiatry. 2011 Sep 15;70 (6) :504-12. Epub 2011 Apr 17. PMID: 21497796


Barry LC, Murphy TE and Gill TM: Depressive symptoms and functional transitions over time in older persons. Am J Geriatr Psychiatry. 2011 Sep;19 (9) :783-91. PMID: 21873834


Chun H, Ballard DH, Cho J and Zhao H: Identification of association between disease and multiple markers via sparse partial least-squares regression. Genet Epidemiol. 2011 Sep;35 (6) :479-86. Epub 2011 Jun 15. PMID: 21678491


Tinetti ME, McAvay G, Chang SS, Ning Y, Newman AB, Fitzpatrick A, Fried TR, Harris TB, Nevitt MC, Satterfield S, Yaffe K and Peduzzi P: Effect of chronic disease-related symptoms and impairments on universal health outcomes in older adults. J Am Geriatr Soc. 2011 Sep;59 (9) :1618-27. Epub 2011 Aug 24. PMID: 21883120


Tinetti ME, McAvay GJ, Chang SS, Newman AB, Fitzpatrick AL, Fried TR and Peduzzi PN: Contribution of multiple chronic conditions to universal health outcomes. J Am Geriatr Soc. 2011 Sep;59 (9) :1686-91. Epub 2011 Aug 30. PMID: 21883118


Chaudhry SI, McAvay G, Ning Y, Allore HG, Newman AB and Gill TM: Risk factors for onset of disability among older persons newly diagnosed with heart failure: the Cardiovascular Health Study. J Card Fail. 2011 Sep;17 (9) :764-70. PMID: 21872147


Han L, McCusker J, Cole M, Capek R and Abrahamowicz M: Antidepressant use and cognitive functioning in older medical patients with major or minor depression: a prospective cohort study with database linkage. J Clin Psychopharmacol. 2011 Aug;31 (4) :429-35. PMID: 21694621


Zheng W, Chung LM and Zhao H: Bias detection and correction in RNA-Sequencing data. BMC Bioinformatics. 2011 Jul 19;12 :290. Epub 2011 Jul 19. PMID: 21771300


Shaw AC, Panda A, Joshi SR, Qian F, Allore HG and Montgomery RR: Dysregulation of human Toll-like receptor function in aging. Ageing Res Rev. 2011 Jul;10 (3) :346-53. Epub 2010 Nov 10. PMID: 21074638


Barry LC, Murphy TE and Gill TM: Depression and functional recovery after a disabling hospitalization in older persons. J Am Geriatr Soc. 2011 Jul;59 (7) :1320-5. Epub 2011 Jun 13. PMID: 21668916


Tinetti ME and Studenski SA: Comparative effectiveness research and patients with multiple chronic conditions. N Engl J Med. 2011 Jun 30;364 (26) :2478-81. Epub 2011 Jun 22. PMID: 21696327


Kang J, Kugathasan S, Georges M, Zhao H and Cho JH: Improved risk prediction for Crohn's disease with a multi-locus approach. Hum Mol Genet. 2011 Jun 15;20 (12) :2435-42. Epub 2011 Mar 22. PMID: 21427131


Fried TR, Redding CA, Robbins ML, O'Leary JR and Iannone L: Agreement between older persons and their surrogate decision-makers regarding participation in advance care planning. J Am Geriatr Soc. 2011 Jun;59 (6) :1105-9. Epub 2011 Jun 7. PMID: 21649619


Fried TR, Tinetti ME, Towle V, O'Leary JR and Iannone L: Effects of benefits and harms on older persons' willingness to take medication for primary cardiovascular prevention. Arch Intern Med. 2011 May 23;171 (10) :923-8. Epub 2011 Feb 28. PMID: 21357797


Qian F, Wang X, Zhang L, Lin A, Zhao H, Fikrig E and Montgomery RR: Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus. J Infect Dis. 2011 May 15;203 (10) :1415-24. Epub 2011 Mar 11. PMID: 21398396


Ma H, Schadt EE, Kaplan LM and Zhao H: COSINE: COndition-SpecIfic sub-NEtwork identification using a global optimization method. Bioinformatics. 2011 May 1;27 (9) :1290-8. Epub 2011 Mar 16. PMID: 21414987


Fried TR, Tinetti M, Agostini J, Iannone L and Towle V: Health outcome prioritization to elicit preferences of older persons with multiple health conditions. Patient Educ Couns. 2011 May;83 (2) :278-82. Epub 2010 May 31. PMID: 20570078


Quagliarello V: Dissemination of Neisseria meningitidis. N Engl J Med. 2011 Apr 21;364 (16) :1573-5. PMID: 21506747


Lee JS, Choi M, Yan X, Lifton RP and Zhao H: On optimal pooling designs to identify rare variants through massive resequencing. Genet Epidemiol. 2011 Apr;35 (3) :139-47. Epub 2011 Jan 19. PMID: 21254222


Makris UE, Fraenkel L, Han L, Leo-Summers L and Gill TM: Epidemiology of restricting back pain in community-living older persons. J Am Geriatr Soc. 2011 Apr;59 (4) :610-4. Epub 2011 Mar 15. PMID: 21410444


Qi X and Zhao H: Some theoretical properties of Silverman's method for Smoothed functional principal component analysis. J Multivar Anal. 2011 Apr 1;102 (4) :741-767. PMID: 21516205


Doernberg S, Schaaf B, Dalhoff K, Leng L, Beitin A, Quagliarello V and Bucala R: Association of macrophage migration inhibitory factor (MIF) polymorphisms with risk of meningitis from Streptococcus pneumoniae. Cytokine. 2011 Mar;53 (3) :292-4. Epub 2011 Jan 3. PMID: 21208809


Chang X, Liu F, Wang X, Lin A, Zhao H and Su B: The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation. Immunity. 2011 Feb 25;34 (2) :201-12. Epub 2011 Feb 17. PMID: 21333552


Vest MT, Murphy TE, Araujo KL and Pisani MA: Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study. Health Qual Life Outcomes. 2011 Feb 5;9 :9. Epub 2011 Feb 5. PMID: 21294911


Fried TR, Tinetti ME and Iannone L: Primary care clinicians' experiences with treatment decision making for older persons with multiple conditions. Arch Intern Med. 2011 Jan 10;171 (1) :75-80. Epub 2010 Sep 13. PMID: 20837819


Luo R and Zhao H: BAYESIAN HIERARCHICAL MODELING FOR SIGNALING PATHWAY INFERENCE FROM SINGLE CELL INTERVENTIONAL DATA. Ann Appl Stat. 2011;5 (2A) :725-745. PMID: 22162986


Zheng W, Gianoulis TA, Karczewski KJ, Zhao H and Snyder M: Regulatory variation within and between species. Annu Rev Genomics Hum Genet. 2011;12 :327-46. PMID: 21721942


Li L, Zheng W, Lee JS, Zhang X, Ferguson J, Yan X and Zhao H: Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data. BMC Proc. 2011;5 (Suppl 9 Genetic Analysis Workshop 17: Unraveling Human Exome DataS Ghosh, H Bickeboller, J Bailey, JE Bailey-Wilson, R Cantor, W Daw, AL DeStefano, CD Engelman, A Hinrichs, J Houwing-Duistermaat, IR Konig, J Kent Jr., N Pankratz, A Paterson, E Pugh, Y Sun, A Thomas, N Tintle, X Zhu, JW MacCluer and L Almasy) :S117. Epub 2011 Nov 29. PMID: 22373309


Das R, Towle V, Van Ness PH and Juthani-Mehta M: Adverse outcomes in nursing home residents with increased episodes of observed bacteriuria. Infect Control Hosp Epidemiol. 2011 Jan;32 (1) :84-6. Epub 2010 Nov 22. PMID: 21091203


Chang SS, Vaz Fragoso CA, Van Ness PH, Fried LP and Tinetti ME: Association between combined interleukin-6 and C-reactive protein levels and pulmonary function in older women: results from the Women's Health and Aging Studies I and II. J Am Geriatr Soc. 2011 Jan;59 (1) :113-9. PMID: 21226682


Zuo L, Zhang CK, Wang F, Li CS, Zhao H, Lu L, Zhang XY, Lu L, Zhang H, Zhang F, Krystal JH and Luo X: A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. PLoS One. 2011;6 (11) :e26726. Epub 2011 Nov 7. PMID: 22096494

Berger C, Hoffmann K, Vasquez JG, Mane S, Lewis J, Filler R, Lin A, Zhao H, Durazzo T, Baird A, Lin W, Foss F, Christensen I, Girardi M, Tigelaar R and Edelson R: Rapid generation of maturationally synchronized human dendritic cells: contribution to the clinical efficacy of extracorporeal photochemotherapy. Blood. 2010 Dec 2;116 (23) :4838-47. Epub 2010 Aug 18. PMID: 20720185


Peduzzi P, Kyriakides T, O'Connor TZ, Guarino P, Warren SR and Huang GD: Methodological issues in comparative effectiveness research: clinical trials. Am J Med. 2010 Dec;123 (12 Suppl 1) :e8-15. PMID: 21184867


Huang S, Tong T and Zhao H: Bias-corrected diagonal discriminant rules for high-dimensional classification. Biometrics. 2010 Dec;66 (4) :1096-106. PMID: 20222939


Beech RD, Lowthert L, Leffert JJ, Mason PN, Taylor MM, Umlauf S, Lin A, Lee JY, Maloney K, Muralidharan A, Lorberg B, Zhao H, Newton SS, Mane S, Epperson CN, Sinha R, Blumberg H and Bhagwagar Z: Increased peripheral blood expression of electron transport chain genes in bipolar depression. Bipolar Disord. 2010 Dec;12 (8) :813-24. PMID: 21176028


Fried TR, Redding CA, Robbins ML, Paiva A, O'Leary JR and Iannone L: Stages of change for the component behaviors of advance care planning. J Am Geriatr Soc. 2010 Dec;58 (12) :2329-36. PMID: 21143441


Lipska KJ, De Rekeneire N, Van Ness PH, Johnson KC, Kanaya A, Koster A, Strotmeyer ES, Goodpaster BH, Harris T, Gill TM and Inzucchi SE: Identifying dysglycemic states in older adults: implications of the emerging use of hemoglobin A1c. J Clin Endocrinol Metab. 2010 Dec;95 (12) :5289-95. Epub 2010 Sep 22. PMID: 20861123


Mistry PK, Liu J, Yang M, Nottoli T, McGrath J, Jain D, Zhang K, Keutzer J, Chuang WL, Mehal WZ, Zhao H, Lin A, Mane S, Liu X, Peng YZ, Li JH, Agrawal M, Zhu LL, Blair HC, Robinson LJ, Iqbal J, Sun L and Zaidi M: Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proc Natl Acad Sci U S A. 2010 Nov 9;107 (45) :19473-8. Epub 2010 Oct 20. PMID: 20962279


Gill TM, Allore HG, Gahbauer EA and Murphy TE: Change in disability after hospitalization or restricted activity in older persons. JAMA. 2010 Nov 3;304 (17) :1919-28. PMID: 21045098


Juthani-Mehta M and Quagliarello VJ: Infectious diseases in the nursing home setting: challenges and opportunities for clinical investigation. Clin Infect Dis. 2010 Oct 15;51 (8) :931-6. PMID: 20822459


Santoro N, Kursawe R, D'Adamo E, Dykas DJ, Zhang CK, Bale AE, Calí AM, Narayan D, Shaw MM, Pierpont B, Savoye M, Lartaud D, Eldrich S, Cushman SW, Zhao H, Shulman GI and Caprio S: A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. Hepatology. 2010 Oct;52 (4) :1281-90. PMID: 20803499


Gill TM: Assessment of function and disability in longitudinal studies. J Am Geriatr Soc. 2010 Oct;58 Suppl 2 :S308-12. PMID: 21029059


Vaz Fragoso CA, Araujo KL, Van Ness PH and Marottoli RA: Sleep disturbances and adverse driving events in a predominantly male cohort of active older drivers. J Am Geriatr Soc. 2010 Oct;58 (10) :1878-84. PMID: 20929465


Dávalos A, Fernández-Hernando C, Sowa G, Derakhshan B, Lin MI, Lee JY, Zhao H, Luo R, Colangelo C and Sessa WC: Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells. Mol Cell Proteomics. 2010 Oct;9 (10) :2109-24. Epub 2010 Jun 28. PMID: 20585024


Chaudhry SI, McAvay G, Ning Y, Allore HG, Newman AB and Gill TM: Geriatric impairments and disability: the cardiovascular health study. J Am Geriatr Soc. 2010 Sep;58 (9) :1686-92. PMID: 20863328


Hu JX, Zhao H and Zhou HH: False Discovery Rate Control With Groups. J Am Stat Assoc. 2010 Sep 1;105 (491) :1215-1227. PMID: 21931466


Pisani MA, Murphy TE, Araujo KL and Van Ness PH: Factors associated with persistent delirium after intensive care unit admission in an older medical patient population. J Crit Care. 2010 Sep;25 (3) :540.e1-7. Epub 2010 Apr 22. PMID: 20413252


Shaw AC, Joshi S, Greenwood H, Panda A and Lord JM: Aging of the innate immune system. Curr Opin Immunol. 2010 Aug;22 (4) :507-13. PMID: 20667703


Concato J, Peduzzi P, Huang GD, O'Leary TJ and Kupersmith J: Comparative effectiveness research: what kind of studies do we need? J Investig Med. 2010 Aug;58 (6) :764-9. PMID: 20479661


Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK and Gill TM: Chronic obstructive pulmonary disease in older persons: A comparison of two spirometric definitions. Respir Med. 2010 Aug;104 (8) :1189-96. Epub 2010 Mar 3. PMID: 20199857


Van Ness PH, Charpentier PA, Ip EH, Leng X, Murphy TE, Tooze JA and Allore HG: Gerontologic biostatistics: the statistical challenges of clinical research with older study participants. J Am Geriatr Soc. 2010 Jul;58 (7) :1386-92. Epub 2010 Jun 1. PMID: 20533963


Dunne DW, Shaw A, Bockenstedt LK, Allore HG, Chen S, Malawista SE, Leng L, Mizue Y, Piecychna M, Zhang L, Towle V, Bucala R, Montgomery RR and Fikrig E: Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults. PLoS One. 2010 Jun 28;5 (6) :e11343. Epub 2010 Jun 28. PMID: 20596538


Mathai SK, Gulati M, Peng X, Russell TR, Shaw AC, Rubinowitz AN, Murray LA, Siner JM, Antin-Ozerkis DE, Montgomery RR, Reilkoff RA, Bucala RJ and Herzog EL: Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Lab Invest. 2010 Jun;90 (6) :812-23. Epub 2010 Apr 19. PMID: 20404807


Zheng W, Zhao H, Mancera E, Steinmetz LM and Snyder M: Genetic analysis of variation in transcription factor binding in yeast. Nature. 2010 Apr 22;464 (7292) :1187-91. Epub 2010 Mar 17. PMID: 20237471


Ballard DH, Cho J and Zhao H: Comparisons of multi-marker association methods to detect association between a candidate region and disease. Genet Epidemiol. 2010 Apr;34 (3) :201-12. PMID: 19810024


Gill TM, Gahbauer EA, Han L and Allore HG: Trajectories of disability in the last year of life. N Engl J Med. 2010 Apr 1;362 (13) :1173-80. PMID: 20357280


Fraenkel L and Fried TR: Individualized medical decision making: necessary, achievable, but not yet attainable. Arch Intern Med. 2010 Mar 22;170 (6) :566-9. PMID: 20308644


Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK and Gill TM: The ratio of FEV1 to FVC as a basis for establishing chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Mar 1;181 (5) :446-51. Epub 2009 Dec 17. PMID: 20019341


Murphy TE, Gaughan M, Hume R and Moore SG Jr: College Graduation Rates for Minority Students in a Selective Technical University: Will Participation in a Summer Bridge Program Contribute to Success? Educ Eval Policy Anal. 2010 Mar;32 (1) :70-83. PMID: 23136456


Ahluwalia SC, Gill TM, Baker DI and Fried TR: Perspectives of older persons on bathing and bathing disability: a qualitative study. J Am Geriatr Soc. 2010 Mar;58 (3) :450-6. Epub 2010 Feb 11. PMID: 20158554


Kang J, Cho J and Zhao H: Practical issues in building risk-predicting models for complex diseases. J Biopharm Stat. 2010 Mar;20 (2) :415-40. PMID: 20309766


Panda A, Qian F, Mohanty S, van Duin D, Newman FK, Zhang L, Chen S, Towle V, Belshe RB, Fikrig E, Allore HG, Montgomery RR and Shaw AC: Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol. 2010 Mar 1;184 (5) :2518-27. Epub 2010 Jan 25. PMID: 20100933


Chaudhry SI, Wang Y, Gill TM and Krumholz HM: Geriatric conditions and subsequent mortality in older patients with heart failure. J Am Coll Cardiol. 2010 Jan 26;55 (4) :309-16. PMID: 20117435


Fried TR and Drickamer M: Garnering support for advance care planning. JAMA. 2010 Jan 20;303 (3) :269-70. PMID: 20085956


Tinetti ME and Kumar C: The patient who falls: "It's always a trade-off". JAMA. 2010 Jan 20;303 (3) :258-66. PMID: 20085954


Van Ness PH, Allore HG, Fried TR and Lin H: Inverse intensity weighting in generalized linear models as an option for analyzing longitudinal data with triggered observations. Am J Epidemiol. 2010 Jan 1;171 (1) :105-12. Epub 2009 Nov 25. PMID: 19942574


Akgün KM, Murphy TE, Araujo KL, Van Ness PH and Pisani M: Does gender impact intensity of care provided to older medical intensive care unit patients? Crit Care Res Pract. 2010;2010 :404608. Epub 2010 Oct 20. PMID: 20981259


Mustavich LF, Miller P, Kidd KK and Zhao H: Using a pharmacokinetic model to relate an individual's susceptibility to alcohol dependence to genotypes. Hum Hered. 2010;70 (3) :177-93. Epub 2010 Aug 12. PMID: 20714161

Ballard DH, Aporntewan C, Lee JY, Lee JS, Wu Z and Zhao H: A pathway analysis applied to Genetic Analysis Workshop 16 genome-wide rheumatoid arthritis data. BMC Proc. 2009 Dec 15;3 Suppl 7 :S91. Epub 2009 Dec 15. PMID: 20018088


Wu Z, Aporntewan C, Ballard DH, Lee JY, Lee JS and Zhao H: Two-stage joint selection method to identify candidate markers from genome-wide association studies. BMC Proc. 2009 Dec 15;3 Suppl 7 :S29. Epub 2009 Dec 15. PMID: 20018019


Aporntewan C, Ballard DH, Lee JY, Lee JS, Wu Z and Zhao H: Gene hunting of the Genetic Analysis Workshop 16 rheumatoid arthritis data using rough set theory. BMC Proc. 2009 Dec 15;3 Suppl 7 :S126. Epub 2009 Dec 15. PMID: 20017992


Pisani MA, Kong SY, Kasl SV, Murphy TE, Araujo KL and Van Ness PH: Days of delirium are associated with 1-year mortality in an older intensive care unit population. Am J Respir Crit Care Med. 2009 Dec 1;180 (11) :1092-7. Epub 2009 Sep 10. PMID: 19745202


Han L: Top cited papers in International Psychogeriatrics: 6c. Tracking cognitive decline in Alzheimer's disease using the Mini-mental State Examination: a meta-analysis ("mini" is not necessarily trivial!). Int Psychogeriatr. 2009 Dec;21 (6) :1037-40. Epub 2009 Sep 14. PMID: 19747422


Barry LC, Allore HG, Bruce ML and Gill TM: Longitudinal association between depressive symptoms and disability burden among older persons. J Gerontol A Biol Sci Med Sci. 2009 Dec;64 (12) :1325-32. Epub 2009 Sep 23. PMID: 19776217


Gill TM, Gahbauer EA, Han L and Allore HG: Factors associated with recovery of prehospital function among older persons admitted to a nursing home with disability after an acute hospitalization. J Gerontol A Biol Sci Med Sci. 2009 Dec;64 (12) :1296-303. Epub 2009 Aug 6. PMID: 19661289


Sun N and Zhao H: Reconstructing transcriptional regulatory networks through genomics data. Stat Methods Med Res. 2009 Dec;18 (6) :595-617. PMID: 20048387


Joshi SR, Shaw AC and Quagliarello VJ: Pandemic influenza H1N1 2009, innate immunity, and the impact of immunosenescence on influenza vaccine. Yale J Biol Med. 2009 Dec;82 (4) :143-51. PMID: 20027279


Das R, Perrelli E, Towle V, Van Ness PH and Juthani-Mehta M: Antimicrobial susceptibility of bacteria isolated from urine samples obtained from nursing home residents. Infect Control Hosp Epidemiol. 2009 Nov;30 (11) :1116-9. PMID: 19785518


Vaz Fragoso CA, Gahbauer EA, Van Ness PH and Gill TM: Sleep-wake disturbances and frailty in community-living older persons. J Am Geriatr Soc. 2009 Nov;57 (11) :2094-100. Epub 2009 Sep 30. PMID: 19793356


Luo R, Colangelo CM, Sessa WC and Zhao H: Bayesian Analysis of iTRAQ Data with Nonrandom Missingness: Identification of Differentially Expressed Proteins. Stat Biosci. 2009 Nov;1 (2) :228-245. PMID: 21927625


Gill TM, Van Ness PH and Gahbauer EA: Factors associated with accurate recall of prior disability in older persons. J Am Geriatr Soc. 2009 Oct;57 (10) :1897-901. Epub 2009 Sep 8. PMID: 19737329


Gill TM, Murphy TE, Barry LC and Allore HG: Risk factors for disability subtypes in older persons. J Am Geriatr Soc. 2009 Oct;57 (10) :1850-5. Epub 2009 Aug 20. PMID: 19694870


Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK and Gill TM: Defining chronic obstructive pulmonary disease in older persons. Respir Med. 2009 Oct;103 (10) :1468-76. Epub 2009 May 21. PMID: 19464159


Fried TR, Bullock K, Iannone L and O'Leary JR: Understanding advance care planning as a process of health behavior change. J Am Geriatr Soc. 2009 Sep;57 (9) :1547-55. Epub 2009 Aug 4. PMID: 19682120


Thomas JM, O'Leary JR and Fried TR: Understanding their options: determinants of hospice discussion for older persons with advanced illness. J Gen Intern Med. 2009 Aug;24 (8) :923-8. Epub 2009 Jun 9. PMID: 19506972


Mendu ML, McAvay G, Lampert R, Stoehr J and Tinetti ME: Yield of diagnostic tests in evaluating syncopal episodes in older patients. Arch Intern Med. 2009 Jul 27;169 (14) :1299-305. PMID: 19636031


Quagliarello V, Juthani-Mehta M, Ginter S, Towle V, Allore H and Tinetti M: Pilot testing of intervention protocols to prevent pneumonia in nursing home residents. J Am Geriatr Soc. 2009 Jul;57 (7) :1226-31. Epub 2009 Jun 3. PMID: 19558483


Wu Z and Zhao H: Statistical power of model selection strategies for genome-wide association studies. PLoS Genet. 2009 Jul;5 (7) :e1000582. Epub 2009 Jul 31. PMID: 19649321


Panda A, Arjona A, Sapey E, Bai F, Fikrig E, Montgomery RR, Lord JM and Shaw AC: Human innate immunosenescence: causes and consequences for immunity in old age. Trends Immunol. 2009 Jul;30 (7) :325-33. Epub 2009 Jun 21. PMID: 19541535


Gill TM, Gahbauer EA and Van Ness PH: Psychometric properties of a scale to assess the severity of bathing disability. Arch Phys Med Rehabil. 2009 Jun;90 (6) :987-93. PMID: 19480875


Juthani-Mehta M, Quagliarello V, Perrelli E, Towle V, Van Ness PH and Tinetti M: Clinical features to identify urinary tract infection in nursing home residents: a cohort study. J Am Geriatr Soc. 2009 Jun;57 (6) :963-70. PMID: 19490243


Sampson JN and Zhao H: Genotyping and inflated type I error rate in genome-wide association case/control studies. BMC Bioinformatics. 2009 Feb 23;10 :68. Epub 2009 Feb 23. PMID: 19236714


Gill TM, Gahbauer EA, Han L and Allore HG: Functional trajectories in older persons admitted to a nursing home with disability after an acute hospitalization. J Am Geriatr Soc. 2009 Feb;57 (2) :195-201. Epub 2008 Dec 11. PMID: 19170778


Jiao Y, Tausta SL, Gandotra N, Sun N, Liu T, Clay NK, Ceserani T, Chen M, Ma L, Holford M, Zhang HY, Zhao H, Deng XW and Nelson T: A transcriptome atlas of rice cell types uncovers cellular, functional and developmental hierarchies. Nat Genet. 2009 Feb;41 (2) :258-63. Epub 2009 Jan 4. PMID: 19122662


Datta D and Zhao H: Effect of false positive and false negative rates on inference of binding target conservation across different conditions and species from ChIP-chip data. BMC Bioinformatics. 2009 Jan 19;10 :23. Epub 2009 Jan 19. PMID: 19152696


Holford ME, Rajeevan H, Zhao H, Kidd KK and Cheung KH: Semantic Web-based integration of cancer pathways and allele frequency data. Cancer Inform. 2009 Jan 15;8 :19-30. Epub 2009 Jan 15. PMID: 19458791


Pisani MA, Murphy TE, Araujo KL, Slattum P, Van Ness PH and Inouye SK: Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population. Crit Care Med. 2009 Jan;37 (1) :177-83. PMID: 19050611


Sampson J and Zhao H: Identifying individuals in a complex mixture of DNA with unknown ancestry. Stat Appl Genet Mol Biol. 2009;8 :Article 37. Epub 2009 Sep 9. PMID: 19799556

Budel S, Padukkavidana T, Liu BP, Feng Z, Hu F, Johnson S, Lauren J, Park JH, McGee AW, Liao J, Stillman A, Kim JE, Yang BZ, Sodi S, Gelernter J, Zhao H, Hisama F, Arnsten AF and Strittmatter SM: Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci. 2008 Dec 3;28 (49) :13161-72. PMID: 19052207


Yang BZ, Kranzler HR, Zhao H, Gruen JR, Luo X and Gelernter J: Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence. Alcohol Clin Exp Res. 2008 Dec;32 (12) :2117-27. Epub 2008 Sep 30. PMID: 18828801


Lin H, Guo Z, Peduzzi PN, Gill TM and Allore HG: A semiparametric transition model with latent traits for longitudinal multistate data. Biometrics. 2008 Dec;64 (4) :1032-42. Epub 2008 Mar 19. PMID: 18355385


Rothman MD, Leo-Summers L and Gill TM: Prognostic significance of potential frailty criteria. J Am Geriatr Soc. 2008 Dec;56 (12) :2211-116. PMID: 19093920


Han L, Agostini JV and Allore HG: Cumulative anticholinergic exposure is associated with poor memory and executive function in older men. J Am Geriatr Soc. 2008 Dec;56 (12) :2203-10. PMID: 19093918


Fried TR, McGraw S, Agostini JV and Tinetti ME: Views of older persons with multiple morbidities on competing outcomes and clinical decision-making. J Am Geriatr Soc. 2008 Oct;56 (10) :1839-44. Epub 2008 Sep 2. PMID: 18771453


Fried TR and O'Leary JR: Using the experiences of bereaved caregivers to inform patient- and caregiver-centered advance care planning. J Gen Intern Med. 2008 Oct;23 (10) :1602-7. Epub 2008 Jul 30. PMID: 18665427


Han L, McCusker J, Cole M, Abrahamowicz M and Capek R: 12-month cognitive outcomes of major and minor depression in older medical patients. Am J Geriatr Psychiatry. 2008 Sep;16 (9) :742-51. PMID: 18757768


Murphy TE, Agostini JV, Van Ness PH, Peduzzi P, Tinetti ME and Allore HG: Assessing multiple medication use with probabilities of benefits and harms. J Aging Health. 2008 Sep;20 (6) :694-709. Epub 2008 Jul 14. PMID: 18625759


Lai JM, Gill TM, Cooney LM, Bradley EH, Hawkins KA and Karlawish JH: Everyday decision-making ability in older persons with cognitive impairment. Am J Geriatr Psychiatry. 2008 Aug;16 (8) :693-6. PMID: 18669948


Xiang B, Li A, Valentin D, Nowak NJ, Zhao H and Li P: Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay. Am J Med Genet A. 2008 Aug 1;146A (15) :1942-54. PMID: 18627053


Van Ness PH, Towle VR, O'Leary JR and Fried TR: Religion, risk, and medical decision making at the end of life. J Aging Health. 2008 Aug;20 (5) :545-59. Epub 2008 Apr 28. PMID: 18443144


Tinetti ME, McAvay GJ, Fried TR, Allore HG, Salmon JC, Foody JM, Bianco L, Ginter S and Fraenkel L: Health outcome priorities among competing cardiovascular, fall injury, and medication-related symptom outcomes. J Am Geriatr Soc. 2008 Aug;56 (8) :1409-16. Epub 2008 Jul 24. PMID: 18662210


Tinetti ME, Baker DI, King M, Gottschalk M, Murphy TE, Acampora D, Carlin BP, Leo-Summers L and Allore HG: Effect of dissemination of evidence in reducing injuries from falls. N Engl J Med. 2008 Jul 17;359 (3) :252-61. PMID: 18635430


Juthani-Mehta M and Quagliarello V: Five key principles of a successful clinical research career in infectious diseases. Curr Infect Dis Rep. 2008 Jul;10 (4) :259-61. PMID: 18765109


Vaz Fragoso CA, Araujo KL, Van Ness PH and Marottoli RA: Prevalence of sleep disturbances in a cohort of older drivers. J Gerontol A Biol Sci Med Sci. 2008 Jul;63 (7) :715-23. PMID: 18693226


Tinetti ME: Over-the-counter sales of statins and other drugs for asymptomatic conditions. N Engl J Med. 2008 Jun 19;358 (25) :2728-32. PMID: 18565867


Fragoso CA, Gahbauer EA, Van Ness PH, Concato J and Gill TM: Peak expiratory flow as a predictor of subsequent disability and death in community-living older persons. J Am Geriatr Soc. 2008 Jun;56 (6) :1014-20. Epub 2008 Apr 18. PMID: 18422951


Gill TM and Gahbauer EA: Evaluating disability over discrete periods of time. J Gerontol A Biol Sci Med Sci. 2008 Jun;63 (6) :588-94. PMID: 18559633


Juthani-Mehta M, Tinetti M, Perrelli E, Towle V, Van Ness PH and Quagliarello V: Interobserver variability in the assessment of clinical criteria for suspected urinary tract infection in nursing home residents. Infect Control Hosp Epidemiol. 2008 May;29 (5) :446-9. PMID: 18419369


Ji W, Foo JN, O'Roak BJ, Zhao H, Larson MG, Simon DB, Newton-Cheh C, State MW, Levy D and Lifton RP: Rare independent mutations in renal salt handling genes contribute to blood pressure variation. Nat Genet. 2008 May;40 (5) :592-9. Epub 2008 Apr 6. PMID: 18391953


Tinetti ME, McAvay GJ, Fried TR, Foody JM, Bianco L, Ginter S and Fraenkel L: Development of a tool for eliciting patient priority from among competing cardiovascular disease, medication-symptoms, and fall injury outcomes. J Am Geriatr Soc. 2008 Apr;56 (4) :730-6. Epub 2008 Feb 11. PMID: 18266842


Mohanty S, Town T, Yagi T, Scheidig C, Kwan KY, Allore HG, Flavell RA and Shaw AC: Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta. Proc Natl Acad Sci U S A. 2008 Apr 1;105 (13) :5063-8. Epub 2008 Mar 26. PMID: 18367668


Van Ness PH, Towle VR and Juthani-Mehta M: Testing measurement reliability in older populations: methods for informed discrimination in instrument selection and application. J Aging Health. 2008 Mar;20 (2) :183-97. Epub 2007 Dec 18. PMID: 18089767


Gill TM, Guo Z and Allore HG: Subtypes of disability in older persons over the course of nearly 8 years. J Am Geriatr Soc. 2008 Mar;56 (3) :436-43. Epub 2008 Jan 5. PMID: 18194225


Datta D and Zhao H: Statistical methods to infer cooperative binding among transcription factors in Saccharomyces cerevisiae. Bioinformatics. 2008 Feb 15;24 (4) :545-52. Epub 2007 Nov 7. PMID: 17989095


Pang H and Zhao H: Building pathway clusters from Random Forests classification using class votes. BMC Bioinformatics. 2008 Feb 6;9 :87. Epub 2008 Feb 6. PMID: 18254968


Barry LC, Allore HG, Guo Z, Bruce ML and Gill TM: Higher burden of depression among older women: the effect of onset, persistence, and mortality over time. Arch Gen Psychiatry. 2008 Feb;65 (2) :172-8. PMID: 18250255


Bartali B, Frongillo EA, Guralnik JM, Stipanuk MH, Allore HG, Cherubini A, Bandinelli S, Ferrucci L and Gill TM: Serum micronutrient concentrations and decline in physical function among older persons. JAMA. 2008 Jan 23;299 (3) :308-15. PMID: 18212315


Yagi T, Giallourakis C, Mohanty S, Scheidig C, Shen J, Zheng H, Xavier RJ and Shaw AC: Defective signal transduction in B lymphocytes lacking presenilin proteins. Proc Natl Acad Sci U S A. 2008 Jan 22;105 (3) :979-84. Epub 2008 Jan 14. PMID: 18195359


Allore HG and Murphy TE: An examination of effect estimation in factorial and standardly-tailored designs. Clin Trials. 2008;5 (2) :121-30. PMID: 18375650

Singh B, Wilson JH, Vasavada HH, Guo Z, Allore HG and Zeiss CJ: Motor deficits and altered striatal gene expression in aphakia (ak) mice. Brain Res. 2007 Dec 14;1185 :283-92. Epub 2007 Sep 16. PMID: 17949697


Walke LM, Byers AL, Tinetti ME, Dubin JA, McCorkle R and Fried TR: Range and severity of symptoms over time among older adults with chronic obstructive pulmonary disease and heart failure. Arch Intern Med. 2007 Dec 10;167 (22) :2503-8. PMID: 18071174


Yang BZ, Kranzler HR, Zhao H, Gruen JR, Luo X and Gelernter J: Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. Hum Mol Genet. 2007 Dec 1;16 (23) :2844-53. Epub 2007 Aug 30. PMID: 17761687


Dinu V, Zhao H and Miller PL: Integrating domain knowledge with statistical and data mining methods for high-density genomic SNP disease association analysis. J Biomed Inform. 2007 Dec;40 (6) :750-60. Epub 2007 Jun 10. PMID: 17625973


Van Ness PH, Murphy TE, Araujo KL, Pisani MA and Allore HG: The use of missingness screens in clinical epidemiologic research has implications for regression modeling. J Clin Epidemiol. 2007 Dec;60 (12) :1239-45. Epub 2007 Jul 25. PMID: 17998078


Agostini JV, Tinetti ME, Han L, Peduzzi P, Foody JM and Concato J: Association between antihypertensive medication use and non-cardiovascular outcomes in older men. J Gen Intern Med. 2007 Dec;22 (12) :1661-7. Epub 2007 Sep 25. PMID: 17899299


Vaz Fragoso CA and Gill TM: Sleep complaints in community-living older persons: a multifactorial geriatric syndrome. J Am Geriatr Soc. 2007 Nov;55 (11) :1853-66. Epub 2007 Oct 3. PMID: 17916123


Gill TM, Han L and Allore HG: Bath aids and the subsequent development of bathing disability in community-living older persons. J Am Geriatr Soc. 2007 Nov;55 (11) :1757-63. Epub 2007 Oct 3. PMID: 17916117


Cosgriff JA, Pisani M, Bradley EH, O'Leary JR and Fried TR: The association between treatment preferences and trajectories of care at the end-of-life. J Gen Intern Med. 2007 Nov;22 (11) :1566-71. Epub 2007 Sep 14. PMID: 17874168


Concato J, Aslan M, Palmisano MM, Doebbeling CC, Peduzzi P, Ofek K, Soreq H and Doebbeling B: Acetylcholinesterase activity in veterans of the first Gulf War. J Investig Med. 2007 Nov;55 (7) :360-7. PMID: 18062897


Chaudhry SI, Wang Y, Concato J, Gill TM and Krumholz HM: Patterns of weight change preceding hospitalization for heart failure. Circulation. 2007 Oct 2;116 (14) :1549-54. Epub 2007 Sep 10. PMID: 17846286


Vaz Fragoso CA, Gahbauer EA, Van Ness PH and Gill TM: Reporting peak expiratory flow in older persons. J Gerontol A Biol Sci Med Sci. 2007 Oct;62 (10) :1147-51. PMID: 17921429


Marottoli RA, Ness PH, Araujo KL, Iannone LP, Acampora D, Charpentier P and Peduzzi P: A randomized trial of an education program to enhance older driver performance. J Gerontol A Biol Sci Med Sci. 2007 Oct;62 (10) :1113-9. PMID: 17921424


Kim I, Liu Y and Zhao H: Bayesian methods for predicting interacting protein pairs using domain information. Biometrics. 2007 Sep;63 (3) :824-33. PMID: 17825014


van Duin D and Shaw AC: Toll-like receptors in older adults. J Am Geriatr Soc. 2007 Sep;55 (9) :1438-44. PMID: 17767688


Fraenkel L, Rabidou N, Wittink D and Fried T: Improving informed decision-making for patients with knee pain. J Rheumatol. 2007 Sep;34 (9) :1894-8. Epub 2007 Aug 1. PMID: 17696268


Pisani MA, Murphy TE, Van Ness PH, Araujo KL and Inouye SK: Characteristics associated with delirium in older patients in a medical intensive care unit. Arch Intern Med. 2007 Aug 13-27;167 (15) :1629-34. PMID: 17698685


Juthani-Mehta M, Tinetti M, Perrelli E, Towle V and Quagliarello V: Role of dipstick testing in the evaluation of urinary tract infection in nursing home residents. Infect Control Hosp Epidemiol. 2007 Jul;28 (7) :889-91. Epub 2007 May 17. PMID: 17564998


Juthani-Mehta M, Tinetti M, Perrelli E, Towle V, Van Ness PH and Quagliarello V: Diagnostic accuracy of criteria for urinary tract infection in a cohort of nursing home residents. J Am Geriatr Soc. 2007 Jul;55 (7) :1072-7. PMID: 17608881


Fried TR, O'Leary J, Van Ness P and Fraenkel L: Inconsistency over time in the preferences of older persons with advanced illness for life-sustaining treatment. J Am Geriatr Soc. 2007 Jul;55 (7) :1007-14. PMID: 17608872


Rothman MD, Van Ness PH, O'Leary JR and Fried TR: Refusal of medical and surgical interventions by older persons with advanced chronic disease. J Gen Intern Med. 2007 Jul;22 (7) :982-7. Epub 2007 May 5. PMID: 17483977


Gross CP, McAvay GJ, Guo Z and Tinetti ME: The impact of chronic illnesses on the use and effectiveness of adjuvant chemotherapy for colon cancer. Cancer. 2007 Jun 15;109 (12) :2410-9. PMID: 17510973


van Duin D, Allore HG, Mohanty S, Ginter S, Newman FK, Belshe RB, Medzhitov R and Shaw AC: Prevaccine determination of the expression of costimulatory B7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults. J Infect Dis. 2007 Jun 1;195 (11) :1590-7. Epub 2007 Apr 17. PMID: 17471428


Chou WC, Cooney LM Jr, Van Ness PH, Allore HG and Gill TM: Access to primary care for Medicare beneficiaries. J Am Geriatr Soc. 2007 May;55 (5) :763-8. PMID: 17493198


McAvay GJ, Van Ness PH, Bogardus ST Jr, Zhang Y, Leslie DL, Leo-Summers LS and Inouye SK: Depressive symptoms and the risk of incident delirium in older hospitalized adults. J Am Geriatr Soc. 2007 May;55 (5) :684-91. PMID: 17493187


Marottoli RA, Allore H, Araujo KL, Iannone LP, Acampora D, Gottschalk M, Charpentier P, Kasl S and Peduzzi P: A randomized trial of a physical conditioning program to enhance the driving performance of older persons. J Gen Intern Med. 2007 May;22 (5) :590-7. PMID: 17443366


Dinu V, Miller PL and Zhao H: Evidence for association between multiple complement pathway genes and AMD. Genet Epidemiol. 2007 Apr;31 (3) :224-37. PMID: 17266113


Gill TM, Han L and Allore HG: Predisposing factors and precipitants for bathing disability in older persons. J Am Geriatr Soc. 2007 Apr;55 (4) :534-40. PMID: 17397431


Fried TR, Van Ness PH, Byers AL, Towle VR, O'Leary JR and Dubin JA: Changes in preferences for life-sustaining treatment among older persons with advanced illness. J Gen Intern Med. 2007 Apr;22 (4) :495-501. PMID: 17372799


Agostini JV, Tinetti ME, Han L, McAvay G, Foody JM and Concato J: Effects of statin use on muscle strength, cognition, and depressive symptoms in older adults. J Am Geriatr Soc. 2007 Mar;55 (3) :420-5. PMID: 17341246


Lee J, He K, Stolc V, Lee H, Figueroa P, Gao Y, Tongprasit W, Zhao H, Lee I and Deng XW: Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development. Plant Cell. 2007 Mar;19 (3) :731-49. Epub 2007 Mar 2. PMID: 17337630


van Duin D, Mohanty S, Thomas V, Ginter S, Montgomery RR, Fikrig E, Allore HG, Medzhitov R and Shaw AC: Age-associated defect in human TLR-1/2 function. J Immunol. 2007 Jan 15;178 (2) :970-5. PMID: 17202359


Huang S, Ballard D and Zhao H: The role of heritability in mapping expression quantitative trait loci. BMC Proc. 2007;1 Suppl 1 :S86. Epub 2007 Dec 18. PMID: 18466589


Peduzzi P, Guo Z, Marottoli RA, Gill TM, Araujo K and Allore HG: Improved self-confidence was a mechanism of action in two geriatric trials evaluating physical interventions. J Clin Epidemiol. 2007 Jan;60 (1) :94-102. Epub 2006 Sep 28. PMID: 17161760


Walke LM, Byers AL, Gallo WT, Endrass J and Fried TR: The association of symptoms with health outcomes in chronically ill adults. J Pain Symptom Manage. 2007 Jan;33 (1) :58-66. PMID: 17196907


Lee TS, Mane S, Eid T, Zhao H, Lin A, Guan Z, Kim JH, Schweitzer J, King-Stevens D, Weber P, Spencer SS, Spencer DD and de Lanerolle NC: Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. Mol Med. 2007 Jan-Feb;13 (1-2) :1-13. PMID: 17515952

Gross CP, Andersen MS, Krumholz HM, McAvay GJ, Proctor D and Tinetti ME: Relation between Medicare screening reimbursement and stage at diagnosis for older patients with colon cancer. JAMA. 2006 Dec 20;296 (23) :2815-22. PMID: 17179458


Tinetti ME, Gordon C, Sogolow E, Lapin P and Bradley EH: Fall-risk evaluation and management: challenges in adopting geriatric care practices. Gerontologist. 2006 Dec;46 (6) :717-25. PMID: 17169927


Gross CP, Guo Z, McAvay GJ, Allore HG, Young M and Tinetti ME: Multimorbidity and survival in older persons with colorectal cancer. J Am Geriatr Soc. 2006 Dec;54 (12) :1898-904. PMID: 17198496


Gross CP, McAvay GJ, Krumholz HM, Paltiel AD, Bhasin D and Tinetti ME: The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening. Ann Intern Med. 2006 Nov 7;145 (9) :646-53. PMID: 17088577


Wu SP, Leng L, Feng Z, Liu N, Zhao H, McDonald C, Lee A, Arnett FC, Gregersen PK, Mayes MD and Bucala R: Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis Rheum. 2006 Nov;54 (11) :3661-9. PMID: 17075815


Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ and Fu XY: A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006 Oct 17;6 :48. Epub 2006 Oct 17. PMID: 17044933


Gill TM, Guo Z and Allore HG: The epidemiology of bathing disability in older persons. J Am Geriatr Soc. 2006 Oct;54 (10) :1524-30. PMID: 17038069


Pang H, Lin A, Holford M, Enerson BE, Lu B, Lawton MP, Floyd E and Zhao H: Pathway analysis using random forests classification and regression. Bioinformatics. 2006 Aug 15;22 (16) :2028-36. Epub 2006 Jun 29. PMID: 16809386


McAvay GJ, Van Ness PH, Bogardus ST Jr, Zhang Y, Leslie DL, Leo-Summers LS and Inouye SK: Older adults discharged from the hospital with delirium: 1-year outcomes. J Am Geriatr Soc. 2006 Aug;54 (8) :1245-50. PMID: 16913993


Gill TM, Allore HG and Han L: Bathing disability and the risk of long-term admission to a nursing home. J Gerontol A Biol Sci Med Sci. 2006 Aug;61 (8) :821-5. PMID: 16912099


Tsubouchi T, Zhao H and Roeder GS: The meiosis-specific zip4 protein regulates crossover distribution by promoting synaptonemal complex formation together with zip2. Dev Cell. 2006 Jun;10 (6) :809-19. PMID: 16740482


Guarino P, Lamping DL, Elbourne D, Carpenter J and Peduzzi P: A brief measure of perceived understanding of informed consent in a clinical trial was validated. J Clin Epidemiol. 2006 Jun;59 (6) :608-14. Epub 2006 Mar 24. PMID: 16713523


Sun N, Carroll RJ and Zhao H: Bayesian error analysis model for reconstructing transcriptional regulatory networks. Proc Natl Acad Sci U S A. 2006 May 23;103 (21) :7988-93. Epub 2006 May 15. PMID: 16702552


Gelernter J, Panhuysen C, Wilcox M, Hesselbrock V, Rounsaville B, Poling J, Weiss R, Sonne S, Zhao H, Farrer L and Kranzler HR: Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet. 2006 May;78 (5) :759-69. Epub 2006 Mar 16. PMID: 16642432


Fried TR, Byers AL, Gallo WT, Van Ness PH, Towle VR, O'Leary JR and Dubin JA: Prospective study of health status preferences and changes in preferences over time in older adults. Arch Intern Med. 2006 Apr 24;166 (8) :890-5. PMID: 16636215


Belcher VN, Fried TR, Agostini JV and Tinetti ME: Views of older adults on patient participation in medication-related decision making. J Gen Intern Med. 2006 Apr;21 (4) :298-303. PMID: 16686804


You X, Pan M, Gao W, Shiah HS, Tao J, Zhang D, Koumpouras F, Wang S, Zhao H, Madri JA, Baker D, Cheng YC and Yin Z: Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response. Arthritis Rheum. 2006 Mar;54 (3) :877-86. PMID: 16508970


Zeiss CJ, Allore HG, Towle V and Tao W: CNTF induces dose-dependent alterations in retinal morphology in normal and rcd-1 canine retina. Exp Eye Res. 2006 Mar;82 (3) :395-404. Epub 2005 Sep 6. PMID: 16143329


Levy BR, Slade MD and Gill TM: Hearing decline predicted by elders' stereotypes. J Gerontol B Psychol Sci Soc Sci. 2006 Mar;61 (2) :P82-7. PMID: 16497958


Gill TM, Gahbauer EA, Allore HG and Han L: Transitions between frailty states among community-living older persons. Arch Intern Med. 2006 Feb 27;166 (4) :418-23. PMID: 16505261


Yu W, Wu B, Lin N, Stone K, Williams K and Zhao H: Detecting and aligning peaks in mass spectrometry data with applications to MALDI. Comput Biol Chem. 2006 Feb;30 (1) :27-38. Epub 2005 Nov 17. PMID: 16298163


Gill TM, Allore HG, Hardy SE and Guo Z: The dynamic nature of mobility disability in older persons. J Am Geriatr Soc. 2006 Feb;54 (2) :248-54. PMID: 16460375


Chou WC, Tinetti ME, King MB, Irwin K and Fortinsky RH: Perceptions of physicians on the barriers and facilitators to integrating fall risk evaluation and management into practice. J Gen Intern Med. 2006 Feb;21 (2) :117-22. Epub 2005 Dec 7. PMID: 16336618


Fried TR, Bradley EH and O'Leary J: Changes in prognostic awareness among seriously ill older persons and their caregivers. J Palliat Med. 2006 Feb;9 (1) :61-9. PMID: 16430346


Concato J, Wells CK, Horwitz RI, Penson D, Fincke G, Berlowitz DR, Froehlich G, Blake D, Vickers MA, Gehr GA, Raheb NH, Sullivan G and Peduzzi P: The effectiveness of screening for prostate cancer: a nested case-control study. Arch Intern Med. 2006 Jan 9;166 (1) :38-43. PMID: 16401808


Guarino P, Elbourne D, Carpenter J and Peduzzi P: Consumer involvement in consent document development: a multicenter cluster randomized trial to assess study participants' understanding. Clin Trials. 2006;3 (1) :19-30. PMID: 16539087


Pisani MA, Araujo KL, Van Ness PH, Zhang Y, Ely EW and Inouye SK: A research algorithm to improve detection of delirium in the intensive care unit. Crit Care. 2006;10 (4) :R121. PMID: 16919169


Walke LM, Byers AL, McCorkle R and Fried TR: Symptom assessment in community-dwelling older adults with advanced chronic disease. J Pain Symptom Manage. 2006 Jan;31 (1) :31-7. PMID: 16442480


Yu W, Wu B, Liu J, Li X, Stone K, Williams KR and Zhao H: MALDI-MS data analysis for disease biomarker discovery. Methods Mol Biol. 2006;328 :199-216. PMID: 16785651


Enerson BE, Lin A, Lu B, Zhao H, Lawton MP and Floyd E: Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression. Toxicol Pathol. 2006;34 (1) :27-32. PMID: 16507541


van Duin D, Medzhitov R and Shaw AC: Triggering TLR signaling in vaccination. Trends Immunol. 2006 Jan;27 (1) :49-55. Epub 2005 Nov 23. PMID: 16310411

Huang S, Wang S, Liu N, Chen L, Oh C and Zhao H: Whole-genome association analysis to identify markers associated with recombination rates using single-nucleotide polymorphisms and microsatellites. BMC Genet. 2005 Dec 30;6 Suppl 1 :S51. Epub 2005 Dec 30. PMID: 16451663


Liu N, Chen L, Wang S, Oh C and Zhao H: Comparison of single-nucleotide polymorphisms and microsatellites in inference of population structure. BMC Genet. 2005 Dec 30;6 Suppl 1 :S26. Epub 2005 Dec 30. PMID: 16451635


Chen L, Liu N, Wang S, Oh C, Carriero NJ and Zhao H: Whole-genome association studies on alcoholism comparing different phenotypes using single-nucleotide polymorphisms and microsatellites. BMC Genet. 2005 Dec 30;6 Suppl 1 :S130. Epub 2005 Dec 30. PMID: 16451589


Oh C, Wang S, Liu N, Chen L and Zhao H: A Bayesian genome screening of maximum number of drinks as an alcoholism phenotype with the new Haseman-Elston method. BMC Genet. 2005 Dec 30;6 Suppl 1 :S116. Epub 2005 Dec 30. PMID: 16451573


Gill TM and Gahbauer EA: Overestimation of chronic disability among elderly persons. Arch Intern Med. 2005 Dec 12-26;165 (22) :2625-30. PMID: 16344420


Barry LC, Gill TM, Kerns RD and Reid MC: Identification of pain-reduction strategies used by community-dwelling older persons. J Gerontol A Biol Sci Med Sci. 2005 Dec;60 (12) :1569-75. PMID: 16424290


Cherlin E, Fried T, Prigerson HG, Schulman-Green D, Johnson-Hurzeler R and Bradley EH: Communication between physicians and family caregivers about care at the end of life: when do discussions occur and what is said? J Palliat Med. 2005 Dec;8 (6) :1176-85. PMID: 16351531


Chen L and Zhao H: Negative correlation between compositional symmetries and local recombination rates. Bioinformatics. 2005 Nov 1;21 (21) :3951-8. Epub 2005 Aug 30. PMID: 16131519


Juthani-Mehta M, Drickamer MA, Towle V, Zhang Y, Tinetti ME and Quagliarello VJ: Nursing home practitioner survey of diagnostic criteria for urinary tract infections. J Am Geriatr Soc. 2005 Nov;53 (11) :1986-90. PMID: 16274383


Huang T, Wu B, Lizardi P and Zhao H: Detection of DNA copy number alterations using penalized least squares regression. Bioinformatics. 2005 Oct 15;21 (20) :3811-7. Epub 2005 Aug 30. PMID: 16131523


Yang BZ, Zhao H, Kranzler HR and Gelernter J: Characterization of a likelihood based method and effects of markers informativeness in evaluation of admixture and population group assignment. BMC Genet. 2005 Oct 14;6 :50. Epub 2005 Oct 14. PMID: 16225681


Goldstein NE, Concato J, Bradley EH, O'Leary JR and Fried TR: Doctor-patient communication about prognosis: the influence of race and financial status. J Palliat Med. 2005 Oct;8 (5) :998-1004. PMID: 16238512


Ma L, Chen C, Liu X, Jiao Y, Su N, Li L, Wang X, Cao M, Sun N, Zhang X, Bao J, Li J, Pedersen S, Bolund L, Zhao H, Yuan L, Wong GK, Wang J, Deng XW and Wang J: A microarray analysis of the rice transcriptome and its comparison to Arabidopsis. Genome Res. 2005 Sep;15 (9) :1274-83. PMID: 16140994


Naik AD and Gill TM: Underutilization of environmental adaptations for bathing in community-living older persons. J Am Geriatr Soc. 2005 Sep;53 (9) :1497-503. PMID: 16137278


Liu Y, Liu N and Zhao H: Inferring protein-protein interactions through high-throughput interaction data from diverse organisms. Bioinformatics. 2005 Aug 1;21 (15) :3279-85. Epub 2005 May 19. PMID: 15905281


Gill TM, Allore H, Hardy SE, Holford TR and Han L: Estimates of active and disabled life expectancy based on different assessment intervals. J Gerontol A Biol Sci Med Sci. 2005 Aug;60 (8) :1013-6. PMID: 16127105


Zou G and Zhao H: Family-based association tests for different family structures using pooled DNA. Ann Hum Genet. 2005 Jul;69 (Pt 4) :429-42. PMID: 15996171


Gulcicek EE, Colangelo CM, McMurray W, Stone K, Williams K, Wu T, Zhao H, Spratt H, Kurosky A and Wu B: Proteomics and the analysis of proteomic data: an overview of current protein-profiling technologies. Curr Protoc Bioinformatics. 2005 Jul;Chapter 13 :Unit 13.1. PMID: 18428746


Jiao Y, Jia P, Wang X, Su N, Yu S, Zhang D, Ma L, Feng Q, Jin Z, Li L, Xue Y, Cheng Z, Zhao H, Han B and Deng XW: A tiling microarray expression analysis of rice chromosome 4 suggests a chromosome-level regulation of transcription. Plant Cell. 2005 Jun;17 (6) :1641-57. Epub 2005 Apr 29. PMID: 15863518


Mor G, Visintin I, Lai Y, Zhao H, Schwartz P, Rutherford T, Yue L, Bray-Ward P and Ward DC: Serum protein markers for early detection of ovarian cancer. Proc Natl Acad Sci U S A. 2005 May 24;102 (21) :7677-82. Epub 2005 May 12. PMID: 15890779


Yang BZ, Zhao H, Kranzler HR and Gelernter J: Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE. Genet Epidemiol. 2005 May;28 (4) :302-12. PMID: 15782414


Ma L, Sun N, Liu X, Jiao Y, Zhao H and Deng XW: Organ-specific expression of Arabidopsis genome during development. Plant Physiol. 2005 May;138 (1) :80-91. PMID: 15888681


Holford M, Li N, Nadkarni P and Zhao H: VitaPad: visualization tools for the analysis of pathway data. Bioinformatics. 2005 Apr 15;21 (8) :1596-602. Epub 2004 Nov 25. PMID: 15564306


Tinetti ME, Allore H, Araujo KL and Seeman T: Modifiable impairments predict progressive disability among older persons. J Aging Health. 2005 Apr;17 (2) :239-56. PMID: 15750053


Baker DI, King MB, Fortinsky RH, Graff LG 4th, Gottschalk M, Acampora D, Preston J, Brown CJ and Tinetti ME: Dissemination of an evidence-based multicomponent fall risk-assessment and -management strategy throughout a geographic area. J Am Geriatr Soc. 2005 Apr;53 (4) :675-80. PMID: 15817016


Chen L and Zhao H: Gene expression analysis reveals that histone deacetylation sites may serve as partitions of chromatin gene expression domains. BMC Genomics. 2005 Mar 23;6 :44. Epub 2005 Mar 23. PMID: 15788094


Zhang SS, Xu X, Li J, Liu MG, Zhao H, Soares MB, Barnstable CJ and Fu XY: Comprehensive in silico functional specification of mouse retina transcripts. BMC Genomics. 2005 Mar 18;6 :40. Epub 2005 Mar 18. PMID: 15777472


Hardy SE, Dubin JA, Holford TR and Gill TM: Transitions between states of disability and independence among older persons. Am J Epidemiol. 2005 Mar 15;161 (6) :575-84. PMID: 15746474


Kernan WN, Quagliarello V and Green ML: Student faculty rounds: a peer-mediated learning activity for internal medicine clerkships. Med Teach. 2005 Mar;27 (2) :140-4. PMID: 16019334


Kernan WN, Viscoli CM, Brass LM, Gill TM, Sarrel PM and Horwitz RI: Decline in physical performance among women with a recent transient ischemic attack or ischemic stroke: opportunities for functional preservation a report of the Women's Estrogen Stroke Trial. Stroke. 2005 Mar;36 (3) :630-4. Epub 2005 Jan 27. PMID: 15677573


Allore H, Tinetti ME, Araujo KL, Hardy S and Peduzzi P: A case study found that a regression tree outperformed multiple linear regression in predicting the relationship between impairments and Social and Productive Activities scores. J Clin Epidemiol. 2005 Feb;58 (2) :154-61. PMID: 15680749


Chen JH, Gill TM and Prigerson HG: Health behaviors associated with better quality of life for older bereaved persons. J Palliat Med. 2005 Feb;8 (1) :96-106. PMID: 15662178


Hardy SE and Gill TM: Factors associated with recovery of independence among newly disabled older persons. Arch Intern Med. 2005 Jan 10;165 (1) :106-12. PMID: 15642885


Quagliarello V, Ginter S, Han L, Van Ness P, Allore H and Tinetti M: Modifiable risk factors for nursing home-acquired pneumonia. Clin Infect Dis. 2005 Jan 1;40 (1) :1-6. Epub 2004 Dec 1. PMID: 15614684


Allore HG, Tinetti ME, Gill TM and Peduzzi PN: Experimental designs for multicomponent interventions among persons with multifactorial geriatric syndromes. Clin Trials. 2005;2 (1) :13-21. PMID: 16279575


Fried TR, Bradley EH, O'Leary JR and Byers AL: Unmet desire for caregiver-patient communication and increased caregiver burden. J Am Geriatr Soc. 2005 Jan;53 (1) :59-65. PMID: 15667377


Carriero N, Osier MV, Cheung KH, Miller PL, Gerstein M, Zhao H, Wu B, Rifkin S, Chang J, Zhang H, White K, Williams K and Schultz M: A high productivity/low maintenance approach to high-performance computation for biomedicine: four case studies. J Am Med Inform Assoc. 2005 Jan-Feb;12 (1) :90-8. Epub 2004 Oct 18. PMID: 15492032

Tinetti ME, Bogardus ST Jr and Agostini JV: Potential pitfalls of disease-specific guidelines for patients with multiple conditions. N Engl J Med. 2004 Dec 30;351 (27) :2870-4. PMID: 15625341


Liu N, Sawyer SL, Mukherjee N, Pakstis AJ, Kidd JR, Kidd KK, Brookes AJ and Zhao H: Haplotype block structures show significant variation among populations. Genet Epidemiol. 2004 Dec;27 (4) :385-400. PMID: 15389924


Walke LM, Gallo WT, Tinetti ME and Fried TR: The burden of symptoms among community-dwelling older persons with advanced chronic disease. Arch Intern Med. 2004 Nov 22;164 (21) :2321-4. PMID: 15557410


Lai Y, Wu B, Chen L and Zhao H: A statistical method for identifying differential gene-gene co-expression patterns. Bioinformatics. 2004 Nov 22;20 (17) :3146-55. Epub 2004 Jul 1. PMID: 15231528


Wilson FH, Hariri A, Farhi A, Zhao H, Petersen KF, Toka HR, Nelson-Williams C, Raja KM, Kashgarian M, Shulman GI, Scheinman SJ and Lifton RP: A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science. 2004 Nov 12;306 (5699) :1190-4. Epub 2004 Oct 21. PMID: 15498972


Gill TM, Allore HG, Holford TR and Guo Z: Hospitalization, restricted activity, and the development of disability among older persons. JAMA. 2004 Nov 3;292 (17) :2115-24. PMID: 15523072


Liu Y and Zhao H: A computational approach for ordering signal transduction pathway components from genomics and proteomics Data. BMC Bioinformatics. 2004 Oct 25;5 :158. Epub 2004 Oct 25. PMID: 15504238


Gill TM, Allore H, Holford TR and Guo Z: The development of insidious disability in activities of daily living among community-living older persons. Am J Med. 2004 Oct 1;117 (7) :484-91. PMID: 15464705


Agostini JV, Han L and Tinetti ME: The relationship between number of medications and weight loss or impaired balance in older adults. J Am Geriatr Soc. 2004 Oct;52 (10) :1719-23. PMID: 15450051


Rosenbaum JR, Bravata DM, Concato J, Brass LM, Kim N and Fried TR: Informed consent for thrombolytic therapy for patients with acute ischemic stroke treated in routine clinical practice. Stroke. 2004 Sep;35 (9) :e353-5. Epub 2004 Jul 8. PMID: 15243145


Hoek K, Rimm DL, Williams KR, Zhao H, Ariyan S, Lin A, Kluger HM, Berger AJ, Cheng E, Trombetta ES, Wu T, Niinobe M, Yoshikawa K, Hannigan GE and Halaban R: Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res. 2004 Aug 1;64 (15) :5270-82. PMID: 15289333


Levy BR, Kasl SV and Gill TM: Image of aging scale. Percept Mot Skills. 2004 Aug;99 (1) :208-10. PMID: 15446647


Gill TM, Baker DI, Gottschalk M, Peduzzi PN, Allore H and Van Ness PH: A prehabilitation program for the prevention of functional decline: effect on higher-level physical function. Arch Phys Med Rehabil. 2004 Jul;85 (7) :1043-9. PMID: 15241748


Gill TM, Allore H and Guo Z: The deleterious effects of bed rest among community-living older persons. J Gerontol A Biol Sci Med Sci. 2004 Jul;59 (7) :755-61. PMID: 15304541


Marathe R, Guan Z, Anandalakshmi R, Zhao H and Dinesh-Kumar SP: Study of Arabidopsis thaliana resistome in response to cucumber mosaic virus infection using whole genome microarray. Plant Mol Biol. 2004 Jul;55 (4) :501-20. PMID: 15604696


Zou G and Zhao H: The estimation of sibling genetic risk parameters revisited. Genet Epidemiol. 2004 May;26 (4) :286-93. PMID: 15095388


Gill TM, McDermott MM, Ibrahim SA, Petersen LA and Doebbeling BN: Getting funded. Career development awards for aspiring clinical investigators. J Gen Intern Med. 2004 May;19 (5 Pt 1) :472-8. PMID: 15109347


Fraenkel L, Wittink DR, Concato J and Fried T: Informed choice and the widespread use of antiinflammatory drugs. Arthritis Rheum. 2004 Apr 15;51 (2) :210-4. PMID: 15077261


Hardy SE and Gill TM: Recovery from disability among community-dwelling older persons. JAMA. 2004 Apr 7;291 (13) :1596-602. PMID: 15069047


Goldstein NE, Concato J, Fried TR, Kasl SV, Johnson-Hurzeler R and Bradley EH: Factors associated with caregiver burden among caregivers of terminally ill patients with cancer. J Palliat Care. 2004 Spring;20 (1) :38-43. PMID: 15132075


Juthani-Mehta M and Quagliarello VJ: Prognostic scoring systems for infectious diseases: their applicability to the care of older adults. Clin Infect Dis. 2004 Mar 1;38 (5) :692-6. Epub 2004 Feb 17. PMID: 14986254


Fraenkel L, Wittink DR, Concato J and Fried T: Are preferences for cyclooxygenase-2 inhibitors influenced by the certainty effect? J Rheumatol. 2004 Mar;31 (3) :591-3. PMID: 14994409


Sun N and Zhao H: Genomic approaches in dissecting complex biological pathways. Pharmacogenomics. 2004 Mar;5 (2) :163-79. PMID: 15016608


Gao Y, Li J, Strickland E, Hua S, Zhao H, Chen Z, Qu L and Deng XW: An arabidopsis promoter microarray and its initial usage in the identification of HY5 binding targets in vitro. Plant Mol Biol. 2004 Mar;54 (5) :683-99. PMID: 15356388


Goh CS, Lan N, Douglas SM, Wu B, Echols N, Smith A, Milburn D, Montelione GT, Zhao H and Gerstein M: Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis. J Mol Biol. 2004 Feb 6;336 (1) :115-30. PMID: 14741208


Tinetti ME and Fried T: The end of the disease era. Am J Med. 2004 Feb 1;116 (3) :179-85. PMID: 14749162


Hardy SE, Concato J and Gill TM: Resilience of community-dwelling older persons. J Am Geriatr Soc. 2004 Feb;52 (2) :257-62. PMID: 14728637


Xia Y, Yu H, Jansen R, Seringhaus M, Baxter S, Greenbaum D, Zhao H and Gerstein M: Analyzing cellular biochemistry in terms of molecular networks. Annu Rev Biochem. 2004;73 :1051-87. PMID: 15189167


Zou G and Zhao H: The impacts of errors in individual genotyping and DNA pooling on association studies. Genet Epidemiol. 2004 Jan;26 (1) :1-10. PMID: 14691952


Van Ness PH, Davis WR and Johnson BD: Socioeconomic marginality and health services utilization among Central Harlem substance users. Subst Use Misuse. 2004 Jan;39 (1) :61-85. PMID: 15002944

Vikram HR, Buenconsejo J, Hasbun R and Quagliarello VJ: Impact of valve surgery on 6-month mortality in adults with complicated, left-sided native valve endocarditis: a propensity analysis. JAMA. 2003 Dec 24;290 (24) :3207-14. PMID: 14693873


Gill TM and Kurland BF: Prognostic effect of prior disability episodes among nondisabled community-living older persons. Am J Epidemiol. 2003 Dec 1;158 (11) :1090-6. PMID: 14630605


Jiao Y, Yang H, Ma L, Sun N, Yu H, Liu T, Gao Y, Gu H, Chen Z, Wada M, Gerstein M, Zhao H, Qu LJ and Deng XW: A genome-wide analysis of blue-light regulation of Arabidopsis transcription factor gene expression during seedling development. Plant Physiol. 2003 Dec;133 (4) :1480-93. Epub 2003 Nov 6. PMID: 14605227


Pan D, Sun N, Cheung KH, Guan Z, Ma L, Holford M, Deng X and Zhao H: PathMAPA: a tool for displaying gene expression and performing statistical tests on metabolic pathways at multiple levels for Arabidopsis. BMC Bioinformatics. 2003 Nov 7;4 :56. Epub 2003 Nov 7. PMID: 14604444


Wang S and Zhao H: Sample size needed to detect gene-gene interactions using association designs. Am J Epidemiol. 2003 Nov 1;158 (9) :899-914. PMID: 14585768


Sun N, Ma L, Pan D, Zhao H and Deng XW: Evaluation of light regulatory potential of Calvin cycle steps based on large-scale gene expression profiling data. Plant Mol Biol. 2003 Nov;53 (4) :467-78. PMID: 15010613


Zheng L, Wang S, Romans P, Zhao H, Luna C and Benedict MQ: Quantitative trait loci in Anopheles gambiae controlling the encapsulation response against Plasmodium cynomolgi Ceylon. BMC Genet. 2003 Oct 24;4 :16. Epub 2003 Oct 24. PMID: 14577840


Fried TR, Bradley EH and O'Leary J: Prognosis communication in serious illness: perceptions of older patients, caregivers, and clinicians. J Am Geriatr Soc. 2003 Oct;51 (10) :1398-403. PMID: 14511159


Fried TR, Bradley EH and Towle VR: Valuing the outcomes of treatment: do patients and their caregivers agree? Arch Intern Med. 2003 Sep 22;163 (17) :2073-8. PMID: 14504121


Wu B, Abbott T, Fishman D, McMurray W, Mor G, Stone K, Ward D, Williams K and Zhao H: Comparison of statistical methods for classification of ovarian cancer using mass spectrometry data. Bioinformatics. 2003 Sep 1;19 (13) :1636-43. PMID: 12967959


Garcia-Rostan G, Zhao H, Camp RL, Pollan M, Herrero A, Pardo J, Wu R, Carcangiu ML, Costa J and Tallini G: ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer. J Clin Oncol. 2003 Sep 1;21 (17) :3226-35. PMID: 12947056


Sun LV, Chen L, Greil F, Negre N, Li TR, Cavalli G, Zhao H, Van Steensel B and White KP: Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila. Proc Natl Acad Sci U S A. 2003 Aug 5;100 (16) :9428-33. Epub 2003 Jul 22. PMID: 12876199


Luo X, Kranzler HR, Zhao H and Gelernter J: Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans. Am J Med Genet B Neuropsychiatr Genet. 2003 Jul 1;120B (1) :97-108. PMID: 12815747


Zou G, Pan D and Zhao H: Genotyping error detection through tightly linked markers. Genetics. 2003 Jul;164 (3) :1161-73. PMID: 12871922


Wikonkal NM, Remenyik E, Knezevic D, Zhang W, Liu M, Zhao H, Berton TR, Johnson DG and Brash DE: Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice. Nat Cell Biol. 2003 Jul;5 (7) :655-60. PMID: 12833065


Gill TM, Allore H and Guo Z: Restricted activity and functional decline among community-living older persons. Arch Intern Med. 2003 Jun 9;163 (11) :1317-22. PMID: 12796067


Byers AL, Allore H, Gill TM and Peduzzi PN: Application of negative binomial modeling for discrete outcomes: a case study in aging research. J Clin Epidemiol. 2003 Jun;56 (6) :559-64. PMID: 12873651


Bogardus ST Jr, Desai MM, Williams CS, Leo-Summers L, Acampora D and Inouye SK: The effects of a targeted multicomponent delirium intervention on postdischarge outcomes for hospitalized older adults. Am J Med. 2003 Apr 1;114 (5) :383-90. PMID: 12714128


Fried TR and Bradley EH: What matters to seriously ill older persons making end-of-life treatment decisions?: A qualitative study. J Palliat Med. 2003 Apr;6 (2) :237-44. PMID: 12854940


Gill TM, Baker DI, Gottschalk M, Gahbauer EA, Charpentier PA, de Regt PT and Wallace SJ: A prehabilitation program for physically frail community-living older persons. Arch Phys Med Rehabil. 2003 Mar;84 (3) :394-404. PMID: 12638108


Ma L, Zhao H and Deng XW: Analysis of the mutational effects of the COP/DET/FUS loci on genome expression profiles reveals their overlapping yet not identical roles in regulating Arabidopsis seedling development. Development. 2003 Mar;130 (5) :969-81. PMID: 12538522


Zhao H, Pfeiffer R and Gail MH: Haplotype analysis in population genetics and association studies. Pharmacogenomics. 2003 Mar;4 (2) :171-8. PMID: 12605551


Tinetti ME: Clinical practice. Preventing falls in elderly persons. N Engl J Med. 2003 Jan 2;348 (1) :42-9. PMID: 12510042


Wang S, Kidd KK and Zhao H: On the use of DNA pooling to estimate haplotype frequencies. Genet Epidemiol. 2003 Jan;24 (1) :74-82. PMID: 12508258


Zhang S, Zhu X and Zhao H: On a semiparametric test to detect associations between quantitative traits and candidate genes using unrelated individuals. Genet Epidemiol. 2003 Jan;24 (1) :44-56. PMID: 12508255


Zou G and Zhao H: Haplotype frequency estimation in the presence of genotyping errors. Hum Hered. 2003;56 (1-3) :131-8. PMID: 14614247


Van Ness PH, Kasl SV and Jones BA: Religion, race, and breast cancer survival. Int J Psychiatry Med. 2003;33 (4) :357-75. PMID: 15152786


Gill TM and Kurland B: The burden and patterns of disability in activities of daily living among community-living older persons. J Gerontol A Biol Sci Med Sci. 2003 Jan;58 (1) :70-5. PMID: 12560415


Van Ness PH and Kasl SV: Religion and cognitive dysfunction in an elderly cohort. J Gerontol B Psychol Sci Soc Sci. 2003 Jan;58 (1) :S21-9. PMID: 12496305

Wang H, Ma L, Habashi J, Li J, Zhao H and Deng XW: Analysis of far-red light-regulated genome expression profiles of phytochrome A pathway mutants in Arabidopsis. Plant J. 2002 Dec;32 (5) :723-33. PMID: 12472688


Mani A, Meraji SM, Houshyar R, Radhakrishnan J, Mani A, Ahangar M, Rezaie TM, Taghavinejad MA, Broumand B, Zhao H, Nelson-Williams C and Lifton RP: Finding genetic contributions to sporadic disease: a recessive locus at 12q24 commonly contributes to patent ductus arteriosus. Proc Natl Acad Sci U S A. 2002 Nov 12;99 (23) :15054-9. Epub 2002 Oct 30. PMID: 12409608


McGloin JM: Dying in Connecticut--the facts. Conn Med. 2002 Nov;66 (11) :665-9. PMID: 12476508


Hardy SE, Concato J and Gill TM: Stressful life events among community-living older persons. J Gen Intern Med. 2002 Nov;17 (11) :832-8. PMID: 12406354


Fried TR, Bradley EH and Towle VR: Assessment of patient preferences: integrating treatments and outcomes. J Gerontol B Psychol Sci Soc Sci. 2002 Nov;57 (6) :S348-54. PMID: 12426443


Gill TM, Baker DI, Gottschalk M, Peduzzi PN, Allore H and Byers A: A program to prevent functional decline in physically frail, elderly persons who live at home. N Engl J Med. 2002 Oct 3;347 (14) :1068-74. PMID: 12362007


Ma L, Gao Y, Qu L, Chen Z, Li J, Zhao H and Deng XW: Genomic evidence for COP1 as a repressor of light-regulated gene expression and development in Arabidopsis. Plant Cell. 2002 Oct;14 (10) :2383-98. PMID: 12368493


Gill TM, Hardy SE and Williams CS: Underestimation of disability in community-living older persons. J Am Geriatr Soc. 2002 Sep;50 (9) :1492-7. PMID: 12383145


Wu G, Tian X, Nishimura S, Markowitz GS, D'Agati V, Park JH, Yao L, Li L, Geng L, Zhao H, Edelmann W and Somlo S: Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease. Hum Mol Genet. 2002 Aug 1;11 (16) :1845-54. PMID: 12140187


Van Ness PH and Larson DB: Religion, senescence, and mental health: the end of life is not the end of hope. Am J Geriatr Psychiatry. 2002 Jul-Aug;10 (4) :386-97. PMID: 12095898


Gill TM: Geriatric medicine: it's more than caring for old people. Am J Med. 2002 Jul;113 (1) :85-90. PMID: 12106630


Thomas KE, Hasbun R, Jekel J and Quagliarello VJ: The diagnostic accuracy of Kernig's sign, Brudzinski's sign, and nuchal rigidity in adults with suspected meningitis. Clin Infect Dis. 2002 Jul 1;35 (1) :46-52. Epub 2002 Jun 5. PMID: 12060874


Fried TR, Bradley EH, Towle VR and Allore H: Understanding the treatment preferences of seriously ill patients. N Engl J Med. 2002 Apr 4;346 (14) :1061-6. PMID: 11932474


Murphy SL, Williams CS and Gill TM: Characteristics associated with fear of falling and activity restriction in community-living older persons. J Am Geriatr Soc. 2002 Mar;50 (3) :516-20. PMID: 11943049


Vikram HR and Quagliarello VJ: Diagnosis and management of empyema. Curr Clin Top Infect Dis. 2002;22 :196-213. PMID: 12520655


Zhang S and Zhao H: Linkage disequilibrium mapping with genotype data. Genet Epidemiol. 2002 Jan;22 (1) :66-77. PMID: 11754474


Erickson SE, Fried TR, Cherlin E, Johnson-Hurzeler R, Horwitz SM and Bradley EH: The effect of inpatient hospice units on hospice use post-admission. Home Health Care Serv Q. 2002;21 (2) :73-83. PMID: 12363002


Van Ness PH, Kasl SV and Jones BA: Are Religious Women More Likely to Have Breast Cancer Screening? J Relig Health. 2002 Winter;41 (4) :333-346. PMID: 23293394


Zhang S, Zhang K, Li J and Zhao H: On a family-based haplotype pattern mining method for linkage disequilibrium mapping. Pac Symp Biocomput. 2002; :100-11. PMID: 11928467


Cheung KH, White K, Hager J, Gerstein M, Reinke V, Nelson K, Masiar P, Srivastava R, Li Y, Li J, Zhao H, Li J, Allison DB, Snyder M, Miller P and Williams K: YMD: a microarray database for large-scale gene expression analysis. Proc AMIA Symp. 2002; :140-4. PMID: 12463803