2004
Effects of ε-Aminocaproic Acid and Aprotinin on Leukocyte–Platelet Adhesion in Patients Undergoing Cardiac Surgery
Greilich PE, Brouse CF, Rinder CS, Smith BR, Sandoval BA, Rinder HM, Eberhart RC, Jessen ME. Effects of ε-Aminocaproic Acid and Aprotinin on Leukocyte–Platelet Adhesion in Patients Undergoing Cardiac Surgery. Anesthesiology 2004, 100: 225-233. PMID: 14739793, DOI: 10.1097/00000542-200402000-00008.Peer-Reviewed Original ResearchConceptsEpsilon-aminocaproic acidCardiopulmonary bypassLeukocyte-platelet adhesionPlatelet activationPlatelet CD62PCardiac surgeryPlasmin activityAdministration of aprotininDouble-blind fashionMonocyte-platelet conjugatesActivation of leukocytesD-dimer formationConjugate formationAbility of aprotininMonocyte CD11bSaline groupCD11b expressionLeukocyte activationΕ-aminocaproic acidPatientsUseful markerClinical settingAprotininLeukocytesSurgery
2003
Increased leukocyte-platelet adhesion in patients with graft occlusion after peripheral vascular surgery
Esposito CJ, Popescu WM, Rinder HM, Schwartz JJ, Smith BR, Rinder CS. Increased leukocyte-platelet adhesion in patients with graft occlusion after peripheral vascular surgery. Thrombosis And Haemostasis 2003, 90: 1128-1134. PMID: 14652647, DOI: 10.1160/th03-04-0226.Peer-Reviewed Original ResearchConceptsPeripheral vascular diseasePeripheral vascular surgeryGraft occlusionLeukocyte-platelet adhesionOcclusion groupPlatelet turnoverVascular surgeryPMN activationPeripheral vascular surgery patientsLower extremity peripheral vascular diseaseEtiology of thrombosisVascular surgery patientsLate graft occlusionEarly postoperative periodSurface CD11b expressionProgression of atherosclerosisGraft lossPVD patientsGraft patientsPostoperative dayPostoperative periodSurgery patientsAcute thrombosisGraft patencyVascular disease
1994
Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*
Rinder H, Tracey J, Rinder C, Leitenberg D, Smith B. Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*. Thrombosis And Haemostasis 1994, 72: 750-756. PMID: 7534948, DOI: 10.1055/s-0038-1648953.Peer-Reviewed Original ResearchConceptsNeutrophil-platelet conjugatesP-selectinP-selectin-mediated platelet adhesionDREG-56Platelet activationL-selectinPlatelet P-selectin expressionP-selectin-expressing plateletsP-selectin-positive plateletsLeukocyte-platelet conjugatesNeutrophil-platelet adhesionPlatelet P-selectinP-selectin expressionWhole blood modelLeukocyte-platelet adhesionPlatelet adhesionNeutrophil activationLeukocyte activationNeutrophil adhesionBaseline levelsNeutrophilsUnstimulated leukocytesMonoclonal antibodiesEndothelial cellsImmediate rise
1992
Cardiopulmonary Bypass Induces Leukocyte-Platelet Adhesion
Rinder C, Bonan J, Rinder H, Mathew J, Hines R, Smith B. Cardiopulmonary Bypass Induces Leukocyte-Platelet Adhesion. Blood 1992, 79: 1201-1205. PMID: 1371416, DOI: 10.1182/blood.v79.5.1201.1201.Peer-Reviewed Original ResearchConceptsLeukocyte-platelet conjugatesCardiopulmonary bypassMonocyte-platelet conjugatesEnd of CPBStart of CPBActivation of monocytesAlpha-granule releaseGMP-140 expressionGranule membrane protein-140Time courseLeukocyte-platelet adhesionCD11b expressionMonocyte activationSurface CD11bWhole bloodGMP-140Surface expressionProtein 140Increased numberCD11bBypassMonocytesPlateletsPlatelet adhesionConjugatesCardiopulmonary bypass induces leukocyte-platelet adhesion
Rinder C, Bonan J, Rinder H, Mathew J, Hines R, Smith B. Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood 1992, 79: 1201-1205. DOI: 10.1182/blood.v79.5.1201.bloodjournal7951201.Peer-Reviewed Original ResearchLeukocyte-platelet conjugatesCardiopulmonary bypassMonocyte-platelet conjugatesEnd of CPBStart of CPBActivation of monocytesAlpha-granule releaseGMP-140 expressionGranule membrane protein-140Time courseLeukocyte-platelet adhesionCD11b expressionMonocyte activationSurface CD11bWhole bloodGMP-140Surface expressionProtein 140Increased numberCD11bBypassMonocytesPlateletsPlatelet adhesionConjugates