2018
MRI-Ultrasound Fusion Targeted Biopsy of Prostate Imaging Reporting and Data System Version 2 Category 5 Lesions Found False-Positive at Multiparametric Prostate MRI.
Sheridan AD, Nath SK, Aneja S, Syed JS, Pahade J, Mathur M, Sprenkle P, Weinreb JC, Spektor M. MRI-Ultrasound Fusion Targeted Biopsy of Prostate Imaging Reporting and Data System Version 2 Category 5 Lesions Found False-Positive at Multiparametric Prostate MRI. American Journal Of Roentgenology 2018, 210: w218-w225. PMID: 29489409, DOI: 10.2214/ajr.17.18680.Peer-Reviewed Original ResearchConceptsPI-RADS 5 lesionsBenign pathologic resultsLower prostate-specific antigen densitySignificant prostate cancerProstate-specific antigen densityBenign prostatic hyperplasia nodulesMRI-ultrasound fusionProstate Imaging ReportingCategory 5 lesionsPathologic resultsProstate cancerClinical featuresBenign diseaseAntigen densityImaging ReportingGleason 6 diseasePI-RADS version 2High-risk lesionsMultivariate logistic regressionRoutine clinical interpretationMultiparametric prostate MRIInflammatory changesNormal anatomic structuresBiopsy resultsTargeted biopsies
2017
Negative Multiparametric Magnetic Resonance Imaging of the Prostate Predicts Absence of Clinically Significant Prostate Cancer on 12-Core Template Prostate Biopsy
Lu AJ, Syed JS, Nguyen KA, Nawaf CB, Rosoff J, Spektor M, Levi A, Humphrey PA, Weinreb JC, Schulam PG, Sprenkle PC. Negative Multiparametric Magnetic Resonance Imaging of the Prostate Predicts Absence of Clinically Significant Prostate Cancer on 12-Core Template Prostate Biopsy. Urology 2017, 105: 118-122. PMID: 28322902, DOI: 10.1016/j.urology.2017.01.048.Peer-Reviewed Original ResearchConceptsMultiparametric magnetic resonance imagingSignificant prostate cancerProstate cancerNegative predictive valueMagnetic resonance imagingSystematic TRUSNegative mpMRIProstate biopsyNegative multiparametric magnetic resonance imagingPredictive valueResonance imagingClinically Significant Prostate CancerDynamic contrast enhancement sequencesTemplate mapping biopsyPrior negative biopsySystematic prostate biopsyOverall cancer detectionProstate-specific antigenTemplate prostate biopsyProstate cancer detectionDiffusion-weighted imagingCancer detectionBiopsy naïveMapping biopsyProstate volume
2001
Vascular and extravascular complications of liver transplantation: comprehensive evaluation with three-dimensional contrast-enhanced volumetric MR imaging and MR cholangiopancreatography.
Pandharipande P, Lee V, Morgan G, Teperman L, Krinsky G, Rofsky N, Roy M, Weinreb J. Vascular and extravascular complications of liver transplantation: comprehensive evaluation with three-dimensional contrast-enhanced volumetric MR imaging and MR cholangiopancreatography. American Journal Of Roentgenology 2001, 177: 1101-7. PMID: 11641180, DOI: 10.2214/ajr.177.5.1771101.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnastomosis, SurgicalAngiography, Digital SubtractionCholangiographyCholestasis, ExtrahepaticCommon Bile Duct DiseasesFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalLiverLiver TransplantationMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleMiddle AgedPostoperative ComplicationsSensitivity and SpecificityVascular DiseasesConceptsDigital subtraction angiographyMR cholangiopancreatographyLiver transplantSubtraction angiographyMR imagingVolumetric MR imagingConsecutive adult patientsSubset of patientsHepatocellular carcinoma recurrenceMR angiography examinationsMR imaging examinationsBiliary complicationsDisease underestimationExtrahepatic complicationsLiver transplantationAbnormal findingsAdult patientsCarcinoma recurrenceMR imaging strategiesAngiography examinationsVascular diseaseImaging examinationsMost recipientsCholangiopancreatographySimultaneous vascularMR Renography with Low-Dose Gadopentetate Dimeglumine: Feasibility
Lee V, Rusinek H, Johnson G, Rofsky N, Krinsky G, Weinreb J. MR Renography with Low-Dose Gadopentetate Dimeglumine: Feasibility. Radiology 2001, 221: 371-9. PMID: 11687678, DOI: 10.1148/radiol.2212010142.Peer-Reviewed Original ResearchConceptsRenal artery stenosisACE inhibitorsCreatinine levelsIntravenous injectionMedullary enhancementMR renographyAngiotensin converting enzyme (ACE) inhibitorsGadopentetate dimeglumineMR angiographyContrast material-enhanced MR angiographyElevated creatinine levelSerum creatinine levelsMaterial-enhanced MR angiographyConverting Enzyme InhibitorsGadolinium-enhanced MR angiographyRenographic findingsRenovascular diseaseRenal functionArtery stenosisRenal cortexPatientsEnzyme inhibitorsContrast materialClinical settingRenographyHepatocellular Carcinoma and Dysplastic Nodules in Patients with Cirrhosis: Prospective Diagnosis with MR Imaging and Explantation Correlation
Krinsky G, Lee V, Theise N, Weinreb J, Rofsky N, Diflo T, Teperman L. Hepatocellular Carcinoma and Dysplastic Nodules in Patients with Cirrhosis: Prospective Diagnosis with MR Imaging and Explantation Correlation. Radiology 2001, 219: 445-54. PMID: 11323471, DOI: 10.1148/radiology.219.2.r01ma40445.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaDysplastic nodulesMR imagingHistory of HCCSpecificity of MRDetection of HCCMagnetic resonanceDiagnosis of tumorsHepatic arterialHepatic malignanciesPathologic resultsHepatic neoplasmsProspective diagnosisGradient-echo MR imagesMR image interpretationPatient basisLesion basisMR imagesPatientsSubsequent transplantationSpin-echo MR imagesLesions 1Overall sensitivityVolumetric mangafodipir trisodium-enhanced cholangiography to define intrahepatic biliary anatomy.
Lee V, Rofsky N, Morgan G, Teperman L, Krinsky G, Berman P, Weinreb J. Volumetric mangafodipir trisodium-enhanced cholangiography to define intrahepatic biliary anatomy. American Journal Of Roentgenology 2001, 176: 906-8. PMID: 11264075, DOI: 10.2214/ajr.176.4.1760906.Peer-Reviewed Original ResearchDynamic contrast-enhanced three-dimensional MR imaging of liver parenchyma: source images and angiographic reconstructions to define hepatic arterial anatomy.
Lavelle M, Lee V, Rofsky N, Krinsky G, Weinreb J. Dynamic contrast-enhanced three-dimensional MR imaging of liver parenchyma: source images and angiographic reconstructions to define hepatic arterial anatomy. Radiology 2001, 218: 389-94. PMID: 11161151, DOI: 10.1148/radiology.218.2.r01fe31389.Peer-Reviewed Original ResearchSiderotic Nodules in the Cirrhotic Liver at MR Imaging with Explant Correlation: No Increased Frequency of Dysplastic Nodules and Hepatocellular Carcinoma
Krinsky G, Lee V, Nguyen M, Rofsky N, Theise N, Morgan G, Teperman L, Weinreb J. Siderotic Nodules in the Cirrhotic Liver at MR Imaging with Explant Correlation: No Increased Frequency of Dysplastic Nodules and Hepatocellular Carcinoma. Radiology 2001, 218: 47-53. PMID: 11152778, DOI: 10.1148/radiology.218.1.r01ja4047.Peer-Reviewed Original Research
2000
Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: Results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging
Federle M, Chezmar J, Rubin D, Weinreb J, Freeny P, Schmiedl U, Brown J, Borrello J, Lee J, Semelka R, Mattrey R, Dachman A, Saini S, Harms S, Mitchell D, Anderson M, Halford H, Bennett W, Young S, Rifkin M, Gay S, Ballerini R, Sherwin P, Robison R. Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: Results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging. Journal Of Magnetic Resonance Imaging 2000, 12: 689-701. PMID: 11050638, DOI: 10.1002/1522-2586(200011)12:5<689::aid-jmri5>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsUnenhanced magnetic resonance imagingMagnetic resonance imagingMangafodipir trisodium injectionFinal diagnosisMulticenter phase III clinical trialContrast-enhanced computed tomography examinationPhase III clinical trialsContrast-enhanced magnetic resonance imagingInjection of MnDPDPPatient's final diagnosisHepatic magnetic resonance imagingComputed tomography examinationEnhanced magnetic resonance imagingFocal liver diseaseAdditional diagnostic informationFocal liver lesionsLiver diseaseEarly imagingMRI evaluationHepatic massClinical trialsTomography examinationIntravenous administrationPatient managementRadiologic diagnosisSiderotic Nodules at MR Imaging: Regenerative or Dysplastic?
Krinsky G, Lee V, Nguyen M, Rofsky N, Theise N, Morgan G, Teperman L, Weinreb J. Siderotic Nodules at MR Imaging: Regenerative or Dysplastic? Journal Of Computer Assisted Tomography 2000, 24: 773-776. PMID: 11045701, DOI: 10.1097/00004728-200009000-00019.Peer-Reviewed Original ResearchConceptsSiderotic nodulesMR imagingOrthotopic liver transplantationMagnetic resonance imagingSiderotic regenerative nodulesCirrhotic patientsLiver transplantationHypointense nodulesPathologic correlationRegenerative nodulesPatientsResonance imagingPrussian blue iron stainIron stainGradient echo pulse sequenceNodulesImagingMacronodularTransplantationSafety and Efficacy of Mangafodipir Trisodium (MnDPDP) Injection for Hepatic MRI in Adults: Results of the U.S. Multicenter Phase III Clinical Trials (Safety)
Federle M, Chezmar J, Rubin D, Weinreb J, Freeny P, Semelka R, Brown J, Borrello J, Lee J, Mattrey R, Dachman A, Saini S, Harmon B, Fenstermacher M, Pelsang R, Harms S, Mitchell D, Halford H, Anderson M, Johnson C, Francis I, Bova J, Kenney P, Klippenstein D, Foster G, Turner D, Stillman A, Nelson R, Young S, Patt R, Rifkin M, Seltzer S, Gay S, Robison R, Sherwin P, Ballerini R. Safety and Efficacy of Mangafodipir Trisodium (MnDPDP) Injection for Hepatic MRI in Adults: Results of the U.S. Multicenter Phase III Clinical Trials (Safety). Journal Of Magnetic Resonance Imaging 2000, 12: 186-197. PMID: 10931579, DOI: 10.1002/1522-2586(200007)12:1<186::aid-jmri21>3.0.co;2-2.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAdultAgedAged, 80 and overCardiovascular DiseasesContrast MediaDiagnosis, DifferentialEdetic AcidFemaleHumansImage EnhancementInjections, IntravenousLiver CirrhosisLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedPainPregnancyPyridoxal PhosphateRisk AssessmentSensitivity and SpecificityVomitingConceptsMagnetic resonance imagingMangafodipir trisodium injectionAdverse eventsMulticenter phase III clinical trialContrast-enhanced computed tomography examinationPhase III clinical trialsUnenhanced magnetic resonance imagingInjection of MnDPDPInjection-associated discomfortSerious adverse eventsShort-term safetyHepatic magnetic resonance imagingComputed tomography examinationSignificant short-term riskShort-term riskFocal liver lesionsClinical trialsTomography examinationLaboratory valuesLiver lesionsResonance imagingVital signsPatientsMnDPDPInjectionHepatic MR Imaging with a Dynamic Contrast-enhanced Isotropic Volumetric Interpolated Breath-hold Examination: Feasibility, Reproducibility, and Technical Quality
Lee V, Lavelle M, Rofsky N, Laub G, Thomasson D, Krinsky G, Weinreb J. Hepatic MR Imaging with a Dynamic Contrast-enhanced Isotropic Volumetric Interpolated Breath-hold Examination: Feasibility, Reproducibility, and Technical Quality. Radiology 2000, 215: 365-72. PMID: 10796909, DOI: 10.1148/radiology.215.2.r00ma16365.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAdultAgedAged, 80 and overCohort StudiesContrast MediaFeasibility StudiesFemaleFollow-Up StudiesGadolinium DTPAHepatic ArteryHepatic VeinsHumansImage EnhancementImage Processing, Computer-AssistedLiverLiver DiseasesMagnetic Resonance ImagingMaleMiddle AgedPortal VeinQuality ControlReproducibility of ResultsRespirationVena Cava, InferiorConceptsContrast materialMagnetic resonance imaging examinationsPatient underwent repeatVascular anatomic variantsDynamic contrastPortal venous phaseArterial dominanceUnderwent repeatVenous anatomyAnatomic variantsImaging examinationsTest bolusTest doseVenous phaseArterial phaseRepeat studyHepatic MRGadopentetate dimeglumineGradient-echo imagingTechnical qualityEnhanced acquisitionMaximal enhancementBreath-hold imagesOriginal studyAngiotensin-converting enzyme inhibitor-enhanced phase-contrast MR imaging to measure renal artery velocity waveforms in patients with suspected renovascular hypertension.
Lee V, Rofsky N, Ton A, Johnson G, Krinsky G, Weinreb J. Angiotensin-converting enzyme inhibitor-enhanced phase-contrast MR imaging to measure renal artery velocity waveforms in patients with suspected renovascular hypertension. American Journal Of Roentgenology 2000, 174: 499-508. PMID: 10658731, DOI: 10.2214/ajr.174.2.1740499.Peer-Reviewed Original Research
1999
Three-dimensional Gadolinium-enhanced MR Venographic Evaluation of Patency of Central Veins in the Thorax: Initial Experience
Shinde T, Lee V, Rofsky N, Krinsky G, Weinreb J. Three-dimensional Gadolinium-enhanced MR Venographic Evaluation of Patency of Central Veins in the Thorax: Initial Experience. Radiology 1999, 213: 555-60. PMID: 10551241, DOI: 10.1148/radiology.213.2.r99nv27555.Peer-Reviewed Original ResearchConceptsVenographic findingsCentral veinMR venographyCatheter placementConventional venographyCentral venous catheter placementArteriovenous hemodialysis graftsHemodialysis catheter placementThoracic central veinsVenous access sitesMagnetic resonance venographyVenous access devicesVenous catheter placementMultiplanar reconstruction imagesVenographic evaluationFourth patientHemodialysis graftsRetrospective studyMedical recordsAccess siteIntravenous administrationThree-dimensional GadoliniumVenographyPatientsContrast materialAbdominal MR Imaging with a Volumetric Interpolated Breath-hold Examination1
Rofsky N, Lee V, Laub G, Pollack M, Krinsky G, Thomasson D, Ambrosino M, Weinreb J. Abdominal MR Imaging with a Volumetric Interpolated Breath-hold Examination1. Radiology 1999, 212: 876-84. PMID: 10478260, DOI: 10.1148/radiology.212.3.r99se34876.Peer-Reviewed Original ResearchSingle-Dose Breath-hold Gadolinium-enhanced Three-dimensional MR Angiography of the Renal Arteries
Lee V, Rofsky N, Krinsky G, Stemerman D, Weinreb J. Single-Dose Breath-hold Gadolinium-enhanced Three-dimensional MR Angiography of the Renal Arteries. Radiology 1999, 211: 69-78. PMID: 10189455, DOI: 10.1148/radiology.211.1.r99ap4869.Peer-Reviewed Original ResearchConceptsArterial enhancement ratioVenous enhancementRenal arteryTiming examinationContrast materialVascular enhancementMR angiographyBreath holdingContrast material administrationMagnetic resonance angiographyBreath-hold gadoliniumThree-dimensional magnetic resonance angiographyThree-dimensional MR angiographyRenal MR angiographyTest doseArterial enhancementResonance angiographyGadopentetate dimeglumineMaterial administrationAngiographyGradient-echo imagingEnhancement ratioSignificant differencesArteryAortaEcho‐train STIR MRI of the liver: Comparison of breath‐hold and non‐breath‐hold imaging strategies
Earls J, Rofsky N, DeCorato D, Krinsky G, Weinreb J. Echo‐train STIR MRI of the liver: Comparison of breath‐hold and non‐breath‐hold imaging strategies. Journal Of Magnetic Resonance Imaging 1999, 9: 87-92. PMID: 10030655, DOI: 10.1002/(sici)1522-2586(199901)9:1<87::aid-jmri12>3.0.co;2-5.Peer-Reviewed Original Research
1998
The effects of apnea on timing examinations for optimization of gadolinium-enhanced MRA of the thoracic aorta and arch vessels.
Krinsky G, Kaminer E, Lee V, Rofsky N, Weinreb J. The effects of apnea on timing examinations for optimization of gadolinium-enhanced MRA of the thoracic aorta and arch vessels. Journal Of Computer Assisted Tomography 1998, 22: 677-81. PMID: 9754096, DOI: 10.1097/00004728-199809000-00001.Peer-Reviewed Original ResearchConceptsEffects of apneaThoracic aortaGadolinium-enhanced 3D MR angiographyMR angiographyFree breathingArch vesselsTiming examinationGadolinium-enhanced MR angiographyProximal neckIndividual patientsArterial enhancementApneaBranch vesselsGadolinium contrast agentCirculation timePatientsVenous enhancementRespiratory patternLow dosesBreathingAortaAxial imagesMR angiogramsSignificant differencesExaminationMR-Guided Needle Aspiration Biopsies of Hepatic Masses Using a Closed Bore Magnet
Rofsky N, Yang B, Schlossberg P, Goldenberg A, Teperman L, Weinreb J. MR-Guided Needle Aspiration Biopsies of Hepatic Masses Using a Closed Bore Magnet. Journal Of Computer Assisted Tomography 1998, 22: 633-637. PMID: 9676459, DOI: 10.1097/00004728-199807000-00024.Peer-Reviewed Original ResearchConceptsNeedle aspiration biopsyHepatic massAspiration biopsyMR guidanceEfficacy of MRMetastatic carcinomaBiopsy specimensTarget lesionsNoncontrast CTHepatocellular carcinomaHepatic lesionsFocal lesionsBiopsyNecrotic materialBenign hepatocytesPatientsLesionsSmall lesionsMR-compatible needlesNondiagnostic materialPrevious CT
1997
Peripheral vascular disease evaluated with reduced-dose gadolinium-enhanced MR angiography.
Rofsky N, Johnson G, Adelman M, Rosen R, Krinsky G, Weinreb J. Peripheral vascular disease evaluated with reduced-dose gadolinium-enhanced MR angiography. Radiology 1997, 205: 163-9. PMID: 9314979, DOI: 10.1148/radiology.205.1.9314979.Peer-Reviewed Original ResearchConceptsPeripheral vascular diseaseGadolinium-enhanced MR angiographyDigital subtraction angiographyVascular diseaseMR angiographyGadopentetate dimeglumineLower extremity peripheral vascular diseasePeripheral vascular areasExtent of diseaseMR angiography findingsGadolinium-enhanced magnetic resonance angiographyMagnetic resonance angiographyConventional digital subtraction angiographyStandard of referenceAngiography findingsMost patientsLess stenosisTreatment optionsLower extremitiesDSA findingsVascular areaAngiographyAnatomic segmentsAnatomic areasContrast material