Pepper Center Publications

Fried T, Zenoni M, Iannone L: A Dyadic Perspective on Engagement in Advance Care Planning. J Am Geriatr Soc. 2016 Dec 2; 2016 Dec 2. PMID: 27910091

Trentalange M, Bielawski M, Murphy TE, Lessard K, Brandt C, Bean-Mayberry B, Maisel NC, Wright SM, Allore H, Skanderson M, Reyes-Harvey E, Gaetano V, Haskell S, Bastian LA: Patient Perception of Enough Time Spent With Provider Is a Mechanism for Improving Women Veterans' Experiences With VA Outpatient Health Care. Eval Health Prof. 2016 Dec; 2016 Feb 22. PMID: 26908572

Knauert M, Jeon S, Murphy TE, Yaggi HK, Pisani MA, Redeker NS: Comparing average levels and peak occurrence of overnight sound in the medical intensive care unit on A-weighted and C-weighted decibel scales. J Crit Care. 2016 Dec; 2016 Jun 22. PMID: 27546739

Cohen AB, Knobf MT, Fried TR: Avoiding Hospitalizations From Nursing Homes for Potentially Burdensome Care: Results of a Qualitative Study. JAMA Intern Med. 2016 Nov 28; 2016 Nov 28. PMID: 27893891

Murphy TE, Chaudhry SI: Benefit of Warfarin in Older Persons with Atrial Fibrillation. J Am Geriatr Soc. 2016 Nov 12; 2016 Nov 12. PMID: 27858955

Massarotti EM, Allore HG, Costenbader K: Interferon-Targeted Therapy for SLE: Are the Trials on Target? Arthritis Rheumatol. 2016 Nov 11; 2016 Nov 11. PMID: 27860434

Juthani-Mehta M, Van Ness PH, Bianco L, Rink A, Rubeck S, Ginter S, Argraves S, Charpentier P, Acampora D, Trentalange M, Quagliarello V, Peduzzi P: Effect of Cranberry Capsules on Bacteriuria Plus Pyuria Among Older Women in Nursing Homes: A Randomized Clinical Trial. JAMA. 2016 Nov 8. PMID: 27787564

Smith-Vikos T, Liu Z, Parsons C, Gorospe M, Ferrucci L, Gill TM, Slack FJ: A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of Aging (BLSA). Aging (Albany NY). 2016 Nov 7; 2016 Nov 7. PMID: 27824314

Lindow JC, Wunder EA Jr, Popper SJ, Min JN, Mannam P, Srivastava A, Yao Y, Hacker KP, Raddassi K, Lee PJ, Montgomery RR, Shaw AC, Hagan JE, Araújo GC, Nery N Jr, Relman DA, Kim CC, Reis MG, Ko AI: Cathelicidin Insufficiency in Patients with Fatal Leptospirosis. PLoS Pathog. 2016 Nov 3; 2016 Nov 3. PMID: 27812211

Riffin C, Fried T, Pillemer K: Impact of Pain on Family Members and Caregivers of Geriatric Patients. Clin Geriatr Med. 2016 Nov; 2016 Aug 4. PMID: 27741962

Cooper Z, Rogers SO Jr, Ngo L, Guess J, Schmitt E, Jones RN, Ayres DK, Walston JD, Gill TM, Gleason LJ, Inouye SK, Marcantonio ER: Comparison of Frailty Measures as Predictors of Outcomes After Orthopedic Surgery. J Am Geriatr Soc. 2016 Nov 1; 2016 Nov 1. PMID: 27801939

Ó Hartaigh B, Lovato LC, Pahor M, Buford TW, Dodson JA, Forman DE, Buman MP, Demons JL, Santanasto AJ, Liu C, Miller ME, McDermott MM, Gill TM, LIFE Study Group.: Effect of a Long-Term Physical Activity Intervention on Resting Pulse Rate in Older Persons: Results from the Lifestyle Interventions and Independence for Elders Study. J Am Geriatr Soc. 2016 Oct 27; 2016 Oct 27. PMID: 27787876

Wang Q, Polimanti R, Kranzler HR, Farrer LA, Zhao H, Gelernter J: Genetic factor common to schizophrenia and HIV infection is associated with risky sexual behavior: antagonistic vs. synergistic pleiotropic SNPs enriched for distinctly different biological functions. Hum Genet. 2016 Oct 17; 2016 Oct 17. PMID: 27752767

Zhu R, Zhao YQ, Chen G, Ma S, Zhao H: Greedy outcome weighted tree learning of optimal personalized treatment rules. Biometrics. 2016 Oct 4; 2016 Oct 4. PMID: 27704531

Zhu R, Zhao Q, Zhao H, Ma S: Integrating multidimensional omics data for cancer outcome. Biostatistics. 2016 Oct; 2016 Mar 14. PMID: 26980320

Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Evelyn Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, Schiff ER, Gusev A, Schumm LP, Bowen BM, Sharma Y, Ning K, Remark R, Gnjatic S, Legnani P, George J, Sands BE, Stempak JM, Datta LW, Lipka S, Katz S, Cheifetz AS, Barzilai N, Pontikos N, Abraham C, Dubinsky MJ, Targan S, Taylor K, Rotter JI, Scherl EJ, Desnick RJ, Abreu MT, Zhao H, Atzmon G, Pe'er I, Kugathasan S, Hakonarson H, McCauley JL, Lencz T, Darvasi A, Plagnol V, Silverberg MS, Muise AM, Brant SR, Daly MJ, Segal AW, Duerr RH, Merad M, McGovern DP, Peter I, Cho JH: A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF. Gastroenterology. 2016 Oct; 2016 Jul 1. PMID: 27377463

Coylewright M, Palmer R, O'Neill ES, Robb JF, Fried TR: Patient-defined goals for the treatment of severe aortic stenosis: a qualitative analysis. Health Expect. 2016 Oct; 2015 Aug 14. PMID: 26275070

Miner B, Tinetti ME, Van Ness PH, Han L, Leo-Summers L, Newman AB, Lee PJ, Vaz Fragoso CA: Dyspnea in Community-Dwelling Older Persons: A Multifactorial Geriatric Health Condition. J Am Geriatr Soc. 2016 Oct; 2016 Aug 22. PMID: 27549914

Gill TM, Guralnik JM, Pahor M, Church T, Fielding RA, King AC, Marsh AP, Newman AB, Pellegrini CA, Chen SH, Allore HG, Miller ME, LIFE Study Investigators.: Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized, Controlled Trial. Ann Intern Med. 2016 Sep 27; 2016 Sep 27. PMID: 27669457

Lipska KJ, Yao X, Herrin J, McCoy RG, Ross JS, Steinman MA, Inzucchi SE, Gill TM, Krumholz HM, Shah ND: Trends in Drug Utilization, Glycemic Control, and Rates of Severe Hypoglycemia, 2006-2013. Diabetes Care. 2016 Sep 22; 2016 Sep 22. PMID: 27659408

Polimanti R, Wang Q, Meda SA, Patel KT, Pearlson GD, Zhao H, Farrer LA, Kranzler HR, Gelernter J: The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene. Neuropsychopharmacology. 2016 Sep 14; 2016 Sep 14. PMID: 27531626

Dong K, Zhao H, Tong T, Wan X: NBLDA: negative binomial linear discriminant analysis for RNA-Seq data. BMC Bioinformatics. 2016 Sep 13; 2016 Sep 13. PMID: 27623864

Timberlake AT, Choi J, Zaidi S, Lu Q, Nelson-Williams C, Brooks ED, Bilguvar K, Tikhonova I, Mane S, Yang JF, Sawh-Martinez R, Persing S, Zellner EG, Loring E, Chuang C, Galm A, Hashim PW, Steinbacher DM, DiLuna ML, Duncan CC, Pelphrey KA, Zhao H, Persing JA, Lifton RP: Two locus inheritance of non-syndromic midline craniosynostosis via rare SMAD6 and common BMP2 alleles. Elife. 2016 Sep 8; 2016 Sep 8. PMID: 27606499

Bann D, Chen H, Bonell C, Glynn NW, Fielding RA, Manini T, King AC, Pahor M, Mihalko SL, Gill TM, Life Study investigators.: Socioeconomic differences in the benefits of structured physical activity compared with health education on the prevention of major mobility disability in older adults: the LIFE study. J Epidemiol Community Health. 2016 Sep; 2016 Apr 8. PMID: 27060177

Zhao B, Lu Q, Cheng Y, Belcher JM, Siew ED, Leaf DE, Body SC, Fox AA, Waikar SW, Collard CD, Thiessen-Philbrook H, Ikizler TA, Ware LB, Edelstein CL, Garg AX, Choi M, Schaub JA, Zhao H, Lifton RP, Parikh CR, TRIBE-AKI Consortium.: A Genome-Wide Association Study to Identify Single Nucleotide Polymorphisms for Acute Kidney Injury. Am J Respir Crit Care Med. 2016 Aug 30; 2016 Aug 30. PMID: 27576016

Liu Y, Zhao H: Predicting synergistic effects between compounds through their structural similarity and effects on transcriptomes. Bioinformatics. 2016 Aug 18; 2016 Aug 18. PMID: 27540269

Polimanti R, Yang BZ, Zhao H, Gelernter J: Evidence of Polygenic Adaptation in the Systems Genetics of Anthropometric Traits. PLoS One. 2016 Aug 18; 2016 Aug 18. PMID: 27537407

Mohile SG, Hurria A, Cohen HJ, Rowland JH, Leach CR, Arora NK, Canin B, Muss HB, Magnuson A, Flannery M, Lowenstein L, Allore HG, Mustian KM, Demark-Wahnefried W, Extermann M, Ferrell B, Inouye SK, Studenski SA, Dale W: Improving the quality of survivorship for older adults with cancer. Cancer. 2016 Aug 15; 2016 May 12. PMID: 27172129

Zhang X, Justice AC, Hu Y, Wang Z, Zhao H, Wang G, Johnson EO, Emu B, Sutton RE, Krystal JH, Xu K: Epigenome-wide differential DNA methylation between HIV-infected and uninfected individuals. Epigenetics. 2016 Aug 12; 2016 Aug 12. PMID: 27672717

Makris UE, Higashi RT, Marks EG, Fraenkel L, Gill TM, Friedly JL, Carrington Reid M: Physical, Emotional, and Social Impacts of Restricting Back Pain in Older Adults: A Qualitative Study. Pain Med. 2016 Aug 11; 2016 Aug 11. PMID: 27516362

Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM: Factors Associated with Functional Recovery among Older Intensive Care Unit Survivors. Am J Respir Crit Care Med. 2016 Aug 1. PMID: 26840348

Bandaranayake T, Shaw AC: Host Resistance and Immune Aging. Clin Geriatr Med. 2016 Aug; 2016 May 25. PMID: 27394014

Dharmarajan K, Strait KM, Tinetti ME, Lagu T, Lindenauer PK, Lynn J, Krukas MR, Ernst FR, Li SX, Krumholz HM: Treatment for Multiple Acute Cardiopulmonary Conditions in Older Adults Hospitalized with Pneumonia, Chronic Obstructive Pulmonary Disease, or Heart Failure. J Am Geriatr Soc. 2016 Aug; 2016 Jul 22. PMID: 27448329

Cunningham GR, Stephens-Shields AJ, Rosen RC, Wang C, Bhasin S, Matsumoto AM, Parsons JK, Gill TM, Molitch ME, Farrar JT, Cella D, Barrett-Connor E, Cauley JA, Cifelli D, Crandall JP, Ensrud KE, Gallagher L, Zeldow B, Lewis CE, Pahor M, Swerdloff RS, Hou X, Anton S, Basaria S, Diem SJ, Tabatabaie V, Ellenberg SS, Snyder PJ: Testosterone Treatment and Sexual Function in Older Men With Low Testosterone Levels. J Clin Endocrinol Metab. 2016 Aug; 2016 Jun 29. PMID: 27355400

Botoseneanu A, Allore HG, Mendes de Leon CF, Gahbauer EA, Gill TM: Sex Differences in Concomitant Trajectories of Self-Reported Disability and Measured Physical Capacity in Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Aug; 2016 Apr 12. PMID: 27071781

Allore HG, Zhan Y, Cohen AB, Tinetti ME, Trentalange M, McAvay G: Methodology to Estimate the Longitudinal Average Attributable Fraction of Guideline-recommended Medications for Death in Older Adults With Multiple Chronic Conditions. J Gerontol A Biol Sci Med Sci. 2016 Aug; 2016 Jan 8. PMID: 26748093

Cheraghlou S, Gahbauer EA, Leo-Summers L, Stabenau HF, Chaudhry SI, Gill TM: Restricting Symptoms Before and After Admission to Hospice. Am J Med. 2016 Jul; 2016 Mar 8. PMID: 26968471

Liu J, Yang C, Shi X, Li C, Huang J, Zhao H, Ma S: Analyzing Association Mapping in Pedigree-Based GWAS Using a Penalized Multitrait Mixed Model. Genet Epidemiol. 2016 Jul; 2016 Jun 1. PMID: 27247027

Tinetti M: Mainstream or Extinction: Can Defining Who We Are Save Geriatrics? J Am Geriatr Soc. 2016 Jul; 2016 Jun 28. PMID: 27351753

Magnuson A, Allore H, Cohen HJ, Mohile SG, Williams GR, Chapman A, Extermann M, Olin RL, Targia V, Mackenzie A, Holmes HM, Hurria A: Geriatric assessment with management in cancer care: Current evidence and potential mechanisms for future research. J Geriatr Oncol. 2016 Jul; 2016 Jul 5. PMID: 27197915

Williams GR, Mackenzie A, Magnuson A, Olin R, Chapman A, Mohile S, Allore H, Somerfield MR, Targia V, Extermann M, Cohen HJ, Hurria A, Holmes H: Comorbidity in older adults with cancer. J Geriatr Oncol. 2016 Jul; 2015 Dec 22. PMID: 26725537

Buford TW, Miller ME, Church TS, Gill TM, Henderson R, Hsu FC, McDermott MM, Nadkarni N, Pahor M, Stafford RS, Carter CS, LIFE Study Research Group.: Antihypertensive Use and the Effect of a Physical Activity Intervention in the Prevention of Major Mobility Disability Among Older Adults: The LIFE Study. J Gerontol A Biol Sci Med Sci. 2016 Jul; 2016 Feb 10. PMID: 26865496

Vaz Fragoso CA, McAvay G, Van Ness PH, Metter EJ, Ferrucci L, Yaggi HK, Concato J, Gill TM: Aging-Related Considerations When Evaluating the Forced Expiratory Volume in 1 Second (FEV1) Over Time. J Gerontol A Biol Sci Med Sci. 2016 Jul; 2015 Nov 2. PMID: 26525091

Wu X, Guarino P, Lo AC, Peduzzi P, Wininger M: Long-term Effectiveness of Intensive Therapy in Chronic Stroke. Neurorehabil Neural Repair. 2016 Jul; 2015 Oct 8. PMID: 26450442

Fried TR, Niehoff K, Tjia J, Redeker N, Goldstein MK: Erratum to: A Delphi process to address medication appropriateness for older persons with multiple chronic conditions. BMC Geriatr. 2016 Jun 16; 2016 Jun 16. PMID: 27312251

Li N, Subrahmanyan L, Smith E, Yu X, Zaidi S, Choi M, Mane S, Nelson-Williams C, Bahjati M, Kazemi M, Hashemi M, Fathzadeh M, Narayanan A, Tian L, Montazeri F, Mani M, Begleiter ML, Coon BG, Lynch HT, Olson EN, Zhao H, Ruland J, Lifton RP, Mani A: Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. Am J Hum Genet. 2016 Jun 2; 2016 May 12. PMID: 27181681

Chen M, Gao C, Zhao H: Posterior Contraction Rates of the Phylogenetic Indian Buffet Processes. Bayesian Anal. 2016 Jun; 2015 Jun 5. PMID: 27087886

Wang T, Chen M, Zhao H: Estimating DNA methylation levels by joint modeling of multiple methylation profiles from microarray data. Biometrics. 2016 Jun; 2015 Oct 4. PMID: 26433612

Ciarleglio MM, Arendt CD, Peduzzi PN: Selection of the effect size for sample size determination for a continuous response in a superiority clinical trial using a hybrid classical and Bayesian procedure. Clin Trials. 2016 Jun; 2016 Feb 29. PMID: 26928986

Han L, Gill TM, Jones BL, Allore HG: Cognitive Aging Trajectories and Burdens of Disability, Hospitalization and Nursing Home Admission Among Community-living Older Persons. J Gerontol A Biol Sci Med Sci. 2016 Jun; 2015 Oct 28. PMID: 26511011

Chima-Melton C, Murphy TE, Araujo KL, Pisani MA: The Impact of Race on Intensity of Care Provided to Older Adults in the Medical Intensive Care Unit. J Racial Ethn Health Disparities. 2016 Jun; 2015 Sep 28. PMID: 27271078

Niehoff KM, Rajeevan N, Charpentier PA, Miller PL, Goldstein MK, Fried TR: Development of the Tool to Reduce Inappropriate Medications (TRIM): A Clinical Decision Support System to Improve Medication Prescribing for Older Adults. Pharmacotherapy. 2016 Jun; 2016 May 28. PMID: 27041466

Bramley K, Pisani MA, Murphy TE, Araujo KL, Homer RJ, Puchalski JT: Endobronchial Ultrasound-Guided Cautery-Assisted Transbronchial Forceps Biopsies: Safety and Sensitivity Relative to Transbronchial Needle Aspiration. Ann Thorac Surg. 2016 May; 2016 Feb 22. PMID: 26912301

Tinetti ME, Esterson J, Ferris R, Posner P, Blaum CS: Patient Priority-Directed Decision Making and Care for Older Adults with Multiple Chronic Conditions. Clin Geriatr Med. 2016 May; 2016 Feb 28. PMID: 27113145

Marsh AP, Applegate WB, Guralnik JM, Jack Rejeski W, Church TS, Fielding RA, Gill TM, King AC, Kritchevsky SB, Manini TM, McDermott MM, Newman AB, Stowe CL, Walkup MP, Pahor M, Miller ME, LIFE Study Investigators.: Hospitalizations During a Physical Activity Intervention in Older Adults at Risk of Mobility Disability: Analyses from the Lifestyle Interventions and Independence for Elders Randomized Clinical Trial. J Am Geriatr Soc. 2016 May. PMID: 27225353

Groessl EJ, Kaplan RM, Castro Sweet CM, Church T, Espeland MA, Gill TM, Glynn NW, King AC, Kritchevsky S, Manini T, McDermott MM, Reid KF, Rushing J, Pahor M, LIFE Study Group.: Cost-effectiveness of the LIFE Physical Activity Intervention for Older Adults at Increased Risk for Mobility Disability. J Gerontol A Biol Sci Med Sci. 2016 May; 2016 Feb 17. PMID: 26888433

Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J: Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. JAMA Psychiatry. 2016 May 1. PMID: 27028160

Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, Staeheli P, Iwasaki A: Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science. 2016 Apr 22. PMID: 27102485

Xie Z, Zhang D, Chung D, Tang Z, Huang H, Dai L, Qi S, Li J, Colak G, Chen Y, Xia C, Peng C, Ruan H, Kirkey M, Wang D, Jensen LM, Kwon OK, Lee S, Pletcher SD, Tan M, Lombard DB, White KP, Zhao H, Li J, Roeder RG, Yang X, Zhao Y: Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation. Mol Cell. 2016 Apr 21. PMID: 27105115

Lu Q, Powles RL, Wang Q, He BJ, Zhao H: Integrative Tissue-Specific Functional Annotations in the Human Genome Provide Novel Insights on Many Complex Traits and Improve Signal Prioritization in Genome Wide Association Studies. PLoS Genet. 2016 Apr 8; 2016 Apr 8. PMID: 27058395

Kernan WN, Viscoli CM, Furie KL, Young LH, Inzucchi SE, Gorman M, Guarino PD, Lovejoy AM, Peduzzi PN, Conwit R, Brass LM, Schwartz GG, Adams HP Jr, Berger L, Carolei A, Clark W, Coull B, Ford GA, Kleindorfer D, O'Leary JR, Parsons MW, Ringleb P, Sen S, Spence JD, Tanne D, Wang D, Winder TR, IRIS Trial Investigators.: Pioglitazone after Ischemic Stroke or Transient Ischemic Attack. N Engl J Med. 2016 Apr 7; 2016 Feb 17. PMID: 26886418

Vaz Fragoso CA, McAvay G, Van Ness PH, Casaburi R, Jensen RL, MacIntyre N, Yaggi HK, Gill TM, Concato J: Phenotype of Spirometric Impairment in an Aging Population. Am J Respir Crit Care Med. 2016 Apr 1. PMID: 26540012

Feder SL, Schulman-Green D, Dodson JA, Geda M, Williams K, Nanna MG, Allore HG, Murphy TE, Tinetti ME, Gill TM, Chaudhry SI: Risk Stratification in Older Patients With Acute Myocardial Infarction: Physicians' Perspectives. J Aging Health. 2016 Apr; 2015 Jun 22. PMID: 26100619

Monin J, Doyle M, Levy B, Schulz R, Fried T, Kershaw T: Spousal Associations Between Frailty and Depressive Symptoms: Longitudinal Findings from the Cardiovascular Health Study. J Am Geriatr Soc. 2016 Apr. PMID: 27100578

Dodson JA, Petrone A, Gagnon DR, Tinetti ME, Krumholz HM, Gaziano JM: Incidence and Determinants of Traumatic Intracranial Bleeding Among Older Veterans Receiving Warfarin for Atrial Fibrillation. JAMA Cardiol. 2016 Apr 1. PMID: 27437657

Tinetti ME, Naik AD, Dodson JA: Moving From Disease-Centered to Patient Goals-Directed Care for Patients With Multiple Chronic Conditions: Patient Value-Based Care. JAMA Cardiol. 2016 Apr 1. PMID: 27437646

Erekson EA, Li FY, Martin DK, Fried TR: Vulvovaginal symptoms prevalence in postmenopausal women and relationship to other menopausal symptoms and pelvic floor disorders. Menopause. 2016 Apr. PMID: 26645820

Ryslik GA, Cheng Y, Modis Y, Zhao H: Leveraging protein quaternary structure to identify oncogenic driver mutations. BMC Bioinformatics. 2016 Mar 22; 2016 Mar 22. PMID: 27001666

Fried TR, Niehoff K, Tjia J, Redeker N, Goldstein MK: A Delphi process to address medication appropriateness for older persons with multiple chronic conditions. BMC Geriatr. 2016 Mar 15; 2016 Mar 15. PMID: 26979576

Hu Y, Zhao H: CCor: A whole genome network-based similarity measure between two genes. Biometrics. 2016 Mar 8; 2016 Mar 8. PMID: 26953524

Yan X, Chu JH, Gomez J, Koenigs M, Holm C, He X, Perez MF, Zhao H, Mane S, Martinez FD, Ober C, Nicolae DL, Barnes KC, London SJ, Gilliland F, Weiss ST, Raby BA, Cohn L, Chupp GL: Noninvasive Analysis of the Sputum Transcriptome Discriminates Clinical Phenotypes of Asthma. Ann Am Thorac Soc. 2016 Mar. PMID: 27027945

Chen M, Lin H, Zhao H: CHANGE POINT ANALYSIS OF HISTONE MODIFICATIONS REVEALS EPIGENETIC BLOCKS LINKING TO PHYSICAL DOMAINS. Ann Appl Stat. 2016 Mar; 2016 Mar 25. PMID: 27231496

Vaz Fragoso CA, Beavers DP, Anton SD, Liu CK, McDermott MM, Newman AB, Pahor M, Stafford RS, Gill TM, Lifestyle Interventions and Independence in Elders Investigators.: Effect of Structured Physical Activity on Respiratory Outcomes in Sedentary Elderly Adults with Mobility Limitations. J Am Geriatr Soc. 2016 Mar. PMID: 27000324

Dodson JA, Arnold SV, Gosch KL, Gill TM, Spertus JA, Krumholz HM, Rich MW, Chaudhry SI, Forman DE, Masoudi FA, Alexander KP: Slow Gait Speed and Risk of Mortality or Hospital Readmission After Myocardial Infarction in the Translational Research Investigating Underlying Disparities in Recovery from Acute Myocardial Infarction: Patients' Health Status Registry. J Am Geriatr Soc. 2016 Mar; 2016 Mar 1. PMID: 26926309

Buurman BM, Han L, Murphy TE, Gahbauer EA, Leo-Summers L, Allore HG, Gill TM: Trajectories of Disability Among Older Persons Before and After a Hospitalization Leading to a Skilled Nursing Facility Admission. J Am Med Dir Assoc. 2016 Mar 1; 2015 Nov 24. PMID: 26620073

Chen M, Ren Z, Zhao H, Zhou H: Asymptotically Normal and Efficient Estimation of Covariate-Adjusted Gaussian Graphical Model. J Am Stat Assoc. 2016 Mar; 2016 May 5. PMID: 27499564

Ng R, Allore HG, Monin JK, Levy BR: Retirement as Meaningful: Positive Retirement Stereotypes Associated with Longevity. J Soc Issues. 2016 Mar; 2016 Mar 9. PMID: 27346893

Buurman BM, Parlevliet JL, Allore HG, Blok W, van Deelen BA, Moll van Charante EP, de Haan RJ, de Rooij SE: Comprehensive Geriatric Assessment and Transitional Care in Acutely Hospitalized Patients: The Transitional Care Bridge Randomized Clinical Trial. JAMA Intern Med. 2016 Mar. PMID: 26882111

Snyder PJ, Bhasin S, Cunningham GR, Matsumoto AM, Stephens-Shields AJ, Cauley JA, Gill TM, Barrett-Connor E, Swerdloff RS, Wang C, Ensrud KE, Lewis CE, Farrar JT, Cella D, Rosen RC, Pahor M, Crandall JP, Molitch ME, Cifelli D, Dougar D, Fluharty L, Resnick SM, Storer TW, Anton S, Basaria S, Diem SJ, Hou X, Mohler ER 3rd, Parsons JK, Wenger NK, Zeldow B, Landis JR, Ellenberg SS, Testosterone Trials Investigators.: Effects of Testosterone Treatment in Older Men. N Engl J Med. 2016 Feb 18. PMID: 26886521

Lu Q, Yao X, Hu Y, Zhao H: GenoWAP: GWAS signal prioritization through integrated analysis of genomic functional annotation. Bioinformatics. 2016 Feb 15; 2015 Oct 25. PMID: 26504140

Gill TM, Pahor M, Guralnik JM, McDermott MM, King AC, Buford TW, Strotmeyer ES, Nelson ME, Sink KM, Demons JL, Kashaf SS, Walkup MP, Miller ME, LIFE Study Investigators.: Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study). BMJ. 2016 Feb 3; 2016 Feb 3. PMID: 26842425

Huang X, Stern DF, Zhao H: Transcriptional Profiles from Paired Normal Samples Offer Complementary Information on Cancer Patient Survival--Evidence from TCGA Pan-Cancer Data. Sci Rep. 2016 Feb 3; 2016 Feb 3. PMID: 26837275

Fragoso CA, Heffelfinger C, Zhao H, Dellaporta SL: Imputing Genotypes in Biallelic Populations from Low-Coverage Sequence Data. Genetics. 2016 Feb; 2015 Dec 29. PMID: 26715670

Fried TR, Redding CA, Robbins ML, Paiva AL, O'Leary JR, Iannone L: Development of Personalized Health Messages to Promote Engagement in Advance Care Planning. J Am Geriatr Soc. 2016 Feb; 2016 Jan 25. PMID: 26804791

Rowe T, Araujo KL, Van Ness PH, Pisani MA, Juthani-Mehta M: Outcomes of Older Adults With Sepsis at Admission to an Intensive Care Unit. Open Forum Infect Dis. 2016 Jan 21; 2016 Jan 21. PMID: 26925430

Fried TR: Shared Decision Making--Finding the Sweet Spot. N Engl J Med. 2016 Jan 14. PMID: 26760081

Wang F, Xu H, Zhao H, Gelernter J, Zhang H: DNA co-methylation modules in postmortem prefrontal cortex tissues of European Australians with alcohol use disorders. Sci Rep. 2016 Jan 14; 2016 Jan 14. PMID: 26763658

Esserman D, Allore HG, Travison TG: The Method of Randomization for Cluster-Randomized Trials: Challenges of Including Patients with Multiple Chronic Conditions. Int J Stat Med Res. 2016 Jan 8. PMID: 27478520

Perkins SM, Bacchetti P, Davey CS, Lindsell CJ, Mazumdar M, Oster RA, Peduzzi PN, Rocke DM, Rudser KD, Kim M: Best Practices for Biostatistical Consultation and Collaboration in Academic Health Centers. Am Stat. 2016; 2016 Jun 9. PMID: 27777443

Connolly MA, Trentalange M, Zeiss CJ: Long-Term Clinical Outcomes in Diabetic Rhesus Macaques (Macaca mulatta) Treated with Medroxyprogesterone Acetate for Endometriosis. Comp Med. 2016. PMID: 27538865

Goffredo M, Caprio S, Feldstein AE, D'Adamo E, Shaw MM, Pierpont B, Savoye M, Zhao H, Bale AE, Santoro N: Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study. Hepatology. 2016 Jan; 2015 Nov 16. PMID: 26457389

Allore H: Special Issue: Methods for Estimating Treatment Effects for Persons with Multiple Chronic Conditions. Int J Stat Med Res. 2016. PMID: 27559427

Han L, Pisani MA, Araujo KL, Allore HG: Use of Self-Matching to Control for Stable Patient Characteristics While Addressing Time-Varying Confounding on Treatment Effect: A Case Study of Older Intensive Care Patients. Int J Stat Med Res. 2016; 2016 Jan 8. PMID: 27123153

Allore H, McAvay G, Vaz Fragoso CA, Murphy TE: Individualized Absolute Risk Calculations for Persons with Multiple Chronic Conditions: Embracing Heterogeneity, Causality, and Competing Events. Int J Stat Med Res. 2016. PMID: 27076862

Johnson MJ, Bland JM, Gahbauer EA, Ekström M, Sinnarajah A, Gill TM, Currow DC: Breathlessness in Elderly Adults During the Last Year of Life Sufficient to Restrict Activity: Prevalence, Pattern, and Associated Factors. J Am Geriatr Soc. 2016 Jan. PMID: 26782854

Ramaswamy A, Homer R, Killam J, Pisani MA, Murphy TE, Araujo K, Puchalski J: Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease. J Bronchology Interv Pulmonol. 2016 Jan. PMID: 26705007

Malawista A, Wang X, Trentalange M, Allore HG, Montgomery RR: Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogeny. Macrophage (Houst). 2016; 2016 Apr 22. PMID: 27695708

Harvey PD, Aslan M, Du M, Zhao H, Siever LJ, Pulver A, Gaziano JM, Concato J: Factor structure of cognition and functional capacity in two studies of schizophrenia and bipolar disorder: Implications for genomic studies. Neuropsychology. 2016 Jan. PMID: 26710094

Lu Q, Jin C, Sun J, Bowler R, Kechris K, Kaminski N, Zhao H: Post-GWAS Prioritization Through Data Integration Provides Novel Insights on Chronic Obstructive Pulmonary Disease. Stat Biosci. 2016; 2016 Jun 13. PMID: 27812370

King AC, Salvo D, Banda JA, Ahn DK, Gill TM, Miller M, Newman AB, Fielding RA, Siordia C, Moore S, Folta S, Spring B, Manini T, Pahor M, LIFE Study Investigators.: An observational study identifying obese subgroups among older adults at increased risk of mobility disability: do perceptions of the neighborhood environment matter? Int J Behav Nutr Phys Act. 2015 Dec 18; 2015 Dec 18. PMID: 26684894

Li G, Zhao H: M(3)-S: a genotype calling method incorporating information from samples with known genotypes. BMC Bioinformatics. 2015 Dec 3; 2015 Dec 3. PMID: 26634345

Murphy TE, Araujo KL, Pisani MA: The authors reply. Crit Care Med. 2015 Dec. PMID: 26575672

Montgomery RR, Shaw AC: Paradoxical changes in innate immunity in aging: recent progress and new directions. J Leukoc Biol. 2015 Dec; 2015 Jul 17. PMID: 26188078

Fraenkel L, Matzko CK, Webb DE, Oppermann B, Charpentier P, Peters E, Reyna V, Newman ED: Use of Decision Support for Improved Knowledge, Values Clarification, and Informed Choice in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2015 Nov. PMID: 26195173

Wang Q, Yang C, Gelernter J, Zhao H: Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS. Hum Genet. 2015 Nov; 2015 Sep 4. PMID: 26340901

Levy BR, Slade MD, Chung PH, Gill TM: Resiliency Over Time of Elders' Age Stereotypes After Encountering Stressful Events. J Gerontol B Psychol Sci Soc Sci. 2015 Nov; 2014 Jul 5. PMID: 24997287

Polimanti R, Zhang H, Smith AH, Zhao H, Farrer LA, Kranzler HR, Gelernter J: Genome-wide association study of body mass index in subjects with alcohol dependence. Addict Biol. 2015 Oct 12; 2015 Oct 12. PMID: 26458734

Tinetti ME, McAvay G, Trentalange M, Cohen AB, Allore HG: Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study. BMJ. 2015 Oct 2; 2015 Oct 2. PMID: 26432468

Vaz Fragoso CA, McAvay G, Van Ness PH, Casaburi R, Jensen RL, MacIntyre N, Gill TM, Yaggi HK, Concato J: Phenotype of normal spirometry in an aging population. Am J Respir Crit Care Med. 2015 Oct 1. PMID: 26114439

Monin JK, Levy B, Chen B, Fried T, Stahl ST, Schulz R, Doyle M, Kershaw T: Husbands' and Wives' Physical Activity and Depressive Symptoms: Longitudinal Findings from the Cardiovascular Health Study. Ann Behav Med. 2015 Oct. PMID: 25868508

Fang H, Huang C, Zhao H, Deng M: CCLasso: correlation inference for compositional data through Lasso. Bioinformatics. 2015 Oct 1; 2015 Jun 4. PMID: 26048598

Shih AF, Buurman BM, Tynan-McKiernan K, Tinetti ME, Jenq G: Views of Primary Care Physicians and Home Care Nurses on the Causes of Readmission of Older Adults. J Am Geriatr Soc. 2015 Oct. PMID: 26480986

Cohen AB, Wright MS, Cooney L Jr, Fried T: Guardianship and End-of-Life Decision Making. JAMA Intern Med. 2015 Oct. PMID: 26258634

Pang H, Kim I, Zhao H: Random Effects Model for Multiple Pathway Analysis with Applications to Type II Diabetes Microarray Data. Stat Biosci. 2015 Oct 1; 2014 Jan 30. PMID: 26640601

Bell SP, Orr NM, Dodson JA, Rich MW, Wenger NK, Blum K, Harold JG, Tinetti ME, Maurer MS, Forman DE: What to Expect From the Evolving Field of Geriatric Cardiology. J Am Coll Cardiol. 2015 Sep 15. PMID: 26361161

Shin MS, You S, Kang Y, Lee N, Yoo SA, Park K, Kang KS, Kim SH, Mohanty S, Shaw AC, Montgomery RR, Hwang D, Kang I: DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine. J Immunol. 2015 Sep 15; 2015 Aug 14. PMID: 26276874

Allore HG, Zhan Y, Tinetti M, Trentalange M, McAvay G: Longitudinal average attributable fraction as a method for studying time-varying conditions and treatments on recurrent self-rated health: the case of medications in older adults with multiple chronic conditions. Ann Epidemiol. 2015 Sep; 2015 May 8. PMID: 26033374

Vaz Fragoso CA, Van Ness PH, Araujo KL, Iannone LP, Klar Yaggi H: Age-Related Differences in Sleep-Wake Symptoms of Adults Undergoing Polysomnography. J Am Geriatr Soc. 2015 Sep. PMID: 26389988

Swerdloff RS, Pak Y, Wang C, Liu PY, Bhasin S, Gill TM, Matsumoto AM, Pahor M, Surampudi P, Snyder PJ: Serum Testosterone (T) Level Variability in T Gel-Treated Older Hypogonadal Men: Treatment Monitoring Implications. J Clin Endocrinol Metab. 2015 Sep; 2015 Jun 29. PMID: 26120790

Cauley JA, Fluharty L, Ellenberg SS, Gill TM, Ensrud KE, Barrett-Connor E, Cifelli D, Cunningham GR, Matsumoto AM, Bhasin S, Pahor M, Farrar JT, Cella D, Rosen RC, Resnick SM, Swerdloff RS, Lewis CE, Molitch ME, Crandall JP, Stephens-Shields AJ, Strorer TW, Wang C, Anton S, Basaria S, Diem S, Tabatabaie V, Dougar D, Hou X, Snyder PJ: Recruitment and Screening for the Testosterone Trials. J Gerontol A Biol Sci Med Sci. 2015 Sep; 2015 Apr 15. PMID: 25878029

DeBiasi EM, Pisani MA, Murphy TE, Araujo K, Kookoolis A, Argento AC, Puchalski J: Mortality among patients with pleural effusion undergoing thoracentesis. Eur Respir J. 2015 Aug; 2015 Apr 2. PMID: 25837039

Vaz Fragoso CA, Araujo K, Leo-Summers L, Van Ness PH: Lower Extremity Proximal Muscle Function and Dyspnea in Older Persons. J Am Geriatr Soc. 2015 Aug; 2015 Jul 22. PMID: 26200804

Case SM, O'Leary J, Kim N, Tinetti ME, Fried TR: Older Adults' Recognition of Trade-Offs in Healthcare Decision-Making. J Am Geriatr Soc. 2015 Aug; 2015 Jul 14. PMID: 26173743

Espeland MA, Newman AB, Sink K, Gill TM, King AC, Miller ME, Guralnik J, Katula J, Church T, Manini T, Reid KF, McDermott MM, LIFE Study Group.: Associations Between Ankle-Brachial Index and Cognitive Function: Results From the Lifestyle Interventions and Independence for Elders Trial. J Am Med Dir Assoc. 2015 Aug 1; 2015 Apr 11. PMID: 25869993

Cohen AB, Trentalange M, Fried T: Surrogate Decision Making for Patients Without Nuclear Family. JAMA. 2015 Jul 28. PMID: 26219065

Xu K, Kranzler HR, Sherva R, Sartor CE, Almasy L, Koesterer R, Zhao H, Farrer LA, Gelernter J: Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. Alcohol Clin Exp Res. 2015 Jul; 2015 Jun 3. PMID: 26036284

Vaz Fragoso CA, Miller ME, King AC, Kritchevsky SB, Liu CK, Myers VH, Nadkarni NK, Pahor M, Spring BJ, Gill TM, Lifestyle Interventions and Independence for Elders Study Group.: Effect of Structured Physical Activity on Sleep-Wake Behaviors in Sedentary Elderly Adults with Mobility Limitations. J Am Geriatr Soc. 2015 Jul; 2015 Jun 26. PMID: 26115386

Gill TM, Allore HG, Gahbauer EA, Han L: Establishing a Hierarchy for the Two Components of Restricted Activity. J Gerontol A Biol Sci Med Sci. 2015 Jul; 2014 Nov 12. PMID: 25391532

Xu X, Liang J, Bennett JM, Botoseneanu A, Allore HG: Socioeconomic stratification and multidimensional health trajectories: evidence of convergence in later old age. J Gerontol B Psychol Sci Soc Sci. 2015 Jul; 2014 Aug 26. PMID: 25161216

Yang C, Li C, Wang Q, Chung D, Zhao H: Implications of pleiotropy: challenges and opportunities for mining Big Data in biomedicine. Front Genet. 2015 Jun 30; 2015 Jun 30. PMID: 26175753

Brummel NE, Balas MC, Morandi A, Ferrante LE, Gill TM, Ely EW: Understanding and reducing disability in older adults following critical illness. Crit Care Med. 2015 Jun. PMID: 25756418

Lu Q, Hu Y, Sun J, Cheng Y, Cheung KH, Zhao H: A statistical framework to predict functional non-coding regions in the human genome through integrated analysis of annotation data. Sci Rep. 2015 May 27; 2015 May 27. PMID: 26015273

Gill TM, Gahbauer EA, Han L, Allore HG: The role of intervening hospital admissions on trajectories of disability in the last year of life: prospective cohort study of older people. BMJ. 2015 May 20; 2015 May 20. PMID: 25995357

Xie Y, Jin Y, Merenick BL, Ding M, Fetalvero KM, Wagner RJ, Mai A, Gleim S, Tucker DF, Birnbaum MJ, Ballif BA, Luciano AK, Sessa WC, Rzucidlo EM, Powell RJ, Hou L, Zhao H, Hwa J, Yu J, Martin KA: Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition. Sci Signal. 2015 May 12; 2015 May 12. PMID: 25969542

Ahasic AM, Van Ness PH, Murphy TE, Araujo KL, Pisani MA: Functional status after critical illness: agreement between patient and proxy assessments. Age Ageing. 2015 May; 2014 Oct 16. PMID: 25324334

Pisani MA, Araujo KL, Murphy TE: Association of cumulative dose of haloperidol with next-day delirium in older medical ICU patients. Crit Care Med. 2015 May. PMID: 25746748

Rejeski WJ, Rushing J, Guralnik JM, Ip EH, King AC, Manini TM, Marsh AP, McDermott MM, Fielding RA, Newman AB, Tudor-Locke C, Gill TM, LIFE Study Group.: The MAT-sf: identifying risk for major mobility disability. J Gerontol A Biol Sci Med Sci. 2015 May; 2015 Feb 13. PMID: 25680917

Walker WE, Kurscheid S, Joshi S, Lopez CA, Goh G, Choi M, Barakat L, Francis J, Fisher A, Kozal M, Zapata H, Shaw A, Lifton R, Sutton RE, Fikrig E: Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers. J Virol. 2015 May; 2015 Mar 4. PMID: 25740989

Zheng C, Dalla Man C, Cobelli C, Groop L, Zhao H, Bale AE, Shaw M, Duran E, Pierpont B, Caprio S, Santoro N: A common variant in the MTNR1b gene is associated with increased risk of impaired fasting glucose (IFG) in youth with obesity. Obesity (Silver Spring). 2015 May. PMID: 25919927

Stefani G, Chen X, Zhao H, Slack FJ: A novel mechanism of LIN-28 regulation of let-7 microRNA expression revealed by in vivo HITS-CLIP in C. elegans. RNA. 2015 May; 2015 Mar 24. PMID: 25805859

Zuo L, Zhang CK, Sayward FG, Cheung KH, Wang K, Krystal JH, Zhao H, Luo X: Gene-based and pathway-based genome-wide association study of alcohol dependence. Shanghai Arch Psychiatry. 2015 Apr 25. PMID: 26120261

Wang Q, Lu Q, Zhao H: A review of study designs and statistical methods for genomic epidemiology studies using next generation sequencing. Front Genet. 2015 Apr 20; 2015 Apr 20. PMID: 25941534

Makris UE, Higashi RT, Marks EG, Fraenkel L, Sale JE, Gill TM, Reid MC: Ageism, negative attitudes, and competing co-morbidities--why older adults may not seek care for restricting back pain: a qualitative study. BMC Geriatr. 2015 Apr 8; 2015 Apr 8. PMID: 25887905

Cohen AB, Trentalange M, Fried T: Patients with next-of-kin relationships outside the nuclear family. JAMA. 2015 Apr 7. PMID: 25849183

Tadeu AM, Lin S, Hou L, Chung L, Zhong M, Zhao H, Horsley V: Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells. PLoS One. 2015 Apr 7; 2015 Apr 7. PMID: 25849374

Hartaigh Bó, Allore HG, Trentalange M, McAvay G, Pilz S, Dodson JA, Gill TM: Elevations in time-varying resting heart rate predict subsequent all-cause mortality in older adults. Eur J Prev Cardiol. 2015 Apr; 2014 Jan 20. PMID: 24445263

Zapata HJ, Quagliarello VJ: The microbiota and microbiome in aging: potential implications in health and age-related diseases. J Am Geriatr Soc. 2015 Apr; 2015 Apr 8. PMID: 25851728

Howell BA, Azar MM, Landry ML, Shaw AC: Toscana virus encephalitis in a traveler returning to the United States. J Clin Microbiol. 2015 Apr; 2015 Feb 11. PMID: 25673791

Qi X, Luo R, Carroll RJ, Zhao H: Sparse Regression by Projection and Sparse Discriminant Analysis. J Comput Graph Stat. 2015 Apr 1. PMID: 26345204

Mohanty S, Joshi SR, Ueda I, Wilson J, Blevins TP, Siconolfi B, Meng H, Devine L, Raddassi K, Tsang S, Belshe RB, Hafler DA, Kaech SM, Kleinstein SH, Trentalange M, Allore HG, Shaw AC: Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. J Infect Dis. 2015 Apr 1; 2014 Nov 2. PMID: 25367297

Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM: Functional trajectories among older persons before and after critical illness. JAMA Intern Med. 2015 Apr. PMID: 25665067

Bean-Mayberry B, Bastian L, Trentalange M, Murphy TE, Skanderson M, Allore H, Reyes-Harvey E, Maisel NC, Gaetano V, Wright S, Haskell S, Brandt C: Associations between provider designation and female-specific cancer screening in women Veterans. Med Care. 2015 Apr. PMID: 25767975

Lam W, Jiang Z, Guan F, Huang X, Hu R, Wang J, Bussom S, Liu SH, Zhao H, Yen Y, Cheng YC: PHY906(KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment. Sci Rep. 2015 Mar 30; 2015 Mar 30. PMID: 25819872

Juthani-Mehta M, Van Ness PH, McGloin J, Argraves S, Chen S, Charpentier P, Miller L, Williams K, Wall D, Baker D, Tinetti M, Peduzzi P, Quagliarello VJ: A cluster-randomized controlled trial of a multicomponent intervention protocol for pneumonia prevention among nursing home elders. Clin Infect Dis. 2015 Mar 15; 2014 Dec 16. PMID: 25520333

Erekson EA, Ciarleglio MM, Hanissian PD, Strohbehn K, Bynum JP, Fried TR: Functional disability among older women with fecal incontinence. Am J Obstet Gynecol. 2015 Mar; 2014 Oct 15. PMID: 25447956

Lin Z, Sanders SJ, Li M, Sestan N, State MW, Zhao H: A MARKOV RANDOM FIELD-BASED APPROACH TO CHARACTERIZING HUMAN BRAIN DEVELOPMENT USING SPATIAL-TEMPORAL TRANSCRIPTOME DATA. Ann Appl Stat. 2015 Mar. PMID: 26877824

Gelernter J, Kranzler HR, Sherva R, Almasy L, Herman AI, Koesterer R, Zhao H, Farrer LA: Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Biol Psychiatry. 2015 Mar 1; 2014 Sep 16. PMID: 25555482

Ciarleglio MM, Arendt CD, Makuch RW, Peduzzi PN: Selection of the treatment effect for sample size determination in a superiority clinical trial using a hybrid classical and Bayesian procedure. Contemp Clin Trials. 2015 Mar; 2015 Jan 9. PMID: 25583273

Madden GR, Argraves SM, Van Ness PH, Juthani-Mehta M: Antibiotic susceptibility of urinary isolates in nursing home residents consuming cranberry capsules versus placebo. Infect Control Hosp Epidemiol. 2015 Mar. PMID: 25695180

Gill TM, Allore HG, Gahbauer EA, Murphy TE: The role of intervening illnesses and injuries in prolonging the disabling process. J Am Geriatr Soc. 2015 Mar; 2015 Mar 4. PMID: 25735396

Gross CP, Fried TR, Tinetti ME, Ross JS, Genao I, Hossain S, Wolf E, Lewis CL: Decision-making and cancer screening: a qualitative study of older adults with multiple chronic conditions. J Geriatr Oncol. 2015 Mar; 2014 Dec 17. PMID: 25544380

Li D, Zhao H, Kranzler HR, Li MD, Jensen KP, Zayats T, Farrer LA, Gelernter J: Genome-wide association study of copy number variations (CNVs) with opioid dependence. Neuropsychopharmacology. 2015 Mar; 2014 Sep 27. PMID: 25345593

Evans BR, Gloria-Soria A, Hou L, McBride C, Bonizzoni M, Zhao H, Powell JR: A Multipurpose, High-Throughput Single-Nucleotide Polymorphism Chip for the Dengue and Yellow Fever Mosquito, Aedes aegypti. G3 (Bethesda). 2015 Feb 26; 2015 Feb 26. PMID: 25721127

Sun J, Zhao H: The application of sparse estimation of covariance matrix to quadratic discriminant analysis. BMC Bioinformatics. 2015 Feb 18; 2015 Feb 18. PMID: 25886892

Ng R, Allore HG, Trentalange M, Monin JK, Levy BR: Increasing negativity of age stereotypes across 200 years: evidence from a database of 400 million words. PLoS One. 2015 Feb 12; 2015 Feb 12. PMID: 25675438

Bann D, Hire D, Manini T, Cooper R, Botoseneanu A, McDermott MM, Pahor M, Glynn NW, Fielding R, King AC, Church T, Ambrosius WT, Gill TM, LIFE Study Group.: Light Intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study. PLoS One. 2015 Feb 3; 2015 Feb 3. PMID: 25647685

Botoseneanu A, Ambrosius WT, Beavers DP, de Rekeneire N, Anton S, Church T, Folta SC, Goodpaster BH, King AC, Nicklas BJ, Spring B, Wang X, Gill TM, LIFE Study Groups.: Prevalence of metabolic syndrome and its association with physical capacity, disability, and self-rated health in Lifestyle Interventions and Independence for Elders Study participants. J Am Geriatr Soc. 2015 Feb; 2015 Jan 30. PMID: 25645664

Marcus BS, McAvay G, Gill TM, Vaz Fragoso CA: Respiratory symptoms, spirometric respiratory impairment, and respiratory disease in middle-aged and older persons. J Am Geriatr Soc. 2015 Feb; 2015 Jan 30. PMID: 25643966

Cesari M, Vellas B, Hsu FC, Newman AB, Doss H, King AC, Manini TM, Church T, Gill TM, Miller ME, Pahor M, LIFE Study Group.: A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study. J Gerontol A Biol Sci Med Sci. 2015 Feb; 2014 Nov 11. PMID: 25387728

Jenq GY, Tinetti ME: Post-acute care: who belongs where? JAMA Intern Med. 2015 Feb. PMID: 25437105

Foxman EF, Storer JA, Fitzgerald ME, Wasik BR, Hou L, Zhao H, Turner PE, Pyle AM, Iwasaki A: Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells. Proc Natl Acad Sci U S A. 2015 Jan 20; 2015 Jan 5. PMID: 25561542

Thakar J, Mohanty S, West AP, Joshi SR, Ueda I, Wilson J, Meng H, Blevins TP, Tsang S, Trentalange M, Siconolfi B, Park K, Gill TM, Belshe RB, Kaech SM, Shadel GS, Kleinstein SH, Shaw AC: Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination. Aging (Albany NY). 2015 Jan. PMID: 25596819

Stabenau HF, Morrison LJ, Gahbauer EA, Leo-Summers L, Allore HG, Gill TM: Functional trajectories in the year before hospice. Ann Fam Med. 2015 Jan-Feb. PMID: 25583890

Rabinowitz PM, Slizovskiy IB, Lamers V, Trufan SJ, Holford TR, Dziura JD, Peduzzi PN, Kane MJ, Reif JS, Weiss TR, Stowe MH: Proximity to natural gas wells and reported health status: results of a household survey in Washington County, Pennsylvania. Environ Health Perspect. 2015 Jan; 2014 Sep 10. PMID: 25204871

Murphy TE, Allore HG, Han L, Peduzzi PN, Gill TM, Xu X, Lin H: A longitudinal, observational study with many repeated measures demonstrated improved precision of individual survival curves using Bayesian joint modeling of disability and survival. Exp Aging Res. 2015. PMID: 25978444

Erekson EA, Ciarleglio MM, Hanissian PD, Strohbehn K, Bynum JP, Fried TR: Functional disability and compromised mobility among older women with urinary incontinence. Female Pelvic Med Reconstr Surg. 2015 May-Jun. PMID: 25185600

Feder SL, Schulman-Green D, Geda M, Williams K, Dodson JA, Nanna MG, Allore HG, Murphy TE, Tinetti ME, Gill TM, Chaudhry SI: Physicians' perceptions of the Thrombolysis in Myocardial Infarction (TIMI) risk score in older adults with acute myocardial infarction. Heart Lung. 2015 Sep-Oct; 2015 Jul 9. PMID: 26164651

Hopper K, Fried TR, Pisani MA: Health care worker attitudes and identified barriers to patient sleep in the medical intensive care unit. Heart Lung. 2015 Mar-Apr; 2015 Feb 14. PMID: 25686516

Joshi SR, Mohanty S, Shaw AC: Multicolor Digital Flow Cytometry in Human Translational Immunology. Methods Mol Biol. 2015. PMID: 26420708

Polimanti R, Yang C, Zhao H, Gelernter J: Dissecting ancestry genomic background in substance dependence genome-wide association studies. Pharmacogenomics. 2015; 2015 Aug 12. PMID: 26267224

Argento AC, Murphy TE, Pisani MA, Araujo KL, Puchalski J: Patient-Centered Outcomes Following Thoracentesis. Pleura (Thousand Oaks). 2015 Jan-Dec; 2015 Sep 1. PMID: 26767192

Yao Y, Liu R, Shin MS, Trentalange M, Allore H, Nassar A, Kang I, Pober JS, Montgomery RR: CyTOF supports efficient detection of immune cell subsets from small samples. J Immunol Methods. 2014 Dec 15; 2014 Nov 4. PMID: 25450003

Pang H, Zhao H: Stratified pathway analysis to identify gene sets associated with oral contraceptive use and breast cancer. Cancer Inform. 2014 Dec 9; 2014 Dec 9. PMID: 25574128

Viscoli CM, Brass LM, Carolei A, Conwit R, Ford GA, Furie KL, Gorman M, Guarino PD, Inzucchi SE, Lovejoy AM, Parsons MW, Peduzzi PN, Ringleb PA, Schwartz GG, Spence JD, Tanne D, Young LH, Kernan WN, IRIS Trial investigators.: Pioglitazone for secondary prevention after ischemic stroke and transient ischemic attack: rationale and design of the Insulin Resistance Intervention after Stroke Trial. Am Heart J. 2014 Dec; 2014 Jul 28. PMID: 25458644

Fried TR, O'Leary J, Towle V, Goldstein MK, Trentalange M, Martin DK: Health outcomes associated with polypharmacy in community-dwelling older adults: a systematic review. J Am Geriatr Soc. 2014 Dec. PMID: 25516023

O Hartaigh B, Gaksch M, Kienreich K, Grübler MR, Verheyen N, März W, Tomaschitz A, Gill TM, Pilz S: Associations of daytime, nighttime, and 24-hour heart rate with four distinct markers of inflammation in hypertensive patients: the Styrian Hypertension Study. J Clin Hypertens (Greenwich). 2014 Dec; 2014 Sep 30. PMID: 25266946

Goyal G, Pisani MA, Murphy TE, Araujo KL, Puchalski JT: Advanced diagnostic bronchoscopy using conscious sedation and the laryngeal nerve block: tolerability, thoroughness, and diagnostic yield. Lung. 2014 Dec; 2014 Jun 28. PMID: 24972639

Heffelfinger C, Fragoso CA, Moreno MA, Overton JD, Mottinger JP, Zhao H, Tohme J, Dellaporta SL: Flexible and scalable genotyping-by-sequencing strategies for population studies. BMC Genomics. 2014 Nov 18; 2014 Nov 18. PMID: 25406744

Sun N, Zhao H: Putting things in order. Proc Natl Acad Sci U S A. 2014 Nov 18; 2014 Nov 7. PMID: 25380598

Fried TR, O'Leary J, Towle V, Goldstein MK, Trentelange M, Martin DK: The effects of comorbidity on the benefits and harms of treatment for chronic disease: a systematic review. PLoS One. 2014 Nov 17; 2014 Nov 17. PMID: 25402463

Chung D, Yang C, Li C, Gelernter J, Zhao H: GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation. PLoS Genet. 2014 Nov 13; 2014 Nov 13. PMID: 25393678

Dodson JA, Geda M, Krumholz HM, Lorenze N, Murphy TE, Allore HG, Charpentier P, Tsang SW, Acampora D, Tinetti ME, Gill TM, Chaudhry SI: Design and rationale of the comprehensive evaluation of risk factors in older patients with AMI (SILVER-AMI) study. BMC Health Serv Res. 2014 Nov 5; 2014 Nov 5. PMID: 25370536

Beech RD, Leffert JJ, Lin A, Hong KA, Hansen J, Umlauf S, Mane S, Zhao H, Sinha R: Stress-related alcohol consumption in heavy drinkers correlates with expression of miR-10a, miR-21, and components of the TAR-RNA-binding protein-associated complex. Alcohol Clin Exp Res. 2014 Nov. PMID: 25421511

Zhang H, Wang F, Xu H, Liu Y, Liu J, Zhao H, Gelernter J: Differentially co-expressed genes in postmortem prefrontal cortex of individuals with alcohol use disorders: influence on alcohol metabolism-related pathways. Hum Genet. 2014 Nov; 2014 Jul 30. PMID: 25073604

Walke LM, Rosenthal RA, Trentalange M, Perkal MF, Maiaroto M, Jeffery SM, Marottoli RA: Restructuring care for older adults undergoing surgery: preliminary data from the Co-Management of Older Operative Patients En Route Across Treatment Environments (CO-OPERATE) model of care. J Am Geriatr Soc. 2014 Nov; 2014 Nov 4. PMID: 25369755

Tinetti ME, Han L, McAvay GJ: Risks and benefits of antihypertensive medications in older adults--reply. JAMA Intern Med. 2014 Nov. PMID: 25365161

Hou L, Ma T, Zhao H: Incorporating functional annotation information in prioritizing disease associated SNPs from genome wide association studies. Sci China Life Sci. 2014 Nov; 2014 Oct 17. PMID: 25326070

Juthani-Mehta M, Datunashvili A, Tinetti M: Tests for urinary tract infection in nursing home residents. JAMA. 2014 Oct 22-29. PMID: 25335152

O'Hartaigh B, Pahor M, Buford TW, Dodson JA, Forman DE, Gill TM, LIFE Study Group.: Physical activity and resting pulse rate in older adults: findings from a randomized controlled trial. Am Heart J. 2014 Oct; 2014 Jul 30. PMID: 25262271

Graham-Steed TR, Soulos PR, Dearing N, Concato J, Tinetti ME, Gross CP: Development and validation of a prognostic index for fracture risk in older men undergoing prostate cancer treatment. J Geriatr Oncol. 2014 Oct 1; 2014 Sep 18. PMID: 25240918

Malinis MF, Chen S, Allore HG, Quagliarello VJ: Outcomes among older adult liver transplantation recipients in the model of end stage liver disease (MELD) era. Ann Transplant. 2014 Sep 26; 2014 Sep 26. PMID: 25256592

Della-Morte D, Wang L, Beecham A, Blanton SH, Zhao H, Sacco RL, Rundek T, Dong C: Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics. J Neurol Sci. 2014 Sep 15; 2014 Jun 14. PMID: 24954085

Xie P, Kranzler HR, Krystal JH, Farrer LA, Zhao H, Gelernter J: Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence. Addict Biol. 2014 Sep; 2013 Jul 16. PMID: 23855403

Zhang H, Wang F, Kranzler HR, Yang C, Xu H, Wang Z, Zhao H, Gelernter J: Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes. Hum Genet. 2014 Sep; 2014 Jun 3. PMID: 24889829

Case SM, O'Leary J, Kim N, Tinetti ME, Fried TR: Relationship between universal health outcome priorities and willingness to take medication for primary prevention of myocardial infarction. J Am Geriatr Soc. 2014 Sep; 2014 Aug 22. PMID: 25146885

Vaz Fragoso CA, Hsu FC, Brinkley T, Church T, Liu CK, Manini T, Newman AB, Stafford RS, McDermott MM, Gill TM, LIFE Study Group.: Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations. J Am Med Dir Assoc. 2014 Sep; 2014 Jun 25. PMID: 24973990

Li B, Chun H, Zhao H: On an Additive Semigraphoid Model for Statistical Networks With Application to Pathway Analysis. J Am Stat Assoc. 2014 Sep. PMID: 26401064

Ó Hartaigh B, Gill TM, Shah I, Hughes AD, Deanfield JE, Kuh D, Hardy R: Association between resting heart rate across the life course and all-cause mortality: longitudinal findings from the Medical Research Council (MRC) National Survey of Health and Development (NSHD). J Epidemiol Community Health. 2014 Sep; 2014 May 21. PMID: 24850484

Sink KM, Espeland MA, Rushing J, Castro CM, Church TS, Cohen R, Gill TM, Henkin L, Jennings JM, Kerwin DR, Manini TM, Myers V, Pahor M, Reid KF, Woolard N, Rapp SR, Williamson JD, LIFE Investigators.: The LIFE Cognition Study: design and baseline characteristics. Clin Interv Aging. 2014 Aug 27; 2014 Aug 27. PMID: 25210447

Zapata HJ, Shaw AC: Aging of the human innate immune system in HIV infection. Curr Opin Immunol. 2014 Aug; 2014 Jul 2. PMID: 24997358

Gill TM: Disentangling the disabling process: insights from the precipitating events project. Gerontologist. 2014 Aug. PMID: 25035454

Lin H, Han L, Peduzzi PN, Murphy TE, Gill TM, Allore HG: A dynamic trajectory class model for intensive longitudinal categorical outcome. Stat Med. 2014 Jul 10; 2014 Feb 11. PMID: 24519416

Ryslik GA, Cheng Y, Cheung KH, Bjornson RD, Zelterman D, Modis Y, Zhao H: A spatial simulation approach to account for protein structure when identifying non-random somatic mutations. BMC Bioinformatics. 2014 Jul 3; 2014 Jul 3. PMID: 24990767

Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H, Farrer LA: Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry. 2014 Jul 1; 2013 Oct 19. PMID: 24143882

Amjad H, Towle V, Fried T: Association of experience with illness and end-of-life care with advance care planning in older adults. J Am Geriatr Soc. 2014 Jul; 2014 Jun 16. PMID: 24934237

Buurman BM, Trentalange M, Nicholson NR, McGloin JM, Gahbauer EA, Allore HG, Gill TM: Residential relocations among older people over the course of more than 10 years. J Am Med Dir Assoc. 2014 Jul; 2014 May 1. PMID: 24794829

Thomas JM, O'Leary JR, Fried TR: A comparison of the willingness of resident and attending physicians to comply with the requests of patients at the end of life. J Gen Intern Med. 2014 Jul; 2014 Mar 20. PMID: 24647724

Lipska KJ, Ross JS, Wang Y, Inzucchi SE, Minges K, Karter AJ, Huang ES, Desai MM, Gill TM, Krumholz HM: National trends in US hospital admissions for hyperglycemia and hypoglycemia among Medicare beneficiaries, 1999 to 2011. JAMA Intern Med. 2014 Jul. PMID: 24838229

Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD, LIFE study investigators.: Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014 Jun 18. PMID: 24866862

Yang C, Li C, Chen M, Chen X, Hou L, Zhao H: A penalized linear mixed model for genomic prediction using pedigree structures. BMC Proc. 2014 Jun 17; 2014 Jun 17. PMID: 25519399

Li C, Yang C, Chen M, Chen X, Hou L, Zhao H: Adjustment of familial relatedness in association test for rare variants. BMC Proc. 2014 Jun 17; 2014 Jun 17. PMID: 25519384

Chen M, Yang C, Li C, Hou L, Chen X, Zhao H: Admixture mapping analysis in the context of GWAS with GAW18 data. BMC Proc. 2014 Jun 17; 2014 Jun 17. PMID: 25519317

Zhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Lee CG, Elias JA, Herzog EL: Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis. Sci Transl Med. 2014 Jun 11. PMID: 24920662

Chung LM, Colangelo CM, Zhao H: Data Pre-Processing for Label-Free Multiple Reaction Monitoring (MRM) Experiments. Biology (Basel). 2014 Jun 5; 2014 Jun 5. PMID: 24905083

Vaz Fragoso CA, Miller ME, Fielding RA, King AC, Kritchevsky SB, McDermott MM, Myers V, Newman AB, Pahor M, Gill TM, Lifestyle Interventions and Independence in Elder Study Group.: Sleep-wake disturbances in sedentary community-dwelling elderly adults with functional limitations. J Am Geriatr Soc. 2014 Jun; 2014 Jun 2. PMID: 24889836

Kookoolis AS, Puchalski JT, Murphy TE, Araujo KL, Pisani MA: Mortality of Hospitalized Patients with Pleural Effusions. J Pulm Respir Med. 2014 Jun. PMID: 25977841

Nish SA, Schenten D, Wunderlich FT, Pope SD, Gao Y, Hoshi N, Yu S, Yan X, Lee HK, Pasman L, Brodsky I, Yordy B, Zhao H, Brüning J, Medzhitov R: T cell-intrinsic role of IL-6 signaling in primary and memory responses. Elife. 2014 May 19; 2014 May 19. PMID: 24842874

Hou L, Chen M, Zhang CK, Cho J, Zhao H: Guilt by rewiring: gene prioritization through network rewiring in genome wide association studies. Hum Mol Genet. 2014 May 15; 2013 Dec 30. PMID: 24381306

Zhu R, Zhao H, Ma S: Identifying gene-environment and gene-gene interactions using a progressive penalization approach. Genet Epidemiol. 2014 May; 2014 Apr 10. PMID: 24723356

Li C, Yang C, Gelernter J, Zhao H: Improving genetic risk prediction by leveraging pleiotropy. Hum Genet. 2014 May; 2013 Dec 13. PMID: 24337655

Yang C, Li C, Kranzler HR, Farrer LA, Zhao H, Gelernter J: Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. Hum Genet. 2014 May; 2013 Dec 3. PMID: 24297757

Gupta AR, Pirruccello M, Cheng F, Kang HJ, Fernandez TV, Baskin JM, Choi M, Liu L, Ercan-Sencicek AG, Murdoch JD, Klei L, Neale BM, Franjic D, Daly MJ, Lifton RP, De Camilli P, Zhao H, Sestan N, State MW: Rare deleterious mutations of the gene EFR3A in autism spectrum disorders. Mol Autism. 2014 Apr 29; 2014 Apr 29. PMID: 24860643

Mannam P, Shinn AS, Srivastava A, Neamu RF, Walker WE, Bohanon M, Merkel J, Kang MJ, Dela Cruz CS, Ahasic AM, Pisani MA, Trentalange M, West AP, Shadel GS, Elias JA, Lee PJ: MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2014 Apr 1; 2014 Jan 31. PMID: 24487387

Vaz Fragoso CA, Beavers DP, Hankinson JL, Flynn G, Berra K, Kritchevsky SB, Liu CK, McDermott MM, Manini TM, Rejeski WJ, Gill TM, Lifestyle Interventions Independence for Elders Study Investigators.: Respiratory impairment and dyspnea and their associations with physical inactivity and mobility in sedentary community-dwelling older persons. J Am Geriatr Soc. 2014 Apr; 2014 Mar 17. PMID: 24635756

Tinetti ME, Han L, Lee DS, McAvay GJ, Peduzzi P, Gross CP, Zhou B, Lin H: Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults. JAMA Intern Med. 2014 Apr. PMID: 24567036

Ryslik GA, Cheng Y, Cheung KH, Modis Y, Zhao H: A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations. BMC Bioinformatics. 2014 Mar 26; 2014 Mar 26. PMID: 24669769

Sauler M, Leng L, Trentalange M, Haslip M, Shan P, Piecychna M, Zhang Y, Andrews N, Mannam P, Allore H, Fried T, Bucala R, Lee PJ: Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15; 2014 Jan 17. PMID: 24441872

Tinetti ME, Han L, McAvay GJ, Lee DS, Peduzzi P, Dodson JA, Gross CP, Zhou B, Lin H: Anti-hypertensive medications and cardiovascular events in older adults with multiple chronic conditions. PLoS One. 2014 Mar 10; 2014 Mar 10. PMID: 24614535

de Rekeneire N, Leo-Summers L, Han L, Gill TM: Epidemiology of restricting fatigue in older adults: the precipitating events project. J Am Geriatr Soc. 2014 Mar; 2014 Feb 11. PMID: 24512073

Tinetti ME: The gap between clinical trials and the real world: extrapolating treatment effects from younger to older adults. JAMA Intern Med. 2014 Mar. PMID: 24424303

Lee DS, Markwardt S, McAvay GJ, Gross CP, Goeres LM, Han L, Peduzzi P, Lin H, Dodson JA, Tinetti ME: Effect of β-blockers on cardiac and pulmonary events and death in older adults with cardiovascular disease and chronic obstructive pulmonary disease. Med Care. 2014 Mar. PMID: 24561758

Tinetti ME, Basu J: Research on multiple chronic conditions: where we are and where we need to go. Med Care. 2014 Mar. PMID: 24561755

Erekson EA, Martin DK, Brousseau EC, Yip SO, Fried TR: Over-the-counter treatments and perineal hygiene in postmenopausal women. Menopause. 2014 Mar. PMID: 23880795

Li D, Sulovari A, Cheng C, Zhao H, Kranzler HR, Gelernter J: Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder. Neuropsychopharmacology. 2014 Mar; 2013 Oct 18. PMID: 24136292

Lorgunpai SJ, Grammas M, Lee DS, McAvay G, Charpentier P, Tinetti ME: Potential therapeutic competition in community-living older adults in the U.S.: use of medications that may adversely affect a coexisting condition. PLoS One. 2014 Feb 25; 2014 Feb 25. PMID: 24586786

Reuben DB, Tinetti ME: The hospital-dependent patient. N Engl J Med. 2014 Feb 20. PMID: 24552316

Qian F, Guo X, Wang X, Yuan X, Chen S, Malawista SE, Bockenstedt LK, Allore HG, Montgomery RR: Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging. Aging (Albany NY). 2014 Feb. PMID: 24595889

Brummel NE, Jackson JC, Pandharipande PP, Thompson JL, Shintani AK, Dittus RS, Gill TM, Bernard GR, Ely EW, Girard TD: Delirium in the ICU and subsequent long-term disability among survivors of mechanical ventilation. Crit Care Med. 2014 Feb. PMID: 24158172

Brown JE, Evans BR, Zheng W, Obas V, Barrera-Martinez L, Egizi A, Zhao H, Caccone A, Powell JR: Human impacts have shaped historical and recent evolution in Aedes aegypti, the dengue and yellow fever mosquito. Evolution. 2014 Feb; 2013 Oct 23. PMID: 24111703

Assis DN, Leng L, Du X, Zhang CK, Grieb G, Merk M, Garcia AB, McCrann C, Chapiro J, Meinhardt A, Mizue Y, Nikolic-Paterson DJ, Bernhagen J, Kaplan MM, Zhao H, Boyer JL, Bucala R: The role of macrophage migration inhibitory factor in autoimmune liver disease. Hepatology. 2014 Feb; 2013 Dec 20. PMID: 23913513

Juthani-Mehta M, Guo X, Shaw AC, Towle V, Ning Y, Wang X, Allore HG, Fikrig E, Montgomery RR: Innate Immune Responses in the Neutrophils of Community Dwelling and Nursing Home Elders. J Aging Sci. 2014 Jan 27. PMID: 25750929

Schenten D, Nish SA, Yu S, Yan X, Lee HK, Brodsky I, Pasman L, Yordy B, Wunderlich FT, Brüning JC, Zhao H, Medzhitov R: Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells. Immunity. 2014 Jan 16. PMID: 24439266

Xu F, Li L, Schulz VP, Gallagher PG, Xiang B, Zhao H, Li P: Cytogenomic mapping and bioinformatic mining reveal interacting brain expressed genes for intellectual disability. Mol Cytogenet. 2014 Jan 10; 2014 Jan 10. PMID: 24410907

Wang L, Rundek T, Beecham A, Hudson B, Blanton SH, Zhao H, Sacco RL, Dong C: Genome-wide interaction study identifies RCBTB1 as a modifier for smoking effect on carotid intima-media thickness. Arterioscler Thromb Vasc Biol. 2014 Jan; 2013 Nov 7. PMID: 24202307

Kim M, Chen X, Chin LJ, Paranjape T, Speed WC, Kidd KK, Zhao H, Weidhaas JB, Slack FJ: Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases. Cell Cycle. 2014; 2014 Feb 3. PMID: 24552817

Lee N, Shin MS, Kang KS, Yoo SA, Mohanty S, Montgomery RR, Shaw AC, Kang I: Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling. Clin Immunol. 2014 May-Jun; 2014 Mar 19. PMID: 24657713

Knauert MP, Yaggi HK, Redeker NS, Murphy TE, Araujo KL, Pisani MA: Feasibility study of unattended polysomnography in medical intensive care unit patients. Heart Lung. 2014 Sep-Oct; 2014 Jul 12. PMID: 25023504

Makris UE, Fraenkel L, Han L, Leo-Summers L, Gill TM: Risk factors for restricting back pain in older persons. J Am Med Dir Assoc. 2014 Jan; 2013 Nov 15. PMID: 24239445

Murphy TE, Baker DI, Leo-Summers LS, Tinetti ME: Trends in Fall-Related Traumatic Brain Injury among Older Persons in Connecticut from 2000-2007. J Gerontol Geriatr Res. 2014. PMID: 25558438

Bastian LA, Trentalange M, Murphy TE, Brandt C, Bean-Mayberry B, Maisel NC, Wright SM, Gaetano VS, Allore H, Skanderson M, Reyes-Harvey E, Yano EM, Rose D, Haskell S: Association between women veterans' experiences with VA outpatient health care and designation as a women's health provider in primary care clinics. Womens Health Issues. 2014 Nov-Dec; 2014 Oct 28. PMID: 25442706

Chun H, Chen M, Li B, Zhao H: Joint conditional Gaussian graphical models with multiple sources of genomic data. Front Genet. 2013 Dec 17; 2013 Dec 17. PMID: 24381584

Panda A, Chen S, Shaw AC, Allore HG: Statistical approaches for analyzing immunologic data of repeated observations: a practical guide. J Immunol Methods. 2013 Dec 15; 2013 Sep 18. PMID: 24055129

Bikdeli B, Wang Y, Kim N, Desai MM, Quagliarello V, Krumholz HM: Trends in hospitalization rates and outcomes of endocarditis among Medicare beneficiaries. J Am Coll Cardiol. 2013 Dec 10; 2013 Aug 28. PMID: 23994421

Hou L, Zhao H: A review of post-GWAS prioritization approaches. Front Genet. 2013 Dec 9; 2013 Dec 9. PMID: 24367376

Han S, Yang BZ, Kranzler HR, Liu X, Zhao H, Farrer LA, Boerwinkle E, Potash JB, Gelernter J: Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. Am J Hum Genet. 2013 Dec 5; 2013 Nov 21. PMID: 24268660

Shaw AC, Goldstein DR, Montgomery RR: Age-dependent dysregulation of innate immunity. Nat Rev Immunol. 2013 Dec; 2013 Oct 25. PMID: 24157572

Fried LF, Emanuele N, Zhang JH, Brophy M, Conner TA, Duckworth W, Leehey DJ, McCullough PA, O'Connor T, Palevsky PM, Reilly RF, Seliger SL, Warren SR, Watnick S, Peduzzi P, Guarino P, VA NEPHRON-D Investigators.: Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med. 2013 Nov 14; 2013 Nov 9. PMID: 24206457

Chen M, Gunel M, Zhao H: SomatiCA: identifying, characterizing and quantifying somatic copy number aberrations from cancer genome sequencing data. PLoS One. 2013 Nov 12; 2013 Nov 12. PMID: 24265680

Xie P, Kranzler HR, Yang C, Zhao H, Farrer LA, Gelernter J: Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry. 2013 Nov 1; 2013 May 28. PMID: 23726511

Zhang S, Zhao H: Normalized modularity optimization method for community identification with degree adjustment. Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Nov; 2013 Nov 4. PMID: 24329313

Gill TM, Murphy TE, Gahbauer EA, Allore HG: The course of disability before and after a serious fall injury. JAMA Intern Med. 2013 Oct 28. PMID: 23958741

Bruvik FK, Allore HG, Ranhoff AH, Engedal K: The effect of psychosocial support intervention on depression in patients with dementia and their family caregivers: an assessor-blinded randomized controlled trial. Dement Geriatr Cogn Dis Extra. 2013 Oct 26; 2013 Oct 26. PMID: 24348500

Dharmarajan K, Strait KM, Lagu T, Lindenauer PK, Tinetti ME, Lynn J, Li SX, Krumholz HM: Acute decompensated heart failure is routinely treated as a cardiopulmonary syndrome. PLoS One. 2013 Oct 21; 2013 Oct 21. PMID: 24250751

Gao Y, Nish SA, Jiang R, Hou L, Licona-Limón P, Weinstein JS, Zhao H, Medzhitov R: Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity. 2013 Oct 17; 2013 Sep 26. PMID: 24076050

Murphy TE, Baker DI, Leo-Summers LS, Allore HG, Tinetti ME: Association between treatment or usual care region and hospitalization for fall-related traumatic brain injury in the Connecticut Collaboration for Fall Prevention. J Am Geriatr Soc. 2013 Oct; 2013 Sep 19. PMID: 24083593

Vaz Fragoso CA, Van Ness PH, Araujo KL, Iannone LP, Marottoli RA: Sleep disturbances and driving practices of older drivers. J Am Geriatr Soc. 2013 Oct; 2013 Sep 3. PMID: 24001143

Fodeh SJ, Lazenby M, Bai M, Ercolano E, Murphy T, McCorkle R: Functional impairments as symptoms in the symptom cluster analysis of patients newly diagnosed with advanced cancer. J Pain Symptom Manage. 2013 Oct; 2013 Feb 4. PMID: 23380336

Dziura JD, Post LA, Zhao Q, Fu Z, Peduzzi P: Strategies for dealing with missing data in clinical trials: from design to analysis. Yale J Biol Med. 2013 Sep 20; 2013 Sep 20. PMID: 24058309

Chaudhry SI, Murphy TE, Gahbauer E, Sussman LS, Allore HG, Gill TM: Restricting symptoms in the last year of life: a prospective cohort study. JAMA Intern Med. 2013 Sep 9. PMID: 23836056

Pisani MA, Bramley K, Vest MT, Akgün KM, Araujo KL, Murphy TE: Patterns of opiate, benzodiazepine, and antipsychotic drug dosing in older patients in a medical intensive care unit. Am J Crit Care. 2013 Sep. PMID: 23996429

Chen X, Slack FJ, Zhao H: Joint analysis of expression profiles from multiple cancers improves the identification of microRNA-gene interactions. Bioinformatics. 2013 Sep 1; 2013 Jun 14. PMID: 23772050

Erekson EA, Yip SO, Wedderburn TS, Martin DK, Li FY, Choi JN, Kenton KS, Fried TR: The Vulvovaginal Symptoms Questionnaire: a questionnaire for measuring vulvovaginal symptoms in postmenopausal women. Menopause. 2013 Sep. PMID: 23481118

Gill TM, Murphy TE, Gahbauer EA, Allore HG: Association of injurious falls with disability outcomes and nursing home admissions in community-living older persons. Am J Epidemiol. 2013 Aug 1; 2013 Apr 1. PMID: 23548756

Puchalski JT, Argento AC, Murphy TE, Araujo KL, Pisani MA: The safety of thoracentesis in patients with uncorrected bleeding risk. Ann Am Thorac Soc. 2013 Aug. PMID: 23952852

Case SM, Towle VR, Fried TR: Considering the balance: development of a scale to assess patient views on trade-offs in competing health outcomes. J Am Geriatr Soc. 2013 Aug; 2013 Jul 19. PMID: 23869795

Gancayco J, Soulos PR, Khiani V, Cramer LD, Ross JS, Genao I, Tinetti M, Gross CP: Age-based and sex-based disparities in screening colonoscopy use among medicare beneficiaries. J Clin Gastroenterol. 2013 Aug. PMID: 23619827

Horwitz LI, Jenq GY, Brewster UC, Chen C, Kanade S, Van Ness PH, Araujo KL, Ziaeian B, Moriarty JP, Fogerty RL, Krumholz HM: Comprehensive quality of discharge summaries at an academic medical center. J Hosp Med. 2013 Aug; 2013 Mar 22. PMID: 23526813

Qian F, Chung L, Zheng W, Bruno V, Alexander RP, Wang Z, Wang X, Kurscheid S, Zhao H, Fikrig E, Gerstein M, Snyder M, Montgomery RR: Identification of genes critical for resistance to infection by West Nile virus using RNA-Seq analysis. Viruses. 2013 Jul 8; 2013 Jul 8. PMID: 23881275

Saxe JP, Chen M, Zhao H, Lin H: Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J. 2013 Jul 3; 2013 May 28. PMID: 23714778

Zhang CK, Hewett J, Hemming J, Grant T, Zhao H, Abraham C, Oikonomou I, Kanakia M, Cho JH, Proctor DD: The influence of depression on quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2013 Jul. PMID: 23669400

Juthani-Mehta M, De Rekeneire N, Allore H, Chen S, O'Leary JR, Bauer DC, Harris TB, Newman AB, Yende S, Weyant RJ, Kritchevsky S, Quagliarello V, Health ABC Study.: Modifiable risk factors for pneumonia requiring hospitalization of community-dwelling older adults: the Health, Aging, and Body Composition Study. J Am Geriatr Soc. 2013 Jul; 2013 Jun 17. PMID: 23772872

Botoseneanu A, Allore HG, Gahbauer EA, Gill TM: Long-term trajectories of lower extremity function in older adults: estimating gender differences while accounting for potential mortality bias. J Gerontol A Biol Sci Med Sci. 2013 Jul; 2012 Nov 16. PMID: 23160367

Ma H, Zhao H: Drug target inference through pathway analysis of genomics data. Adv Drug Deliv Rev. 2013 Jun 30; 2013 Jan 28. PMID: 23369829

Tinetti M: ACP Journal Club. Review: acute geriatric unit care reduces falls, delirium, and functional decline. Ann Intern Med. 2013 Jun 18. PMID: 23778923

Zhang H, Wang F, Kranzler HR, Zhao H, Gelernter J: Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls. PLoS One. 2013; 2013 Jun 14. PMID: 23799031

Ryslik GA, Cheng Y, Cheung KH, Modis Y, Zhao H: Utilizing protein structure to identify non-random somatic mutations. BMC Bioinformatics. 2013 Jun 13; 2013 Jun 13. PMID: 23758891

Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, Romano-Adesman A, Bjornson RD, Breitbart RE, Brown KK, Carriero NJ, Cheung YH, Deanfield J, DePalma S, Fakhro KA, Glessner J, Hakonarson H, Italia MJ, Kaltman JR, Kaski J, Kim R, Kline JK, Lee T, Leipzig J, Lopez A, Mane SM, Mitchell LE, Newburger JW, Parfenov M, Pe'er I, Porter G, Roberts AE, Sachidanandam R, Sanders SJ, Seiden HS, State MW, Subramanian S, Tikhonova IR, Wang W, Warburton D, White PS, Williams IA, Zhao H, Seidman JG, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Seidman CE, Lifton RP: De novo mutations in histone-modifying genes in congenital heart disease. Nature. 2013 Jun 13; 2013 May 12. PMID: 23665959

Tinetti ME, Basch E: Patients' responsibility to participate in decision making and research. JAMA. 2013 Jun 12. PMID: 23700165

Walke LM, Tinetti ME: ACE, MACE, and GRACE: time to put the pieces together: comment on "effects of an acute care for elders unit on costs and 30-day readmissions". JAMA Intern Med. 2013 Jun 10. PMID: 23608885

Akgün KM, Tate JP, Pisani M, Fried T, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K: Medical ICU admission diagnoses and outcomes in human immunodeficiency virus-infected and virus-uninfected veterans in the combination antiretroviral era. Crit Care Med. 2013 Jun. PMID: 23507717

Ferguson J, Wheeler W, Fu Y, Prokunina-Olsson L, Zhao H, Sampson J: Statistical tests for detecting associations with groups of genetic variants: generalization, evaluation, and implementation. Eur J Hum Genet. 2013 Jun; 2012 Oct 24. PMID: 23092956

Murphy TE, Baker DI, Leo-Summers LS, Bianco L, Gottschalk M, Acampora D, King MB: Integration of fall prevention into state policy in Connecticut. Gerontologist. 2013 Jun; 2012 Oct 4. PMID: 23042690

Thomas JM, Cooney LM Jr, Fried TR: Systematic review: Health-related characteristics of elderly hospitalized adults and nursing home residents associated with short-term mortality. J Am Geriatr Soc. 2013 Jun; 2013 May 20. PMID: 23692412

Fodeh SJ, Brandt C, Luong TB, Haddad A, Schultz M, Murphy T, Krauthammer M: Complementary ensemble clustering of biomedical data. J Biomed Inform. 2013 Jun; 2013 Feb 27. PMID: 23454721

Kang KS, Lee N, Shin MS, Kim SD, Yu Y, Mohanty S, Belshe RB, Montgomery RR, Shaw AC, Kang I: An altered relationship of influenza vaccine-specific IgG responses with T cell immunity occurs with aging in humans. Clin Immunol. 2013 May; 2013 Mar 15. PMID: 23578549

Horwitz LI, Dombroski J, Murphy TE, Farnan JM, Johnson JK, Arora VM: Validation of a handoff assessment tool: the Handoff CEX. J Clin Nurs. 2013 May; 2012 Jun 7. PMID: 22671983

Yang C, Wang L, Zhang S, Zhao H: Accounting for non-genetic factors by low-rank representation and sparse regression for eQTL mapping. Bioinformatics. 2013 Apr 15; 2013 Feb 17. PMID: 23419377

Gill TM, Gahbauer EA, Lin H, Han L, Allore HG: Comparisons between older men and women in the trajectory and burden of disability over the course of nearly 14 years. J Am Med Dir Assoc. 2013 Apr; 2013 Jan 4. PMID: 23294968

Horwitz LI, Rand D, Staisiunas P, Van Ness PH, Araujo KL, Banerjee SS, Farnan JM, Arora VM: Development of a handoff evaluation tool for shift-to-shift physician handoffs: the Handoff CEX. J Hosp Med. 2013 Apr. PMID: 23559502

Pietrzak RH, Van Ness PH, Fried TR, Galea S, Norris FH: Trajectories of posttraumatic stress symptomatology in older persons affected by a large-magnitude disaster. J Psychiatr Res. 2013 Apr; 2013 Jan 4. PMID: 23290559

Case SM, Fried TR, O'Leary J: How to ask: older adults' preferred tools in health outcome prioritization. Patient Educ Couns. 2013 Apr; 2012 Dec 4. PMID: 23218242

Chung LM, Ferguson JP, Zheng W, Qian F, Bruno V, Montgomery RR, Zhao H: Differential expression analysis for paired RNA-Seq data. BMC Bioinformatics. 2013 Mar 27; 2013 Mar 27. PMID: 23530607

Zheng W, Zhao H: Studying the evolution of transcription factor binding events using multi-species ChIP-Seq data. Stat Appl Genet Mol Biol. 2013 Mar 26; 2013 Mar 26. PMID: 23446869

Falzer PR, Leventhal HL, Peters E, Fried TR, Kerns R, Michalski M, Fraenkel L: The practitioner proposes a treatment change and the patient declines: what to do next? Pain Pract. 2013 Mar; 2012 Jul 2. PMID: 23462141

Chaudhry SI, McAvay G, Chen S, Whitson H, Newman AB, Krumholz HM, Gill TM: Risk factors for hospital admission among older persons with newly diagnosed heart failure: findings from the Cardiovascular Health Study. J Am Coll Cardiol. 2013 Feb 12. PMID: 23391194

Han L, Allore H, Murphy T, Gill T, Peduzzi P, Lin H: Dynamics of functional aging based on latent-class trajectories of activities of daily living. Ann Epidemiol. 2013 Feb. PMID: 23305692

Qian F, Bolen CR, Jing C, Wang X, Zheng W, Zhao H, Fikrig E, Bruce RD, Kleinstein SH, Montgomery RR: Impaired toll-like receptor 3-mediated immune responses from macrophages of patients chronically infected with hepatitis C virus. Clin Vaccine Immunol. 2013 Feb; 2012 Dec 5. PMID: 23220997

Puchalski JT, Argento AC, Murphy TE, Araujo KL, Oliva IB, Rubinowitz AN, Pisani MA: Etiologies of bilateral pleural effusions. Respir Med. 2013 Feb; 2012 Dec 7. PMID: 23219348

Reilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA, Herzog EL: Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis. Am J Respir Crit Care Med. 2013 Jan 15; 2012 Dec 6. PMID: 23220917

Zhang H, Herman AI, Kranzler HR, Anton RF, Zhao H, Zheng W, Gelernter J: Array-based profiling of DNA methylation changes associated with alcohol dependence. Alcohol Clin Exp Res. 2013 Jan; 2012 Aug 24. PMID: 22924764

Vaz Fragoso CA, Gill TM, McAvay G, Quanjer PH, Van Ness PH, Concato J: Respiratory impairment in older persons: when less means more. Am J Med. 2013 Jan; 2012 Nov 20. PMID: 23177541

Lin H, Allore HG, McAvay G, Tinetti ME, Gill TM, Gross CP, Murphy TE: A method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome. Am J Public Health. 2013 Jan; 2012 Apr 19. PMID: 22515873

Ning Y, McAvay G, Chaudhry SI, Arnold AM, Allore HG: Results differ by applying distinctive multiple imputation approaches on the longitudinal cardiovascular health study data. Exp Aging Res. 2013. PMID: 23316735

Ferguson JP, Cho JH, Yang C, Zhao H: Empirical Bayes correction for the Winner's Curse in genetic association studies. Genet Epidemiol. 2013 Jan; 2012 Sep 25. PMID: 23012258

Allore HG, Ning Y, Brandt CA, Goulet JL: Accounting for the Hierarchical Structure in Veterans Health Administration Data: Differences in Healthcare Utilization between Men and Women Veterans. Int J Stat Med Res. 2013. PMID: 24910720

Akgün KM, Gordon K, Pisani M, Fried T, McGinnis KA, Tate JP, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K: Risk factors for hospitalization and medical intensive care unit (MICU) admission among HIV-infected Veterans. J Acquir Immune Defic Syndr. 2013 Jan 1. PMID: 23111572

Cone DC, Ahern J, Lee CH, Baker D, Murphy T, Bogucki S: A descriptive study of the "lift-assist" call. Prehosp Emerg Care. 2013 Jan-Mar; 2012 Sep 12. PMID: 22971148