2024
Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes
Son M, Riley L, Staniczenko A, Cron J, Yen S, Thomas C, Sholle E, Osborne L, Lipkind H. Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes. JAMA Network Open 2024, 7: e2419268. PMID: 38976271, PMCID: PMC11231799, DOI: 10.1001/jamanetworkopen.2024.19268.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusNeonatal intensive care unitPreterm birthWeeks gestationRisk of HDPPerinatal outcomesLogistic regression modelsIncreased riskPregnant individualsPrenatal vaccinationSmall-for-gestational age birth weightNeonatal intensive care unit admissionCohort studyIncreased risk of PTBOdds ratioIncreased risk of HDPRisk of preterm birthRespiratory syncytial virus seasonRespiratory syncytial virus vaccineRetrospective observational cohort studyNeonatal respiratory distressVaccination statusMultivariate logistic regression modelObservational cohort studyCox regression models
2023
Low-Dose Aspirin during Pregnancy and Postpartum Bleeding
White K, Son M, Lundsberg L, Culhane J, Partridge C, Reddy U, Merriam A. Low-Dose Aspirin during Pregnancy and Postpartum Bleeding. American Journal Of Perinatology 2023, 40: 1390-1397. PMID: 37211010, DOI: 10.1055/a-2096-5199.Peer-Reviewed Original ResearchConceptsLow-dose aspirinPostpartum blood lossTiming of discontinuationBlood lossPostpartum bleedingPostpartum hemorrhageLDA useUse of LDARed blood cell transfusionBlood cell transfusionRetrospective cohort studySystemic lupus erythematosusTime of deliveryDiagnosis of diabetesLogistic regression modelingElectronic medical recordsAspirin 81Ideal dosingPreeclampsia preventionCell transfusionDose aspirinCohort studyHypertensive diseaseLupus erythematosusPrimary outcome
2022
Postpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic
Handley SC, Gallagher K, Lindgren E, Lo JY, Burris HH, Dysart KC, Greenspan J, Culhane JF, Son M. Postpartum Length of Stay and Hospital Readmission Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic. Obstetrics And Gynecology 2022, 139: 381-390. PMID: 35115443, DOI: 10.1097/aog.0000000000004687.Peer-Reviewed Original ResearchConceptsCoronavirus disease 2019 (COVID-19) pandemicObstetric patientsHospital readmissionMode of deliveryPostpartum hospitalizationDisease 2019 pandemicHospitalization dischargeCOVID-19 pandemicRetrospective cohort studyWeeks of gestationDays of deliveryLogistic mixed-effects modelsCohort studyHospitalization lengthSecondary outcomesPrimary outcomeAdjusted analysisStudy cohortVaginal birthCesarean birthReadmissionPostpartum lengthPatientsHospitalizationMixed-effects models
2021
Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy Outcomes in a U.S. Population
Son M, Gallagher K, Lo JY, Lindgren E, Burris HH, Dysart K, Greenspan J, Culhane JF, Handley SC. Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy Outcomes in a U.S. Population. Obstetrics And Gynecology 2021, 138: 542-551. PMID: 34433180, PMCID: PMC8454282, DOI: 10.1097/aog.0000000000004547.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionAdverse pregnancy-related outcomesPregnancy-related outcomesCoronavirus disease 2019 (COVID-19) pandemicDisease 2019 pandemicPregnancy outcomesGestational ageSARS-CoV-2 testingDiverse U.S. cohortAdverse pregnancy outcomesRetrospective cohort studyPositive test resultsSARS-CoV-2 diagnosisSignificant differencesNegative test resultsHypertensive disordersPlacental abruptionBaseline characteristicsCohort studyPreterm birthPostpartum hemorrhagePregnant womenCesarean birthU.S. cohortPublic insuranceA Multivariable Predictive Model for Success of External Cephalic Version
Dahl CM, Zhang Y, Ong JX, Yeh C, Son M, Miller ES, Roy A, Grobman WA. A Multivariable Predictive Model for Success of External Cephalic Version. Obstetrics And Gynecology 2021, 138: 426-433. PMID: 34352823, DOI: 10.1097/aog.0000000000004518.Peer-Reviewed Original ResearchConceptsBody mass indexFetal malpresentationPlacental locationECV successECV attemptPatient characteristicsFetal weightMaternal ageSingle quaternary care hospitalMultivariable logistic regression modelExternal cephalic versionExternal cephalic version successQuaternary care hospitalMultivariable predictive modelAmniotic fluid volumeYears of ageLogistic regression modelsObjective patient characteristicsHigh discriminatory capacitySingleton gestationsCare hospitalGestational agePatient factorsMass indexCephalic versionPatient characteristics associated with complications of external cephalic version
Dahl CM, Zhang Y, Ong JX, Yeh C, Son M, Miller ES, Roy A, Grobman WA. Patient characteristics associated with complications of external cephalic version. American Journal Of Obstetrics & Gynecology MFM 2021, 3: 100411. PMID: 34058425, DOI: 10.1016/j.ajogmf.2021.100411.Peer-Reviewed Original ResearchConceptsExternal cephalic versionBody mass indexPatient characteristicsCephalic versionPlacental locationGestational ageFetal weightMass indexCord prolapsePlacental abruptionFetal statusSpontaneous ruptureIntensive care unit admissionSingle quaternary care centerHigher body mass indexExternal cephalic version attemptAnterior placental locationNonreassuring fetal statusUmbilical cord prolapseCare unit admissionCord arterial pHGreater gestational ageMultivariable logistic regressionQuaternary care centerExternal cephalic version successFactors associated with appropriate treatment of acute-onset severe obstetrical hypertension
Deshmukh US, Lundsberg LS, Culhane JF, Partridge C, Reddy UM, Merriam AA, Son M. Factors associated with appropriate treatment of acute-onset severe obstetrical hypertension. American Journal Of Obstetrics And Gynecology 2021, 225: 329.e1-329.e10. PMID: 34023314, DOI: 10.1016/j.ajog.2021.05.012.Peer-Reviewed Original ResearchConceptsBlood pressure measurementsElevated blood pressure measurementsFirst-line antihypertensive agentsFirst-line agentsDelivery hospitalizationsHypertension emergencyAntihypertensive treatmentHypertensive emergenciesSevere hypertensionAntihypertensive agentsAmerican CollegeFirst-line antihypertensive therapyFirst-line antihypertensive treatmentMultivariable logistic regression modelGuideline-concordant treatmentPersistent severe hypertensionGuideline-concordant careClinical risk factorsHospital electronic medical recordsHypertension management guidelinesWeeks of gestationCase-control studyElectronic medical recordsLogistic regression modelsPressure measurementsHigh-Dose Compared With Standard-Dose Oxytocin Regimens to Augment Labor in Nulliparous Women
Son M, Roy A, Stetson BT, Grady NT, Vanecko MC, Bond N, Swanson K, Grobman WA, Miller ES, Peaceman AM. High-Dose Compared With Standard-Dose Oxytocin Regimens to Augment Labor in Nulliparous Women. Obstetrics And Gynecology 2021, 137: 991-998. PMID: 33957657, DOI: 10.1097/aog.0000000000004399.Peer-Reviewed Original ResearchConceptsHigh-dose groupHigh-dose oxytocin regimenStandard dosingAugmentation of laborUmbilical artery acidemiaLabor durationPrimary outcomeSecondary outcomesNulliparous womenCesarean birthNeonatal intensive care unit admissionIntensive care unit admissionApgar score 3Care unit admissionStandard-dose groupPrespecified secondary outcomesPrimary cesarean birthWeeks of gestationAugment laborClinical chorioamnionitisMorbidity compositeNulliparous participantsUnit admissionObstetric morbidityPerinatal outcomes
2020
Association Between Time of Day and the Decision for an Intrapartum Cesarean Delivery.
Son M, Lai Y, Bailit J, Reddy UM, Wapner RJ, Varner MW, Thorp JM, Caritis SN, Prasad M, Tita ATN, Saade G, Sorokin Y, Rouse DJ, Blackwell SC, Tolosa JE. Association Between Time of Day and the Decision for an Intrapartum Cesarean Delivery. Obstetrics And Gynecology 2020, 135: 535-541. PMID: 32028489, PMCID: PMC7595762, DOI: 10.1097/aog.0000000000003707.Peer-Reviewed Original ResearchConceptsIntrapartum cesarean deliveryCesarean deliveryMedian durationNulliparous womenMulticenter observational cohortOverall cesarean deliveryCesarean delivery rateLive gestationEligible womenObservational cohortSecondary outcomesPrimary outcomeVertex presentationMedian timeFetal statusKruskal-Wallis testHome birthTime of daySecondary analysisComplete dilationBivariate analysisContinuous outcomesDystociaWomenNonlinear association
2018
Maternal Obstetric Complication Rates Remain High in Illinois: A Retrospective Study, 2010–2015
Roy A, Peaceman A, Son M, Feinglass J. Maternal Obstetric Complication Rates Remain High in Illinois: A Retrospective Study, 2010–2015. The Joint Commission Journal On Quality And Patient Safety 2018, 45: 24-30. PMID: 30121161, DOI: 10.1016/j.jcjq.2018.02.007.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityMaternal morbidityMaternal complicationsCesarean deliveryDelivery complicationsComplication rateSevere maternal morbidity ratesStudy periodMaternal complication ratesMaternal morbidity ratesMaternal obstetric complicationsObstetric complication ratesObstetrics residency programsRetrospective cohort studyNinth Revision codesObstetric complicationsClinical characteristicsCohort studyPatient characteristicsChildbirth outcomesMorbidity ratePreventable complicationsRevision codesIllinois HospitalMorbidityAssociation Between Attempted External Cephalic Version and Perinatal Morbidity and Mortality
Son M, Roy A, Grobman WA, Miller ES. Association Between Attempted External Cephalic Version and Perinatal Morbidity and Mortality. Obstetrics And Gynecology 2018, 132: 365-370. PMID: 29995733, PMCID: PMC6060011, DOI: 10.1097/aog.0000000000002699.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unit admissionIntensive care unit admissionComposite perinatal morbidityCare unit admissionPerinatal morbidityECV attemptWeeks of gestationUnit admissionMortality outcomesNeonatal anemiaLower mean body mass indexMean body mass indexExternal cephalic version attemptNeonatal therapeutic hypothermiaNonanomalous singleton gestationsRetrospective cohort studyTertiary care institutionBody mass indexExternal cephalic versionNonvertex presentationExpectant managementCohort studyFetal malpresentationSecondary outcomesSingleton gestations
2017
Attempted operative vaginal delivery vs repeat cesarean in the second stage among women undergoing a trial of labor after cesarean delivery
Son M, Roy A, Grobman WA. Attempted operative vaginal delivery vs repeat cesarean in the second stage among women undergoing a trial of labor after cesarean delivery. American Journal Of Obstetrics And Gynecology 2017, 216: 407.e1-407.e5. PMID: 28153660, DOI: 10.1016/j.ajog.2017.01.013.Peer-Reviewed Original ResearchConceptsTrial of laborOperative vaginal deliveryRepeat cesarean deliveryVaginal delivery attemptFrequency of endometritisCesarean deliveryVaginal deliverySecond-stage laborNeonatal outcomesFetal stationHuman Development Maternal-Fetal Medicine Units NetworkMaternal-Fetal Medicine Units NetworkLower mean body mass indexMean body mass indexEunice Kennedy Shriver National InstituteNon-Hispanic black raceNeonatal adverse outcomesPrevious vaginal deliverySpontaneous vaginal deliveryBody mass indexRetrospective secondary analysisCesarean RegistryNeonatal complicationsNonanomalous gestationsCephalic presentation
2016
The association between intrauterine balloon tamponade duration and postpartum hemorrhage outcomes
Einerson BD, Son M, Schneider P, Fields I, Miller ES. The association between intrauterine balloon tamponade duration and postpartum hemorrhage outcomes. American Journal Of Obstetrics And Gynecology 2016, 216: 300.e1-300.e5. PMID: 27823918, DOI: 10.1016/j.ajog.2016.10.040.Peer-Reviewed Original ResearchConceptsIntrauterine balloon tamponadeIntensive care unit admissionCare unit admissionBlood product transfusionBalloon tamponadePostpartum feverPostpartum hemorrhageTamponade durationUnit admissionHospital lengthProduct transfusionBlood lossClinical outcomesMaternal intensive care unit admissionPacked red blood cellsMultivariable logistic regression modelHemorrhage-related outcomesMean hospital lengthRetrospective cohort studyFirst-line treatmentUterine artery embolizationLength of stayLack of associationLogistic regression modelsArtery embolizationAssociation among Maternal Obesity, Cervical Length, and Preterm Birth
Palatnik A, Miller ES, Son M, Kominiarek MA. Association among Maternal Obesity, Cervical Length, and Preterm Birth. American Journal Of Perinatology 2016, 34: 471-479. PMID: 27704492, PMCID: PMC7189342, DOI: 10.1055/s-0036-1593350.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthBody mass indexMid-trimester cervical lengthCervical lengthHigh BMI groupBMI groupsPreterm birthMaternal body mass indexPrior spontaneous preterm birthHigher body mass indexLong cervical lengthCervical length assessmentPotential protective effectMaternal obesityRetrospective cohortSingleton pregnanciesMass indexMultivariable analysisUnivariable analysisDecreased riskProtective effectMultivariable regressionGroup 2Length assessmentWeeksIs There an Association Between Indication for Intrauterine Balloon Tamponade and Balloon Failure?
Son M, Einerson BD, Schneider P, Fields IC, Grobman WA, Miller ES. Is There an Association Between Indication for Intrauterine Balloon Tamponade and Balloon Failure? American Journal Of Perinatology 2016, 34: 164-168. PMID: 27367285, DOI: 10.1055/s-0036-1585084.Peer-Reviewed Original ResearchConceptsIntrauterine balloon tamponadeFresh frozen plasmaUterine atonyPostpartum hemorrhageBalloon tamponadeRed blood cellsBalloon placementIntensive care unit admissionCare unit admissionUterine artery embolizationUnit admissionICU admissionSite bleedingArtery embolizationCohort studySecondary outcomesBlood lossPrimary outcomeRBC transfusionPotential confoundersFrozen plasmaMedian EBLBleedingTransfusionAtonyIs mode of delivery associated with the risk of necrotizing enterocolitis?
Son M, Grobman WA, Miller ES. Is mode of delivery associated with the risk of necrotizing enterocolitis? American Journal Of Obstetrics And Gynecology 2016, 215: 389.e1-389.e4. PMID: 27173084, DOI: 10.1016/j.ajog.2016.04.058.Peer-Reviewed Original ResearchConceptsMode of deliveryCesarean deliveryGestational agePreterm deliveryVaginal deliveryBivariable analysisPotential confoundersExtreme preterm deliveryMother-neonate pairsNeonates of womenWeeks gestational ageWeeks of gestationCohort of womenImminent riskSingleton gestationsParent trialCerebral palsyMultivariable analysisMinimum relative riskRelative riskEnterocolitisNeonatesSecondary analysisWomenMagnesium sulfateA universal mid-trimester transvaginal cervical length screening program and its associated reduced preterm birth rate
Son M, Grobman WA, Ayala NK, Miller ES. A universal mid-trimester transvaginal cervical length screening program and its associated reduced preterm birth rate. American Journal Of Obstetrics And Gynecology 2016, 214: 365.e1-365.e5. PMID: 26928150, DOI: 10.1016/j.ajog.2015.12.020.Peer-Reviewed Original ResearchConceptsWeeks of gestationTransvaginal cervical lengthUniversal cervical lengthPreterm birth rateUniversal transvaginal cervical lengthPrevious preterm birthCervical length measurementCervical lengthPreterm birthBirth rateTransvaginal cervical length measurementPrevious term birthPreterm birth preventionCervical length assessmentSingle tertiary institutionSpontaneous preterm birthUniversal screening programBreslow-Day testShort cervixSingleton gestationsBirth preventionCohort studyEligible womenMultiparous womenTerm births
2015
The effect of chorionic villus sampling on the fraction of cell-free fetal DNA in maternal plasma
Samuel AR, Son M, Ananth CV, Wapner RJ. The effect of chorionic villus sampling on the fraction of cell-free fetal DNA in maternal plasma. The Journal Of Maternal-Fetal & Neonatal Medicine 2015, 29: 2654-2657. PMID: 26482407, DOI: 10.3109/14767058.2015.1095885.Peer-Reviewed Original ResearchConceptsChorionic villus samplingCell-free fetal DNAMaternal plasmaFetal DNABaseline fractionWeeks' gestationCVS groupFirst trimesterPregnant womenCVS patientsFree fetal DNAGenetic testingChorionic villiMean fractionComparison groupVillus samplingWomenPatientsCffDNADaysUltrasoundGroupSubjectsTrimesterGestationClinical indication and timing of antenatal corticosteroid administration at a single centre
Levin HI, Ananth CV, Benjamin-Boamah C, Siddiq Z, Son M, Friedman AM. Clinical indication and timing of antenatal corticosteroid administration at a single centre. BJOG An International Journal Of Obstetrics & Gynaecology 2015, 123: 409-414. PMID: 26485686, DOI: 10.1111/1471-0528.13730.Peer-Reviewed Original ResearchConceptsAntenatal corticosteroidsMajority of womenPreterm birthACS administrationHypertensive disordersPreterm deliveryGestational ageAdministration of ACSOptimal timingAntenatal corticosteroid administrationPositive fetal fibronectinRetrospective cohort studySpontaneous preterm birthTertiary medical centerUltrasound cervical lengthSingleton preterm birthWeeks gestational ageAntenatal steroidsCervical lengthCorticosteroid administrationPreterm laborSteroid administrationCohort studyFetal fibronectinAsymptomatic women
2014
Preterm Premature Rupture of Membranes and the Rate of Neonatal Sepsis After Two Courses of Antenatal Corticosteroids
Gyamfi-Bannerman C, Son M. Preterm Premature Rupture of Membranes and the Rate of Neonatal Sepsis After Two Courses of Antenatal Corticosteroids. Obstetrics And Gynecology 2014, 124: 999-1003. PMID: 25437730, DOI: 10.1097/aog.0000000000000460.Peer-Reviewed Original ResearchConceptsNeonatal sepsisPreterm premature ruptureCorticosteroid coursesPremature ruptureMaternal-fetal medicine unitRespiratory distress syndromeMultivariable logistic regressionStudent's t-testAntenatal corticosteroidsPreterm PROMSingleton gestationsCohort studyPatient characteristicsDistress syndromePrimary outcomeGestational agePrimary exposureBirth weightMedicine unitSepsisSecondary analysisLogistic regressionCategorical variablesT-testLength of time