Roman Ivasiy, MD, MPH
he/him/his
Associate Research ScientistCards
About
Research
Publications
2025
Integrating Methadone Services Into Primary Care in Ukraine: Two-Year Outcomes From a Randomized Trial.
Machavariani E, Esserman D, Dumchev K, Filippovych M, Pykalo I, Ivasiy R, Madden L, Bromberg D, Haddad M, Morozova O, Oliveros D, Ahmad B, Dvoriak S, Altice F. Integrating Methadone Services Into Primary Care in Ukraine: Two-Year Outcomes From a Randomized Trial. Annals Of Internal Medicine 2025 PMID: 41359964, DOI: 10.7326/annals-25-01764.Peer-Reviewed Original ResearchQuality health indicatorsHealth care usePrimary care settingPrimary careOpioid use disorderHealth indicatorsSpecialty clinicsCare useCare settingsOpioid agonist therapyTwo-group randomized controlled trialPrimary care centersSpecialty clinical careMiddle-income countriesRandomized Controlled TrialsProvider discomfortHealth outcomesHealth careComorbidity managementClinical careTwo-groupCareCare centerPrimary outcomeSpecialtyImplementation opportunities for optimizing retention on buprenorphine treatment for people with opioid use disorder in West Virginia
Ivasiy R, Madden L, Feinberg J, Christiansen M, Haas J, Johnson K, Machavariani E, Kwan B, Lane R, Kil N, Altice F. Implementation opportunities for optimizing retention on buprenorphine treatment for people with opioid use disorder in West Virginia. Drug And Alcohol Dependence 2025, 276: 112914. PMID: 41106293, DOI: 10.1016/j.drugalcdep.2025.112914.Peer-Reviewed Original ResearchOpioid use disorderBuprenorphine treatmentUse disorderBuprenorphine treatment of opioid use disorderHigher buprenorphine doseTreatment of opioid use disorderInitial dosageDays of medicationPrescription drug monitoring programsProportional hazards modelBuprenorphine doseTreatment discontinuationDrug monitoring programsOverdose-related deathsDiscontinuation riskHazard ratioPrimary outcomeReal-world practiceBuprenorphinePrescribing practicesHazards modelOpioid crisisProtective effectHigher dosageBaseline covariatesCombined response to commentaries regarding Ivasiy et al. (2025)
Ivasiy R, Madden L, Johnson K, Machavariani E, Ahmad B, Oliveros D, Tan J, Kil N, Altice F. Combined response to commentaries regarding Ivasiy et al. (2025). International Journal Of Drug Policy 2025, 145: 104935. PMID: 40752295, DOI: 10.1016/j.drugpo.2025.104935.Peer-Reviewed Original ResearchRetention and dropout from sublingual and extended-release buprenorphine treatment: A comparative analysis of data from a nationally representative sample of commercially-insured people with opiod use disorder in the United States
Ivasiy R, Madden L, Johnson K, Machavariani E, Ahmad B, Oliveros D, Tan J, Kil N, Altice F. Retention and dropout from sublingual and extended-release buprenorphine treatment: A comparative analysis of data from a nationally representative sample of commercially-insured people with opiod use disorder in the United States. International Journal Of Drug Policy 2025, 138: 104748. PMID: 40020306, PMCID: PMC12045481, DOI: 10.1016/j.drugpo.2025.104748.Peer-Reviewed Original ResearchConceptsOpioid use disorderSL-BUPXR-BUPUse disorderRetrospective cohort studyExtended-release buprenorphineReduce treatment discontinuationDays of supplyTreatment discontinuationSublingual buprenorphineReduce overdose riskBuprenorphine treatmentCohort studyHigh dosesPrimary outcomeImpact of dosagePatientsBuprenorphineMonthsMg/dayCommercially-insured individualsProportion of individualsOpioidOverdose riskImprove health outcomesExploration of the multi-level barriers to scaling up methadone for HIV prevention among people who inject drugs in Kazakhstan
Liberman A, Rozental Y, Ivasiy R, Kussainova A, Primbetova S, Madden L, Terlikbayeva A, Altice F. Exploration of the multi-level barriers to scaling up methadone for HIV prevention among people who inject drugs in Kazakhstan. Journal Of Substance Use And Addiction Treatment 2025, 172: 209640. PMID: 39986387, PMCID: PMC12009200, DOI: 10.1016/j.josat.2025.209640.Peer-Reviewed Original ResearchNominal group techniqueHIV preventionCommunity health workersMulti-level barriersIn-depth interviewsHealth workersPWID clientsSocioecological modelCommunity stakeholdersOpioid use disorderFocus groupsHIV epidemicClinical directorsClinical sitesEducating clientsOpioid agonist therapyImprove implementationGroup techniqueResearch teamCHWsPolicy levelUse disorderCliniciansAlternative medicationsEligibility
2024
Decrease in provider stigma is associated with improved quality health indicators among individuals receiving methadone in primary care centers in Ukraine
Machavariani E, Bromberg D, Dumchev K, Esserman D, Earnshaw V, Pykalo I, Filippovich M, Ivasiy R, Ahmad B, Long J, Haddad M, Madden L, Oliveros D, Dvoriak S, Altice F. Decrease in provider stigma is associated with improved quality health indicators among individuals receiving methadone in primary care centers in Ukraine. International Journal Of Drug Policy 2024, 136: 104682. PMID: 39705875, PMCID: PMC11821433, DOI: 10.1016/j.drugpo.2024.104682.Peer-Reviewed Original ResearchConceptsPrimary care centersQuality health indicatorsProvider stigmaEvidence-based practiceGuideline-concordantPatient outcomesHealth indicatorsReduce provider stigmaCare centerInfluence healthcare utilizationSpecialty health servicesPatient-level outcomesTele-educationImprove patient outcomesProvider fearsImplementation trialHealthcare utilizationPreventive careHealth servicesPoor healthLinear mixed-effects modelsImprove attitudesStigmaIncrease accessMixed-effects modelsDisruptions to HIV Prevention During Armed Conflict in Ukraine and Other Settings
Nikitin B, Bromberg D, Ivasiy R, Madden L, Machavariani E, Dvoriak S, Poole D, Otiashvilli D, Altice F. Disruptions to HIV Prevention During Armed Conflict in Ukraine and Other Settings. Current HIV/AIDS Reports 2024, 22: 10. PMID: 39672977, PMCID: PMC11823171, DOI: 10.1007/s11904-024-00716-x.Peer-Reviewed Original ResearchTransformation of the HIV treatment cascade for people who inject drugs in Ukraine
Bromberg D, Rhoades D, Madden L, Ivasiy R, Meteliuk A, Pykalo I, Filippovych M, Nikitin B, Farnum S, Fomenko T, Dvoriak S, Altice F. Transformation of the HIV treatment cascade for people who inject drugs in Ukraine. AIDS 2024, 39: 306-311. PMID: 39589135, DOI: 10.1097/qad.0000000000004056.Peer-Reviewed Original ResearchOpioid agonist therapyAntiretroviral therapyImprove HIV treatment outcomesHIV treatment outcomesHIV care cascadeCross-sectional biobehavioral surveyTreatment outcomesCare cascadeUkraine's HIV epidemicPrescription of antiretroviral therapyPrescribed antiretroviral therapyAdherence to antiretroviral therapyHIV treatment cascadeAgonist therapyBiobehavioral surveyOpioid dependenceHIV diagnosisTreatment cascadeHIV epidemicHIVOpioidPWIDTherapyDrugOutcomesTrajectory and progress of opioid agonist therapy programs in the Kyrgyz Republic
Liberman A, Kurmanalieva A, Biibosunova D, Shumskaya N, Ivasiy R, Bromberg D, Madden L, Altice F. Trajectory and progress of opioid agonist therapy programs in the Kyrgyz Republic. Global Health Economics And Sustainability 2024, 2: 2536. PMID: 40212662, PMCID: PMC11985161, DOI: 10.36922/ghes.2536.Peer-Reviewed Original ResearchOpioid agonist therapyHuman immunodeficiency virusMortality of human immunodeficiency virusOpioid agonist therapy programsOpioid use disorderMethadone programsHIV prevention strategiesAgonist therapyImmunodeficiency virusClinical protocolsEffective treatmentUse disorderNeighboring countriesHIV preventionKyrgyz RepublicMethadoneOpioidCentral AsiaIncreased state supportCentral Asian countriesDrugCarceral systemInternational donorsLocal news coveragePolitical challengesDesign and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine
Machavariani E, Dumchev K, Pykalo I, Filippovych M, Ivasiy R, Esserman D, Madden L, Bromberg D, Haddad M, Morozova O, Ahmad B, Gómez D, Farnum S, Dvoriak S, Altice F. Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine. Contemporary Clinical Trials 2024, 146: 107690. PMID: 39265780, PMCID: PMC11531372, DOI: 10.1016/j.cct.2024.107690.Peer-Reviewed Original ResearchPrimary care centersQuality health indicatorsNon-communicable diseasesSpecialty treatment centersOpioid agonist therapyImplementation of integrated carePay-for-performance incentivesPrimary care clinicsPrimary care settingSelf-reported prevalencePay-for-performancePrevalence of medical comorbiditiesParticipants self-reportedEffective evidence-based treatmentsHealth of PWIDEvidence-based treatmentsIntegrated careCare clinicsImplementation outcomesImplementation trialCare settingsElectronic chart reviewHigh-burden countriesSpecialty servicesHIV prevalence