Cell membrane penetrating function of the nuclear localization sequence in human cytokine IL-1α
Koo J, Yoon H, Kim W, Lim S, Park H, Choi J. Cell membrane penetrating function of the nuclear localization sequence in human cytokine IL-1α. Molecular Biology Reports 2014, 41: 8117-8126. PMID: 25205122, DOI: 10.1007/s11033-014-3711-7.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell MembraneCell NucleusCell-Penetrating PeptidesHeLa CellsHumansInterleukin-1alphaJurkat CellsMiceNuclear Localization SignalsPeptide FragmentsRecombinant ProteinsTat Gene Products, Human Immunodeficiency VirusConceptsNuclear localization sequenceLocalization sequenceCell penetrating peptideSpecific gene expressionCell membraneEnhanced green fluorescence proteinGreen fluorescence proteinHeparan sulfate interactionProtein delivery efficiencyMembrane penetration abilityGene expressionTAT-CPPFluorescence proteinCellular responsesPrecursor formAmino acidsIntracellular delivery efficiencyProteinDelivery peptidePenetrating peptideSequenceSulfate interactionInterleukin-1 alphaMembraneCells