2023
Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions.
Hong C, Lamsam L, Yadlapalli V, Parasuram N, Mazurek M, Chavva I, Lalwani D, Zabinska J, Schiff S, Manes R, Vining E, Rimmer R, Kimberly W, Sheth K, Omay S. Portable MRI to assess optic chiasm decompression after endoscopic endonasal resection of sellar and suprasellar lesions. Journal Of Neurosurgery 2023, 139: 1664-1670. PMID: 37347618, DOI: 10.3171/2023.5.jns23174.Peer-Reviewed Original ResearchConceptsEndoscopic endonasal surgeryOptic nerve decompressionEndonasal surgerySuprasellar lesionsNerve decompressionOptic chiasmThird ventricleConventional MRIOptic chiasm compressionEndoscopic endonasal resectionChiasm compressionPreoperative imagingSingle institutionEndonasal resectionMRI availabilityRoutine MRISignificant interrater reliabilitySuprasellar pathologiesSurgeryNeurosurgical oncologyLinear mixed-effects modelsPortable MRIPatientsMRIMixed-effects models
2021
PATH-38. APC MUTATION AS A DRIVER ONCOGENE IN NON-CTNNB1 MUTANT ADAMANTINOMATOUS CRANIOPHARYNGIOMAS
Hong C, Erson-Omay Z, Omay S. PATH-38. APC MUTATION AS A DRIVER ONCOGENE IN NON-CTNNB1 MUTANT ADAMANTINOMATOUS CRANIOPHARYNGIOMAS. Neuro-Oncology 2021, 23: vi123-vi123. PMCID: PMC8598823, DOI: 10.1093/neuonc/noab196.490.Peer-Reviewed Original ResearchAdamantinomatous craniopharyngiomaInstitutional review board-approved protocolCTNNB1 mutationsFamilial adenomatous polyposisWhole-exome sequencingAPC mutationsNeurological deficitsVentricular involvementOptic apparatusClassic subtypeStop codon mutationMalignant tumorsThird ventricleBRAF inhibitorsCraniopharyngeal ductDriver oncogenesTherapeutic strategiesMAP kinase/ERKCraniopharyngiomaGermline APC mutationsPapillary craniopharyngiomasPituitary glandAdenomatous polyposisPathogenic variantsEmbryonic remnants
2019
5 Suprasellar Pathology
Omay S, Anand V, Schwartz T. 5 Suprasellar Pathology. 2019, 61-69. DOI: 10.1007/978-3-319-64379-3_5.Peer-Reviewed Original ResearchSuprasellar lesionsCareful patient selectionVisual field lossEndonasal endoscopic approachEndocrine dysfunctionOptic nerveOptic apparatusPatient selectionSurgical interventionMicroneurosurgical approachesBrain retractionEndoscopic approachPituitary adenomasCarotid arteryEndoscopic methodsThird ventricleEndoscopic techniquesField lossPituitary glandSuprasellar pathologiesLesionsPathologyHydrocephalusTransplanumNerve
2017
Is the chiasm-pituitary corridor size important for achieving gross-total resection during endonasal endoscopic resection of craniopharyngiomas?
Omay SB, Almeida JP, Chen YN, Shetty SR, Liang B, Ni S, Anand VK, Schwartz TH. Is the chiasm-pituitary corridor size important for achieving gross-total resection during endonasal endoscopic resection of craniopharyngiomas? Journal Of Neurosurgery 2017, 129: 642-647. PMID: 29171802, DOI: 10.3171/2017.6.jns163188.Peer-Reviewed Original ResearchConceptsGross total resectionExtended endonasal approachSubtotal resectionLarge tumorsPituitary glandFirst-line surgical approachEndonasal endoscopic resectionAvailable preoperative imagingMidline craniopharyngiomasOBJECTIVE CraniopharyngiomasPrefixed chiasmEndocrine outcomesRelative contraindicationVisual outcomeEndoscopic resectionAuthors' centerPreoperative imagingOptic chiasmSurgical approachVisual deteriorationResults ThirtyPituitary stalkThird ventricleHigh riskResection