2008
Impairment of Working Memory Maintenance and Response in Schizophrenia: Functional Magnetic Resonance Imaging Evidence
Driesen NR, Leung HC, Calhoun VD, Constable RT, Gueorguieva R, Hoffman R, Skudlarski P, Goldman-Rakic PS, Krystal JH. Impairment of Working Memory Maintenance and Response in Schizophrenia: Functional Magnetic Resonance Imaging Evidence. Biological Psychiatry 2008, 64: 1026-1034. PMID: 18823880, PMCID: PMC2650279, DOI: 10.1016/j.biopsych.2008.07.029.Peer-Reviewed Original ResearchConceptsMemory taskPrefrontal activityMemory maintenanceBrain activationFunctional Magnetic Resonance Imaging EvidenceWorking Memory MaintenanceCognitive impairmentHealthy comparison participantsPrefrontal cortical activityFunctional magnetic resonanceMemory loadComparison participantsTask accuracyDistinct neurobiologyCortical activityHealthy participantsBasic research insightsImaging EvidenceMemoryCortical deficitsCortical functionPoor performanceTaskSchizophreniaResponse phase
2006
Hypoglycemia reduces the blood‐oxygenation level dependent signal in primary auditory and visual cortex: A functional magnetic resonance imaging study
Driesen NR, Goldberg PA, Anderson AW, Tang L, Flanagan DE, Sherwin RS, Gore JC. Hypoglycemia reduces the blood‐oxygenation level dependent signal in primary auditory and visual cortex: A functional magnetic resonance imaging study. Journal Of Neuroscience Research 2006, 85: 575-582. PMID: 17154420, DOI: 10.1002/jnr.21146.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingFunctional magnetic resonance imagingModerate hypoglycemiaVisual cortexResonance imagingCentral nervous system effectsMagnetic resonance imaging studyNon-diabetic controlsNon-diabetic participantsNervous system effectsBlood oxygenation level-dependent (BOLD) signalFrequent hypoglycemic episodesBlood oxygenation level-dependent (BOLD) responseEffects of hypoglycemiaResonance imaging studyFunctional magnetic resonance imaging studyLevel-dependent signalLevel-dependent responsesVisual stimuliHypoglycemic episodesT1DM patientsPrimary auditoryEuglycemic periodHypoglycemic responseNeurophysiologic changes