Pepper Center Publications

Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM: Factors Associated with Functional Recovery Among Older ICU Survivors. Am J Respir Crit Care Med. 2016 Feb 3; 2016 Feb 3. PMID: 26840348

Gill TM, Pahor M, Guralnik JM, McDermott MM, King AC, Buford TW, Strotmeyer ES, Nelson ME, Sink KM, Demons JL, Kashaf SS, Walkup MP, Miller ME, LIFE Study Investigators: Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study). BMJ. 2016 Feb 3; 2016 Feb 3. PMID: 26842425

Huang X, Stern DF, Zhao H: Transcriptional Profiles from Paired Normal Samples Offer Complementary Information on Cancer Patient Survival - Evidence from TCGA Pan-Cancer Data. Sci Rep. 2016 Feb 3; 2016 Feb 3. PMID: 26837275

Fried TR, Redding CA, Robbins ML, Paiva AL, O'Leary JR, Iannone L: Development of Personalized Health Messages to Promote Engagement in Advance Care Planning. J Am Geriatr Soc. 2016 Jan 25; 2016 Jan 25. PMID: 26804791

Fried TR: Shared Decision Making--Finding the Sweet Spot. N Engl J Med. 2016 Jan 14. PMID: 26760081

Wang F, Xu H, Zhao H, Gelernter J, Zhang H: DNA co-methylation modules in postmortem prefrontal cortex tissues of European Australians with alcohol use disorders. Sci Rep. 2016 Jan 14; 2016 Jan 14. PMID: 26763658

Allore HG, Zhan Y, Cohen AB, Tinetti ME, Trentalange M, McAvay G: Methodology to Estimate the Longitudinal Average Attributable Fraction of Guideline-recommended Medications for Death in Older Adults With Multiple Chronic Conditions. J Gerontol A Biol Sci Med Sci. 2016 Jan 8; 2016 Jan 8. PMID: 26748093

Goffredo M, Caprio S, Feldstein AE, D'Adamo E, Shaw MM, Pierpont B, Savoye M, Zhao H, Bale AE, Santoro N: Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study. Hepatology. 2016 Jan; 2015 Nov 16. PMID: 26457389

Johnson MJ, Bland JM, Gahbauer EA, Ekström M, Sinnarajah A, Gill TM, Currow DC: Breathlessness in Elderly Adults During the Last Year of Life Sufficient to Restrict Activity: Prevalence, Pattern, and Associated Factors. J Am Geriatr Soc. 2016 Jan. PMID: 26782854

Ramaswamy A, Homer R, Killam J, Pisani MA, Murphy TE, Araujo K, Puchalski J: Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease. J Bronchology Interv Pulmonol. 2016 Jan. PMID: 26705007

Harvey PD, Aslan M, Du M, Zhao H, Siever LJ, Pulver A, Gaziano JM, Concato J: Factor structure of cognition and functional capacity in two studies of schizophrenia and bipolar disorder: Implications for genomic studies. Neuropsychology. 2016 Jan. PMID: 26710094

Fragoso CA, Heffelfinger C, Zhao H, Dellaporta SL: Imputing Genotypes in Biallelic Populations from Low-Coverage Sequence Data. Genetics. 2015 Dec 29; 2015 Dec 29. PMID: 26715670

Williams GR, Mackenzie A, Magnuson A, Olin R, Chapman A, Mohile S, Allore H, Somerfield MR, Targia V, Extermann M, Cohen HJ, Hurria A, Holmes H: Comorbidity in older adults with cancer. J Geriatr Oncol. 2015 Dec 22; 2015 Dec 22. PMID: 26725537

King AC, Salvo D, Banda JA, Ahn DK, Gill TM, Miller M, Newman AB, Fielding RA, Siordia C, Moore S, Folta S, Spring B, Manini T, Pahor M, LIFE Study Investigators: An observational study identifying obese subgroups among older adults at increased risk of mobility disability: do perceptions of the neighborhood environment matter? Int J Behav Nutr Phys Act. 2015 Dec 18; 2015 Dec 18. PMID: 26684894

Erekson EA, Li FY, Martin DK, Fried TR: Vulvovaginal symptoms prevalence in postmenopausal women and relationship to other menopausal symptoms and pelvic floor disorders. Menopause. 2015 Dec 7; 2015 Dec 7. PMID: 26645820

Li G, Zhao H: M(3)-S: a genotype calling method incorporating information from samples with known genotypes. BMC Bioinformatics. 2015 Dec 3; 2015 Dec 3. PMID: 26634345

Murphy TE, Araujo KL, Pisani MA: The authors reply. Crit Care Med. 2015 Dec. PMID: 26575672

Montgomery RR, Shaw AC: Paradoxical changes in innate immunity in aging: recent progress and new directions. J Leukoc Biol. 2015 Dec; 2015 Jul 17. PMID: 26188078

Buurman BM, Han L, Murphy TE, Gahbauer EA, Leo-Summers L, Allore HG, Gill TM: Trajectories of Disability Among Older Persons Before and After a Hospitalization Leading to a Skilled Nursing Facility Admission. J Am Med Dir Assoc. 2015 Nov 24; 2015 Nov 24. PMID: 26620073

Fragoso CA, McAvay G, Van Ness PH, Casaburi R, Jensen RL, MacIntyre N, Yaggi HK, Gill TM, Concato J: Phenotype of Spirometric Impairment in an Aging Population. Am J Respir Crit Care Med. 2015 Nov 5; 2015 Nov 5. PMID: 26540012

Vaz Fragoso CA, McAvay G, Van Ness PH, Metter EJ, Ferrucci L, Yaggi HK, Concato J, Gill TM: Aging-Related Considerations When Evaluating the Forced Expiratory Volume in 1 Second (FEV1) Over Time. J Gerontol A Biol Sci Med Sci. 2015 Nov 2; 2015 Nov 2. PMID: 26525091

Fraenkel L, Matzko CK, Webb DE, Oppermann B, Charpentier P, Peters E, Reyna V, Newman ED: Use of Decision Support for Improved Knowledge, Values Clarification, and Informed Choice in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2015 Nov. PMID: 26195173

Wang Q, Yang C, Gelernter J, Zhao H: Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS. Hum Genet. 2015 Nov; 2015 Sep 4. PMID: 26340901

Levy BR, Slade MD, Chung PH, Gill TM: Resiliency Over Time of Elders' Age Stereotypes After Encountering Stressful Events. J Gerontol B Psychol Sci Soc Sci. 2015 Nov; 2014 Jul 5. PMID: 24997287

Han L, Gill TM, Jones BL, Allore HG: Cognitive Aging Trajectories and Burdens of Disability, Hospitalization and Nursing Home Admission Among Community-living Older Persons. J Gerontol A Biol Sci Med Sci. 2015 Oct 28; 2015 Oct 28. PMID: 26511011

Lu Q, Yao X, Hu Y, Zhao H: GenoWAP: GWAS signal prioritization through integrated analysis of genomic functional annotation. Bioinformatics. 2015 Oct 25; 2015 Oct 25. PMID: 26504140

Polimanti R, Zhang H, Smith AH, Zhao H, Farrer LA, Kranzler HR, Gelernter J: Genome-wide association study of body mass index in subjects with alcohol dependence. Addict Biol. 2015 Oct 12; 2015 Oct 12. PMID: 26458734

Wu X, Guarino P, Lo AC, Peduzzi P, Wininger M: Long-term Effectiveness of Intensive Therapy in Chronic Stroke. Neurorehabil Neural Repair. 2015 Oct 8; 2015 Oct 8. PMID: 26450442

Wang T, Chen M, Zhao H: Estimating DNA methylation levels by joint modeling of multiple methylation profiles from microarray data. Biometrics. 2015 Oct 4; 2015 Oct 4. PMID: 26433612

Tinetti ME, McAvay G, Trentalange M, Cohen AB, Allore HG: Association between guideline recommended drugs and death in older adults with multiple chronic conditions: population based cohort study. BMJ. 2015 Oct 2; 2015 Oct 2. PMID: 26432468

Vaz Fragoso CA, McAvay G, Van Ness PH, Casaburi R, Jensen RL, MacIntyre N, Gill TM, Yaggi HK, Concato J: Phenotype of normal spirometry in an aging population. Am J Respir Crit Care Med. 2015 Oct 1. PMID: 26114439

Monin JK, Levy B, Chen B, Fried T, Stahl ST, Schulz R, Doyle M, Kershaw T: Husbands' and Wives' Physical Activity and Depressive Symptoms: Longitudinal Findings from the Cardiovascular Health Study. Ann Behav Med. 2015 Oct. PMID: 25868508

Fang H, Huang C, Zhao H, Deng M: CCLasso: correlation inference for compositional data through Lasso. Bioinformatics. 2015 Oct 1; 2015 Jun 4. PMID: 26048598

Shih AF, Buurman BM, Tynan-McKiernan K, Tinetti ME, Jenq G: Views of Primary Care Physicians and Home Care Nurses on the Causes of Readmission of Older Adults. J Am Geriatr Soc. 2015 Oct. PMID: 26480986

Cohen AB, Wright MS, Cooney L Jr, Fried T: Guardianship and End-of-Life Decision Making. JAMA Intern Med. 2015 Oct. PMID: 26258634

Pang H, Kim I, Zhao H: Random Effects Model for Multiple Pathway Analysis with Applications to Type II Diabetes Microarray Data. Stat Biosci. 2015 Oct 1; 2014 Jan 30. PMID: 26640601

Bell SP, Orr NM, Dodson JA, Rich MW, Wenger NK, Blum K, Harold JG, Tinetti ME, Maurer MS, Forman DE: What to Expect From the Evolving Field of Geriatric Cardiology. J Am Coll Cardiol. 2015 Sep 15. PMID: 26361161

Shin MS, You S, Kang Y, Lee N, Yoo SA, Park K, Kang KS, Kim SH, Mohanty S, Shaw AC, Montgomery RR, Hwang D, Kang I: DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine. J Immunol. 2015 Sep 15; 2015 Aug 14. PMID: 26276874

Allore HG, Zhan Y, Tinetti M, Trentalange M, McAvay G: Longitudinal average attributable fraction as a method for studying time-varying conditions and treatments on recurrent self-rated health: the case of medications in older adults with multiple chronic conditions. Ann Epidemiol. 2015 Sep; 2015 May 8. PMID: 26033374

Feder SL, Schulman-Green D, Geda M, Williams K, Dodson JA, Nanna MG, Allore HG, Murphy TE, Tinetti ME, Gill TM, Chaudhry SI: Physicians' perceptions of the Thrombolysis in Myocardial Infarction (TIMI) risk score in older adults with acute myocardial infarction. Heart Lung. 2015 Sep-Oct; 2015 Jul 9. PMID: 26164651

Vaz Fragoso CA, Van Ness PH, Araujo KL, Iannone LP, Klar Yaggi H: Age-Related Differences in Sleep-Wake Symptoms of Adults Undergoing Polysomnography. J Am Geriatr Soc. 2015 Sep. PMID: 26389988

Swerdloff RS, Pak Y, Wang C, Liu PY, Bhasin S, Gill TM, Matsumoto AM, Pahor M, Surampudi P, Snyder PJ: Serum Testosterone (T) Level Variability in T Gel-Treated Older Hypogonadal Men: Treatment Monitoring Implications. J Clin Endocrinol Metab. 2015 Sep; 2015 Jun 29. PMID: 26120790

Cauley JA, Fluharty L, Ellenberg SS, Gill TM, Ensrud KE, Barrett-Connor E, Cifelli D, Cunningham GR, Matsumoto AM, Bhasin S, Pahor M, Farrar JT, Cella D, Rosen RC, Resnick SM, Swerdloff RS, Lewis CE, Molitch ME, Crandall JP, Stephens-Shields AJ, Strorer TW, Wang C, Anton S, Basaria S, Diem S, Tabatabaie V, Dougar D, Hou X, Snyder PJ: Recruitment and Screening for the Testosterone Trials. J Gerontol A Biol Sci Med Sci. 2015 Sep; 2015 Apr 15. PMID: 25878029

Coylewright M, Palmer R, O'Neill ES, Robb JF, Fried TR: Patient-defined goals for the treatment of severe aortic stenosis: a qualitative analysis. Health Expect. 2015 Aug 14; 2015 Aug 14. PMID: 26275070

DeBiasi EM, Pisani MA, Murphy TE, Araujo K, Kookoolis A, Argento AC, Puchalski J: Mortality among patients with pleural effusion undergoing thoracentesis. Eur Respir J. 2015 Aug; 2015 Apr 2. PMID: 25837039

Vaz Fragoso CA, Araujo K, Leo-Summers L, Van Ness PH: Lower Extremity Proximal Muscle Function and Dyspnea in Older Persons. J Am Geriatr Soc. 2015 Aug; 2015 Jul 22. PMID: 26200804

Case SM, O'Leary J, Kim N, Tinetti ME, Fried TR: Older Adults' Recognition of Trade-Offs in Healthcare Decision-Making. J Am Geriatr Soc. 2015 Aug; 2015 Jul 14. PMID: 26173743

Espeland MA, Newman AB, Sink K, Gill TM, King AC, Miller ME, Guralnik J, Katula J, Church T, Manini T, Reid KF, McDermott MM, LIFE Study Group: Associations Between Ankle-Brachial Index and Cognitive Function: Results From the Lifestyle Interventions and Independence for Elders Trial. J Am Med Dir Assoc. 2015 Aug 1; 2015 Apr 11. PMID: 25869993

Cohen AB, Trentalange M, Fried T: Surrogate Decision Making for Patients Without Nuclear Family. JAMA. 2015 Jul 28. PMID: 26219065

Xu K, Kranzler HR, Sherva R, Sartor CE, Almasy L, Koesterer R, Zhao H, Farrer LA, Gelernter J: Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. Alcohol Clin Exp Res. 2015 Jul; 2015 Jun 3. PMID: 26036284

Vaz Fragoso CA, Miller ME, King AC, Kritchevsky SB, Liu CK, Myers VH, Nadkarni NK, Pahor M, Spring BJ, Gill TM, Lifestyle Interventions and Independence for Elders Study Group: Effect of Structured Physical Activity on Sleep-Wake Behaviors in Sedentary Elderly Adults with Mobility Limitations. J Am Geriatr Soc. 2015 Jul; 2015 Jun 26. PMID: 26115386

Gill TM, Allore HG, Gahbauer EA, Han L: Establishing a Hierarchy for the Two Components of Restricted Activity. J Gerontol A Biol Sci Med Sci. 2015 Jul; 2014 Nov 12. PMID: 25391532

Xu X, Liang J, Bennett JM, Botoseneanu A, Allore HG: Socioeconomic stratification and multidimensional health trajectories: evidence of convergence in later old age. J Gerontol B Psychol Sci Soc Sci. 2015 Jul; 2014 Aug 26. PMID: 25161216

Feder SL, Schulman-Green D, Dodson JA, Geda M, Williams Rn K, Nanna MG, Allore HG, Murphy TE, Tinetti ME, Gill TM, Chaudhry SI: Risk Stratification in Older Patients With Acute Myocardial Infarction: Physicians' Perspectives. J Aging Health. 2015 Jun 22; 2015 Jun 22. PMID: 26100619

Brummel NE, Balas MC, Morandi A, Ferrante LE, Gill TM, Ely EW: Understanding and reducing disability in older adults following critical illness. Crit Care Med. 2015 Jun. PMID: 25756418

Lu Q, Hu Y, Sun J, Cheng Y, Cheung KH, Zhao H: A statistical framework to predict functional non-coding regions in the human genome through integrated analysis of annotation data. Sci Rep. 2015 May 27; 2015 May 27. PMID: 26015273

Gill TM, Gahbauer EA, Han L, Allore HG: The role of intervening hospital admissions on trajectories of disability in the last year of life: prospective cohort study of older people. BMJ. 2015 May 20; 2015 May 20. PMID: 25995357

Xie Y, Jin Y, Merenick BL, Ding M, Fetalvero KM, Wagner RJ, Mai A, Gleim S, Tucker DF, Birnbaum MJ, Ballif BA, Luciano AK, Sessa WC, Rzucidlo EM, Powell RJ, Hou L, Zhao H, Hwa J, Yu J, Martin KA: Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition. Sci Signal. 2015 May 12; 2015 May 12. PMID: 25969542

Ahasic AM, Van Ness PH, Murphy TE, Araujo KL, Pisani MA: Functional status after critical illness: agreement between patient and proxy assessments. Age Ageing. 2015 May; 2014 Oct 16. PMID: 25324334

Pisani MA, Araujo KL, Murphy TE: Association of cumulative dose of haloperidol with next-day delirium in older medical ICU patients. Crit Care Med. 2015 May. PMID: 25746748

Erekson EA, Ciarleglio MM, Hanissian PD, Strohbehn K, Bynum JP, Fried TR: Functional disability and compromised mobility among older women with urinary incontinence. Female Pelvic Med Reconstr Surg. 2015 May-Jun. PMID: 25185600

Rejeski WJ, Rushing J, Guralnik JM, Ip EH, King AC, Manini TM, Marsh AP, McDermott MM, Fielding RA, Newman AB, Tudor-Locke C, Gill TM, LIFE Study Group: The MAT-sf: identifying risk for major mobility disability. J Gerontol A Biol Sci Med Sci. 2015 May; 2015 Feb 13. PMID: 25680917

Walker WE, Kurscheid S, Joshi S, Lopez CA, Goh G, Choi M, Barakat L, Francis J, Fisher A, Kozal M, Zapata H, Shaw A, Lifton R, Sutton RE, Fikrig E: Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers. J Virol. 2015 May; 2015 Mar 4. PMID: 25740989

Zheng C, Dalla Man C, Cobelli C, Groop L, Zhao H, Bale AE, Shaw M, Duran E, Pierpont B, Caprio S, Santoro N: A common variant in the MTNR1b gene is associated with increased risk of impaired fasting glucose (IFG) in youth with obesity. Obesity (Silver Spring). 2015 May. PMID: 25919927

Stefani G, Chen X, Zhao H, Slack FJ: A novel mechanism of LIN-28 regulation of let-7 microRNA expression revealed by in vivo HITS-CLIP in C. elegans. RNA. 2015 May; 2015 Mar 24. PMID: 25805859

Zuo L, Zhang CK, Sayward FG, Cheung KH, Wang K, Krystal JH, Zhao H, Luo X: Gene-based and pathway-based genome-wide association study of alcohol dependence. Shanghai Arch Psychiatry. 2015 Apr 25. PMID: 26120261

Makris UE, Higashi RT, Marks EG, Fraenkel L, Sale JE, Gill TM, Reid MC: Ageism, negative attitudes, and competing co-morbidities--why older adults may not seek care for restricting back pain: a qualitative study. BMC Geriatr. 2015 Apr 8; 2015 Apr 8. PMID: 25887905

Cohen AB, Trentalange M, Fried T: Patients with next-of-kin relationships outside the nuclear family. JAMA. 2015 Apr 7. PMID: 25849183

Hartaigh Bó, Allore HG, Trentalange M, McAvay G, Pilz S, Dodson JA, Gill TM: Elevations in time-varying resting heart rate predict subsequent all-cause mortality in older adults. Eur J Prev Cardiol. 2015 Apr; 2014 Jan 20. PMID: 24445263

Zapata HJ, Quagliarello VJ: The microbiota and microbiome in aging: potential implications in health and age-related diseases. J Am Geriatr Soc. 2015 Apr; 2015 Apr 8. PMID: 25851728

Howell BA, Azar MM, Landry ML, Shaw AC: Toscana virus encephalitis in a traveler returning to the United States. J Clin Microbiol. 2015 Apr; 2015 Feb 11. PMID: 25673791

Qi X, Luo R, Carroll RJ, Zhao H: Sparse Regression by Projection and Sparse Discriminant Analysis. J Comput Graph Stat. 2015 Apr 1. PMID: 26345204

Mohanty S, Joshi SR, Ueda I, Wilson J, Blevins TP, Siconolfi B, Meng H, Devine L, Raddassi K, Tsang S, Belshe RB, Hafler DA, Kaech SM, Kleinstein SH, Trentalange M, Allore HG, Shaw AC: Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. J Infect Dis. 2015 Apr 1; 2014 Nov 2. PMID: 25367297

Ferrante LE, Pisani MA, Murphy TE, Gahbauer EA, Leo-Summers LS, Gill TM: Functional trajectories among older persons before and after critical illness. JAMA Intern Med. 2015 Apr. PMID: 25665067

Bean-Mayberry B, Bastian L, Trentalange M, Murphy TE, Skanderson M, Allore H, Reyes-Harvey E, Maisel NC, Gaetano V, Wright S, Haskell S, Brandt C: Associations between provider designation and female-specific cancer screening in women Veterans. Med Care. 2015 Apr. PMID: 25767975

Lam W, Jiang Z, Guan F, Huang X, Hu R, Wang J, Bussom S, Liu SH, Zhao H, Yen Y, Cheng YC: PHY906(KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment. Sci Rep. 2015 Mar 30; 2015 Mar 30. PMID: 25819872

Juthani-Mehta M, Van Ness PH, McGloin J, Argraves S, Chen S, Charpentier P, Miller L, Williams K, Wall D, Baker D, Tinetti M, Peduzzi P, Quagliarello VJ: A cluster-randomized controlled trial of a multicomponent intervention protocol for pneumonia prevention among nursing home elders. Clin Infect Dis. 2015 Mar 15; 2014 Dec 16. PMID: 25520333

Erekson EA, Ciarleglio MM, Hanissian PD, Strohbehn K, Bynum JP, Fried TR: Functional disability among older women with fecal incontinence. Am J Obstet Gynecol. 2015 Mar; 2014 Oct 15. PMID: 25447956

Gelernter J, Kranzler HR, Sherva R, Almasy L, Herman AI, Koesterer R, Zhao H, Farrer LA: Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Biol Psychiatry. 2015 Mar 1; 2014 Sep 16. PMID: 25555482

Ciarleglio MM, Arendt CD, Makuch RW, Peduzzi PN: Selection of the treatment effect for sample size determination in a superiority clinical trial using a hybrid classical and Bayesian procedure. Contemp Clin Trials. 2015 Mar; 2015 Jan 9. PMID: 25583273

Hopper K, Fried TR, Pisani MA: Health care worker attitudes and identified barriers to patient sleep in the medical intensive care unit. Heart Lung. 2015 Mar-Apr; 2015 Feb 14. PMID: 25686516

Madden GR, Argraves SM, Van Ness PH, Juthani-Mehta M: Antibiotic susceptibility of urinary isolates in nursing home residents consuming cranberry capsules versus placebo. Infect Control Hosp Epidemiol. 2015 Mar. PMID: 25695180

Gill TM, Allore HG, Gahbauer EA, Murphy TE: The role of intervening illnesses and injuries in prolonging the disabling process. J Am Geriatr Soc. 2015 Mar; 2015 Mar 4. PMID: 25735396

Gross CP, Fried TR, Tinetti ME, Ross JS, Genao I, Hossain S, Wolf E, Lewis CL: Decision-making and cancer screening: a qualitative study of older adults with multiple chronic conditions. J Geriatr Oncol. 2015 Mar; 2014 Dec 17. PMID: 25544380

Li D, Zhao H, Kranzler HR, Li MD, Jensen KP, Zayats T, Farrer LA, Gelernter J: Genome-wide association study of copy number variations (CNVs) with opioid dependence. Neuropsychopharmacology. 2015 Mar; 2014 Sep 27. PMID: 25345593

Evans BR, Gloria-Soria A, Hou L, McBride C, Bonizzoni M, Zhao H, Powell JR: A Multipurpose, High-Throughput Single-Nucleotide Polymorphism Chip for the Dengue and Yellow Fever Mosquito, Aedes aegypti. G3 (Bethesda). 2015 Feb 26; 2015 Feb 26. PMID: 25721127

Sun J, Zhao H: The application of sparse estimation of covariance matrix to quadratic discriminant analysis. BMC Bioinformatics. 2015 Feb 18; 2015 Feb 18. PMID: 25886892

Botoseneanu A, Ambrosius WT, Beavers DP, de Rekeneire N, Anton S, Church T, Folta SC, Goodpaster BH, King AC, Nicklas BJ, Spring B, Wang X, Gill TM, LIFE Study Groups: Prevalence of metabolic syndrome and its association with physical capacity, disability, and self-rated health in Lifestyle Interventions and Independence for Elders Study participants. J Am Geriatr Soc. 2015 Feb; 2015 Jan 30. PMID: 25645664

Marcus BS, McAvay G, Gill TM, Vaz Fragoso CA: Respiratory symptoms, spirometric respiratory impairment, and respiratory disease in middle-aged and older persons. J Am Geriatr Soc. 2015 Feb; 2015 Jan 30. PMID: 25643966

Cesari M, Vellas B, Hsu FC, Newman AB, Doss H, King AC, Manini TM, Church T, Gill TM, Miller ME, Pahor M, LIFE Study Group: A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study. J Gerontol A Biol Sci Med Sci. 2015 Feb; 2014 Nov 11. PMID: 25387728

Jenq GY, Tinetti ME: Post-acute care: who belongs where? JAMA Intern Med. 2015 Feb. PMID: 25437105

Foxman EF, Storer JA, Fitzgerald ME, Wasik BR, Hou L, Zhao H, Turner PE, Pyle AM, Iwasaki A: Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells. Proc Natl Acad Sci U S A. 2015 Jan 20; 2015 Jan 5. PMID: 25561542

Thakar J, Mohanty S, West AP, Joshi SR, Ueda I, Wilson J, Meng H, Blevins TP, Tsang S, Trentalange M, Siconolfi B, Park K, Gill TM, Belshe RB, Kaech SM, Shadel GS, Kleinstein SH, Shaw AC: Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination. Aging (Albany NY). 2015 Jan. PMID: 25596819

Stabenau HF, Morrison LJ, Gahbauer EA, Leo-Summers L, Allore HG, Gill TM: Functional trajectories in the year before hospice. Ann Fam Med. 2015 Jan-Feb. PMID: 25583890

Rabinowitz PM, Slizovskiy IB, Lamers V, Trufan SJ, Holford TR, Dziura JD, Peduzzi PN, Kane MJ, Reif JS, Weiss TR, Stowe MH: Proximity to natural gas wells and reported health status: results of a household survey in Washington County, Pennsylvania. Environ Health Perspect. 2015 Jan; 2014 Sep 10. PMID: 25204871

Murphy TE, Allore HG, Han L, Peduzzi PN, Gill TM, Xu X, Lin H: A longitudinal, observational study with many repeated measures demonstrated improved precision of individual survival curves using Bayesian joint modeling of disability and survival. Exp Aging Res. 2015. PMID: 25978444

Yang C, Li C, Wang Q, Chung D, Zhao H: Implications of pleiotropy: challenges and opportunities for mining Big Data in biomedicine. Front Genet. 2015; 2015 Jun 30. PMID: 26175753

Wang Q, Lu Q, Zhao H: A review of study designs and statistical methods for genomic epidemiology studies using next generation sequencing. Front Genet. 2015; 2015 Apr 20. PMID: 25941534

Joshi SR, Mohanty S, Shaw AC: Multicolor Digital Flow Cytometry in Human Translational Immunology. Methods Mol Biol. 2015. PMID: 26420708

Polimanti R, Yang C, Zhao H, Gelernter J: Dissecting ancestry genomic background in substance dependence genome-wide association studies. Pharmacogenomics. 2015; 2015 Aug 12. PMID: 26267224

Argento AC, Murphy TE, Pisani MA, Araujo KL, Puchalski J: Patient-Centered Outcomes Following Thoracentesis. Pleura (Thousand Oaks). 2015 Jan-Dec; 2015 Sep 1. PMID: 26767192

Tadeu AM, Lin S, Hou L, Chung L, Zhong M, Zhao H, Horsley V: Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells. PLoS One. 2015; 2015 Apr 7. PMID: 25849374

Ng R, Allore HG, Trentalange M, Monin JK, Levy BR: Increasing negativity of age stereotypes across 200 years: evidence from a database of 400 million words. PLoS One. 2015; 2015 Feb 12. PMID: 25675438

Bann D, Hire D, Manini T, Cooper R, Botoseneanu A, McDermott MM, Pahor M, Glynn NW, Fielding R, King AC, Church T, Ambrosius WT, Gill TM, LIFE Study Group: Light Intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study. PLoS One. 2015; 2015 Feb 3. PMID: 25647685

Yao Y, Liu R, Shin MS, Trentalange M, Allore H, Nassar A, Kang I, Pober JS, Montgomery RR: CyTOF supports efficient detection of immune cell subsets from small samples. J Immunol Methods. 2014 Dec 15; 2014 Nov 4. PMID: 25450003

Viscoli CM, Brass LM, Carolei A, Conwit R, Ford GA, Furie KL, Gorman M, Guarino PD, Inzucchi SE, Lovejoy AM, Parsons MW, Peduzzi PN, Ringleb PA, Schwartz GG, Spence JD, Tanne D, Young LH, Kernan WN, IRIS Trial investigators: Pioglitazone for secondary prevention after ischemic stroke and transient ischemic attack: rationale and design of the Insulin Resistance Intervention after Stroke Trial. Am Heart J. 2014 Dec; 2014 Jul 28. PMID: 25458644

Fried TR, O'Leary J, Towle V, Goldstein MK, Trentalange M, Martin DK: Health outcomes associated with polypharmacy in community-dwelling older adults: a systematic review. J Am Geriatr Soc. 2014 Dec. PMID: 25516023

O Hartaigh B, Gaksch M, Kienreich K, Grübler MR, Verheyen N, März W, Tomaschitz A, Gill TM, Pilz S: Associations of daytime, nighttime, and 24-hour heart rate with four distinct markers of inflammation in hypertensive patients: the Styrian Hypertension Study. J Clin Hypertens (Greenwich). 2014 Dec; 2014 Sep 30. PMID: 25266946

Goyal G, Pisani MA, Murphy TE, Araujo KL, Puchalski JT: Advanced diagnostic bronchoscopy using conscious sedation and the laryngeal nerve block: tolerability, thoroughness, and diagnostic yield. Lung. 2014 Dec; 2014 Jun 28. PMID: 24972639

Heffelfinger C, Fragoso CA, Moreno MA, Overton JD, Mottinger JP, Zhao H, Tohme J, Dellaporta SL: Flexible and scalable genotyping-by-sequencing strategies for population studies. BMC Genomics. 2014 Nov 18; 2014 Nov 18. PMID: 25406744

Sun N, Zhao H: Putting things in order. Proc Natl Acad Sci U S A. 2014 Nov 18; 2014 Nov 7. PMID: 25380598

Dodson JA, Geda M, Krumholz HM, Lorenze N, Murphy TE, Allore HG, Charpentier P, Tsang SW, Acampora D, Tinetti ME, Gill TM, Chaudhry SI: Design and rationale of the comprehensive evaluation of risk factors in older patients with AMI (SILVER-AMI) study. BMC Health Serv Res. 2014 Nov 5; 2014 Nov 5. PMID: 25370536

Beech RD, Leffert JJ, Lin A, Hong KA, Hansen J, Umlauf S, Mane S, Zhao H, Sinha R: Stress-related alcohol consumption in heavy drinkers correlates with expression of miR-10a, miR-21, and components of the TAR-RNA-binding protein-associated complex. Alcohol Clin Exp Res. 2014 Nov. PMID: 25421511

Zhang H, Wang F, Xu H, Liu Y, Liu J, Zhao H, Gelernter J: Differentially co-expressed genes in postmortem prefrontal cortex of individuals with alcohol use disorders: influence on alcohol metabolism-related pathways. Hum Genet. 2014 Nov; 2014 Jul 30. PMID: 25073604

Walke LM, Rosenthal RA, Trentalange M, Perkal MF, Maiaroto M, Jeffery SM, Marottoli RA: Restructuring care for older adults undergoing surgery: preliminary data from the Co-Management of Older Operative Patients En Route Across Treatment Environments (CO-OPERATE) model of care. J Am Geriatr Soc. 2014 Nov; 2014 Nov 4. PMID: 25369755

Tinetti ME, Han L, McAvay GJ: Risks and benefits of antihypertensive medications in older adults--reply. JAMA Intern Med. 2014 Nov. PMID: 25365161

Chung D, Yang C, Li C, Gelernter J, Zhao H: GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation. PLoS Genet. 2014 Nov; 2014 Nov 13. PMID: 25393678

Hou L, Ma T, Zhao H: Incorporating functional annotation information in prioritizing disease associated SNPs from genome wide association studies. Sci China Life Sci. 2014 Nov; 2014 Oct 17. PMID: 25326070

Bastian LA, Trentalange M, Murphy TE, Brandt C, Bean-Mayberry B, Maisel NC, Wright SM, Gaetano VS, Allore H, Skanderson M, Reyes-Harvey E, Yano EM, Rose D, Haskell S: Association between women veterans' experiences with VA outpatient health care and designation as a women's health provider in primary care clinics. Womens Health Issues. 2014 Nov-Dec; 2014 Oct 28. PMID: 25442706

Juthani-Mehta M, Datunashvili A, Tinetti M: Tests for urinary tract infection in nursing home residents. JAMA. 2014 Oct 22-29. PMID: 25335152

O'Hartaigh B, Pahor M, Buford TW, Dodson JA, Forman DE, Gill TM, LIFE Study Group: Physical activity and resting pulse rate in older adults: findings from a randomized controlled trial. Am Heart J. 2014 Oct; 2014 Jul 30. PMID: 25262271

Graham-Steed TR, Soulos PR, Dearing N, Concato J, Tinetti ME, Gross CP: Development and validation of a prognostic index for fracture risk in older men undergoing prostate cancer treatment. J Geriatr Oncol. 2014 Oct 1; 2014 Sep 18. PMID: 25240918

Malinis MF, Chen S, Allore HG, Quagliarello VJ: Outcomes among older adult liver transplantation recipients in the model of end stage liver disease (MELD) era. Ann Transplant. 2014 Sep 26; 2014 Sep 26. PMID: 25256592

Della-Morte D, Wang L, Beecham A, Blanton SH, Zhao H, Sacco RL, Rundek T, Dong C: Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics. J Neurol Sci. 2014 Sep 15; 2014 Jun 14. PMID: 24954085

Xie P, Kranzler HR, Krystal JH, Farrer LA, Zhao H, Gelernter J: Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence. Addict Biol. 2014 Sep; 2013 Jul 16. PMID: 23855403

Knauert MP, Yaggi HK, Redeker NS, Murphy TE, Araujo KL, Pisani MA: Feasibility study of unattended polysomnography in medical intensive care unit patients. Heart Lung. 2014 Sep-Oct; 2014 Jul 12. PMID: 25023504

Zhang H, Wang F, Kranzler HR, Yang C, Xu H, Wang Z, Zhao H, Gelernter J: Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes. Hum Genet. 2014 Sep; 2014 Jun 3. PMID: 24889829

Case SM, O'Leary J, Kim N, Tinetti ME, Fried TR: Relationship between universal health outcome priorities and willingness to take medication for primary prevention of myocardial infarction. J Am Geriatr Soc. 2014 Sep; 2014 Aug 22. PMID: 25146885

Vaz Fragoso CA, Hsu FC, Brinkley T, Church T, Liu CK, Manini T, Newman AB, Stafford RS, McDermott MM, Gill TM, LIFE Study Group: Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations. J Am Med Dir Assoc. 2014 Sep; 2014 Jun 25. PMID: 24973990

Li B, Chun H, Zhao H: On an Additive Semigraphoid Model for Statistical Networks With Application to Pathway Analysis. J Am Stat Assoc. 2014 Sep. PMID: 26401064

Ó Hartaigh B, Gill TM, Shah I, Hughes AD, Deanfield JE, Kuh D, Hardy R: Association between resting heart rate across the life course and all-cause mortality: longitudinal findings from the Medical Research Council (MRC) National Survey of Health and Development (NSHD). J Epidemiol Community Health. 2014 Sep; 2014 May 21. PMID: 24850484

Zapata HJ, Shaw AC: Aging of the human innate immune system in HIV infection. Curr Opin Immunol. 2014 Aug; 2014 Jul 2. PMID: 24997358

Gill TM: Disentangling the disabling process: insights from the precipitating events project. Gerontologist. 2014 Aug. PMID: 25035454

Lin H, Han L, Peduzzi PN, Murphy TE, Gill TM, Allore HG: A dynamic trajectory class model for intensive longitudinal categorical outcome. Stat Med. 2014 Jul 10; 2014 Feb 11. PMID: 24519416

Ryslik GA, Cheng Y, Cheung KH, Bjornson RD, Zelterman D, Modis Y, Zhao H: A spatial simulation approach to account for protein structure when identifying non-random somatic mutations. BMC Bioinformatics. 2014 Jul 3; 2014 Jul 3. PMID: 24990767

Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H, Farrer LA: Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry. 2014 Jul 1; 2013 Oct 19. PMID: 24143882

Amjad H, Towle V, Fried T: Association of experience with illness and end-of-life care with advance care planning in older adults. J Am Geriatr Soc. 2014 Jul; 2014 Jun 16. PMID: 24934237

Buurman BM, Trentalange M, Nicholson NR, McGloin JM, Gahbauer EA, Allore HG, Gill TM: Residential relocations among older people over the course of more than 10 years. J Am Med Dir Assoc. 2014 Jul; 2014 May 1. PMID: 24794829

Thomas JM, O'Leary JR, Fried TR: A comparison of the willingness of resident and attending physicians to comply with the requests of patients at the end of life. J Gen Intern Med. 2014 Jul; 2014 Mar 20. PMID: 24647724

Lipska KJ, Ross JS, Wang Y, Inzucchi SE, Minges K, Karter AJ, Huang ES, Desai MM, Gill TM, Krumholz HM: National trends in US hospital admissions for hyperglycemia and hypoglycemia among Medicare beneficiaries, 1999 to 2011. JAMA Intern Med. 2014 Jul. PMID: 24838229

Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD, LIFE study investigators: Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014 Jun 18. PMID: 24866862

Zhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Lee CG, Elias JA, Herzog EL: Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis. Sci Transl Med. 2014 Jun 11. PMID: 24920662

Chung LM, Colangelo CM, Zhao H: Data Pre-Processing for Label-Free Multiple Reaction Monitoring (MRM) Experiments. Biology (Basel). 2014 Jun 5; 2014 Jun 5. PMID: 24905083

Vaz Fragoso CA, Miller ME, Fielding RA, King AC, Kritchevsky SB, McDermott MM, Myers V, Newman AB, Pahor M, Gill TM, Lifestyle Interventions and Independence in Elder Study Group: Sleep-wake disturbances in sedentary community-dwelling elderly adults with functional limitations. J Am Geriatr Soc. 2014 Jun; 2014 Jun 2. PMID: 24889836

Kookoolis AS, Puchalski JT, Murphy TE, Araujo KL, Pisani MA: Mortality of Hospitalized Patients with Pleural Effusions. J Pulm Respir Med. 2014 Jun. PMID: 25977841

Nish SA, Schenten D, Wunderlich FT, Pope SD, Gao Y, Hoshi N, Yu S, Yan X, Lee HK, Pasman L, Brodsky I, Yordy B, Zhao H, Brüning J, Medzhitov R: T cell-intrinsic role of IL-6 signaling in primary and memory responses. Elife. 2014 May 19; 2014 May 19. PMID: 24842874

Hou L, Chen M, Zhang CK, Cho J, Zhao H: Guilt by rewiring: gene prioritization through network rewiring in genome wide association studies. Hum Mol Genet. 2014 May 15; 2013 Dec 30. PMID: 24381306

Lee N, Shin MS, Kang KS, Yoo SA, Mohanty S, Montgomery RR, Shaw AC, Kang I: Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling. Clin Immunol. 2014 May-Jun; 2014 Mar 19. PMID: 24657713

Zhu R, Zhao H, Ma S: Identifying gene-environment and gene-gene interactions using a progressive penalization approach. Genet Epidemiol. 2014 May; 2014 Apr 10. PMID: 24723356

Li C, Yang C, Gelernter J, Zhao H: Improving genetic risk prediction by leveraging pleiotropy. Hum Genet. 2014 May; 2013 Dec 13. PMID: 24337655

Yang C, Li C, Kranzler HR, Farrer LA, Zhao H, Gelernter J: Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. Hum Genet. 2014 May; 2013 Dec 3. PMID: 24297757

Mannam P, Shinn AS, Srivastava A, Neamu RF, Walker WE, Bohanon M, Merkel J, Kang MJ, Dela Cruz CS, Ahasic AM, Pisani MA, Trentalange M, West AP, Shadel GS, Elias JA, Lee PJ: MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2014 Apr 1; 2014 Jan 31. PMID: 24487387

Vaz Fragoso CA, Beavers DP, Hankinson JL, Flynn G, Berra K, Kritchevsky SB, Liu CK, McDermott MM, Manini TM, Rejeski WJ, Gill TM, Lifestyle Interventions Independence for Elders Study Investigators: Respiratory impairment and dyspnea and their associations with physical inactivity and mobility in sedentary community-dwelling older persons. J Am Geriatr Soc. 2014 Apr; 2014 Mar 17. PMID: 24635756

Tinetti ME, Han L, Lee DS, McAvay GJ, Peduzzi P, Gross CP, Zhou B, Lin H: Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults. JAMA Intern Med. 2014 Apr. PMID: 24567036

Ryslik GA, Cheng Y, Cheung KH, Modis Y, Zhao H: A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations. BMC Bioinformatics. 2014 Mar 26; 2014 Mar 26. PMID: 24669769

Sauler M, Leng L, Trentalange M, Haslip M, Shan P, Piecychna M, Zhang Y, Andrews N, Mannam P, Allore H, Fried T, Bucala R, Lee PJ: Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15; 2014 Jan 17. PMID: 24441872

de Rekeneire N, Leo-Summers L, Han L, Gill TM: Epidemiology of restricting fatigue in older adults: the precipitating events project. J Am Geriatr Soc. 2014 Mar; 2014 Feb 11. PMID: 24512073

Tinetti ME: The gap between clinical trials and the real world: extrapolating treatment effects from younger to older adults. JAMA Intern Med. 2014 Mar. PMID: 24424303

Lee DS, Markwardt S, McAvay GJ, Gross CP, Goeres LM, Han L, Peduzzi P, Lin H, Dodson JA, Tinetti ME: Effect of β-blockers on cardiac and pulmonary events and death in older adults with cardiovascular disease and chronic obstructive pulmonary disease. Med Care. 2014 Mar. PMID: 24561758

Tinetti ME, Basu J: Research on multiple chronic conditions: where we are and where we need to go. Med Care. 2014 Mar. PMID: 24561755

Erekson EA, Martin DK, Brousseau EC, Yip SO, Fried TR: Over-the-counter treatments and perineal hygiene in postmenopausal women. Menopause. 2014 Mar. PMID: 23880795

Li D, Sulovari A, Cheng C, Zhao H, Kranzler HR, Gelernter J: Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder. Neuropsychopharmacology. 2014 Mar; 2013 Oct 18. PMID: 24136292

Reuben DB, Tinetti ME: The hospital-dependent patient. N Engl J Med. 2014 Feb 20. PMID: 24552316

Qian F, Guo X, Wang X, Yuan X, Chen S, Malawista SE, Bockenstedt LK, Allore HG, Montgomery RR: Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging. Aging (Albany NY). 2014 Feb. PMID: 24595889

Brummel NE, Jackson JC, Pandharipande PP, Thompson JL, Shintani AK, Dittus RS, Gill TM, Bernard GR, Ely EW, Girard TD: Delirium in the ICU and subsequent long-term disability among survivors of mechanical ventilation. Crit Care Med. 2014 Feb. PMID: 24158172

Brown JE, Evans BR, Zheng W, Obas V, Barrera-Martinez L, Egizi A, Zhao H, Caccone A, Powell JR: Human impacts have shaped historical and recent evolution in Aedes aegypti, the dengue and yellow fever mosquito. Evolution. 2014 Feb; 2013 Oct 23. PMID: 24111703

Assis DN, Leng L, Du X, Zhang CK, Grieb G, Merk M, Garcia AB, McCrann C, Chapiro J, Meinhardt A, Mizue Y, Nikolic-Paterson DJ, Bernhagen J, Kaplan MM, Zhao H, Boyer JL, Bucala R: The role of macrophage migration inhibitory factor in autoimmune liver disease. Hepatology. 2014 Feb; 2013 Dec 20. PMID: 23913513

Juthani-Mehta M, Guo X, Shaw AC, Towle V, Ning Y, Wang X, Allore HG, Fikrig E, Montgomery RR: Innate Immune Responses in the Neutrophils of Community Dwelling and Nursing Home Elders. J Aging Sci. 2014 Jan 27. PMID: 25750929

Schenten D, Nish SA, Yu S, Yan X, Lee HK, Brodsky I, Pasman L, Yordy B, Wunderlich FT, Brüning JC, Zhao H, Medzhitov R: Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells. Immunity. 2014 Jan 16. PMID: 24439266

Xu F, Li L, Schulz VP, Gallagher PG, Xiang B, Zhao H, Li P: Cytogenomic mapping and bioinformatic mining reveal interacting brain expressed genes for intellectual disability. Mol Cytogenet. 2014 Jan 10; 2014 Jan 10. PMID: 24410907

Wang L, Rundek T, Beecham A, Hudson B, Blanton SH, Zhao H, Sacco RL, Dong C: Genome-wide interaction study identifies RCBTB1 as a modifier for smoking effect on carotid intima-media thickness. Arterioscler Thromb Vasc Biol. 2014 Jan; 2013 Nov 7. PMID: 24202307

Yang C, Li C, Chen M, Chen X, Hou L, Zhao H: A penalized linear mixed model for genomic prediction using pedigree structures. BMC Proc. 2014; 2014 Jun 17. PMID: 25519399

Li C, Yang C, Chen M, Chen X, Hou L, Zhao H: Adjustment of familial relatedness in association test for rare variants. BMC Proc. 2014; 2014 Jun 17. PMID: 25519384

Chen M, Yang C, Li C, Hou L, Chen X, Zhao H: Admixture mapping analysis in the context of GWAS with GAW18 data. BMC Proc. 2014; 2014 Jun 17. PMID: 25519317

Pang H, Zhao H: Stratified pathway analysis to identify gene sets associated with oral contraceptive use and breast cancer. Cancer Inform. 2014; 2014 Dec 9. PMID: 25574128

Kim M, Chen X, Chin LJ, Paranjape T, Speed WC, Kidd KK, Zhao H, Weidhaas JB, Slack FJ: Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases. Cell Cycle. 2014; 2014 Feb 3. PMID: 24552817

Sink KM, Espeland MA, Rushing J, Castro CM, Church TS, Cohen R, Gill TM, Henkin L, Jennings JM, Kerwin DR, Manini TM, Myers V, Pahor M, Reid KF, Woolard N, Rapp SR, Williamson JD, LIFE Investigators: The LIFE Cognition Study: design and baseline characteristics. Clin Interv Aging. 2014; 2014 Aug 27. PMID: 25210447

Makris UE, Fraenkel L, Han L, Leo-Summers L, Gill TM: Risk factors for restricting back pain in older persons. J Am Med Dir Assoc. 2014 Jan; 2013 Nov 15. PMID: 24239445

Murphy TE, Baker DI, Leo-Summers LS, Tinetti ME: Trends in Fall-Related Traumatic Brain Injury among Older Persons in Connecticut from 2000-2007. J Gerontol Geriatr Res. 2014. PMID: 25558438

Gupta AR, Pirruccello M, Cheng F, Kang HJ, Fernandez TV, Baskin JM, Choi M, Liu L, Ercan-Sencicek AG, Murdoch JD, Klei L, Neale BM, Franjic D, Daly MJ, Lifton RP, De Camilli P, Zhao H, Sestan N, State MW: Rare deleterious mutations of the gene EFR3A in autism spectrum disorders. Mol Autism. 2014; 2014 Apr 29. PMID: 24860643

Fried TR, O'Leary J, Towle V, Goldstein MK, Trentelange M, Martin DK: The effects of comorbidity on the benefits and harms of treatment for chronic disease: a systematic review. PLoS One. 2014; 2014 Nov 17. PMID: 25402463

Tinetti ME, Han L, McAvay GJ, Lee DS, Peduzzi P, Dodson JA, Gross CP, Zhou B, Lin H: Anti-hypertensive medications and cardiovascular events in older adults with multiple chronic conditions. PLoS One. 2014; 2014 Mar 10. PMID: 24614535

Lorgunpai SJ, Grammas M, Lee DS, McAvay G, Charpentier P, Tinetti ME: Potential therapeutic competition in community-living older adults in the U.S.: use of medications that may adversely affect a coexisting condition. PLoS One. 2014; 2014 Feb 25. PMID: 24586786

Panda A, Chen S, Shaw AC, Allore HG: Statistical approaches for analyzing immunologic data of repeated observations: a practical guide. J Immunol Methods. 2013 Dec 15; 2013 Sep 18. PMID: 24055129

Bikdeli B, Wang Y, Kim N, Desai MM, Quagliarello V, Krumholz HM: Trends in hospitalization rates and outcomes of endocarditis among Medicare beneficiaries. J Am Coll Cardiol. 2013 Dec 10; 2013 Aug 28. PMID: 23994421

Hou L, Zhao H: A review of post-GWAS prioritization approaches. Front Genet. 2013 Dec 9; 2013 Dec 9. PMID: 24367376

Han S, Yang BZ, Kranzler HR, Liu X, Zhao H, Farrer LA, Boerwinkle E, Potash JB, Gelernter J: Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. Am J Hum Genet. 2013 Dec 5; 2013 Nov 21. PMID: 24268660

Shaw AC, Goldstein DR, Montgomery RR: Age-dependent dysregulation of innate immunity. Nat Rev Immunol. 2013 Dec; 2013 Oct 25. PMID: 24157572

Fried LF, Emanuele N, Zhang JH, Brophy M, Conner TA, Duckworth W, Leehey DJ, McCullough PA, O'Connor T, Palevsky PM, Reilly RF, Seliger SL, Warren SR, Watnick S, Peduzzi P, Guarino P, VA NEPHRON-D Investigators: Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med. 2013 Nov 14; 2013 Nov 9. PMID: 24206457

Xie P, Kranzler HR, Yang C, Zhao H, Farrer LA, Gelernter J: Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry. 2013 Nov 1; 2013 May 28. PMID: 23726511

Zhang S, Zhao H: Normalized modularity optimization method for community identification with degree adjustment. Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Nov; 2013 Nov 4. PMID: 24329313

Gill TM, Murphy TE, Gahbauer EA, Allore HG: The course of disability before and after a serious fall injury. JAMA Intern Med. 2013 Oct 28. PMID: 23958741

Gao Y, Nish SA, Jiang R, Hou L, Licona-Limón P, Weinstein JS, Zhao H, Medzhitov R: Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity. 2013 Oct 17; 2013 Sep 26. PMID: 24076050

Murphy TE, Baker DI, Leo-Summers LS, Allore HG, Tinetti ME: Association between treatment or usual care region and hospitalization for fall-related traumatic brain injury in the Connecticut Collaboration for Fall Prevention. J Am Geriatr Soc. 2013 Oct; 2013 Sep 19. PMID: 24083593

Vaz Fragoso CA, Van Ness PH, Araujo KL, Iannone LP, Marottoli RA: Sleep disturbances and driving practices of older drivers. J Am Geriatr Soc. 2013 Oct; 2013 Sep 3. PMID: 24001143

Fodeh SJ, Lazenby M, Bai M, Ercolano E, Murphy T, McCorkle R: Functional impairments as symptoms in the symptom cluster analysis of patients newly diagnosed with advanced cancer. J Pain Symptom Manage. 2013 Oct; 2013 Feb 4. PMID: 23380336

Chaudhry SI, Murphy TE, Gahbauer E, Sussman LS, Allore HG, Gill TM: Restricting symptoms in the last year of life: a prospective cohort study. JAMA Intern Med. 2013 Sep 9. PMID: 23836056

Pisani MA, Bramley K, Vest MT, Akgün KM, Araujo KL, Murphy TE: Patterns of opiate, benzodiazepine, and antipsychotic drug dosing in older patients in a medical intensive care unit. Am J Crit Care. 2013 Sep. PMID: 23996429

Chen X, Slack FJ, Zhao H: Joint analysis of expression profiles from multiple cancers improves the identification of microRNA-gene interactions. Bioinformatics. 2013 Sep 1; 2013 Jun 14. PMID: 23772050

Erekson EA, Yip SO, Wedderburn TS, Martin DK, Li FY, Choi JN, Kenton KS, Fried TR: The Vulvovaginal Symptoms Questionnaire: a questionnaire for measuring vulvovaginal symptoms in postmenopausal women. Menopause. 2013 Sep. PMID: 23481118

Dziura JD, Post LA, Zhao Q, Fu Z, Peduzzi P: Strategies for dealing with missing data in clinical trials: from design to analysis. Yale J Biol Med. 2013 Sep; 2013 Sep 20. PMID: 24058309

Gill TM, Murphy TE, Gahbauer EA, Allore HG: Association of injurious falls with disability outcomes and nursing home admissions in community-living older persons. Am J Epidemiol. 2013 Aug 1; 2013 Apr 1. PMID: 23548756

Puchalski JT, Argento AC, Murphy TE, Araujo KL, Pisani MA: The safety of thoracentesis in patients with uncorrected bleeding risk. Ann Am Thorac Soc. 2013 Aug. PMID: 23952852

Case SM, Towle VR, Fried TR: Considering the balance: development of a scale to assess patient views on trade-offs in competing health outcomes. J Am Geriatr Soc. 2013 Aug; 2013 Jul 19. PMID: 23869795

Gancayco J, Soulos PR, Khiani V, Cramer LD, Ross JS, Genao I, Tinetti M, Gross CP: Age-based and sex-based disparities in screening colonoscopy use among medicare beneficiaries. J Clin Gastroenterol. 2013 Aug. PMID: 23619827

Horwitz LI, Jenq GY, Brewster UC, Chen C, Kanade S, Van Ness PH, Araujo KL, Ziaeian B, Moriarty JP, Fogerty RL, Krumholz HM: Comprehensive quality of discharge summaries at an academic medical center. J Hosp Med. 2013 Aug; 2013 Mar 22. PMID: 23526813

Qian F, Chung L, Zheng W, Bruno V, Alexander RP, Wang Z, Wang X, Kurscheid S, Zhao H, Fikrig E, Gerstein M, Snyder M, Montgomery RR: Identification of genes critical for resistance to infection by West Nile virus using RNA-Seq analysis. Viruses. 2013 Jul 8; 2013 Jul 8. PMID: 23881275

Saxe JP, Chen M, Zhao H, Lin H: Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J. 2013 Jul 3; 2013 May 28. PMID: 23714778

Zhang CK, Hewett J, Hemming J, Grant T, Zhao H, Abraham C, Oikonomou I, Kanakia M, Cho JH, Proctor DD: The influence of depression on quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2013 Jul. PMID: 23669400

Juthani-Mehta M, De Rekeneire N, Allore H, Chen S, O'Leary JR, Bauer DC, Harris TB, Newman AB, Yende S, Weyant RJ, Kritchevsky S, Quagliarello V, Health ABC Study: Modifiable risk factors for pneumonia requiring hospitalization of community-dwelling older adults: the Health, Aging, and Body Composition Study. J Am Geriatr Soc. 2013 Jul; 2013 Jun 17. PMID: 23772872

Botoseneanu A, Allore HG, Gahbauer EA, Gill TM: Long-term trajectories of lower extremity function in older adults: estimating gender differences while accounting for potential mortality bias. J Gerontol A Biol Sci Med Sci. 2013 Jul; 2012 Nov 16. PMID: 23160367

Ma H, Zhao H: Drug target inference through pathway analysis of genomics data. Adv Drug Deliv Rev. 2013 Jun 30; 2013 Jan 28. PMID: 23369829

Tinetti M: ACP Journal Club. Review: acute geriatric unit care reduces falls, delirium, and functional decline. Ann Intern Med. 2013 Jun 18. PMID: 23778923

Zhang H, Wang F, Kranzler HR, Zhao H, Gelernter J: Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls. PLoS One. 2013; 2013 Jun 14. PMID: 23799031

Ryslik GA, Cheng Y, Cheung KH, Modis Y, Zhao H: Utilizing protein structure to identify non-random somatic mutations. BMC Bioinformatics. 2013 Jun 13; 2013 Jun 13. PMID: 23758891

Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, Romano-Adesman A, Bjornson RD, Breitbart RE, Brown KK, Carriero NJ, Cheung YH, Deanfield J, DePalma S, Fakhro KA, Glessner J, Hakonarson H, Italia MJ, Kaltman JR, Kaski J, Kim R, Kline JK, Lee T, Leipzig J, Lopez A, Mane SM, Mitchell LE, Newburger JW, Parfenov M, Pe'er I, Porter G, Roberts AE, Sachidanandam R, Sanders SJ, Seiden HS, State MW, Subramanian S, Tikhonova IR, Wang W, Warburton D, White PS, Williams IA, Zhao H, Seidman JG, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Seidman CE, Lifton RP: De novo mutations in histone-modifying genes in congenital heart disease. Nature. 2013 Jun 13; 2013 May 12. PMID: 23665959

Tinetti ME, Basch E: Patients' responsibility to participate in decision making and research. JAMA. 2013 Jun 12. PMID: 23700165

Walke LM, Tinetti ME: ACE, MACE, and GRACE: time to put the pieces together: comment on "effects of an acute care for elders unit on costs and 30-day readmissions". JAMA Intern Med. 2013 Jun 10. PMID: 23608885

Akgün KM, Tate JP, Pisani M, Fried T, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K: Medical ICU admission diagnoses and outcomes in human immunodeficiency virus-infected and virus-uninfected veterans in the combination antiretroviral era. Crit Care Med. 2013 Jun. PMID: 23507717

Ferguson J, Wheeler W, Fu Y, Prokunina-Olsson L, Zhao H, Sampson J: Statistical tests for detecting associations with groups of genetic variants: generalization, evaluation, and implementation. Eur J Hum Genet. 2013 Jun; 2012 Oct 24. PMID: 23092956

Murphy TE, Baker DI, Leo-Summers LS, Bianco L, Gottschalk M, Acampora D, King MB: Integration of fall prevention into state policy in Connecticut. Gerontologist. 2013 Jun; 2012 Oct 4. PMID: 23042690

Thomas JM, Cooney LM Jr, Fried TR: Systematic review: Health-related characteristics of elderly hospitalized adults and nursing home residents associated with short-term mortality. J Am Geriatr Soc. 2013 Jun; 2013 May 20. PMID: 23692412

Fodeh SJ, Brandt C, Luong TB, Haddad A, Schultz M, Murphy T, Krauthammer M: Complementary ensemble clustering of biomedical data. J Biomed Inform. 2013 Jun; 2013 Feb 27. PMID: 23454721

Kang KS, Lee N, Shin MS, Kim SD, Yu Y, Mohanty S, Belshe RB, Montgomery RR, Shaw AC, Kang I: An altered relationship of influenza vaccine-specific IgG responses with T cell immunity occurs with aging in humans. Clin Immunol. 2013 May; 2013 Mar 15. PMID: 23578549

Horwitz LI, Dombroski J, Murphy TE, Farnan JM, Johnson JK, Arora VM: Validation of a handoff assessment tool: the Handoff CEX. J Clin Nurs. 2013 May; 2012 Jun 7. PMID: 22671983

Yang C, Wang L, Zhang S, Zhao H: Accounting for non-genetic factors by low-rank representation and sparse regression for eQTL mapping. Bioinformatics. 2013 Apr 15; 2013 Feb 17. PMID: 23419377

Gill TM, Gahbauer EA, Lin H, Han L, Allore HG: Comparisons between older men and women in the trajectory and burden of disability over the course of nearly 14 years. J Am Med Dir Assoc. 2013 Apr; 2013 Jan 4. PMID: 23294968

Horwitz LI, Rand D, Staisiunas P, Van Ness PH, Araujo KL, Banerjee SS, Farnan JM, Arora VM: Development of a handoff evaluation tool for shift-to-shift physician handoffs: the Handoff CEX. J Hosp Med. 2013 Apr. PMID: 23559502

Pietrzak RH, Van Ness PH, Fried TR, Galea S, Norris FH: Trajectories of posttraumatic stress symptomatology in older persons affected by a large-magnitude disaster. J Psychiatr Res. 2013 Apr; 2013 Jan 4. PMID: 23290559

Case SM, Fried TR, O'Leary J: How to ask: older adults' preferred tools in health outcome prioritization. Patient Educ Couns. 2013 Apr; 2012 Dec 4. PMID: 23218242

Chung LM, Ferguson JP, Zheng W, Qian F, Bruno V, Montgomery RR, Zhao H: Differential expression analysis for paired RNA-Seq data. BMC Bioinformatics. 2013 Mar 27; 2013 Mar 27. PMID: 23530607

Zheng W, Zhao H: Studying the evolution of transcription factor binding events using multi-species ChIP-Seq data. Stat Appl Genet Mol Biol. 2013 Mar 26; 2013 Mar 26. PMID: 23446869

Falzer PR, Leventhal HL, Peters E, Fried TR, Kerns R, Michalski M, Fraenkel L: The practitioner proposes a treatment change and the patient declines: what to do next? Pain Pract. 2013 Mar; 2012 Jul 2. PMID: 23462141

Chaudhry SI, McAvay G, Chen S, Whitson H, Newman AB, Krumholz HM, Gill TM: Risk factors for hospital admission among older persons with newly diagnosed heart failure: findings from the Cardiovascular Health Study. J Am Coll Cardiol. 2013 Feb 12. PMID: 23391194

Han L, Allore H, Murphy T, Gill T, Peduzzi P, Lin H: Dynamics of functional aging based on latent-class trajectories of activities of daily living. Ann Epidemiol. 2013 Feb. PMID: 23305692

Qian F, Bolen CR, Jing C, Wang X, Zheng W, Zhao H, Fikrig E, Bruce RD, Kleinstein SH, Montgomery RR: Impaired toll-like receptor 3-mediated immune responses from macrophages of patients chronically infected with hepatitis C virus. Clin Vaccine Immunol. 2013 Feb; 2012 Dec 5. PMID: 23220997

Puchalski JT, Argento AC, Murphy TE, Araujo KL, Oliva IB, Rubinowitz AN, Pisani MA: Etiologies of bilateral pleural effusions. Respir Med. 2013 Feb; 2012 Dec 7. PMID: 23219348

Reilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA, Herzog EL: Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis. Am J Respir Crit Care Med. 2013 Jan 15; 2012 Dec 6. PMID: 23220917

Zhang H, Herman AI, Kranzler HR, Anton RF, Zhao H, Zheng W, Gelernter J: Array-based profiling of DNA methylation changes associated with alcohol dependence. Alcohol Clin Exp Res. 2013 Jan; 2012 Aug 24. PMID: 22924764

Vaz Fragoso CA, Gill TM, McAvay G, Quanjer PH, Van Ness PH, Concato J: Respiratory impairment in older persons: when less means more. Am J Med. 2013 Jan; 2012 Nov 20. PMID: 23177541

Lin H, Allore HG, McAvay G, Tinetti ME, Gill TM, Gross CP, Murphy TE: A method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome. Am J Public Health. 2013 Jan; 2012 Apr 19. PMID: 22515873

Bruvik FK, Allore HG, Ranhoff AH, Engedal K: The effect of psychosocial support intervention on depression in patients with dementia and their family caregivers: an assessor-blinded randomized controlled trial. Dement Geriatr Cogn Dis Extra. 2013; 2013 Oct 26. PMID: 24348500

Ning Y, McAvay G, Chaudhry SI, Arnold AM, Allore HG: Results differ by applying distinctive multiple imputation approaches on the longitudinal cardiovascular health study data. Exp Aging Res. 2013. PMID: 23316735

Chun H, Chen M, Li B, Zhao H: Joint conditional Gaussian graphical models with multiple sources of genomic data. Front Genet. 2013; 2013 Dec 17. PMID: 24381584

Ferguson JP, Cho JH, Yang C, Zhao H: Empirical Bayes correction for the Winner's Curse in genetic association studies. Genet Epidemiol. 2013 Jan; 2012 Sep 25. PMID: 23012258

Allore HG, Ning Y, Brandt CA, Goulet JL: Accounting for the Hierarchical Structure in Veterans Health Administration Data: Differences in Healthcare Utilization between Men and Women Veterans. Int J Stat Med Res. 2013. PMID: 24910720

Akgün KM, Gordon K, Pisani M, Fried T, McGinnis KA, Tate JP, Butt AA, Gibert CL, Huang L, Rodriguez-Barradas MC, Rimland D, Justice AC, Crothers K: Risk factors for hospitalization and medical intensive care unit (MICU) admission among HIV-infected Veterans. J Acquir Immune Defic Syndr. 2013 Jan 1. PMID: 23111572

Chen M, Gunel M, Zhao H: SomatiCA: identifying, characterizing and quantifying somatic copy number aberrations from cancer genome sequencing data. PLoS One. 2013; 2013 Nov 12. PMID: 24265680

Dharmarajan K, Strait KM, Lagu T, Lindenauer PK, Tinetti ME, Lynn J, Li SX, Krumholz HM: Acute decompensated heart failure is routinely treated as a cardiopulmonary syndrome. PLoS One. 2013; 2013 Oct 21. PMID: 24250751

Cone DC, Ahern J, Lee CH, Baker D, Murphy T, Bogucki S: A descriptive study of the "lift-assist" call. Prehosp Emerg Care. 2013 Jan-Mar; 2012 Sep 12. PMID: 22971148

Levy BR, Slade MD, Murphy TE, Gill TM: Association between positive age stereotypes and recovery from disability in older persons. JAMA. 2012 Nov 21. PMID: 23168819

Van Ness PH, Peduzzi PN, Quagliarello VJ: Efficacy and effectiveness as aspects of cluster randomized trials with nursing home residents: methodological insights from a pneumonia prevention trial. Contemp Clin Trials. 2012 Nov; 2012 Aug 11. PMID: 22917599

Ziaeian B, Araujo KL, Van Ness PH, Horwitz LI: Medication reconciliation accuracy and patient understanding of intended medication changes on hospital discharge. J Gen Intern Med. 2012 Nov; 2012 Jul 14. PMID: 22798200

Ma H, Zhao H: FacPad: Bayesian sparse factor modeling for the inference of pathways responsive to drug treatment. Bioinformatics. 2012 Oct 15; 2012 Aug 24. PMID: 22923307

Ge X, Ren Y, Bartulos O, Lee MY, Yue Z, Kim KY, Li W, Amos PJ, Bozkulak EC, Iyer A, Zheng W, Zhao H, Martin KA, Kotton DN, Tellides G, Park IH, Yue L, Qyang Y: Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells. Circulation. 2012 Oct 2; 2012 Aug 22. PMID: 22914687

Pietrzak RH, Van Ness PH, Fried TR, Galea S, Norris F: Diagnostic utility and factor structure of the PTSD Checklist in older adults. Int Psychogeriatr. 2012 Oct; 2012 May 30. PMID: 22647669

Chang SS, Chen S, McAvay GJ, Tinetti ME: Effect of coexisting chronic obstructive pulmonary disease and cognitive impairment on health outcomes in older adults. J Am Geriatr Soc. 2012 Oct; 2012 Oct 4. PMID: 23035917

Fried TR, Vaz Fragoso CA, Rabow MW: Caring for the older person with chronic obstructive pulmonary disease. JAMA. 2012 Sep 26. PMID: 23011715

Lowthert L, Leffert J, Lin A, Umlauf S, Maloney K, Muralidharan A, Lorberg B, Mane S, Zhao H, Sinha R, Bhagwagar Z, Beech R: Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation. Biol Mood Anxiety Disord. 2012 Sep 12; 2012 Sep 12. PMID: 22967286

Beech RD, Qu J, Leffert JJ, Lin A, Hong KA, Hansen J, Umlauf S, Mane S, Zhao H, Sinha R: Altered expression of cytokine signaling pathway genes in peripheral blood cells of alcohol dependent subjects: preliminary findings. Alcohol Clin Exp Res. 2012 Sep; 2012 Apr 4. PMID: 22471388

Erekson EA, Yip SO, Martin DK, Ciarleglio MM, Connell KA, Fried TR: Major postoperative complications after benign gynecologic surgery: a clinical prediction tool. Female Pelvic Med Reconstr Surg. 2012 Sep-Oct. PMID: 22983270

Chen X, Listman JB, Slack FJ, Gelernter J, Zhao H: Biases and errors on allele frequency estimation and disease association tests of next-generation sequencing of pooled samples. Genet Epidemiol. 2012 Sep; 2012 Jun 6. PMID: 22674656

Li D, Zhao H, Gelernter J: Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases. Hum Genet. 2012 Aug; 2012 Apr 5. PMID: 22476623

Fraenkel L, Street RL Jr, Towle V, O'Leary JR, Iannone L, Van Ness PH, Fried TR: A pilot randomized controlled trial of a decision support tool to improve the quality of communication and decision-making in individuals with atrial fibrillation. J Am Geriatr Soc. 2012 Aug; 2012 Aug 2. PMID: 22861171

Tinetti ME, Charpentier P, Gottschalk M, Baker DI: Effect of a restorative model of posthospital home care on hospital readmissions. J Am Geriatr Soc. 2012 Aug; 2012 Aug 2. PMID: 22860756

Tinetti ME, McAvay GJ, Murphy TE, Gross CP, Lin H, Allore HG: Contribution of individual diseases to death in older adults with multiple diseases. J Am Geriatr Soc. 2012 Aug; 2012 Jun 26. PMID: 22734792

Ma H, Zhao H: iFad: an integrative factor analysis model for drug-pathway association inference. Bioinformatics. 2012 Jul 15; 2012 May 10. PMID: 22581178

Fraenkel L, Peters E, Charpentier P, Olsen B, Errante L, Schoen RT, Reyna V: Decision tool to improve the quality of care in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2012 Jul. PMID: 22392766

Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Gill TM: Respiratory impairment and COPD hospitalisation in older persons: a competing risk analysis. Eur Respir J. 2012 Jul; 2012 Jan 20. PMID: 22267770

Lee DS, de Rekeneire N, Hanlon JT, Gill TM, Bauer DC, Meibohm B, Harris TB, Jeffery SM: Cognitive Impairment and Medication Complexity in Community-Living Older Adults: The Health, Aging and Body Composition Study. J Pharm Technol. 2012 Jul 1. PMID: 24660166

Tinetti ME, Fried TR, Boyd CM: Designing health care for the most common chronic condition--multimorbidity. JAMA. 2012 Jun 20. PMID: 22797447

Erekson EA, Ratner ES, Walke LM, Fried TR: Gynecologic surgery in the geriatric patient. Obstet Gynecol. 2012 Jun. PMID: 22617593

Jenq G, Tinetti ME: The journey across the health care (dis)continuum for vulnerable patients: policies, pitfalls, and possibilities. JAMA. 2012 May 23. PMID: 22618921

Dodson JA, Arnold SV, Reid KJ, Gill TM, Rich MW, Masoudi FA, Spertus JA, Krumholz HM, Alexander KP: Physical function and independence 1 year after myocardial infarction: observations from the Translational Research Investigating Underlying disparities in recovery from acute Myocardial infarction: Patients' Health status registry. Am Heart J. 2012 May. PMID: 22607856

Nunez-Smith M, Ciarleglio MM, Sandoval-Schaefer T, Elumn J, Castillo-Page L, Peduzzi P, Bradley EH: Institutional variation in the promotion of racial/ethnic minority faculty at US medical schools. Am J Public Health. 2012 May; 2012 Mar 15. PMID: 22420820

Li D, Zhao H, Gelernter J: Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians. Hum Genet. 2012 May; 2011 Nov 20. PMID: 22102315

Fraenkel L, Falzer P, Fried T, Kohler M, Peters E, Kerns R, Leventhal H: Measuring pain impact versus pain severity using a numeric rating scale. J Gen Intern Med. 2012 May; 2011 Nov 12. PMID: 22081365

Li D, Zhao H, Kranzler HR, Oslin D, Anton RF, Farrer LA, Gelernter J: Association of COL25A1 with comorbid antisocial personality disorder and substance dependence. Biol Psychiatry. 2012 Apr 15; 2012 Jan 31. PMID: 22297151

Zhang CK, Stein PB, Liu J, Wang Z, Yang R, Cho JH, Gregersen PK, Aerts JM, Zhao H, Pastores GM, Mistry PK: Genome-wide association study of N370S homozygous Gaucher disease reveals the candidacy of CLN8 gene as a genetic modifier contributing to extreme phenotypic variation. Am J Hematol. 2012 Apr; 2012 Mar 3. PMID: 22388998

Morino K, Petersen KF, Sono S, Choi CS, Samuel VT, Lin A, Gallo A, Zhao H, Kashiwagi A, Goldberg IJ, Wang H, Eckel RH, Maegawa H, Shulman GI: Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes. Diabetes. 2012 Apr; 2012 Feb 24. PMID: 22368174

Tinetti ME: The retreat from advanced care planning. JAMA. 2012 Mar 7. PMID: 22396510

Chen D, Zheng W, Lin A, Uyhazi K, Zhao H, Lin H: Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol. 2012 Mar 6; 2012 Feb 16. PMID: 22342750

Santoro N, Zhang CK, Zhao H, Pakstis AJ, Kim G, Kursawe R, Dykas DJ, Bale AE, Giannini C, Pierpont B, Shaw MM, Groop L, Caprio S: Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents. Hepatology. 2012 Mar; 2011 Dec 18. PMID: 22105854

Volkova M, Zhang Y, Shaw AC, Lee PJ: The role of Toll-like receptors in age-associated lung diseases. J Gerontol A Biol Sci Med Sci. 2012 Mar; 2012 Mar 5. PMID: 22396470

Vaz Fragoso CA, Gill TM: Respiratory impairment and the aging lung: a novel paradigm for assessing pulmonary function. J Gerontol A Biol Sci Med Sci. 2012 Mar; 2011 Dec 1. PMID: 22138206

Carling T, Carty SE, Ciarleglio MM, Cooper DS, Doherty GM, Kim LT, Kloos RT, Mazzaferri EL Sr, Peduzzi PN, Roman SA, Sippel RS, Sosa JA, Stack BC Jr, Steward DL, Tufano RP, Tuttle RM, Udelsman R, American Thyroid Association Surgical Affairs Committee: American Thyroid Association design and feasibility of a prospective randomized controlled trial of prophylactic central lymph node dissection for papillary thyroid carcinoma. Thyroid. 2012 Mar; 2012 Feb 7. PMID: 22313454

Ferguson JP, Cho JH, Zhao H: A new approach for the joint analysis of multiple ChIP-seq libraries with application to histone modification. Stat Appl Genet Mol Biol. 2012 Feb 10; 2012 Feb 10. PMID: 22499701

Qian F, Wang X, Zhang L, Chen S, Piecychna M, Allore H, Bockenstedt L, Malawista S, Bucala R, Shaw AC, Fikrig E, Montgomery RR: Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly. Aging Cell. 2012 Feb; 2011 Nov 28. PMID: 22023165

Li G, Gelernter J, Kranzler HR, Zhao H: M(3): an improved SNP calling algorithm for Illumina BeadArray data. Bioinformatics. 2012 Feb 1; 2011 Dec 8. PMID: 22155947

Van Ness PH, Murphy TE, Araujo KL, Pisani MA: Multivariate graphical methods provide an insightful way to formulate explanatory hypotheses from limited categorical data. J Clin Epidemiol. 2012 Feb; 2011 Sep 1. PMID: 21889310

Gill TM, Gahbauer EA, Murphy TE, Han L, Allore HG: Risk factors and precipitants of long-term disability in community mobility: a cohort study of older persons. Ann Intern Med. 2012 Jan 17. PMID: 22250144

Vaz Fragoso CA, Enright PL, McAvay G, Van Ness PH, Gill TM: Frailty and respiratory impairment in older persons. Am J Med. 2012 Jan. PMID: 22195532

Han L, Kim N, Brandt C, Allore HG: Antidepressant use and cognitive deficits in older men: addressing confounding by indications with different methods. Ann Epidemiol. 2012 Jan; 2011 Oct 28. PMID: 22037381

Li B, Chuns H, Zhao H: Sparse Estimation of Conditional Graphical Models With Application to Gene Networks. J Am Stat Assoc. 2012 Jan 1. PMID: 24574574

Zuo L, Gelernter J, Zhang CK, Zhao H, Lu L, Kranzler HR, Malison RT, Li CS, Wang F, Zhang XY, Deng HW, Krystal JH, Zhang F, Luo X: Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology. 2012 Jan; 2011 Sep 28. PMID: 21956439

Fried TR, Redding CA, Robbins ML, Paiva A, O'Leary JR, Iannone L: Promoting advance care planning as health behavior change: development of scales to assess Decisional Balance, Medical and Religious Beliefs, and Processes of Change. Patient Educ Couns. 2012 Jan; 2011 Jul 7. PMID: 21741194

Zhang W, Ferguson J, Ng SM, Hui K, Goh G, Lin A, Esplugues E, Flavell RA, Abraham C, Zhao H, Cho JH: Effector CD4+ T cell expression signatures and immune-mediated disease associated genes. PLoS One. 2012; 2012 Jun 8. PMID: 22715389

Murphy TE, Van Ness PH, Araujo KL, Pisani MA: Bayesian time-series analysis of a repeated-measures poisson outcome with excess zeroes. Am J Epidemiol. 2011 Dec 1; 2011 Oct 24. PMID: 22025357

Gross CP, Soulos PR, Ross JS, Cramer LD, Guerrero C, Tinetti ME, Braithwaite RS: Assessing the impact of screening colonoscopy on mortality in the medicare population. J Gen Intern Med. 2011 Dec; 2011 Aug 13. PMID: 21842323

Li G, Ferguson J, Zheng W, Lee JS, Zhang X, Li L, Kang J, Yan X, Zhao H: Large-scale risk prediction applied to Genetic Analysis Workshop 17 mini-exome sequence data. BMC Proc. 2011 Nov 29; 2011 Nov 29. PMID: 22373389

Yan X, Li L, Lee JS, Zheng W, Ferguson J, Zhao H: Detecting functional rare variants by collapsing and incorporating functional annotation in Genetic Analysis Workshop 17 mini-exome data. BMC Proc. 2011 Nov 29; 2011 Nov 29. PMID: 22373324

Kang J, Zheng W, Li L, Lee JS, Yan X, Zhao H: Use of Bayesian networks to dissect the complexity of genetic disease: application to the Genetic Analysis Workshop 17 simulated data. BMC Proc. 2011 Nov 29; 2011 Nov 29. PMID: 22373110

Gill TM, Gahbauer EA, Han L, Allore HG: The relationship between intervening hospitalizations and transitions between frailty states. J Gerontol A Biol Sci Med Sci. 2011 Nov; 2011 Aug 17. PMID: 21852286

Vaz Fragoso CA, Gill TM, McAvay G, Van Ness PH, Yaggi HK, Concato J: Use of lambda-mu-sigma-derived Z score for evaluating respiratory impairment in middle-aged persons. Respir Care. 2011 Nov; 2011 May 20. PMID: 21605489

Fraenkel L, Street RL Jr, Fried TR: Development of a tool to improve the quality of decision making in atrial fibrillation. BMC Med Inform Decis Mak. 2011 Oct 6; 2011 Oct 6. PMID: 21977943

Carlson Scholz JA, Garg R, Compton SR, Allore HG, Zeiss CJ, Uchio EM: Poliomyelitis in MuLV-infected ICR-SCID mice after injection of basement membrane matrix contaminated with lactate dehydrogenase-elevating virus. Comp Med. 2011 Oct. PMID: 22330347

Fragoso CA, Concato J, McAvay G, Yaggi HK, Van Ness PH, Gill TM: Staging the severity of chronic obstructive pulmonary disease in older persons based on spirometric Z-scores. J Am Geriatr Soc. 2011 Oct; 2011 Sep 13. PMID: 22091498

Vaz Fragoso CA, Gill TM, McAvay G, Yaggi HK, Van Ness PH, Concato J: Respiratory impairment and mortality in older persons: a novel spirometric approach. J Investig Med. 2011 Oct. PMID: 22011620

Van Ness PH, Fried TR, Gill TM: Mixed Methods for the Interpretation of Longitudinal Gerontologic Data: Insights From Philosophical Hermeneutics. J Mix Methods Res. 2011 Oct; 2011 Jul 13. PMID: 22582035

Erekson EA, Yip SO, Ciarleglio MM, Fried TR: Postoperative complications after gynecologic surgery. Obstet Gynecol. 2011 Oct. PMID: 21934441

Kato M, Chen X, Inukai S, Zhao H, Slack FJ: Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans. RNA. 2011 Oct; 2011 Aug 2. PMID: 21810936

Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H, Gelernter J: Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry. 2011 Sep 15; 2011 Jun 17. PMID: 21683344

Li D, Zhao H, Gelernter J: Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases. Biol Psychiatry. 2011 Sep 15; 2011 Apr 17. PMID: 21497796

Barry LC, Murphy TE, Gill TM: Depressive symptoms and functional transitions over time in older persons. Am J Geriatr Psychiatry. 2011 Sep. PMID: 21873834

Chun H, Ballard DH, Cho J, Zhao H: Identification of association between disease and multiple markers via sparse partial least-squares regression. Genet Epidemiol. 2011 Sep; 2011 Jun 15. PMID: 21678491

Tinetti ME, McAvay G, Chang SS, Ning Y, Newman AB, Fitzpatrick A, Fried TR, Harris TB, Nevitt MC, Satterfield S, Yaffe K, Peduzzi P: Effect of chronic disease-related symptoms and impairments on universal health outcomes in older adults. J Am Geriatr Soc. 2011 Sep; 2011 Aug 24. PMID: 21883120

Tinetti ME, McAvay GJ, Chang SS, Newman AB, Fitzpatrick AL, Fried TR, Peduzzi PN: Contribution of multiple chronic conditions to universal health outcomes. J Am Geriatr Soc. 2011 Sep; 2011 Aug 30. PMID: 21883118

Chaudhry SI, McAvay G, Ning Y, Allore HG, Newman AB, Gill TM: Risk factors for onset of disability among older persons newly diagnosed with heart failure: the Cardiovascular Health Study. J Card Fail. 2011 Sep. PMID: 21872147

Han L, McCusker J, Cole M, Capek R, Abrahamowicz M: Antidepressant use and cognitive functioning in older medical patients with major or minor depression: a prospective cohort study with database linkage. J Clin Psychopharmacol. 2011 Aug. PMID: 21694621

Zheng W, Chung LM, Zhao H: Bias detection and correction in RNA-Sequencing data. BMC Bioinformatics. 2011 Jul 19; 2011 Jul 19. PMID: 21771300

Shaw AC, Panda A, Joshi SR, Qian F, Allore HG, Montgomery RR: Dysregulation of human Toll-like receptor function in aging. Ageing Res Rev. 2011 Jul; 2010 Nov 10. PMID: 21074638

Barry LC, Murphy TE, Gill TM: Depression and functional recovery after a disabling hospitalization in older persons. J Am Geriatr Soc. 2011 Jul; 2011 Jun 13. PMID: 21668916

Tinetti ME, Studenski SA: Comparative effectiveness research and patients with multiple chronic conditions. N Engl J Med. 2011 Jun 30; 2011 Jun 22. PMID: 21696327

Kang J, Kugathasan S, Georges M, Zhao H, Cho JH, NIDDK IBD Genetics Consortium: Improved risk prediction for Crohn's disease with a multi-locus approach. Hum Mol Genet. 2011 Jun 15; 2011 Mar 22. PMID: 21427131

Fried TR, Redding CA, Robbins ML, O'Leary JR, Iannone L: Agreement between older persons and their surrogate decision-makers regarding participation in advance care planning. J Am Geriatr Soc. 2011 Jun; 2011 Jun 7. PMID: 21649619

Fried TR, Tinetti ME, Towle V, O'Leary JR, Iannone L: Effects of benefits and harms on older persons' willingness to take medication for primary cardiovascular prevention. Arch Intern Med. 2011 May 23; 2011 Feb 28. PMID: 21357797

Qian F, Wang X, Zhang L, Lin A, Zhao H, Fikrig E, Montgomery RR: Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus. J Infect Dis. 2011 May 15; 2011 Mar 11. PMID: 21398396

Ma H, Schadt EE, Kaplan LM, Zhao H: COSINE: COndition-SpecIfic sub-NEtwork identification using a global optimization method. Bioinformatics. 2011 May 1; 2011 Mar 16. PMID: 21414987

Fried TR, Tinetti M, Agostini J, Iannone L, Towle V: Health outcome prioritization to elicit preferences of older persons with multiple health conditions. Patient Educ Couns. 2011 May; 2010 May 31. PMID: 20570078

Quagliarello V: Dissemination of Neisseria meningitidis. N Engl J Med. 2011 Apr 21. PMID: 21506747

Lee JS, Choi M, Yan X, Lifton RP, Zhao H: On optimal pooling designs to identify rare variants through massive resequencing. Genet Epidemiol. 2011 Apr; 2011 Jan 19. PMID: 21254222

Makris UE, Fraenkel L, Han L, Leo-Summers L, Gill TM: Epidemiology of restricting back pain in community-living older persons. J Am Geriatr Soc. 2011 Apr; 2011 Mar 15. PMID: 21410444

Qi X, Zhao H: Some theoretical properties of Silverman's method for Smoothed functional principal component analysis. J Multivar Anal. 2011 Apr 1. PMID: 21516205

Doernberg S, Schaaf B, Dalhoff K, Leng L, Beitin A, Quagliarello V, Bucala R: Association of macrophage migration inhibitory factor (MIF) polymorphisms with risk of meningitis from Streptococcus pneumoniae. Cytokine. 2011 Mar; 2011 Jan 3. PMID: 21208809

Chang X, Liu F, Wang X, Lin A, Zhao H, Su B: The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation. Immunity. 2011 Feb 25; 2011 Feb 17. PMID: 21333552

Vest MT, Murphy TE, Araujo KL, Pisani MA: Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study. Health Qual Life Outcomes. 2011 Feb 5; 2011 Feb 5. PMID: 21294911

Fried TR, Tinetti ME, Iannone L: Primary care clinicians' experiences with treatment decision making for older persons with multiple conditions. Arch Intern Med. 2011 Jan 10; 2010 Sep 13. PMID: 20837819


Zheng W, Gianoulis TA, Karczewski KJ, Zhao H, Snyder M: Regulatory variation within and between species. Annu Rev Genomics Hum Genet. 2011. PMID: 21721942

Li L, Zheng W, Lee JS, Zhang X, Ferguson J, Yan X, Zhao H: Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data. BMC Proc. 2011; 2011 Nov 29. PMID: 22373309

Das R, Towle V, Van Ness PH, Juthani-Mehta M: Adverse outcomes in nursing home residents with increased episodes of observed bacteriuria. Infect Control Hosp Epidemiol. 2011 Jan; 2010 Nov 22. PMID: 21091203

Chang SS, Vaz Fragoso CA, Van Ness PH, Fried LP, Tinetti ME: Association between combined interleukin-6 and C-reactive protein levels and pulmonary function in older women: results from the Women's Health and Aging Studies I and II. J Am Geriatr Soc. 2011 Jan. PMID: 21226682

Zuo L, Zhang CK, Wang F, Li CS, Zhao H, Lu L, Zhang XY, Lu L, Zhang H, Zhang F, Krystal JH, Luo X: A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. PLoS One. 2011; 2011 Nov 7. PMID: 22096494

Berger C, Hoffmann K, Vasquez JG, Mane S, Lewis J, Filler R, Lin A, Zhao H, Durazzo T, Baird A, Lin W, Foss F, Christensen I, Girardi M, Tigelaar R, Edelson R: Rapid generation of maturationally synchronized human dendritic cells: contribution to the clinical efficacy of extracorporeal photochemotherapy. Blood. 2010 Dec 2; 2010 Aug 18. PMID: 20720185

Peduzzi P, Kyriakides T, O'Connor TZ, Guarino P, Warren SR, Huang GD: Methodological issues in comparative effectiveness research: clinical trials. Am J Med. 2010 Dec. PMID: 21184867

Huang S, Tong T, Zhao H: Bias-corrected diagonal discriminant rules for high-dimensional classification. Biometrics. 2010 Dec. PMID: 20222939

Beech RD, Lowthert L, Leffert JJ, Mason PN, Taylor MM, Umlauf S, Lin A, Lee JY, Maloney K, Muralidharan A, Lorberg B, Zhao H, Newton SS, Mane S, Epperson CN, Sinha R, Blumberg H, Bhagwagar Z: Increased peripheral blood expression of electron transport chain genes in bipolar depression. Bipolar Disord. 2010 Dec. PMID: 21176028

Fried TR, Redding CA, Robbins ML, Paiva A, O'Leary JR, Iannone L: Stages of change for the component behaviors of advance care planning. J Am Geriatr Soc. 2010 Dec. PMID: 21143441

Lipska KJ, De Rekeneire N, Van Ness PH, Johnson KC, Kanaya A, Koster A, Strotmeyer ES, Goodpaster BH, Harris T, Gill TM, Inzucchi SE: Identifying dysglycemic states in older adults: implications of the emerging use of hemoglobin A1c. J Clin Endocrinol Metab. 2010 Dec; 2010 Sep 22. PMID: 20861123

Mistry PK, Liu J, Yang M, Nottoli T, McGrath J, Jain D, Zhang K, Keutzer J, Chuang WL, Mehal WZ, Zhao H, Lin A, Mane S, Liu X, Peng YZ, Li JH, Agrawal M, Zhu LL, Blair HC, Robinson LJ, Iqbal J, Sun L, Zaidi M: Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proc Natl Acad Sci U S A. 2010 Nov 9; 2010 Oct 20. PMID: 20962279

Gill TM, Allore HG, Gahbauer EA, Murphy TE: Change in disability after hospitalization or restricted activity in older persons. JAMA. 2010 Nov 3. PMID: 21045098

Juthani-Mehta M, Quagliarello VJ: Infectious diseases in the nursing home setting: challenges and opportunities for clinical investigation. Clin Infect Dis. 2010 Oct 15. PMID: 20822459

Santoro N, Kursawe R, D'Adamo E, Dykas DJ, Zhang CK, Bale AE, Calí AM, Narayan D, Shaw MM, Pierpont B, Savoye M, Lartaud D, Eldrich S, Cushman SW, Zhao H, Shulman GI, Caprio S: A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. Hepatology. 2010 Oct. PMID: 20803499

Gill TM: Assessment of function and disability in longitudinal studies. J Am Geriatr Soc. 2010 Oct. PMID: 21029059

Vaz Fragoso CA, Araujo KL, Van Ness PH, Marottoli RA: Sleep disturbances and adverse driving events in a predominantly male cohort of active older drivers. J Am Geriatr Soc. 2010 Oct. PMID: 20929465

Dávalos A, Fernández-Hernando C, Sowa G, Derakhshan B, Lin MI, Lee JY, Zhao H, Luo R, Colangelo C, Sessa WC: Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells. Mol Cell Proteomics. 2010 Oct; 2010 Jun 28. PMID: 20585024

Chaudhry SI, McAvay G, Ning Y, Allore HG, Newman AB, Gill TM: Geriatric impairments and disability: the cardiovascular health study. J Am Geriatr Soc. 2010 Sep. PMID: 20863328

Hu JX, Zhao H, Zhou HH: False Discovery Rate Control With Groups. J Am Stat Assoc. 2010 Sep 1. PMID: 21931466

Pisani MA, Murphy TE, Araujo KL, Van Ness PH: Factors associated with persistent delirium after intensive care unit admission in an older medical patient population. J Crit Care. 2010 Sep; 2010 Apr 22. PMID: 20413252

Shaw AC, Joshi S, Greenwood H, Panda A, Lord JM: Aging of the innate immune system. Curr Opin Immunol. 2010 Aug. PMID: 20667703

Concato J, Peduzzi P, Huang GD, O'Leary TJ, Kupersmith J: Comparative effectiveness research: what kind of studies do we need? J Investig Med. 2010 Aug. PMID: 20479661

Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK, Gill TM: Chronic obstructive pulmonary disease in older persons: A comparison of two spirometric definitions. Respir Med. 2010 Aug; 2010 Mar 3. PMID: 20199857

Van Ness PH, Charpentier PA, Ip EH, Leng X, Murphy TE, Tooze JA, Allore HG: Gerontologic biostatistics: the statistical challenges of clinical research with older study participants. J Am Geriatr Soc. 2010 Jul; 2010 Jun 1. PMID: 20533963

Dunne DW, Shaw A, Bockenstedt LK, Allore HG, Chen S, Malawista SE, Leng L, Mizue Y, Piecychna M, Zhang L, Towle V, Bucala R, Montgomery RR, Fikrig E: Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults. PLoS One. 2010 Jun 28; 2010 Jun 28. PMID: 20596538

Mathai SK, Gulati M, Peng X, Russell TR, Shaw AC, Rubinowitz AN, Murray LA, Siner JM, Antin-Ozerkis DE, Montgomery RR, Reilkoff RA, Bucala RJ, Herzog EL: Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Lab Invest. 2010 Jun; 2010 Apr 19. PMID: 20404807

Zheng W, Zhao H, Mancera E, Steinmetz LM, Snyder M: Genetic analysis of variation in transcription factor binding in yeast. Nature. 2010 Apr 22; 2010 Mar 17. PMID: 20237471

Ballard DH, Cho J, Zhao H: Comparisons of multi-marker association methods to detect association between a candidate region and disease. Genet Epidemiol. 2010 Apr. PMID: 19810024

Gill TM, Gahbauer EA, Han L, Allore HG: Trajectories of disability in the last year of life. N Engl J Med. 2010 Apr 1. PMID: 20357280

Fraenkel L, Fried TR: Individualized medical decision making: necessary, achievable, but not yet attainable. Arch Intern Med. 2010 Mar 22. PMID: 20308644

Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK, Gill TM: The ratio of FEV1 to FVC as a basis for establishing chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Mar 1; 2009 Dec 17. PMID: 20019341

Murphy TE, Gaughan M, Hume R, Moore SG Jr: College Graduation Rates for Minority Students in a Selective Technical University: Will Participation in a Summer Bridge Program Contribute to Success? Educ Eval Policy Anal. 2010 Mar. PMID: 23136456

Ahluwalia SC, Gill TM, Baker DI, Fried TR: Perspectives of older persons on bathing and bathing disability: a qualitative study. J Am Geriatr Soc. 2010 Mar; 2010 Feb 11. PMID: 20158554

Kang J, Cho J, Zhao H: Practical issues in building risk-predicting models for complex diseases. J Biopharm Stat. 2010 Mar. PMID: 20309766

Panda A, Qian F, Mohanty S, van Duin D, Newman FK, Zhang L, Chen S, Towle V, Belshe RB, Fikrig E, Allore HG, Montgomery RR, Shaw AC: Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol. 2010 Mar 1; 2010 Jan 25. PMID: 20100933

Chaudhry SI, Wang Y, Gill TM, Krumholz HM: Geriatric conditions and subsequent mortality in older patients with heart failure. J Am Coll Cardiol. 2010 Jan 26. PMID: 20117435

Fried TR, Drickamer M: Garnering support for advance care planning. JAMA. 2010 Jan 20. PMID: 20085956

Tinetti ME, Kumar C: The patient who falls: "It's always a trade-off". JAMA. 2010 Jan 20. PMID: 20085954

Van Ness PH, Allore HG, Fried TR, Lin H: Inverse intensity weighting in generalized linear models as an option for analyzing longitudinal data with triggered observations. Am J Epidemiol. 2010 Jan 1; 2009 Nov 25. PMID: 19942574

Akgün KM, Murphy TE, Araujo KL, Van Ness PH, Pisani M: Does gender impact intensity of care provided to older medical intensive care unit patients? Crit Care Res Pract. 2010; 2010 Oct 20. PMID: 20981259

Mustavich LF, Miller P, Kidd KK, Zhao H: Using a pharmacokinetic model to relate an individual's susceptibility to alcohol dependence to genotypes. Hum Hered. 2010; 2010 Aug 12. PMID: 20714161

Ballard DH, Aporntewan C, Lee JY, Lee JS, Wu Z, Zhao H: A pathway analysis applied to Genetic Analysis Workshop 16 genome-wide rheumatoid arthritis data. BMC Proc. 2009 Dec 15; 2009 Dec 15. PMID: 20018088

Wu Z, Aporntewan C, Ballard DH, Lee JY, Lee JS, Zhao H: Two-stage joint selection method to identify candidate markers from genome-wide association studies. BMC Proc. 2009 Dec 15; 2009 Dec 15. PMID: 20018019

Aporntewan C, Ballard DH, Lee JY, Lee JS, Wu Z, Zhao H: Gene hunting of the Genetic Analysis Workshop 16 rheumatoid arthritis data using rough set theory. BMC Proc. 2009 Dec 15; 2009 Dec 15. PMID: 20017992

Pisani MA, Kong SY, Kasl SV, Murphy TE, Araujo KL, Van Ness PH: Days of delirium are associated with 1-year mortality in an older intensive care unit population. Am J Respir Crit Care Med. 2009 Dec 1; 2009 Sep 10. PMID: 19745202

Han L: Top cited papers in International Psychogeriatrics: 6c. Tracking cognitive decline in Alzheimer's disease using the Mini-mental State Examination: a meta-analysis ("mini" is not necessarily trivial!). Int Psychogeriatr. 2009 Dec; 2009 Sep 14. PMID: 19747422

Barry LC, Allore HG, Bruce ML, Gill TM: Longitudinal association between depressive symptoms and disability burden among older persons. J Gerontol A Biol Sci Med Sci. 2009 Dec; 2009 Sep 23. PMID: 19776217

Gill TM, Gahbauer EA, Han L, Allore HG: Factors associated with recovery of prehospital function among older persons admitted to a nursing home with disability after an acute hospitalization. J Gerontol A Biol Sci Med Sci. 2009 Dec; 2009 Aug 6. PMID: 19661289

Sun N, Zhao H: Reconstructing transcriptional regulatory networks through genomics data. Stat Methods Med Res. 2009 Dec. PMID: 20048387

Joshi SR, Shaw AC, Quagliarello VJ: Pandemic influenza H1N1 2009, innate immunity, and the impact of immunosenescence on influenza vaccine. Yale J Biol Med. 2009 Dec. PMID: 20027279

Das R, Perrelli E, Towle V, Van Ness PH, Juthani-Mehta M: Antimicrobial susceptibility of bacteria isolated from urine samples obtained from nursing home residents. Infect Control Hosp Epidemiol. 2009 Nov. PMID: 19785518

Vaz Fragoso CA, Gahbauer EA, Van Ness PH, Gill TM: Sleep-wake disturbances and frailty in community-living older persons. J Am Geriatr Soc. 2009 Nov; 2009 Sep 30. PMID: 19793356

Luo R, Colangelo CM, Sessa WC, Zhao H: Bayesian Analysis of iTRAQ Data with Nonrandom Missingness: Identification of Differentially Expressed Proteins. Stat Biosci. 2009 Nov. PMID: 21927625

Gill TM, Van Ness PH, Gahbauer EA: Factors associated with accurate recall of prior disability in older persons. J Am Geriatr Soc. 2009 Oct; 2009 Sep 8. PMID: 19737329

Gill TM, Murphy TE, Barry LC, Allore HG: Risk factors for disability subtypes in older persons. J Am Geriatr Soc. 2009 Oct; 2009 Aug 20. PMID: 19694870

Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK, Gill TM: Defining chronic obstructive pulmonary disease in older persons. Respir Med. 2009 Oct; 2009 May 21. PMID: 19464159

Fried TR, Bullock K, Iannone L, O'Leary JR: Understanding advance care planning as a process of health behavior change. J Am Geriatr Soc. 2009 Sep; 2009 Aug 4. PMID: 19682120

Thomas JM, O'Leary JR, Fried TR: Understanding their options: determinants of hospice discussion for older persons with advanced illness. J Gen Intern Med. 2009 Aug; 2009 Jun 9. PMID: 19506972

Mendu ML, McAvay G, Lampert R, Stoehr J, Tinetti ME: Yield of diagnostic tests in evaluating syncopal episodes in older patients. Arch Intern Med. 2009 Jul 27. PMID: 19636031

Quagliarello V, Juthani-Mehta M, Ginter S, Towle V, Allore H, Tinetti M: Pilot testing of intervention protocols to prevent pneumonia in nursing home residents. J Am Geriatr Soc. 2009 Jul; 2009 Jun 3. PMID: 19558483

Wu Z, Zhao H: Statistical power of model selection strategies for genome-wide association studies. PLoS Genet. 2009 Jul; 2009 Jul 31. PMID: 19649321

Panda A, Arjona A, Sapey E, Bai F, Fikrig E, Montgomery RR, Lord JM, Shaw AC: Human innate immunosenescence: causes and consequences for immunity in old age. Trends Immunol. 2009 Jul; 2009 Jun 21. PMID: 19541535

Gill TM, Gahbauer EA, Van Ness PH: Psychometric properties of a scale to assess the severity of bathing disability. Arch Phys Med Rehabil. 2009 Jun. PMID: 19480875

Juthani-Mehta M, Quagliarello V, Perrelli E, Towle V, Van Ness PH, Tinetti M: Clinical features to identify urinary tract infection in nursing home residents: a cohort study. J Am Geriatr Soc. 2009 Jun. PMID: 19490243

Sampson JN, Zhao H: Genotyping and inflated type I error rate in genome-wide association case/control studies. BMC Bioinformatics. 2009 Feb 23; 2009 Feb 23. PMID: 19236714

Gill TM, Gahbauer EA, Han L, Allore HG: Functional trajectories in older persons admitted to a nursing home with disability after an acute hospitalization. J Am Geriatr Soc. 2009 Feb; 2008 Dec 11. PMID: 19170778

Jiao Y, Tausta SL, Gandotra N, Sun N, Liu T, Clay NK, Ceserani T, Chen M, Ma L, Holford M, Zhang HY, Zhao H, Deng XW, Nelson T: A transcriptome atlas of rice cell types uncovers cellular, functional and developmental hierarchies. Nat Genet. 2009 Feb; 2009 Jan 4. PMID: 19122662

Datta D, Zhao H: Effect of false positive and false negative rates on inference of binding target conservation across different conditions and species from ChIP-chip data. BMC Bioinformatics. 2009 Jan 19; 2009 Jan 19. PMID: 19152696

Holford ME, Rajeevan H, Zhao H, Kidd KK, Cheung KH: Semantic Web-based integration of cancer pathways and allele frequency data. Cancer Inform. 2009 Jan 15; 2009 Jan 15. PMID: 19458791

Pisani MA, Murphy TE, Araujo KL, Slattum P, Van Ness PH, Inouye SK: Benzodiazepine and opioid use and the duration of intensive care unit delirium in an older population. Crit Care Med. 2009 Jan. PMID: 19050611

Sampson J, Zhao H: Identifying individuals in a complex mixture of DNA with unknown ancestry. Stat Appl Genet Mol Biol. 2009; 2009 Sep 9. PMID: 19799556

Budel S, Padukkavidana T, Liu BP, Feng Z, Hu F, Johnson S, Lauren J, Park JH, McGee AW, Liao J, Stillman A, Kim JE, Yang BZ, Sodi S, Gelernter J, Zhao H, Hisama F, Arnsten AF, Strittmatter SM: Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci. 2008 Dec 3. PMID: 19052207

Yang BZ, Kranzler HR, Zhao H, Gruen JR, Luo X, Gelernter J: Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence. Alcohol Clin Exp Res. 2008 Dec; 2008 Sep 30. PMID: 18828801

Lin H, Guo Z, Peduzzi PN, Gill TM, Allore HG: A semiparametric transition model with latent traits for longitudinal multistate data. Biometrics. 2008 Dec; 2008 Mar 19. PMID: 18355385

Rothman MD, Leo-Summers L, Gill TM: Prognostic significance of potential frailty criteria. J Am Geriatr Soc. 2008 Dec. PMID: 19093920

Han L, Agostini JV, Allore HG: Cumulative anticholinergic exposure is associated with poor memory and executive function in older men. J Am Geriatr Soc. 2008 Dec. PMID: 19093918

Fried TR, McGraw S, Agostini JV, Tinetti ME: Views of older persons with multiple morbidities on competing outcomes and clinical decision-making. J Am Geriatr Soc. 2008 Oct; 2008 Sep 2. PMID: 18771453

Fried TR, O'Leary JR: Using the experiences of bereaved caregivers to inform patient- and caregiver-centered advance care planning. J Gen Intern Med. 2008 Oct; 2008 Jul 30. PMID: 18665427

Han L, McCusker J, Cole M, Abrahamowicz M, Capek R: 12-month cognitive outcomes of major and minor depression in older medical patients. Am J Geriatr Psychiatry. 2008 Sep. PMID: 18757768

Murphy TE, Agostini JV, Van Ness PH, Peduzzi P, Tinetti ME, Allore HG: Assessing multiple medication use with probabilities of benefits and harms. J Aging Health. 2008 Sep; 2008 Jul 14. PMID: 18625759

Lai JM, Gill TM, Cooney LM, Bradley EH, Hawkins KA, Karlawish JH: Everyday decision-making ability in older persons with cognitive impairment. Am J Geriatr Psychiatry. 2008 Aug. PMID: 18669948

Xiang B, Li A, Valentin D, Nowak NJ, Zhao H, Li P: Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay. Am J Med Genet A. 2008 Aug 1. PMID: 18627053

Van Ness PH, Towle VR, O'Leary JR, Fried TR: Religion, risk, and medical decision making at the end of life. J Aging Health. 2008 Aug; 2008 Apr 28. PMID: 18443144

Tinetti ME, McAvay GJ, Fried TR, Allore HG, Salmon JC, Foody JM, Bianco L, Ginter S, Fraenkel L: Health outcome priorities among competing cardiovascular, fall injury, and medication-related symptom outcomes. J Am Geriatr Soc. 2008 Aug; 2008 Jul 24. PMID: 18662210

Tinetti ME, Baker DI, King M, Gottschalk M, Murphy TE, Acampora D, Carlin BP, Leo-Summers L, Allore HG: Effect of dissemination of evidence in reducing injuries from falls. N Engl J Med. 2008 Jul 17. PMID: 18635430

Juthani-Mehta M, Quagliarello V: Five key principles of a successful clinical research career in infectious diseases. Curr Infect Dis Rep. 2008 Jul. PMID: 18765109

Vaz Fragoso CA, Araujo KL, Van Ness PH, Marottoli RA: Prevalence of sleep disturbances in a cohort of older drivers. J Gerontol A Biol Sci Med Sci. 2008 Jul. PMID: 18693226

Tinetti ME: Over-the-counter sales of statins and other drugs for asymptomatic conditions. N Engl J Med. 2008 Jun 19. PMID: 18565867

Fragoso CA, Gahbauer EA, Van Ness PH, Concato J, Gill TM: Peak expiratory flow as a predictor of subsequent disability and death in community-living older persons. J Am Geriatr Soc. 2008 Jun; 2008 Apr 18. PMID: 18422951

Gill TM, Gahbauer EA: Evaluating disability over discrete periods of time. J Gerontol A Biol Sci Med Sci. 2008 Jun. PMID: 18559633

Juthani-Mehta M, Tinetti M, Perrelli E, Towle V, Van Ness PH, Quagliarello V: Interobserver variability in the assessment of clinical criteria for suspected urinary tract infection in nursing home residents. Infect Control Hosp Epidemiol. 2008 May. PMID: 18419369

Ji W, Foo JN, O'Roak BJ, Zhao H, Larson MG, Simon DB, Newton-Cheh C, State MW, Levy D, Lifton RP: Rare independent mutations in renal salt handling genes contribute to blood pressure variation. Nat Genet. 2008 May; 2008 Apr 6. PMID: 18391953

Tinetti ME, McAvay GJ, Fried TR, Foody JM, Bianco L, Ginter S, Fraenkel L: Development of a tool for eliciting patient priority from among competing cardiovascular disease, medication-symptoms, and fall injury outcomes. J Am Geriatr Soc. 2008 Apr; 2008 Feb 11. PMID: 18266842

Mohanty S, Town T, Yagi T, Scheidig C, Kwan KY, Allore HG, Flavell RA, Shaw AC: Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta. Proc Natl Acad Sci U S A. 2008 Apr 1; 2008 Mar 26. PMID: 18367668

Van Ness PH, Towle VR, Juthani-Mehta M: Testing measurement reliability in older populations: methods for informed discrimination in instrument selection and application. J Aging Health. 2008 Mar; 2007 Dec 18. PMID: 18089767

Gill TM, Guo Z, Allore HG: Subtypes of disability in older persons over the course of nearly 8 years. J Am Geriatr Soc. 2008 Mar; 2008 Jan 5. PMID: 18194225

Datta D, Zhao H: Statistical methods to infer cooperative binding among transcription factors in Saccharomyces cerevisiae. Bioinformatics. 2008 Feb 15; 2007 Nov 7. PMID: 17989095

Pang H, Zhao H: Building pathway clusters from Random Forests classification using class votes. BMC Bioinformatics. 2008 Feb 6; 2008 Feb 6. PMID: 18254968

Barry LC, Allore HG, Guo Z, Bruce ML, Gill TM: Higher burden of depression among older women: the effect of onset, persistence, and mortality over time. Arch Gen Psychiatry. 2008 Feb. PMID: 18250255

Bartali B, Frongillo EA, Guralnik JM, Stipanuk MH, Allore HG, Cherubini A, Bandinelli S, Ferrucci L, Gill TM: Serum micronutrient concentrations and decline in physical function among older persons. JAMA. 2008 Jan 23. PMID: 18212315

Yagi T, Giallourakis C, Mohanty S, Scheidig C, Shen J, Zheng H, Xavier RJ, Shaw AC: Defective signal transduction in B lymphocytes lacking presenilin proteins. Proc Natl Acad Sci U S A. 2008 Jan 22; 2008 Jan 14. PMID: 18195359

Allore HG, Murphy TE: An examination of effect estimation in factorial and standardly-tailored designs. Clin Trials. 2008. PMID: 18375650

Singh B, Wilson JH, Vasavada HH, Guo Z, Allore HG, Zeiss CJ: Motor deficits and altered striatal gene expression in aphakia (ak) mice. Brain Res. 2007 Dec 14; 2007 Sep 16. PMID: 17949697

Walke LM, Byers AL, Tinetti ME, Dubin JA, McCorkle R, Fried TR: Range and severity of symptoms over time among older adults with chronic obstructive pulmonary disease and heart failure. Arch Intern Med. 2007 Dec 10. PMID: 18071174

Yang BZ, Kranzler HR, Zhao H, Gruen JR, Luo X, Gelernter J: Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. Hum Mol Genet. 2007 Dec 1; 2007 Aug 30. PMID: 17761687

Dinu V, Zhao H, Miller PL: Integrating domain knowledge with statistical and data mining methods for high-density genomic SNP disease association analysis. J Biomed Inform. 2007 Dec; 2007 Jun 10. PMID: 17625973

Van Ness PH, Murphy TE, Araujo KL, Pisani MA, Allore HG: The use of missingness screens in clinical epidemiologic research has implications for regression modeling. J Clin Epidemiol. 2007 Dec; 2007 Jul 25. PMID: 17998078

Agostini JV, Tinetti ME, Han L, Peduzzi P, Foody JM, Concato J: Association between antihypertensive medication use and non-cardiovascular outcomes in older men. J Gen Intern Med. 2007 Dec; 2007 Sep 25. PMID: 17899299

Vaz Fragoso CA, Gill TM: Sleep complaints in community-living older persons: a multifactorial geriatric syndrome. J Am Geriatr Soc. 2007 Nov; 2007 Oct 3. PMID: 17916123

Gill TM, Han L, Allore HG: Bath aids and the subsequent development of bathing disability in community-living older persons. J Am Geriatr Soc. 2007 Nov; 2007 Oct 3. PMID: 17916117

Cosgriff JA, Pisani M, Bradley EH, O'Leary JR, Fried TR: The association between treatment preferences and trajectories of care at the end-of-life. J Gen Intern Med. 2007 Nov; 2007 Sep 14. PMID: 17874168

Concato J, Aslan M, Palmisano MM, Doebbeling CC, Peduzzi P, Ofek K, Soreq H, Doebbeling B: Acetylcholinesterase activity in veterans of the first Gulf War. J Investig Med. 2007 Nov. PMID: 18062897

Chaudhry SI, Wang Y, Concato J, Gill TM, Krumholz HM: Patterns of weight change preceding hospitalization for heart failure. Circulation. 2007 Oct 2; 2007 Sep 10. PMID: 17846286

Vaz Fragoso CA, Gahbauer EA, Van Ness PH, Gill TM: Reporting peak expiratory flow in older persons. J Gerontol A Biol Sci Med Sci. 2007 Oct. PMID: 17921429

Marottoli RA, Ness PH, Araujo KL, Iannone LP, Acampora D, Charpentier P, Peduzzi P: A randomized trial of an education program to enhance older driver performance. J Gerontol A Biol Sci Med Sci. 2007 Oct. PMID: 17921424

Kim I, Liu Y, Zhao H: Bayesian methods for predicting interacting protein pairs using domain information. Biometrics. 2007 Sep. PMID: 17825014

van Duin D, Shaw AC: Toll-like receptors in older adults. J Am Geriatr Soc. 2007 Sep. PMID: 17767688

Fraenkel L, Rabidou N, Wittink D, Fried T: Improving informed decision-making for patients with knee pain. J Rheumatol. 2007 Sep; 2007 Aug 1. PMID: 17696268

Pisani MA, Murphy TE, Van Ness PH, Araujo KL, Inouye SK: Characteristics associated with delirium in older patients in a medical intensive care unit. Arch Intern Med. 2007 Aug 13-27. PMID: 17698685

Juthani-Mehta M, Tinetti M, Perrelli E, Towle V, Quagliarello V: Role of dipstick testing in the evaluation of urinary tract infection in nursing home residents. Infect Control Hosp Epidemiol. 2007 Jul; 2007 May 17. PMID: 17564998

Juthani-Mehta M, Tinetti M, Perrelli E, Towle V, Van Ness PH, Quagliarello V: Diagnostic accuracy of criteria for urinary tract infection in a cohort of nursing home residents. J Am Geriatr Soc. 2007 Jul. PMID: 17608881

Fried TR, O'Leary J, Van Ness P, Fraenkel L: Inconsistency over time in the preferences of older persons with advanced illness for life-sustaining treatment. J Am Geriatr Soc. 2007 Jul. PMID: 17608872

Rothman MD, Van Ness PH, O'Leary JR, Fried TR: Refusal of medical and surgical interventions by older persons with advanced chronic disease. J Gen Intern Med. 2007 Jul; 2007 May 5. PMID: 17483977

Gross CP, McAvay GJ, Guo Z, Tinetti ME: The impact of chronic illnesses on the use and effectiveness of adjuvant chemotherapy for colon cancer. Cancer. 2007 Jun 15. PMID: 17510973

van Duin D, Allore HG, Mohanty S, Ginter S, Newman FK, Belshe RB, Medzhitov R, Shaw AC: Prevaccine determination of the expression of costimulatory B7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults. J Infect Dis. 2007 Jun 1; 2007 Apr 17. PMID: 17471428

Chou WC, Cooney LM Jr, Van Ness PH, Allore HG, Gill TM: Access to primary care for Medicare beneficiaries. J Am Geriatr Soc. 2007 May. PMID: 17493198

McAvay GJ, Van Ness PH, Bogardus ST Jr, Zhang Y, Leslie DL, Leo-Summers LS, Inouye SK: Depressive symptoms and the risk of incident delirium in older hospitalized adults. J Am Geriatr Soc. 2007 May. PMID: 17493187

Marottoli RA, Allore H, Araujo KL, Iannone LP, Acampora D, Gottschalk M, Charpentier P, Kasl S, Peduzzi P: A randomized trial of a physical conditioning program to enhance the driving performance of older persons. J Gen Intern Med. 2007 May. PMID: 17443366

Dinu V, Miller PL, Zhao H: Evidence for association between multiple complement pathway genes and AMD. Genet Epidemiol. 2007 Apr. PMID: 17266113

Gill TM, Han L, Allore HG: Predisposing factors and precipitants for bathing disability in older persons. J Am Geriatr Soc. 2007 Apr. PMID: 17397431

Fried TR, Van Ness PH, Byers AL, Towle VR, O'Leary JR, Dubin JA: Changes in preferences for life-sustaining treatment among older persons with advanced illness. J Gen Intern Med. 2007 Apr. PMID: 17372799

Agostini JV, Tinetti ME, Han L, McAvay G, Foody JM, Concato J: Effects of statin use on muscle strength, cognition, and depressive symptoms in older adults. J Am Geriatr Soc. 2007 Mar. PMID: 17341246

Lee J, He K, Stolc V, Lee H, Figueroa P, Gao Y, Tongprasit W, Zhao H, Lee I, Deng XW: Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development. Plant Cell. 2007 Mar; 2007 Mar 2. PMID: 17337630

van Duin D, Mohanty S, Thomas V, Ginter S, Montgomery RR, Fikrig E, Allore HG, Medzhitov R, Shaw AC: Age-associated defect in human TLR-1/2 function. J Immunol. 2007 Jan 15. PMID: 17202359

Huang S, Ballard D, Zhao H: The role of heritability in mapping expression quantitative trait loci. BMC Proc. 2007; 2007 Dec 18. PMID: 18466589

Peduzzi P, Guo Z, Marottoli RA, Gill TM, Araujo K, Allore HG: Improved self-confidence was a mechanism of action in two geriatric trials evaluating physical interventions. J Clin Epidemiol. 2007 Jan; 2006 Sep 28. PMID: 17161760

Walke LM, Byers AL, Gallo WT, Endrass J, Fried TR: The association of symptoms with health outcomes in chronically ill adults. J Pain Symptom Manage. 2007 Jan. PMID: 17196907

Lee TS, Mane S, Eid T, Zhao H, Lin A, Guan Z, Kim JH, Schweitzer J, King-Stevens D, Weber P, Spencer SS, Spencer DD, de Lanerolle NC: Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. Mol Med. 2007 Jan-Feb. PMID: 17515952

Gross CP, Andersen MS, Krumholz HM, McAvay GJ, Proctor D, Tinetti ME: Relation between Medicare screening reimbursement and stage at diagnosis for older patients with colon cancer. JAMA. 2006 Dec 20. PMID: 17179458

Tinetti ME, Gordon C, Sogolow E, Lapin P, Bradley EH: Fall-risk evaluation and management: challenges in adopting geriatric care practices. Gerontologist. 2006 Dec. PMID: 17169927

Gross CP, Guo Z, McAvay GJ, Allore HG, Young M, Tinetti ME: Multimorbidity and survival in older persons with colorectal cancer. J Am Geriatr Soc. 2006 Dec. PMID: 17198496

Gross CP, McAvay GJ, Krumholz HM, Paltiel AD, Bhasin D, Tinetti ME: The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening. Ann Intern Med. 2006 Nov 7. PMID: 17088577

Wu SP, Leng L, Feng Z, Liu N, Zhao H, McDonald C, Lee A, Arnett FC, Gregersen PK, Mayes MD, Bucala R: Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis Rheum. 2006 Nov. PMID: 17075815

Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY: A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006 Oct 17; 2006 Oct 17. PMID: 17044933

Gill TM, Guo Z, Allore HG: The epidemiology of bathing disability in older persons. J Am Geriatr Soc. 2006 Oct. PMID: 17038069

Pang H, Lin A, Holford M, Enerson BE, Lu B, Lawton MP, Floyd E, Zhao H: Pathway analysis using random forests classification and regression. Bioinformatics. 2006 Aug 15; 2006 Jun 29. PMID: 16809386

McAvay GJ, Van Ness PH, Bogardus ST Jr, Zhang Y, Leslie DL, Leo-Summers LS, Inouye SK: Older adults discharged from the hospital with delirium: 1-year outcomes. J Am Geriatr Soc. 2006 Aug. PMID: 16913993

Gill TM, Allore HG, Han L: Bathing disability and the risk of long-term admission to a nursing home. J Gerontol A Biol Sci Med Sci. 2006 Aug. PMID: 16912099

Tsubouchi T, Zhao H, Roeder GS: The meiosis-specific zip4 protein regulates crossover distribution by promoting synaptonemal complex formation together with zip2. Dev Cell. 2006 Jun. PMID: 16740482

Guarino P, Lamping DL, Elbourne D, Carpenter J, Peduzzi P: A brief measure of perceived understanding of informed consent in a clinical trial was validated. J Clin Epidemiol. 2006 Jun; 2006 Mar 24. PMID: 16713523

Sun N, Carroll RJ, Zhao H: Bayesian error analysis model for reconstructing transcriptional regulatory networks. Proc Natl Acad Sci U S A. 2006 May 23; 2006 May 15. PMID: 16702552

Gelernter J, Panhuysen C, Wilcox M, Hesselbrock V, Rounsaville B, Poling J, Weiss R, Sonne S, Zhao H, Farrer L, Kranzler HR: Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet. 2006 May; 2006 Mar 16. PMID: 16642432

Fried TR, Byers AL, Gallo WT, Van Ness PH, Towle VR, O'Leary JR, Dubin JA: Prospective study of health status preferences and changes in preferences over time in older adults. Arch Intern Med. 2006 Apr 24. PMID: 16636215

Belcher VN, Fried TR, Agostini JV, Tinetti ME: Views of older adults on patient participation in medication-related decision making. J Gen Intern Med. 2006 Apr. PMID: 16686804

You X, Pan M, Gao W, Shiah HS, Tao J, Zhang D, Koumpouras F, Wang S, Zhao H, Madri JA, Baker D, Cheng YC, Yin Z: Effects of a novel tylophorine analog on collagen-induced arthritis through inhibition of the innate immune response. Arthritis Rheum. 2006 Mar. PMID: 16508970

Zeiss CJ, Allore HG, Towle V, Tao W: CNTF induces dose-dependent alterations in retinal morphology in normal and rcd-1 canine retina. Exp Eye Res. 2006 Mar; 2005 Sep 6. PMID: 16143329

Levy BR, Slade MD, Gill TM: Hearing decline predicted by elders' stereotypes. J Gerontol B Psychol Sci Soc Sci. 2006 Mar. PMID: 16497958

Gill TM, Gahbauer EA, Allore HG, Han L: Transitions between frailty states among community-living older persons. Arch Intern Med. 2006 Feb 27. PMID: 16505261

Yu W, Wu B, Lin N, Stone K, Williams K, Zhao H: Detecting and aligning peaks in mass spectrometry data with applications to MALDI. Comput Biol Chem. 2006 Feb; 2005 Nov 17. PMID: 16298163

Gill TM, Allore HG, Hardy SE, Guo Z: The dynamic nature of mobility disability in older persons. J Am Geriatr Soc. 2006 Feb. PMID: 16460375

Chou WC, Tinetti ME, King MB, Irwin K, Fortinsky RH: Perceptions of physicians on the barriers and facilitators to integrating fall risk evaluation and management into practice. J Gen Intern Med. 2006 Feb; 2005 Dec 7. PMID: 16336618

Fried TR, Bradley EH, O'Leary J: Changes in prognostic awareness among seriously ill older persons and their caregivers. J Palliat Med. 2006 Feb. PMID: 16430346

Concato J, Wells CK, Horwitz RI, Penson D, Fincke G, Berlowitz DR, Froehlich G, Blake D, Vickers MA, Gehr GA, Raheb NH, Sullivan G, Peduzzi P: The effectiveness of screening for prostate cancer: a nested case-control study. Arch Intern Med. 2006 Jan 9. PMID: 16401808

Guarino P, Elbourne D, Carpenter J, Peduzzi P: Consumer involvement in consent document development: a multicenter cluster randomized trial to assess study participants' understanding. Clin Trials. 2006. PMID: 16539087

Pisani MA, Araujo KL, Van Ness PH, Zhang Y, Ely EW, Inouye SK: A research algorithm to improve detection of delirium in the intensive care unit. Crit Care. 2006. PMID: 16919169

Walke LM, Byers AL, McCorkle R, Fried TR: Symptom assessment in community-dwelling older adults with advanced chronic disease. J Pain Symptom Manage. 2006 Jan. PMID: 16442480

Yu W, Wu B, Liu J, Li X, Stone K, Williams KR, Zhao H: MALDI-MS data analysis for disease biomarker discovery. Methods Mol Biol. 2006. PMID: 16785651

Enerson BE, Lin A, Lu B, Zhao H, Lawton MP, Floyd E: Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression. Toxicol Pathol. 2006. PMID: 16507541

van Duin D, Medzhitov R, Shaw AC: Triggering TLR signaling in vaccination. Trends Immunol. 2006 Jan; 2005 Nov 23. PMID: 16310411

Huang S, Wang S, Liu N, Chen L, Oh C, Zhao H: Whole-genome association analysis to identify markers associated with recombination rates using single-nucleotide polymorphisms and microsatellites. BMC Genet. 2005 Dec 30; 2005 Dec 30. PMID: 16451663

Liu N, Chen L, Wang S, Oh C, Zhao H: Comparison of single-nucleotide polymorphisms and microsatellites in inference of population structure. BMC Genet. 2005 Dec 30; 2005 Dec 30. PMID: 16451635

Chen L, Liu N, Wang S, Oh C, Carriero NJ, Zhao H: Whole-genome association studies on alcoholism comparing different phenotypes using single-nucleotide polymorphisms and microsatellites. BMC Genet. 2005 Dec 30; 2005 Dec 30. PMID: 16451589

Oh C, Wang S, Liu N, Chen L, Zhao H: A Bayesian genome screening of maximum number of drinks as an alcoholism phenotype with the new Haseman-Elston method. BMC Genet. 2005 Dec 30; 2005 Dec 30. PMID: 16451573

Gill TM, Gahbauer EA: Overestimation of chronic disability among elderly persons. Arch Intern Med. 2005 Dec 12-26. PMID: 16344420

Barry LC, Gill TM, Kerns RD, Reid MC: Identification of pain-reduction strategies used by community-dwelling older persons. J Gerontol A Biol Sci Med Sci. 2005 Dec. PMID: 16424290

Cherlin E, Fried T, Prigerson HG, Schulman-Green D, Johnson-Hurzeler R, Bradley EH: Communication between physicians and family caregivers about care at the end of life: when do discussions occur and what is said? J Palliat Med. 2005 Dec. PMID: 16351531

Chen L, Zhao H: Negative correlation between compositional symmetries and local recombination rates. Bioinformatics. 2005 Nov 1; 2005 Aug 30. PMID: 16131519

Juthani-Mehta M, Drickamer MA, Towle V, Zhang Y, Tinetti ME, Quagliarello VJ: Nursing home practitioner survey of diagnostic criteria for urinary tract infections. J Am Geriatr Soc. 2005 Nov. PMID: 16274383

Huang T, Wu B, Lizardi P, Zhao H: Detection of DNA copy number alterations using penalized least squares regression. Bioinformatics. 2005 Oct 15; 2005 Aug 30. PMID: 16131523

Yang BZ, Zhao H, Kranzler HR, Gelernter J: Characterization of a likelihood based method and effects of markers informativeness in evaluation of admixture and population group assignment. BMC Genet. 2005 Oct 14; 2005 Oct 14. PMID: 16225681

Goldstein NE, Concato J, Bradley EH, O'Leary JR, Fried TR: Doctor-patient communication about prognosis: the influence of race and financial status. J Palliat Med. 2005 Oct. PMID: 16238512

Ma L, Chen C, Liu X, Jiao Y, Su N, Li L, Wang X, Cao M, Sun N, Zhang X, Bao J, Li J, Pedersen S, Bolund L, Zhao H, Yuan L, Wong GK, Wang J, Deng XW, Wang J: A microarray analysis of the rice transcriptome and its comparison to Arabidopsis. Genome Res. 2005 Sep. PMID: 16140994

Naik AD, Gill TM: Underutilization of environmental adaptations for bathing in community-living older persons. J Am Geriatr Soc. 2005 Sep. PMID: 16137278

Liu Y, Liu N, Zhao H: Inferring protein-protein interactions through high-throughput interaction data from diverse organisms. Bioinformatics. 2005 Aug 1; 2005 May 19. PMID: 15905281

Gill TM, Allore H, Hardy SE, Holford TR, Han L: Estimates of active and disabled life expectancy based on different assessment intervals. J Gerontol A Biol Sci Med Sci. 2005 Aug. PMID: 16127105

Zou G, Zhao H: Family-based association tests for different family structures using pooled DNA. Ann Hum Genet. 2005 Jul. PMID: 15996171

Gulcicek EE, Colangelo CM, McMurray W, Stone K, Williams K, Wu T, Zhao H, Spratt H, Kurosky A, Wu B: Proteomics and the analysis of proteomic data: an overview of current protein-profiling technologies. Curr Protoc Bioinformatics. 2005 Jul. PMID: 18428746

Jiao Y, Jia P, Wang X, Su N, Yu S, Zhang D, Ma L, Feng Q, Jin Z, Li L, Xue Y, Cheng Z, Zhao H, Han B, Deng XW: A tiling microarray expression analysis of rice chromosome 4 suggests a chromosome-level regulation of transcription. Plant Cell. 2005 Jun; 2005 Apr 29. PMID: 15863518

Mor G, Visintin I, Lai Y, Zhao H, Schwartz P, Rutherford T, Yue L, Bray-Ward P, Ward DC: Serum protein markers for early detection of ovarian cancer. Proc Natl Acad Sci U S A. 2005 May 24; 2005 May 12. PMID: 15890779

Yang BZ, Zhao H, Kranzler HR, Gelernter J: Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE. Genet Epidemiol. 2005 May. PMID: 15782414

Ma L, Sun N, Liu X, Jiao Y, Zhao H, Deng XW: Organ-specific expression of Arabidopsis genome during development. Plant Physiol. 2005 May. PMID: 15888681

Holford M, Li N, Nadkarni P, Zhao H: VitaPad: visualization tools for the analysis of pathway data. Bioinformatics. 2005 Apr 15; 2004 Nov 25. PMID: 15564306

Tinetti ME, Allore H, Araujo KL, Seeman T: Modifiable impairments predict progressive disability among older persons. J Aging Health. 2005 Apr. PMID: 15750053

Baker DI, King MB, Fortinsky RH, Graff LG 4th, Gottschalk M, Acampora D, Preston J, Brown CJ, Tinetti ME: Dissemination of an evidence-based multicomponent fall risk-assessment and -management strategy throughout a geographic area. J Am Geriatr Soc. 2005 Apr. PMID: 15817016

Chen L, Zhao H: Gene expression analysis reveals that histone deacetylation sites may serve as partitions of chromatin gene expression domains. BMC Genomics. 2005 Mar 23; 2005 Mar 23. PMID: 15788094

Zhang SS, Xu X, Li J, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY: Comprehensive in silico functional specification of mouse retina transcripts. BMC Genomics. 2005 Mar 18; 2005 Mar 18. PMID: 15777472

Hardy SE, Dubin JA, Holford TR, Gill TM: Transitions between states of disability and independence among older persons. Am J Epidemiol. 2005 Mar 15. PMID: 15746474

Kernan WN, Quagliarello V, Green ML: Student faculty rounds: a peer-mediated learning activity for internal medicine clerkships. Med Teach. 2005 Mar. PMID: 16019334

Kernan WN, Viscoli CM, Brass LM, Gill TM, Sarrel PM, Horwitz RI: Decline in physical performance among women with a recent transient ischemic attack or ischemic stroke: opportunities for functional preservation a report of the Women's Estrogen Stroke Trial. Stroke. 2005 Mar; 2005 Jan 27. PMID: 15677573

Allore H, Tinetti ME, Araujo KL, Hardy S, Peduzzi P: A case study found that a regression tree outperformed multiple linear regression in predicting the relationship between impairments and Social and Productive Activities scores. J Clin Epidemiol. 2005 Feb. PMID: 15680749

Chen JH, Gill TM, Prigerson HG: Health behaviors associated with better quality of life for older bereaved persons. J Palliat Med. 2005 Feb. PMID: 15662178

Hardy SE, Gill TM: Factors associated with recovery of independence among newly disabled older persons. Arch Intern Med. 2005 Jan 10. PMID: 15642885

Quagliarello V, Ginter S, Han L, Van Ness P, Allore H, Tinetti M: Modifiable risk factors for nursing home-acquired pneumonia. Clin Infect Dis. 2005 Jan 1; 2004 Dec 1. PMID: 15614684

Allore HG, Tinetti ME, Gill TM, Peduzzi PN: Experimental designs for multicomponent interventions among persons with multifactorial geriatric syndromes. Clin Trials. 2005. PMID: 16279575

Fried TR, Bradley EH, O'Leary JR, Byers AL: Unmet desire for caregiver-patient communication and increased caregiver burden. J Am Geriatr Soc. 2005 Jan. PMID: 15667377

Carriero N, Osier MV, Cheung KH, Miller PL, Gerstein M, Zhao H, Wu B, Rifkin S, Chang J, Zhang H, White K, Williams K, Schultz M: A high productivity/low maintenance approach to high-performance computation for biomedicine: four case studies. J Am Med Inform Assoc. 2005 Jan-Feb; 2004 Oct 18. PMID: 15492032

Tinetti ME, Bogardus ST Jr, Agostini JV: Potential pitfalls of disease-specific guidelines for patients with multiple conditions. N Engl J Med. 2004 Dec 30. PMID: 15625341

Liu N, Sawyer SL, Mukherjee N, Pakstis AJ, Kidd JR, Kidd KK, Brookes AJ, Zhao H: Haplotype block structures show significant variation among populations. Genet Epidemiol. 2004 Dec. PMID: 15389924

Walke LM, Gallo WT, Tinetti ME, Fried TR: The burden of symptoms among community-dwelling older persons with advanced chronic disease. Arch Intern Med. 2004 Nov 22. PMID: 15557410

Lai Y, Wu B, Chen L, Zhao H: A statistical method for identifying differential gene-gene co-expression patterns. Bioinformatics. 2004 Nov 22; 2004 Jul 1. PMID: 15231528

Wilson FH, Hariri A, Farhi A, Zhao H, Petersen KF, Toka HR, Nelson-Williams C, Raja KM, Kashgarian M, Shulman GI, Scheinman SJ, Lifton RP: A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science. 2004 Nov 12; 2004 Oct 21. PMID: 15498972

Gill TM, Allore HG, Holford TR, Guo Z: Hospitalization, restricted activity, and the development of disability among older persons. JAMA. 2004 Nov 3. PMID: 15523072

Liu Y, Zhao H: A computational approach for ordering signal transduction pathway components from genomics and proteomics Data. BMC Bioinformatics. 2004 Oct 25; 2004 Oct 25. PMID: 15504238

Gill TM, Allore H, Holford TR, Guo Z: The development of insidious disability in activities of daily living among community-living older persons. Am J Med. 2004 Oct 1. PMID: 15464705

Agostini JV, Han L, Tinetti ME: The relationship between number of medications and weight loss or impaired balance in older adults. J Am Geriatr Soc. 2004 Oct. PMID: 15450051

Rosenbaum JR, Bravata DM, Concato J, Brass LM, Kim N, Fried TR: Informed consent for thrombolytic therapy for patients with acute ischemic stroke treated in routine clinical practice. Stroke. 2004 Sep; 2004 Jul 8. PMID: 15243145

Hoek K, Rimm DL, Williams KR, Zhao H, Ariyan S, Lin A, Kluger HM, Berger AJ, Cheng E, Trombetta ES, Wu T, Niinobe M, Yoshikawa K, Hannigan GE, Halaban R: Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res. 2004 Aug 1. PMID: 15289333

Levy BR, Kasl SV, Gill TM: Image of aging scale. Percept Mot Skills. 2004 Aug. PMID: 15446647

Gill TM, Baker DI, Gottschalk M, Peduzzi PN, Allore H, Van Ness PH: A prehabilitation program for the prevention of functional decline: effect on higher-level physical function. Arch Phys Med Rehabil. 2004 Jul. PMID: 15241748

Gill TM, Allore H, Guo Z: The deleterious effects of bed rest among community-living older persons. J Gerontol A Biol Sci Med Sci. 2004 Jul. PMID: 15304541

Marathe R, Guan Z, Anandalakshmi R, Zhao H, Dinesh-Kumar SP: Study of Arabidopsis thaliana resistome in response to cucumber mosaic virus infection using whole genome microarray. Plant Mol Biol. 2004 Jul. PMID: 15604696

Zou G, Zhao H: The estimation of sibling genetic risk parameters revisited. Genet Epidemiol. 2004 May. PMID: 15095388

Gill TM, McDermott MM, Ibrahim SA, Petersen LA, Doebbeling BN: Getting funded. Career development awards for aspiring clinical investigators. J Gen Intern Med. 2004 May. PMID: 15109347

Fraenkel L, Wittink DR, Concato J, Fried T: Informed choice and the widespread use of antiinflammatory drugs. Arthritis Rheum. 2004 Apr 15. PMID: 15077261

Hardy SE, Gill TM: Recovery from disability among community-dwelling older persons. JAMA. 2004 Apr 7. PMID: 15069047

Goldstein NE, Concato J, Fried TR, Kasl SV, Johnson-Hurzeler R, Bradley EH: Factors associated with caregiver burden among caregivers of terminally ill patients with cancer. J Palliat Care. 2004 Spring. PMID: 15132075

Juthani-Mehta M, Quagliarello VJ: Prognostic scoring systems for infectious diseases: their applicability to the care of older adults. Clin Infect Dis. 2004 Mar 1; 2004 Feb 17. PMID: 14986254

Fraenkel L, Wittink DR, Concato J, Fried T: Are preferences for cyclooxygenase-2 inhibitors influenced by the certainty effect? J Rheumatol. 2004 Mar. PMID: 14994409

Sun N, Zhao H: Genomic approaches in dissecting complex biological pathways. Pharmacogenomics. 2004 Mar. PMID: 15016608

Gao Y, Li J, Strickland E, Hua S, Zhao H, Chen Z, Qu L, Deng XW: An arabidopsis promoter microarray and its initial usage in the identification of HY5 binding targets in vitro. Plant Mol Biol. 2004 Mar. PMID: 15356388

Goh CS, Lan N, Douglas SM, Wu B, Echols N, Smith A, Milburn D, Montelione GT, Zhao H, Gerstein M: Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis. J Mol Biol. 2004 Feb 6. PMID: 14741208

Tinetti ME, Fried T: The end of the disease era. Am J Med. 2004 Feb 1. PMID: 14749162

Hardy SE, Concato J, Gill TM: Resilience of community-dwelling older persons. J Am Geriatr Soc. 2004 Feb. PMID: 14728637

Xia Y, Yu H, Jansen R, Seringhaus M, Baxter S, Greenbaum D, Zhao H, Gerstein M: Analyzing cellular biochemistry in terms of molecular networks. Annu Rev Biochem. 2004. PMID: 15189167

Zou G, Zhao H: The impacts of errors in individual genotyping and DNA pooling on association studies. Genet Epidemiol. 2004 Jan. PMID: 14691952

Van Ness PH, Davis WR, Johnson BD: Socioeconomic marginality and health services utilization among Central Harlem substance users. Subst Use Misuse. 2004 Jan. PMID: 15002944

Vikram HR, Buenconsejo J, Hasbun R, Quagliarello VJ: Impact of valve surgery on 6-month mortality in adults with complicated, left-sided native valve endocarditis: a propensity analysis. JAMA. 2003 Dec 24. PMID: 14693873

Gill TM, Kurland BF: Prognostic effect of prior disability episodes among nondisabled community-living older persons. Am J Epidemiol. 2003 Dec 1. PMID: 14630605

Jiao Y, Yang H, Ma L, Sun N, Yu H, Liu T, Gao Y, Gu H, Chen Z, Wada M, Gerstein M, Zhao H, Qu LJ, Deng XW: A genome-wide analysis of blue-light regulation of Arabidopsis transcription factor gene expression during seedling development. Plant Physiol. 2003 Dec; 2003 Nov 6. PMID: 14605227

Pan D, Sun N, Cheung KH, Guan Z, Ma L, Holford M, Deng X, Zhao H: PathMAPA: a tool for displaying gene expression and performing statistical tests on metabolic pathways at multiple levels for Arabidopsis. BMC Bioinformatics. 2003 Nov 7; 2003 Nov 7. PMID: 14604444

Wang S, Zhao H: Sample size needed to detect gene-gene interactions using association designs. Am J Epidemiol. 2003 Nov 1. PMID: 14585768

Sun N, Ma L, Pan D, Zhao H, Deng XW: Evaluation of light regulatory potential of Calvin cycle steps based on large-scale gene expression profiling data. Plant Mol Biol. 2003 Nov. PMID: 15010613

Zheng L, Wang S, Romans P, Zhao H, Luna C, Benedict MQ: Quantitative trait loci in Anopheles gambiae controlling the encapsulation response against Plasmodium cynomolgi Ceylon. BMC Genet. 2003 Oct 24; 2003 Oct 24. PMID: 14577840

Fried TR, Bradley EH, O'Leary J: Prognosis communication in serious illness: perceptions of older patients, caregivers, and clinicians. J Am Geriatr Soc. 2003 Oct. PMID: 14511159

Fried TR, Bradley EH, Towle VR: Valuing the outcomes of treatment: do patients and their caregivers agree? Arch Intern Med. 2003 Sep 22. PMID: 14504121

Wu B, Abbott T, Fishman D, McMurray W, Mor G, Stone K, Ward D, Williams K, Zhao H: Comparison of statistical methods for classification of ovarian cancer using mass spectrometry data. Bioinformatics. 2003 Sep 1. PMID: 12967959

Garcia-Rostan G, Zhao H, Camp RL, Pollan M, Herrero A, Pardo J, Wu R, Carcangiu ML, Costa J, Tallini G: ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer. J Clin Oncol. 2003 Sep 1. PMID: 12947056

Sun LV, Chen L, Greil F, Negre N, Li TR, Cavalli G, Zhao H, Van Steensel B, White KP: Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila. Proc Natl Acad Sci U S A. 2003 Aug 5; 2003 Jul 22. PMID: 12876199

Luo X, Kranzler HR, Zhao H, Gelernter J: Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans. Am J Med Genet B Neuropsychiatr Genet. 2003 Jul 1. PMID: 12815747

Zou G, Pan D, Zhao H: Genotyping error detection through tightly linked markers. Genetics. 2003 Jul. PMID: 12871922

Wikonkal NM, Remenyik E, Knezevic D, Zhang W, Liu M, Zhao H, Berton TR, Johnson DG, Brash DE: Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice. Nat Cell Biol. 2003 Jul. PMID: 12833065

Gill TM, Allore H, Guo Z: Restricted activity and functional decline among community-living older persons. Arch Intern Med. 2003 Jun 9. PMID: 12796067

Byers AL, Allore H, Gill TM, Peduzzi PN: Application of negative binomial modeling for discrete outcomes: a case study in aging research. J Clin Epidemiol. 2003 Jun. PMID: 12873651

Bogardus ST Jr, Desai MM, Williams CS, Leo-Summers L, Acampora D, Inouye SK: The effects of a targeted multicomponent delirium intervention on postdischarge outcomes for hospitalized older adults. Am J Med. 2003 Apr 1. PMID: 12714128

Fried TR, Bradley EH: What matters to seriously ill older persons making end-of-life treatment decisions?: A qualitative study. J Palliat Med. 2003 Apr. PMID: 12854940

Gill TM, Baker DI, Gottschalk M, Gahbauer EA, Charpentier PA, de Regt PT, Wallace SJ: A prehabilitation program for physically frail community-living older persons. Arch Phys Med Rehabil. 2003 Mar. PMID: 12638108

Ma L, Zhao H, Deng XW: Analysis of the mutational effects of the COP/DET/FUS loci on genome expression profiles reveals their overlapping yet not identical roles in regulating Arabidopsis seedling development. Development. 2003 Mar. PMID: 12538522

Zhao H, Pfeiffer R, Gail MH: Haplotype analysis in population genetics and association studies. Pharmacogenomics. 2003 Mar. PMID: 12605551

Tinetti ME: Clinical practice. Preventing falls in elderly persons. N Engl J Med. 2003 Jan 2. PMID: 12510042

Wang S, Kidd KK, Zhao H: On the use of DNA pooling to estimate haplotype frequencies. Genet Epidemiol. 2003 Jan. PMID: 12508258

Zhang S, Zhu X, Zhao H: On a semiparametric test to detect associations between quantitative traits and candidate genes using unrelated individuals. Genet Epidemiol. 2003 Jan. PMID: 12508255

Zou G, Zhao H: Haplotype frequency estimation in the presence of genotyping errors. Hum Hered. 2003. PMID: 14614247

Van Ness PH, Kasl SV, Jones BA: Religion, race, and breast cancer survival. Int J Psychiatry Med. 2003. PMID: 15152786

Gill TM, Kurland B: The burden and patterns of disability in activities of daily living among community-living older persons. J Gerontol A Biol Sci Med Sci. 2003 Jan. PMID: 12560415

Van Ness PH, Kasl SV: Religion and cognitive dysfunction in an elderly cohort. J Gerontol B Psychol Sci Soc Sci. 2003 Jan. PMID: 12496305

Wang H, Ma L, Habashi J, Li J, Zhao H, Deng XW: Analysis of far-red light-regulated genome expression profiles of phytochrome A pathway mutants in Arabidopsis. Plant J. 2002 Dec. PMID: 12472688

Mani A, Meraji SM, Houshyar R, Radhakrishnan J, Mani A, Ahangar M, Rezaie TM, Taghavinejad MA, Broumand B, Zhao H, Nelson-Williams C, Lifton RP: Finding genetic contributions to sporadic disease: a recessive locus at 12q24 commonly contributes to patent ductus arteriosus. Proc Natl Acad Sci U S A. 2002 Nov 12; 2002 Oct 30. PMID: 12409608

McGloin JM: Dying in Connecticut--the facts. Conn Med. 2002 Nov. PMID: 12476508

Hardy SE, Concato J, Gill TM: Stressful life events among community-living older persons. J Gen Intern Med. 2002 Nov. PMID: 12406354

Fried TR, Bradley EH, Towle VR: Assessment of patient preferences: integrating treatments and outcomes. J Gerontol B Psychol Sci Soc Sci. 2002 Nov. PMID: 12426443

Gill TM, Baker DI, Gottschalk M, Peduzzi PN, Allore H, Byers A: A program to prevent functional decline in physically frail, elderly persons who live at home. N Engl J Med. 2002 Oct 3. PMID: 12362007

Ma L, Gao Y, Qu L, Chen Z, Li J, Zhao H, Deng XW: Genomic evidence for COP1 as a repressor of light-regulated gene expression and development in Arabidopsis. Plant Cell. 2002 Oct. PMID: 12368493

Gill TM, Hardy SE, Williams CS: Underestimation of disability in community-living older persons. J Am Geriatr Soc. 2002 Sep. PMID: 12383145

Wu G, Tian X, Nishimura S, Markowitz GS, D'Agati V, Park JH, Yao L, Li L, Geng L, Zhao H, Edelmann W, Somlo S: Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease. Hum Mol Genet. 2002 Aug 1. PMID: 12140187

Van Ness PH, Larson DB: Religion, senescence, and mental health: the end of life is not the end of hope. Am J Geriatr Psychiatry. 2002 Jul-Aug. PMID: 12095898

Gill TM: Geriatric medicine: it's more than caring for old people. Am J Med. 2002 Jul. PMID: 12106630

Thomas KE, Hasbun R, Jekel J, Quagliarello VJ: The diagnostic accuracy of Kernig's sign, Brudzinski's sign, and nuchal rigidity in adults with suspected meningitis. Clin Infect Dis. 2002 Jul 1; 2002 Jun 5. PMID: 12060874

Fried TR, Bradley EH, Towle VR, Allore H: Understanding the treatment preferences of seriously ill patients. N Engl J Med. 2002 Apr 4. PMID: 11932474

Murphy SL, Williams CS, Gill TM: Characteristics associated with fear of falling and activity restriction in community-living older persons. J Am Geriatr Soc. 2002 Mar. PMID: 11943049

Vikram HR, Quagliarello VJ: Diagnosis and management of empyema. Curr Clin Top Infect Dis. 2002. PMID: 12520655

Zhang S, Zhao H: Linkage disequilibrium mapping with genotype data. Genet Epidemiol. 2002 Jan. PMID: 11754474

Erickson SE, Fried TR, Cherlin E, Johnson-Hurzeler R, Horwitz SM, Bradley EH: The effect of inpatient hospice units on hospice use post-admission. Home Health Care Serv Q. 2002. PMID: 12363002

Van Ness PH, Kasl SV, Jones BA: Are Religious Women More Likely to Have Breast Cancer Screening? J Relig Health. 2002 Winter. PMID: 23293394

Zhang S, Zhang K, Li J, Zhao H: On a family-based haplotype pattern mining method for linkage disequilibrium mapping. Pac Symp Biocomput. 2002. PMID: 11928467

Cheung KH, White K, Hager J, Gerstein M, Reinke V, Nelson K, Masiar P, Srivastava R, Li Y, Li J, Zhao H, Li J, Allison DB, Snyder M, Miller P, Williams K: YMD: a microarray database for large-scale gene expression analysis. Proc AMIA Symp. 2002. PMID: 12463803