2020
NMDAR-Dependent Emergence of Behavioral Representation in Primary Visual Cortex
Puścian A, Benisty H, Higley MJ. NMDAR-Dependent Emergence of Behavioral Representation in Primary Visual Cortex. Cell Reports 2020, 32: 107970. PMID: 32726633, PMCID: PMC7431963, DOI: 10.1016/j.celrep.2020.107970.Peer-Reviewed Original ResearchConceptsPrimary visual cortexVisual cortexNMDA-type glutamate receptorsNeocortical sensory areasFunctional plasticityConsiderable functional plasticityPyramidal cellsGlutamate receptorsCell-autonomous expressionV1 neuronsVisual task performanceSensory areasExperience-dependent emergenceCortical networksBehavioral outputCortexVisual inputBehavioral demandsMiceNeuronsReceptors
2019
Layer 5 Circuits in V1 Differentially Control Visuomotor Behavior
Tang L, Higley MJ. Layer 5 Circuits in V1 Differentially Control Visuomotor Behavior. Neuron 2019, 105: 346-354.e5. PMID: 31757603, PMCID: PMC6981039, DOI: 10.1016/j.neuron.2019.10.014.Peer-Reviewed Original ResearchConceptsPyramidal neuronsNeocortical sensory areasPrimary visual cortexDistinct brain areasEyeblink conditioning taskCorticopontine neuronsAxonal projectionsBrain areasCortical subnetworksVisual cortexCalcium imagingVisuomotor behaviorSensory areasOptogenetic manipulationNeuronsConditioning taskDistinct targetsCortexMice