2023
ACLP Best Practice Guidance: Evaluation and Treatment of Depression in Solid Organ Transplant Recipients
Zimbrean P, Andrews S, Hussain F, Fireman M, Kuntz K, Niazi S, Simpson S, Soeprono T, Winder G, Jowsey-Gregoire S. ACLP Best Practice Guidance: Evaluation and Treatment of Depression in Solid Organ Transplant Recipients. Journal Of The Academy Of Consultation-Liaison Psychiatry 2023, 64: 357-370. PMID: 37003570, DOI: 10.1016/j.jaclp.2023.03.007.Peer-Reviewed Original ResearchConceptsOrgan transplant recipientsSolid organ transplant recipientsTransplant recipientsDepressive disorderFirst-line antidepressantsTreatment of depressionMental health carePosttransplant depressionSOT recipientsTransplant patientsTreating providerClinical evaluationPositive screeningTreatment interventionsPatientsRecipientsHealth careDepressionDisordersConsensus processFrequent problemSpecial Interest GroupTreatmentPractice guidanceBest practice guidance
2022
Major Depressive Disorder in an International Multisite Wilson Disease Registry
Camarata M, Ala A, Coskun A, Deng Y, Embel V, Gonzalez-Peralta R, Maciejewski K, Patel A, Rubman S, To U, Tomlin R, Schilsky M, Zimbrean P. Major Depressive Disorder in an International Multisite Wilson Disease Registry. Journal Of The Academy Of Consultation-Liaison Psychiatry 2022, 64: 106-117. PMID: 36521682, DOI: 10.1016/j.jaclp.2022.12.001.Peer-Reviewed Original ResearchConceptsMajor depressive disorderWilson's diseaseDepressive disorderLifetime major depressive disorderMental health QOLPhysical health QoLMajor depressive episodeMental health qualityStructured psychiatric evaluationSignificant differencesCross-sectional reportsLiver testsLiver diseaseNeurological assessmentLife scoresClinical correlatesDepressive episodePsychiatric symptomsPsychiatric evaluationDisease RegistrySevere anxietyLaboratory testsLifetime historySignificant associationPatientsA multidisciplinary approach to the diagnosis and management of Wilson disease: Executive summary of the 2022 Practice Guidance on Wilson disease from the American Association for the Study of Liver Diseases
Schilsky ML, Roberts EA, Bronstein JM, Dhawan A, Hamilton JP, Rivard AM, Washington MK, Weiss KH, Zimbrean PC. A multidisciplinary approach to the diagnosis and management of Wilson disease: Executive summary of the 2022 Practice Guidance on Wilson disease from the American Association for the Study of Liver Diseases. Hepatology 2022, 77: 1428-1455. PMID: 36152019, DOI: 10.1002/hep.32805.Peer-Reviewed Original ResearchDepression in transplantation
Zimbrean PC. Depression in transplantation. Current Opinion In Organ Transplantation 2022, 27: 535-545. PMID: 36227755, DOI: 10.1097/mot.0000000000001024.Peer-Reviewed Original ResearchConceptsRisk factorsTransplant recipientsTransplant populationHigher healthcare utilizationOrgan transplant recipientsImprovement of depressionImpact of depressionEffective treatment interventionsRates of depressionSocial risk factorsCognitive behavioral therapyKidney recipientsPosttransplant depressionTransplantation candidatesHealthcare utilizationSupportive therapyClinical statusCommon findingDepression correlatesGeneral populationOrgan donorsTreatment interventionsBehavioral therapyRecipientsDepressionCannabinoids and solid organ transplantation: Psychiatric perspectives and recommendations
Winder GS, Andrews SR, Banerjee AG, Hussain F, Ivkovic A, Kuntz K, Omary L, Shenoy A, Thant T, VandenBerg A, Zimbrean P. Cannabinoids and solid organ transplantation: Psychiatric perspectives and recommendations. Transplantation Reviews 2022, 36: 100715. PMID: 35853383, DOI: 10.1016/j.trre.2022.100715.Peer-Reviewed Original ResearchConceptsSolid organ transplantationCannabinoid useOrgan transplantationClinical careUS transplantation centersSOT patientsKidney transplantationTransplantation centersCannabinoid effectsClinical impactClinicians' perceptionsMedical literaturePatientsTransplantationCliniciansCannabinoidsCareInterprofessional issuesPsychiatric perspectiveFuture studiesUse ratesProfessional societiesSystematized reviewOngoing dilemmaRecommendationsSubstance use screening in transplant populations: Recommendations from a consensus workgroup
Jowsey-Gregoire S, Jannetto PJ, Jesse MT, Fleming J, Winder GS, Balliet W, Kuntz K, Vasquez A, Weinland S, Hussain F, Weinrieb R, Fireman M, Nickels MW, Peipert JD, Thomas C, Zimbrean PC. Substance use screening in transplant populations: Recommendations from a consensus workgroup. Transplantation Reviews 2022, 36: 100694. PMID: 35537285, DOI: 10.1016/j.trre.2022.100694.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersTransplant patientsDrug testingConsultation-liaison psychiatryTransplant populationTransplant teamClinical historyOptimal carePatient practicesPatientsCurrent laboratory testingAmerican SocietyDisordersTransplantationPharmacy communityPossible risksInsurance issuesLaboratory testingOngoing testingRiskCertain substancesGroup discussionsTestingSubstancesPreoperative Management of Medications for Psychiatric Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement
Oprea AD, Keshock MC, O'Glasser AY, Cummings KC, Edwards AF, Zimbrean PC, Urman RD, Mauck KF. Preoperative Management of Medications for Psychiatric Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement. Mayo Clinic Proceedings 2022, 97: 397-416. PMID: 35120702, DOI: 10.1016/j.mayocp.2021.11.011.Peer-Reviewed Original ResearchConceptsPsychiatric medication managementPreoperative managementPerioperative assessmentMedication managementConsensus statementQuality Improvement (SPAQI) Consensus StatementAttention deficit hyperactivity disorder medicationsDay of surgeryRisk of relapseHyperactivity disorder medicationsCategories of drugsMedication classesPerioperative complicationsDiseases SocietyMost medicationsIndividual medicationsMood stabilizersPsychiatric medicationsConsensus recommendationsMedicationsDrug categoriesCertain drugsPatient carePsychiatric conditionsProcedure cancellations
2021
Management of Substance Use Disorders in a Patient With Left Ventricular Assist Device
Choi J, Alexis J, Gosev I, Zimbrean P, Nickels M. Management of Substance Use Disorders in a Patient With Left Ventricular Assist Device. Journal Of The Academy Of Consultation-Liaison Psychiatry 2021, 62: 568-576. PMID: 34391977, DOI: 10.1016/j.jaclp.2021.07.015.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersVentricular assist deviceHeart failureAssist deviceAdvanced heart failureChallenging patient populationHeart failure managementRole of LVADsLVAD candidatesConsultation-liaison psychiatryCardiac surgeryPatient populationPatient outcomesClinical casesPatientsFailure managementDisordersLVADAvailable literatureTreatmentLimited literatureSurgeryFailureManagementIdentifying the Most Important Consultation-Liaison Psychiatry Publications in 2020 Using a Novel Literature Assessment Instrument
Simpson SA, Bienvenu OJ, Andrews SR, Close JS, Adler Cohen MA, Fernandez-Robles C, Francis BA, Gandhi J, Gangopadhyay M, Gershengoren L, Grimaldi JA, Isenberg-Grzeda E, Key RG, Kiong T, Kontos N, Loh RM, Luchsinger W, Munjal S, Niazi SK, Nichols NA, Pathare A, Pereira LF, Shim JJ, Tobin MB, Zimbrean PC. Identifying the Most Important Consultation-Liaison Psychiatry Publications in 2020 Using a Novel Literature Assessment Instrument. Journal Of The Academy Of Consultation-Liaison Psychiatry 2021, 62: 493-500. PMID: 34048960, DOI: 10.1016/j.jaclp.2021.03.006.Peer-Reviewed Original ResearchConceptsConsultation-liaison psychiatryEvidence-based careSevere mental illnessConsultation-liaison psychiatristsExcellent interrater reliabilityComplex patientsEvidence-based practiceLithium treatmentAssessment instrumentsClinical practiceClinical importanceMedical riskMental illnessMedical settingsPractice areaQuality InstrumentArticles of interestInterrater reliabilityStandardized assessmentCOVID-19PatientsAggregate scoreLiterature reviewGuidelinesPsychiatryThe Effect of Mental Health, Neurological Disease, and Liver Disease on Quality of Life in Patients With Wilson Disease
Camarata MA, Ala A, Coskun AK, Deng Y, Gonzalez-Peralta R, Maciejewski KR, Patel A, Rubman S, To U, Tomlin R, Schilsky ML, Zimbrean PC. The Effect of Mental Health, Neurological Disease, and Liver Disease on Quality of Life in Patients With Wilson Disease. Journal Of The Academy Of Consultation-Liaison Psychiatry 2021, 62: 528-537. PMID: 34044196, PMCID: PMC11165927, DOI: 10.1016/j.jaclp.2021.04.004.Peer-Reviewed Original ResearchConceptsRating Scale scoresP-QOL scoresP-QOLNeurological diseasesWilson's diseaseMental healthOverall QoLUnified Wilson's Disease Rating Scale scoreScale scoreEnd-stage liver disease (MELD) scoreDisease severityStage liver disease scoreDegree of liverNeurological disease severityLiver Disease scoreLiver disease severityMajor depressive disorderQuality of lifeMental health issuesChild-PughCirrhosis severityLiver diseaseNeurological assessmentPatients' qualityChronic disorders
2020
Substance Use Disorder Detection Rates Among Providers of General Medical Inpatients
Serowik KL, Yonkers KA, Gilstad-Hayden K, Forray A, Zimbrean P, Martino S. Substance Use Disorder Detection Rates Among Providers of General Medical Inpatients. Journal Of General Internal Medicine 2020, 36: 668-675. PMID: 33111239, PMCID: PMC7947066, DOI: 10.1007/s11606-020-06319-7.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersMedical inpatientsPatient characteristicsMedical recordsGeneral medical inpatient unitsPatient self-report questionnairesGeneral medical inpatientsMedical inpatient unitsOpioid use disorderDrug use disordersNicotine use disorderPatients' medical recordsCannabis use disorderLarge teaching hospitalAlcohol use disorderDetection rateCocaine use disorderWhite patientsBlack patientsFemale patientsHispanic patientsFormal screeningInpatient providersTeaching hospitalCost and cost-effectiveness of three strategies for implementing motivational interviewing for substance misuse on medical inpatient units
Olmstead TA, Yonkers KA, Forray A, Zimbrean P, Gilstad-Hayden K, Martino S. Cost and cost-effectiveness of three strategies for implementing motivational interviewing for substance misuse on medical inpatient units. Drug And Alcohol Dependence 2020, 214: 108156. PMID: 32659637, PMCID: PMC7448551, DOI: 10.1016/j.drugalcdep.2020.108156.Peer-Reviewed Original ResearchThe Educational Value of Outpatient Consultation-Liaison Rotations: A White Paper From the Academy of Consultation-Liaison Psychiatry Residency Education Subcommittee
Zimbrean PC, Ernst CL, Forray A, Beach SR, Lavakumar M, Siegel AM, Soeprono T, Schwartz AC. The Educational Value of Outpatient Consultation-Liaison Rotations: A White Paper From the Academy of Consultation-Liaison Psychiatry Residency Education Subcommittee. Journal Of The Academy Of Consultation-Liaison Psychiatry 2020, 61: 436-449. PMID: 32650995, PMCID: PMC7235569, DOI: 10.1016/j.psym.2020.05.004.Peer-Reviewed Original ResearchSystematic Review: Treatment for Addictive Disorder in Transplant Patients
Luchsinger W, Zimbrean P. Systematic Review: Treatment for Addictive Disorder in Transplant Patients. American Journal On Addictions 2020, 29: 445-462. PMID: 32410396, DOI: 10.1111/ajad.13054.Peer-Reviewed Original ResearchConceptsTransplant patientsAlcohol use disorderUse disordersOrgan transplantationAddictive disordersSystematic reviewLiver transplant patientsOpioid use disorderNumber of patientsPromising treatment optionSubstance use disordersOpioid disordersFirst systematic reviewTransplant candidatesHeart transplantTreatment optionsCase reportOutcome measuresMedical statusHigh riskPatientsDatabases PubMedTreatment interventionsControl groupLiterature searchUpdates in Consultation-Liaison Psychiatry: 2019
Simpson SA, Chwastiak LA, Andrews SR, Bienvenu OJ, Adler Cohen M, Cozza KL, DiMartini A, Fernandez-Robles C, Grimaldi J, Isenberg-Grzeda E, King Iv F, Kontos N, Luchsinger W, Munjal S, Pathare A, Pereira LF, Philbrick K, Rosen JH, Schmelzer NA, Zimbrean PC. Updates in Consultation-Liaison Psychiatry: 2019. Journal Of The Academy Of Consultation-Liaison Psychiatry 2020, 61: 450-455. PMID: 32665149, DOI: 10.1016/j.psym.2020.05.001.Peer-Reviewed Original ResearchConceptsConsultation-liaison psychiatryCurrent evidence-based practiceCutting-edge careSubstance use disordersConsultation-liaison psychiatristsClinical findingsEvidence-based practiceConsultation psychiatristsUse disordersClinical practiceBusy cliniciansPractice areaCliniciansCurrent literatureCareImportant manuscriptsArticle reviewsPsychiatristsAggregate scorePsychiatryHighest aggregate score
2019
Online Curriculum in Transplant Psychiatry
Zimbrean PC. Online Curriculum in Transplant Psychiatry. Journal Of The Academy Of Consultation-Liaison Psychiatry 2019, 61: 254-260. PMID: 32007306, DOI: 10.1016/j.psym.2019.12.006.Peer-Reviewed Original ResearchImplementing Motivational Interviewing for Substance Misuse on Medical Inpatient Units: a Randomized Controlled Trial
Martino S, Zimbrean P, Forray A, Kaufman JS, Desan PH, Olmstead TA, Gilstad-Hayden K, Gueorguieva R, Yonkers KA. Implementing Motivational Interviewing for Substance Misuse on Medical Inpatient Units: a Randomized Controlled Trial. Journal Of General Internal Medicine 2019, 34: 2520-2529. PMID: 31468342, PMCID: PMC6848470, DOI: 10.1007/s11606-019-05257-3.Peer-Reviewed Original ResearchConceptsConsultation-liaison serviceSubstance misuseMotivational interviewMedical inpatientsGeneral medical inpatient servicesMedical inpatient servicesGeneral medical inpatientsStudy-eligible patientsMedical inpatient unitsAcute care hospitalsMain MeasuresPrimary outcomesMedical education workshopSecondary outcomesCare hospitalControlled TrialsEffective implementation strategiesMeasuresPrimary outcomesMedical HospitalInpatient unitInpatient servicesMedical ordersPatientsPatients' statementsMotivational interviewingInpatientsBody Image in Liver Transplantation Recipients
Zimbrean PC, Gan G, Deng Y, Emre S. Body Image in Liver Transplantation Recipients. Liver Transplantation 2019, 25: 712-723. PMID: 30746848, DOI: 10.1002/lt.25432.Peer-Reviewed Original ResearchConceptsLiver transplant recipientsTransplant recipientsQuality of lifeBI concernsLiver transplantation recipientsChronic liver diseaseAcute liver failureCross-sectional studyMental health carePaucity of dataLiver transplantationTransplantation recipientsYounger patientsLiver failureLiver diseaseQOL scoresOrgan transplantationPatientsRecipientsHealth careBody image concernsTransplantationLow incomeBody imageDepression
2018
The 2018 ISHLT/APM/AST/ICCAC/STSW recommendations for the psychosocial evaluation of adult cardiothoracic transplant candidates and candidates for long-term mechanical circulatory support
Dew MA, DiMartini AF, Dobbels F, Grady KL, Jowsey-Gregoire SG, Kaan A, Kendall K, Young QR, Abbey SE, Butt Z, Crone CC, De Geest S, Doligalski CT, Kugler C, McDonald L, Ohler L, Painter L, Petty MG, Robson D, Schlöglhofer T, Schneekloth TD, Singer JP, Smith PJ, Spaderna H, Teuteberg JJ, Yusen RD, Zimbrean PC. The 2018 ISHLT/APM/AST/ICCAC/STSW recommendations for the psychosocial evaluation of adult cardiothoracic transplant candidates and candidates for long-term mechanical circulatory support. The Journal Of Heart And Lung Transplantation 2018, 37: 803-823. PMID: 29709440, DOI: 10.1016/j.healun.2018.03.005.Peer-Reviewed Original ResearchConceptsMechanical circulatory supportLong-term mechanical circulatory supportPsychosocial evaluationLung transplantationCirculatory supportTransplant social workersConsensus-based setISHLT guidelinesMCS implantationHeart transplantationTransplant candidatesUnique needsPatient receiptCardiothoracic transplantationConsensus statementWriting committeeTransplantationPsychosocial domainsAssists cliniciansSelection of candidatesHealth CouncilISHLTAmerican SocietyPsychosomatic medicineInternational SocietyText Messaging to Reduce Alcohol Relapse in Prelisting Liver Transplant Candidates: A Pilot Feasibility Study
DeMartini KS, Schilsky ML, Palmer A, Fehon DC, Zimbrean P, O'Malley SS, Lee HB, Toll BA. Text Messaging to Reduce Alcohol Relapse in Prelisting Liver Transplant Candidates: A Pilot Feasibility Study. Alcohol Clinical And Experimental Research 2018, 42: 761-769. PMID: 29498753, PMCID: PMC6438371, DOI: 10.1111/acer.13603.Peer-Reviewed Original ResearchConceptsAlcoholic liver diseaseLiver transplant candidatesLiver transplant patientsStandard careEfficacy outcomesTransplant patientsTransplant candidatesFeasibility outcomesTM participantsAlcohol interventionsClinical efficacy outcomesLiver transplantation programPreliminary efficacy outcomesPrimary feasibility outcomePilot feasibility trialPilot feasibility studyRelapse prevention interventionsBetter treatment outcomesLiver diseaseFeasibility trialUnited NetworkTransplantation programIntervention satisfactionTreatment outcomesAlcohol relapse