Sunil Koundal
Research ScientistDownloadHi-Res Photo
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Contact Info
Yale School of Medicine
1 GILBERT ST, The anlyan center, N142
NEW HAVEN, Connecticut 06519
United States
About
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Titles
Research Scientist
Appointments
Anesthesiology
Research ScientistPrimary
Other Departments & Organizations
Education & Training
- Post Doctoral associate
- Yale School of Medicine (2020)
- PhD
- Panjab University, Biophysics (2017)
- MSc
- Delhi University, Biomedical Sciences (2010)
- BSc
- Himachal University, Biotechnology (2008)
Research
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Overview
Medical Research Interests
Magnetic Resonance Imaging; Nuclear Magnetic Resonance, Biomolecular
Public Health Interests
Aging; Biomarkers; Metabolism; Metabolomics
ORCID
0000-0003-3969-1091
Research at a Glance
Yale Co-Authors
Frequent collaborators of Sunil Koundal's published research.
Publications Timeline
A big-picture view of Sunil Koundal's research output by year.
Research Interests
Research topics Sunil Koundal is interested in exploring.
Helene Benveniste, MD, PhD
Zachary Gursky, PhD
Burhan Ozturk
Hung-Mo Lin
Alvaro Duque, PhD
Anne Eichmann, PhD
19Publications
576Citations
Magnetic Resonance Imaging
Publications
2026
Chronic Hypertension Impairs Lymphatic Drainage in Deep Cervical Lymph Nodes
Xu K, Bhardwaj A, Koundal S, Ren Q, You C, Papademetris X, Benveniste H, Georgiou T. Chronic Hypertension Impairs Lymphatic Drainage in Deep Cervical Lymph Nodes. JCI Insight 2026 PMID: 42585123, DOI: 10.1172/jci.insight.206714.Peer-Reviewed Original ResearchCitationsCerebral venous blood flow regulates intracerebral pressure and brain clearance via meningeal lymphatic vessels
El Kamouh M, Spajer M, Singhabahu R, Joly Marolany A, Sailor K, Mouton L, Doukhi D, Koundal S, Metcalfe T, Langui D, Grine A, Boyé K, Saceanu Leser F, Ninnemann J, Gottschalk J, Sadeghi C, Xu H, Akbar D, Van Wassenhove J, Ruze A, Nasri A, Bourrienne M, Buscher E, Hong Y, Mazighi M, Lledo P, Benveniste H, Santin M, Eichmann A, Lehericy S, Thomas J, Lenck S. Cerebral venous blood flow regulates intracerebral pressure and brain clearance via meningeal lymphatic vessels. Nature Neuroscience 2026, 29: 2190-2203. PMID: 42487032, PMCID: PMC13533833, DOI: 10.1038/s41593-026-02358-1.Peer-Reviewed Original ResearchAltmetric
2025
A novel gene edited rat model of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)
Monte B, Davis J, Zhu X, Xu F, Majchrzak M, Cabral M, Van Nostrand W, Healey B, Koundal S, Lee H, Robinson J, Benveniste H, Van Nostrand W. A novel gene edited rat model of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). Cerebral Circulation - Cognition And Behavior 2025, 9: 100401. PMID: 41142321, PMCID: PMC12546807, DOI: 10.1016/j.cccb.2025.100401.Peer-Reviewed Original ResearchCitationsAltmetricAge-dependent brain responses to mechanical stress determine resilience in a chronic lymphatic drainage impairment model
Gursky Z, Khan Z, Koundal S, Bhardwaj A, Melgarejo J, Xu K, Chen X, Lin H, Gu X, Kipnis J, Dori Y, Tannenbaum A, Santambrogio L, Benveniste H. Age-dependent brain responses to mechanical stress determine resilience in a chronic lymphatic drainage impairment model. Journal Of Clinical Investigation 2025, 135: e182555. PMID: 40663395, PMCID: PMC12404751, DOI: 10.1172/jci182555.Peer-Reviewed Original ResearchCitationsAltmetric
2024
Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease
Koundal S, Chen X, Gursky Z, Xu K, Liang F, Xie Z, Xu F, Lin H, Van Nostrand W, Gu X, Elkin R, Tannenbaum A, Benveniste H. Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease. IScience 2024, 27: 111463. PMID: 39720539, PMCID: PMC11667077, DOI: 10.1016/j.isci.2024.111463.Peer-Reviewed Original ResearchCitationsAltmetric
2023
Author Correction: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries
Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Kipnis J, Tannenbaum A, Van Nostrand W, Benveniste H. Author Correction: Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries. Nature Aging 2023, 3: 1603-1603. PMID: 38001312, DOI: 10.1038/s43587-023-00544-5.Commentaries, Editorials and LettersCitationsAltmetricContinuous positive airway pressure (CPAP) increases CSF flow and glymphatic transport
Ozturk B, Koundal S, Al Bizri E, Chen X, Gursky Z, Dai F, Lim A, Heerdt P, Kipnis J, Tannenbaum A, Benveniste H. Continuous positive airway pressure (CPAP) increases CSF flow and glymphatic transport. JCI Insight 2023, 8: e170270. PMID: 37159262, PMCID: PMC10371231, DOI: 10.1172/jci.insight.170270.Peer-Reviewed Original ResearchCitationsAltmetricThe choroid plexus links innate immunity to CSF dysregulation in hydrocephalus
Reeves B, Kiziltug E, Duy P, Karimy J, Mansuri M, Marlier A, Greenberg A, DeSpenza T, Singh A, Zeng X, Mekbib K, Nelson-Williams C, Hao L, Zhang J, Lam T, Wilson R, Butler W, Diluna M, Feinberg P, Schafer D, Movahedi K, Tannenbaum A, Koundal S, Chen X, Benveniste H, Limbrick D, Schiff S, Carter B, Gunel M, Simard J, Lifton R, Alper S, Delpire E, Kahle K. The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus. Cell 2023, 186: 764-785.e21. PMID: 36803604, PMCID: PMC10069664, DOI: 10.1016/j.cell.2023.01.017.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Choroid plexus tissue perfusion and blood to CSF barrier function in rats measured with continuous arterial spin labeling
Ozturk B, Stringer MS, Koundal S, MacIntosh BJ, Rothman D, Benveniste H. Choroid plexus tissue perfusion and blood to CSF barrier function in rats measured with continuous arterial spin labeling. NeuroImage 2022, 261: 119512. PMID: 35882269, PMCID: PMC9969358, DOI: 10.1016/j.neuroimage.2022.119512.Peer-Reviewed Original ResearchCitationsCharacterization of perivascular space pathology in a rat model of cerebral small vessel disease by in vivo magnetic resonance imaging
Monte B, Constantinou S, Koundal S, Dai F, Gursky Z, Van Nostrand WE, Zlokovic BV, Wardlaw J, Benveniste H. Characterization of perivascular space pathology in a rat model of cerebral small vessel disease by in vivo magnetic resonance imaging. Journal Of Cerebral Blood Flow And Metabolism : Official Journal Of The International Society Of Cerebral Blood Flow And Metabolism 2022, 42: 1813-1826. PMID: 35673963, PMCID: PMC9536121, DOI: 10.1177/0271678x221105668.Peer-Reviewed Original ResearchCitationsAltmetric
Academic Achievements & Community Involvement
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Honors
honor Travel grant
09/17/2024Other Award American College of NeuropsychopharmacologyDetailsUnited Stateshonor Magna Cum Laude Award
05/16/2019International AwardInternational Society for Magnetic Resonance in MedicineDetailsCanada
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Mailing Address
Yale School of Medicine
1 GILBERT ST, The anlyan center, N142
NEW HAVEN, Connecticut 06519
United States