2024
A smartphone app-based mindfulness intervention to enhance recovery from substance use disorders: Protocol for a pilot feasibility randomized controlled trial
Roos C, Bricker J, Kiluk B, Trull T, Bowen S, Witkiewitz K, Kober H. A smartphone app-based mindfulness intervention to enhance recovery from substance use disorders: Protocol for a pilot feasibility randomized controlled trial. Contemporary Clinical Trials Communications 2024, 41: 101338. DOI: 10.1016/j.conctc.2024.101338.Peer-Reviewed Original ResearchTreatment-as-usualSubstance use disordersRecovery outcomesLong-term recovery outcomesFeasibility of study proceduresFeasibility randomized controlled trialMindfulness-based treatmentsUse disorderRandomized controlled trialsEcological momentary assessmentIn-personMindfulness interventionPilot trialStudy proceduresControlled trialsMomentary assessmentPublic healthEnhanced recoveryOutpatient treatmentMechanical variablesOutcomesTrialsAppsDelivery methodsIndividuals
2020
Evaluating a Longitudinal Mediation Model of Perceived Stress, Depressive Symptoms, and Substance Use Treatment Outcomes
Roos CR, Kiluk BD, McHugh RK, Carroll KM. Evaluating a Longitudinal Mediation Model of Perceived Stress, Depressive Symptoms, and Substance Use Treatment Outcomes. Psychology Of Addictive Behaviors 2020, 34: 660-668. PMID: 32297754, PMCID: PMC7483283, DOI: 10.1037/adb0000581.Peer-Reviewed Original ResearchConceptsIllicit opioid useOpioid useDepressive symptomsUse disordersSubstance use outcomesMethadone treatmentStandard methadone treatmentTrial of galantamineUse outcomesOpioid use disorderSubstance Use Treatment OutcomesSubstance use disordersCocaine use disorderCognitive behavioral therapyLongitudinal treatment studyTreatment outcomesPredictors of endPosttreatment outcomesSymptomsTreatment studiesSignificant total effectSubstance useBaselineOutcomesDisorders
2019
Toward Addiction Prediction: An Overview of Cross-Validated Predictive Modeling Findings and Considerations for Future Neuroimaging Research
Yip SW, Kiluk B, Scheinost D. Toward Addiction Prediction: An Overview of Cross-Validated Predictive Modeling Findings and Considerations for Future Neuroimaging Research. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2019, 5: 748-758. PMID: 31932230, PMCID: PMC8274215, DOI: 10.1016/j.bpsc.2019.11.001.Peer-Reviewed Original ResearchConceptsIndividual differencesBrain-behavior modelsFuture neuroimaging researchLikelihood of replicationEvidence-based treatmentsNeuroimaging researchEffect size estimatesSubstance useDirection of associationAnatomical locusBrain functionTreatment outcomesModeling findingsClinical samplesNovel subjectRelapse rateClinical outcomesPredictive modeling approachUnsuccessful treatmentLeading causeIndividualsClinical settingParticular riskSize estimatesOutcomes
2018
What defines a clinically meaningful outcome in the treatment of substance use disorders: reductions in direct consequences of drug use or improvement in overall functioning?
Kiluk BD, Fitzmaurice GM, Strain EC, Weiss RD. What defines a clinically meaningful outcome in the treatment of substance use disorders: reductions in direct consequences of drug use or improvement in overall functioning? Addiction 2018, 114: 9-15. PMID: 29900624, PMCID: PMC6289694, DOI: 10.1111/add.14289.Peer-Reviewed Original ResearchConceptsSubstance use disordersDrug useUse disordersMost substance use disordersTreatment Efficacy TrialMeaningful outcomesOverall functioningException of alcoholAlcohol-related consequencesAspects of functioningPharmacotherapy trialsEfficacy trialsHealth consequencesIndividual functioningTrialsLong-term functioningWeak associationDisordersCurrent standardFunctioningUse trialOutcomesAssociationAbstinence
2016
Just Showing Up Is Not Enough: Homework Adherence and Outcome in Cognitive–Behavioral Therapy for Cocaine Dependence
Decker SE, Kiluk BD, Frankforter T, Babuscio T, Nich C, Carroll KM. Just Showing Up Is Not Enough: Homework Adherence and Outcome in Cognitive–Behavioral Therapy for Cocaine Dependence. Journal Of Consulting And Clinical Psychology 2016, 84: 907-912. PMID: 27454780, PMCID: PMC5341374, DOI: 10.1037/ccp0000126.Peer-Reviewed Original ResearchConceptsUrine toxicology screenCognitive behavioral therapyCocaine use outcomesHomework adherenceTreatment attendanceToxicology screenCocaine useUse outcomesMultiple logistic regressionBaseline cocaine useVariety of disordersCocaine use severityTreatment endClinical trialsCocaine use frequencyImproved outcomesCocaine dependenceLogistic regressionCBT sessionsAdherenceUse severityPrior studiesGreater reductionOutcomesTreatmentAnger and Its Association with Substance Use Treatment Outcomes in a Sample of Adolescents
Serafini K, Toohey MJ, Kiluk BD, Carroll KM. Anger and Its Association with Substance Use Treatment Outcomes in a Sample of Adolescents. Journal Of Child & Adolescent Substance Abuse 2016, 25: 391-398. PMID: 28373792, PMCID: PMC5375034, DOI: 10.1080/1067828x.2015.1049394.Peer-Reviewed Original ResearchPre-treatment responsesTreatment outcomesSubstance Use Treatment OutcomesDrug Abuse Treatment Outcome StudyTreatment outcome studiesPoor outcomeDelirium tremensOutcome studiesPattern of responseTemper outburstsHigh angerAlcohol useGreater likelihoodSample of adolescentsTreatment literatureOutcomesAdolescentsLow angerTremens
2015
Outcome expectations and associated treatment outcomes in motivational enhancement therapy delivered in English and Spanish
Serafini K, Decker S, Kiluk BD, Añez L, Paris M, Frankforter T, Carroll KM. Outcome expectations and associated treatment outcomes in motivational enhancement therapy delivered in English and Spanish. American Journal On Addictions 2015, 24: 732-739. PMID: 26541501, PMCID: PMC4885684, DOI: 10.1111/ajad.12301.Peer-Reviewed Original ResearchConceptsPatients' outcome expectationsTreatment outcomesMotivational enhancement therapyEnhancement therapyUrine toxicology screenLikelihood of abstinenceSubstance use disordersSubstance use outcomesToxicology screenClinical trialsTreatment periodUse disordersOutcome expectationsSecondary analysisSubstance useAbstinenceUse outcomesOutcomesMetSTherapyTreatmentBaseline expectationsGreater percentageSame treatmentImportant predictor
2013
Smokers Versus Snorters: Do Treatment Outcomes Differ According to Route of Cocaine Administration?
Kiluk BD, Babuscio TA, Nich C, Carroll KM. Smokers Versus Snorters: Do Treatment Outcomes Differ According to Route of Cocaine Administration? Experimental And Clinical Psychopharmacology 2013, 21: 490-498. PMID: 24364538, PMCID: PMC3943602, DOI: 10.1037/a0034173.Peer-Reviewed Original ResearchConceptsTreatment outcomesCocaine administrationAddiction Severity Index composite scoresIntranasal usersComposite scoreRoute of administrationCocaine use outcomesPrimary routeIntranasal routeClinical trialsSustained abstinenceCocaine-dependent individualsTreatment phaseSmokersCocaine useStudy periodAdministrationUse outcomesSeverity of problemsMaximal concentrationStatistical significanceASI domainsOutcomesDifferential changesCocaine