2024
Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study
Estroff J, Devlin J, Hoteit L, Hassoune A, Neal M, Brown J, Lu L, Kotch S, Hazelton J, Christian A, Yeates E, Nahmias J, Jacobson L, Williams J, Schuster K, O'Connor R, Semon G, Straughn A, Cullinane D, Egodage T, Kincaid M, Rollins A, Amdur R, Sarani B. Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study. Journal Of Trauma And Acute Care Surgery 2024, 97: 541-545. PMID: 38685190, DOI: 10.1097/ta.0000000000004345.Peer-Reviewed Original ResearchProthrombin complex concentrateAmount of RBC transfusionRed blood cell transfusionAndexanet alfaRed blood cellsRBC transfusionMulticenter study of adult patientsNon-inferiorityComparing prothrombin complex concentrateOral factor Xa inhibitorsStudy of adult patientsTransfused red blood cellsIncreased RBC transfusionsReversal of DOACsComplex concentrateFactor Xa inhibitorsTreatment of hemorrhageTraumatically injured patientsDOAC reversalMedian transfusionTransfusion rateUnit transfusionsMulticenter studyAdult patientsXa inhibitors
2020
Transfusion rates in emergency general surgery: high but modifiable
Medvecz A, Bernard A, Hamilton C, Schuster KM, Guillamondegui O, Davenport D. Transfusion rates in emergency general surgery: high but modifiable. Trauma Surgery & Acute Care Open 2020, 5: e000371. PMID: 32154373, PMCID: PMC7046949, DOI: 10.1136/tsaco-2019-000371.Peer-Reviewed Original ResearchNational Surgical Quality Improvement Program dataTransfusion rateRed blood cellsRBC transfusionSurgeons National Surgical Quality Improvement Program dataEmergency general surgery casesQuality Improvement Program dataBlood conservation technologiesNon-emergent casesCurrent Procedural Terminology codesEmergency general surgeryGeneral surgery casesProcedural Terminology codesAcademic medical centerComposite morbidityNSQIP complicationsRetrospective reviewSurgery casesGeneral surgeonsMedical CenterAmerican CollegeGeneral surgeryTerminology codesTransfusionPatient acuity
2016
The confusion continues: results from an American Association for the Surgery of Trauma survey on massive transfusion practices among United States trauma centers
Etchill E, Sperry J, Zuckerbraun B, Alarcon L, Brown J, Schuster K, Kaplan L, Piper G, Peitzman A, Neal MD. The confusion continues: results from an American Association for the Surgery of Trauma survey on massive transfusion practices among United States trauma centers. Transfusion 2016, 56: 2478-2486. PMID: 27515056, DOI: 10.1111/trf.13755.Peer-Reviewed Original ResearchConceptsMassive transfusion protocolMassive transfusion practiceMTP activationTransfusion practiceScoring systemTranexamic acidUnited States trauma centersPartial thromboplastin time (aPTT) testingTEG/ROTEMInternational normalized ratioStates trauma centersCare prothrombin timeOutcome-based studiesAmerican AssociationNontrauma patientsRed blood cellsTransfusion protocolTrauma centerHemostatic resuscitationMassive hemorrhageNormalized ratioRotational thromboelastometryProthrombin timeLevel INontrauma indications
2010
The status of massive transfusion protocols in United States trauma centers: massive transfusion or massive confusion?
Schuster KM, Davis KA, Lui FY, Maerz LL, Kaplan LJ. The status of massive transfusion protocols in United States trauma centers: massive transfusion or massive confusion? Transfusion 2010, 50: 1545-1551. PMID: 20158684, DOI: 10.1111/j.1537-2995.2010.02587.x.Peer-Reviewed Original ResearchConceptsFresh frozen plasmaRed blood cellsTrauma surgeonsRatio of FFPUnited States trauma centersMassive transfusion protocolStates trauma centersSurgery of TraumaTransfusion protocolMassive transfusionTrauma centerEmergency departmentMost centersEastern AssociationAnesthesia staffWeb-based surveyLogistic regressionRBC ratioBlood bankStudy designBlood cellsOperating roomSurgeonsSurgeryProtocol utilization