2024
Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis
Ram C, Yousef S, Ma W, Vallabhajosyula I, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Williams M, Geirsson A, Vallabhajosyula P. Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis. Scientific Reports 2024, 14: 4952. PMID: 38418864, PMCID: PMC10902341, DOI: 10.1038/s41598-024-52660-w.Peer-Reviewed Original ResearchConceptsAortic valve replacementSevere aortic stenosisAfrican American raceArea Deprivation IndexAortic stenosisSevere ASArea deprivation index rankAortic valve replacement ratesAmerican raceAortic valve interventionPresentation of sepsisDiagnosis of ASADI groupValve replacementValve interventionDeprived neighbourhoodsAV interventionDisadvantaged neighborhoodsPatientsFemale genderDeprivation indexHigh-ADI groupLow-ADI groupStenosisRace
2018
Functional Outcomes of Type I Bicuspid Aortic Valve Repair With Annular Stabilization: Subcommissural Annuloplasty Versus External Subannular Aortic Ring
Ko H, Bavaria JE, Habertheuer A, Augoustides JG, Siki MA, Freas M, Komlo C, Milewski K, Desai ND, Szeto WY, Vallabhajosyula P. Functional Outcomes of Type I Bicuspid Aortic Valve Repair With Annular Stabilization: Subcommissural Annuloplasty Versus External Subannular Aortic Ring. The Annals Of Thoracic Surgery 2018, 107: 68-75. PMID: 30086284, DOI: 10.1016/j.athoracsur.2018.06.056.Peer-Reviewed Original ResearchConceptsSubcommissural annuloplastyAortic insufficiencyAortic valve repairTransvalvular gradientValve repairAortic ringsLeaflet prolapseAnnular stabilizationVentricular outflow tract diameterBicuspid aortic valve patientsBicuspid aortic valve repairOutflow tract diameterSevere aortic insufficiencyMean transvalvular gradientIntraoperative transesophageal echocardiographyAortic valve patientsLV outflow tractAortic root complexPostprocedure outcomesValve patientsTract diameterFunctional outcomeLV dimensionsTransesophageal echocardiographyOutflow tractPredictors of Recurrent Aortic Insufficiency in Type I Bicuspid Aortic Valve Repair
Habertheuer A, Milewski RK, Bavaria JE, Siki M, Freas M, Desai N, Szeto W, Ram C, Hu R, Vallabhajosyula P. Predictors of Recurrent Aortic Insufficiency in Type I Bicuspid Aortic Valve Repair. The Annals Of Thoracic Surgery 2018, 106: 1316-1324. PMID: 30055138, DOI: 10.1016/j.athoracsur.2018.06.026.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAgedAortic ValveAortic Valve InsufficiencyBicuspid Aortic Valve DiseaseCardiac Valve AnnuloplastyDatabases, FactualFemaleFollow-Up StudiesHeart Valve DiseasesHeart Valve ProsthesisHumansLogistic ModelsMaleMiddle AgedPredictive Value of TestsRecurrenceReoperationRetrospective StudiesRisk AssessmentSurvival RateTreatment OutcomeHemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves.
Mangels DR, Siki M, Menon R, Bavaria J, Anwaruddin S, Giri J, Desai N, Szeto WY, Vallabhajosyula P, Herrmann HC. Hemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves. Journal Of Invasive Cardiology 2018, 30: 138-143. PMID: 29610444.Peer-Reviewed Original ResearchConceptsStructural valve deteriorationTranscatheter aortic valve replacementSAPIEN 3 valveParavalvular leakTransthoracic echocardiogramAortic insufficiencySAPIEN 3 transcatheter aortic valveAortic valve gradientSapien 3 prosthesisAortic valve replacementRetrospective cohort analysisTranscatheter aortic valveAI severityValve gradientAnnular calcificationHemodynamic effectsValve replacementValve deteriorationSmall prosthesisSingle institutionAortic valveAV gradientCohort analysisHigh incidenceSignificant differencesManagement of the moderately dilated sinus of Valsalva: To cut or not to cut?
Milewski RK, Habertheuer A, Bavaria JE, Vallabhajosyula P. Management of the moderately dilated sinus of Valsalva: To cut or not to cut? Journal Of Thoracic And Cardiovascular Surgery 2018, 155: 526-527. PMID: 29415375, DOI: 10.1016/j.jtcvs.2017.10.002.Peer-Reviewed Original Research
2017
Aortic Leaflet Billowing as a Risk Factor for Repair Failure After Aortic Valve Repair
Ridley C, Sohmer B, Vallabhajosyula P, Augoustides JGT. Aortic Leaflet Billowing as a Risk Factor for Repair Failure After Aortic Valve Repair. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 31: 1001-1006. PMID: 28457780, DOI: 10.1053/j.jvca.2017.02.019.Peer-Reviewed Original Research
2016
Valve Selection in End-Stage Renal Disease: Should It Always Be Biological?
Williams ML, Bavaria JE, Acker MA, Desai ND, Vallabhajosyula P, Hargrove WC, Atluri P, Szeto WY. Valve Selection in End-Stage Renal Disease: Should It Always Be Biological? The Annals Of Thoracic Surgery 2016, 102: 1531-1535. PMID: 27544289, DOI: 10.1016/j.athoracsur.2016.04.092.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAnticoagulantsAortic ValveBioprosthesisCalcinosisContraindicationsEndocarditisHeart Valve DiseasesHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansKaplan-Meier EstimateKidney Failure, ChronicMiddle AgedMitral ValvePostoperative ComplicationsProportional Hazards ModelsProsthesis-Related InfectionsRenal DialysisRetrospective StudiesThrombophiliaConceptsEnd-stage renal diseaseValve replacementProportional hazards modelESRD patientsMechanical valvesRenal diseaseHazards modelImproved long-term survivalCox proportional hazards modelAortic valve replacementMechanical valve replacementMitral valve replacementKaplan-Meier methodLong-term survivalValve selectionESRD populationPatient ageUnadjusted survivalImproved survivalPatient populationPatientsSurvivalDiseaseMinimal differencesYearsNew Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement.
Rene AG, Jagasia D, Wickramasinghe SR, Desai N, Szeto W, Vallabhajosyula P, Li RH, Silvestry FE, Giri J, Jha S, Herrmann HC, Anwaruddin S. New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement. Journal Of Invasive Cardiology 2016, 28: e59-65. PMID: 27342207.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic ValveAortic Valve StenosisEchocardiographyFemaleHeart Septal Defects, VentricularHumansMaleOutcome and Process Assessment, Health CarePostoperative ComplicationsQuality of LifeReoperationRisk AssessmentRisk FactorsSeverity of Illness IndexTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementLeft ventricular outflow tract calcificationSevere symptomatic aortic stenosisVentricular outflow tract calcificationSymptomatic aortic stenosisAortic valve replacementVentricular septal defectNew ventricular septal defectQuality of lifeInoperable patientsInfrequent complicationParavalvular regurgitationValve replacementAortic stenosisVascular injurySeptal defectPatientsComplicationsStudied populationRegurgitationStenosisInjuryStrokeCalcificationBicuspid Aortic Insufficiency With Aortic Root Aneurysm: Root Reimplantation Versus Bentall Root Replacement
Vallabhajosyula P, Szeto WY, Habertheuer A, Komlo C, Milewski RK, McCarthy F, Desai ND, Bavaria JE. Bicuspid Aortic Insufficiency With Aortic Root Aneurysm: Root Reimplantation Versus Bentall Root Replacement. The Annals Of Thoracic Surgery 2016, 102: 1221-1228. PMID: 27261086, DOI: 10.1016/j.athoracsur.2016.03.087.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicAortic Aneurysm, ThoracicAortic ValveAortic Valve InsufficiencyBicuspid Aortic Valve DiseaseBlood Vessel Prosthesis ImplantationCombined Modality TherapyDatabases, FactualEchocardiography, TransesophagealFemaleFollow-Up StudiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHumansMaleMiddle AgedPreoperative CareRetrospective StudiesRisk AssessmentSurvival RateTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsAortic insufficiencyBicuspid aortic valveBentall groupRoot replacementRoot reimplantationAortic valveCusp repairRoot aneurysmFive-year actuarial survivalValve-sparing root reimplantationBicuspid aortic insufficiencyHospital stroke ratePermanent pacemaker rateTransient ischemic attackVentricular diastolic diameterLow ejection fractionAortic root aneurysmAortic root proceduresActuarial survivalAortic reoperationDischarge echocardiographyHospital mortalityIschemic attackVSRR groupBentall procedureSurgical Aortic Valve Replacement—Clinical Update on Recent Advances in the Contemporary Era
Ramakrishna H, Patel PA, Gutsche JT, Vallabhajosyula P, Szeto WY, MacKay E, Feinman JW, Shah R, Zhou E, Weiss SJ, Augoustides JG. Surgical Aortic Valve Replacement—Clinical Update on Recent Advances in the Contemporary Era. Journal Of Cardiothoracic And Vascular Anesthesia 2016, 30: 1733-1741. PMID: 27542900, DOI: 10.1053/j.jvca.2016.04.014.Peer-Reviewed Educational MaterialsTransfemoral transcatheter valve-in-valve-in-valve replacement
Sang S, Giri J, Vallabhajosyula P. Transfemoral transcatheter valve-in-valve-in-valve replacement. Journal Of Thoracic And Cardiovascular Surgery 2016, 152: 622-623. PMID: 27179844, DOI: 10.1016/j.jtcvs.2016.03.047.Peer-Reviewed Original ResearchThe Sievers Classification of the Bicuspid Aortic Valve for the Perioperative Echocardiographer: The Importance of Valve Phenotype for Aortic Valve Repair in the Era of the Functional Aortic Annulus
Ridley CH, Vallabhajosyula P, Bavaria JE, Patel PA, Gutsche JT, Shah R, Feinman JW, Weiss SJ, Augoustides JG. The Sievers Classification of the Bicuspid Aortic Valve for the Perioperative Echocardiographer: The Importance of Valve Phenotype for Aortic Valve Repair in the Era of the Functional Aortic Annulus. Journal Of Cardiothoracic And Vascular Anesthesia 2016, 30: 1142-1151. PMID: 27241768, DOI: 10.1053/j.jvca.2016.02.009.Peer-Reviewed Educational Materials
2015
Aortic Annulus Diameter Affects Durability of the Repaired Bicuspid Aortic Valve.
Vallabhajosyula P, Komlo CM, Szeto WY, Rhode T, Menon R, Desai ND, Bavaria JE. Aortic Annulus Diameter Affects Durability of the Repaired Bicuspid Aortic Valve. The Journal Of Heart Valve Disease 2015, 24: 412-9. PMID: 26897808.Peer-Reviewed Original ResearchMeSH KeywordsAdultAortic ValveAortic Valve InsufficiencyBicuspid Aortic Valve DiseaseCardiac Valve AnnuloplastyChi-Square DistributionDisease-Free SurvivalFemaleHeart Valve DiseasesHumansKaplan-Meier EstimateMaleMiddle AgedOdds RatioRecurrenceReplantationRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeConceptsValve-sparing root reimplantationFive-year freedomSubcommissural annuloplastyAnnular diameterSCA groupAI gradeSCA subgroupsBicuspid aortic valve repairAortic insufficiency gradeAortic annular diameterBicuspid aortic valveAortic annulus diameterAortic valve repairBAV repairVSRR groupVSRR patientsMidterm outcomesBAV patientsAortic annulusRetrospective reviewRoot reimplantationValve repairAortic valveUnivariate analysisAnnulus diameterOutcomes of transcatheter aortic valve replacement in patients with chronic liver disease
Shah AM, Ogbara J, Herrmann HC, Fox Z, Kadakia M, Anwaruddin S, Bavaria JE, Desai ND, Jagasia D, Szeto WY, Li RH, Vallabhajosyula P, Giri J. Outcomes of transcatheter aortic valve replacement in patients with chronic liver disease. Catheterization And Cardiovascular Interventions 2015, 86: 888-894. PMID: 25963625, DOI: 10.1002/ccd.25994.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBioprosthesisBiopsyCardiac CatheterizationChronic DiseaseFeasibility StudiesFemaleFemoral ArteryHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansLiver DiseasesMaleMiddle AgedPatient SelectionRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsTranscatheter aortic valve replacementChronic liver diseaseValve Academic Research ConsortiumAcute kidney injuryAortic valve replacementLiver diseaseLate deathsKidney injuryValve replacementUnknown causeTransapical (TA) TAVRRole of TAVRTA TAVRSevere symptomatic aortic valve stenosisModerate chronic liver diseaseSymptomatic aortic valve stenosisAdvanced liver diseaseMajor bleeding complicationsNon-cardiac causesOutcomes of patientsTransient ischemic attackAcademic Research ConsortiumHigh-risk surgeryAortic valve stenosisLong-term followOverestimation of Paravalvular Leak With Edwards SAPIEN 3 Transcatheter Aortic Valve Replacement
Kobayashi T, Giri J, Vallabhajosyula P, Herrmann HC, Jagasia DH. Overestimation of Paravalvular Leak With Edwards SAPIEN 3 Transcatheter Aortic Valve Replacement. JACC Cardiovascular Interventions 2015, 8: e69-e71. PMID: 25946455, DOI: 10.1016/j.jcin.2014.11.027.Peer-Reviewed Original ResearchAged, 80 and overAortic ValveAortic Valve InsufficiencyAortic Valve StenosisAortographyCardiac CatheterizationDiagnostic ErrorsEchocardiography, Doppler, ColorFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansPredictive Value of TestsProsthesis DesignReproducibility of ResultsSeverity of Illness IndexTomography, X-Ray ComputedTreatment OutcomeOutcomes of Aortic Root Replacement After Previous Aortic Root Replacement: The “True” Redo Root
Jassar AS, Desai ND, Kobrin D, Pochettino A, Vallabhajosyula P, Milewski RK, McCarthy F, Maniaci J, Szeto WY, Bavaria JE. Outcomes of Aortic Root Replacement After Previous Aortic Root Replacement: The “True” Redo Root. The Annals Of Thoracic Surgery 2015, 99: 1601-1609. PMID: 25754965, DOI: 10.1016/j.athoracsur.2014.12.038.Peer-Reviewed Original ResearchConceptsAortic root replacementDe novo groupRedo root replacementRoot replacementNovo groupRedo groupPrevious aortic root replacementRedo aortic root replacementFirst-time sternotomyFull aortic root replacementLow perioperative morbidityStructural valve deteriorationRisk of complicationsPresence of infectionAortic reoperationHospital lengthLate deathsPerioperative deathsSternal infectionUnderwent reoperationMidterm survivalPerioperative morbidityRenal failureOverall mortalityValve deterioration
2014
Valve-sparing root reimplantation and leaflet repair in a bicuspid aortic valve: Comparison with the 3-cusp David procedure
Bavaria JE, Desai N, Szeto WY, Komlo C, Rhode T, Wallen T, Vallabhajosyula P. Valve-sparing root reimplantation and leaflet repair in a bicuspid aortic valve: Comparison with the 3-cusp David procedure. Journal Of Thoracic And Cardiovascular Surgery 2014, 149: s22-s28. PMID: 25500099, DOI: 10.1016/j.jtcvs.2014.10.103.Peer-Reviewed Original ResearchMeSH KeywordsAdultAortic AneurysmAortic ValveAortic Valve InsufficiencyBicuspid Aortic Valve DiseaseBlood Vessel Prosthesis ImplantationCardiac Surgical ProceduresDisease-Free SurvivalFemaleHeart Valve DiseasesHemodynamicsHumansKaplan-Meier EstimateMaleMiddle AgedReoperationReplantationRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeConceptsValve-sparing root reimplantationAortic valve patientsBAV patientsAI gradeMidterm outcomesAortic insufficiencyTransvalvular gradientValve patientsRoot reimplantationLeaflet repairEntire cohortBicuspid aortic valve patientsTricuspid aortic valve patientsAortic valve reoperationPrimary valve repairBicuspid aortic valveExcellent midterm outcomesActuarial freedomPostoperative freedomPostoperative mortalityValve reoperationBAV groupGroup patientsPacemaker requirementRetrospective reviewAortic and Mitral Valve Replacement Versus Transcatheter Aortic Valve Replacement in Propensity-Matched Patients
McCarthy FH, Desai ND, Herrmann HC, Kobrin D, Vallabhajosyula P, Fox Z, Menon R, Augoustides JG, Giri JS, Anwaruddin S, Li RH, Jagasia DH, Bavaria JE, Szeto WY. Aortic and Mitral Valve Replacement Versus Transcatheter Aortic Valve Replacement in Propensity-Matched Patients. The Annals Of Thoracic Surgery 2014, 98: 1267-1273. PMID: 25149054, DOI: 10.1016/j.athoracsur.2014.05.075.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic ValveFemaleHumansMaleMitral ValveMitral Valve InsufficiencyTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementAortic valve replacementSignificant mitral regurgitationMitral regurgitationValve replacementMVR groupTAVR groupMidterm survivalOpen aortic valve replacementEquivalent perioperative outcomesGreater mitral regurgitationPostoperative mitral regurgitationThoracic Surgeons scoreHigh-risk patientsPropensity-matched analysisPropensity-matched pairsPairs of patientsMitral valve repairMVR patientsPreoperative endocarditisPropensity matching techniquesTAVR patientsPerioperative outcomesEjection fractionSurgeons scoreAortic Valve Morphology Determines the Presentation and Surgical Approach to Acute Type A Aortic Dissection
Rylski B, Desai ND, Bavaria JE, Vallabhajosyula P, Moser W, Pochettino A, Szeto WY, Milewski RK. Aortic Valve Morphology Determines the Presentation and Surgical Approach to Acute Type A Aortic Dissection. The Annals Of Thoracic Surgery 2014, 97: 1991-1997. PMID: 24786861, DOI: 10.1016/j.athoracsur.2013.12.090.Peer-Reviewed Original ResearchConceptsTricuspid aortic valveBAV patientsAortic valve morphologyHospital mortalityAortic dissectionTAV patientsAcute Type A Aortic DissectionBicuspid aortic valve syndromeType A Aortic DissectionValve morphologyA Aortic DissectionSevere aortic insufficiencyTotal arch replacementAortic root replacementAortic root repairMedian followProximal reoperationAcute typeArch replacementCardiogenic shockAortic insufficiencyRoot replacementAortic diameterAorta diameterSurgical approachRoot Stabilization of the Repaired Bicuspid Aortic Valve: Subcommissural Annuloplasty Versus Root Reimplantation
Vallabhajosyula P, Komlo C, Szeto WY, Wallen TJ, Desai N, Bavaria JE. Root Stabilization of the Repaired Bicuspid Aortic Valve: Subcommissural Annuloplasty Versus Root Reimplantation. The Annals Of Thoracic Surgery 2014, 97: 1227-1234. PMID: 24418204, DOI: 10.1016/j.athoracsur.2013.10.071.Peer-Reviewed Original ResearchConceptsAortic insufficiencyReimplantation groupRoot reimplantationSubcommissural annuloplastyAnnular stabilizationRepair groupBicuspid aortic valve patientsPrimary valve repairSurgical reconstructive strategiesAortic valve patientsBicuspid aortic valveAortic root pathologyAortic reoperationValve mobilityPreoperative characteristicsOverall survivalPostoperative peakValve patientsPacemaker requirementRetrospective reviewReimplantation techniqueValve repairRoot pathologyAortic valveValve preservation