2023
Natural History and Intervention Thresholds for Ascending Thoracic Aortic Aneurysm—Not an Easy Nut to Crack
Zafar M, Elefteriades J. Natural History and Intervention Thresholds for Ascending Thoracic Aortic Aneurysm—Not an Easy Nut to Crack. JAMA Cardiology 2023, 8: 512-512. PMID: 36920367, DOI: 10.1001/jamacardio.2023.0153.Peer-Reviewed Original ResearchThe natural history of aortic root aneurysms
Ziganshin B, Kargin N, Zafar M, Elefteriades J. The natural history of aortic root aneurysms. Annals Of Cardiothoracic Surgery 2023, 12: 21324-21224. PMID: 37304695, PMCID: PMC10248916, DOI: 10.21037/acs-2023-avs1-20.Peer-Reviewed Original ResearchFate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University
Wu J, Zafar M, Liu Y, Chen J, Li Y, Ziganshin B, Ellauzi H, Mukherjee S, Rizzo J, Elefteriades J. Fate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University. European Heart Journal 2023, 44: 4579-4588. PMID: 36994934, DOI: 10.1093/eurheartj/ehad148.Peer-Reviewed Original ResearchConceptsAdverse aortic eventsThoracic aortic aneurysmAortic sizeAortic aneurysmCox regressionAortic growthRisk factorsSignificant independent risk factorsMultivariable Cox regressionIndependent risk factorCohort of patientsUnivariable Cox regressionSignificant protective factorAortic deathATAA patientsAortic eventsPrimary endpointSurgical interventionThree-decade experienceNatural historyYearly riskProtective factorsAneurysmsPatientsIntervention criteria
2019
Mechanics of the Thoracic Aortic Wall
Ziganshin B, Elefteriades J. Mechanics of the Thoracic Aortic Wall. 2019, 149-162. DOI: 10.1007/978-3-7091-4874-7_10.Peer-Reviewed Original ResearchTriggers of Aortic Dissection
Ziganshin B, Elefteriades J. Triggers of Aortic Dissection. 2019, 191-203. DOI: 10.1007/978-3-7091-4874-7_13.Peer-Reviewed Original Research
2017
PC084 Natural History and Management of Splanchnic Artery Aneurysms in a Single Tertiary Referral Center
Erben Y, Brownstein A, Rajaee S, Li Y, Rizzo J, Mojibian H, Ziganshin B, Elefteriades J. PC084 Natural History and Management of Splanchnic Artery Aneurysms in a Single Tertiary Referral Center. Journal Of Vascular Surgery 2017, 65: 161s-162s. DOI: 10.1016/j.jvs.2017.03.306.Peer-Reviewed Original ResearchMechanisms of Disease and Natural History
Ziganshin B, Elefteriades J. Mechanisms of Disease and Natural History. 2017, 19-43. DOI: 10.1007/978-3-319-15192-2_2.Peer-Reviewed Original ResearchAortic diseaseNatural historyEndovascular treatment optionsThoracic aortic diseaseClassic open surgeryDiseased aortic wallEvidence-based criteriaMechanisms of diseaseAortic pathologyAortic ruptureLethal complicationOpen surgeryProphylactic treatmentEndovascular interventionTreatment optionsIndividual patientsAortic wallPersonalized managementMechanisms of developmentDiseasePatientsSuch treatmentTreatmentCurrent understandingComplications
2011
Epidemiology and Natural History of Thoraco-Abdominal Aortic Aneurysms
Stein L, Elefteriades J. Epidemiology and Natural History of Thoraco-Abdominal Aortic Aneurysms. 2011, 25-32. DOI: 10.1007/978-88-470-1857-0_3.Peer-Reviewed Original ResearchThoracic aortic aneurysmAortic aneurysmThoraco-abdominal aortic aneurysmChronic obstructive pulmonary diseaseObstructive pulmonary diseaseSmooth muscle cellsTAAA rupturePulmonary diseaseTertiary centerAortic diameterTAAANatural historyAneurysm growthMuscle cellsOptimal timingAneurysmsPresent unique challengesRiskBetter identificationRupture increasesHypertensionSmokingPatientsDerangementUnique challenges
2008
Natural History: Evidence‐Based Indications for Operation
Elefteriades J. Natural History: Evidence‐Based Indications for Operation. 2008, 19-27. DOI: 10.1002/9781444300512.ch3.Peer-Reviewed Original ResearchAneurysmal thoracic aortaThoracic aorta ruptureThoracic aortaAortic eventsAortic ulcerIntramural hematomaProphylactic resectionMedical managementAneurysm patientsAorta ruptureAortic archLethal diseaseImpact of dissectionPatient sizeEvidence-based indicationsSize criteriaAortaNatural historyHematomaResectionUlcersPatientsAneurysmsThoracicDiseaseUnilateral diaphragm paralysis: etiology, impact, and natural history.
Elefteriades J, Singh M, Tang P, Siegel MD, Kenney B, Pandey A, Kopf GS. Unilateral diaphragm paralysis: etiology, impact, and natural history. The Journal Of Cardiovascular Surgery 2008, 49: 289-95. PMID: 18431352.Peer-Reviewed Original ResearchConceptsUnilateral diaphragm paralysisDiaphragm paralysisChronic obstructive pulmonary diseaseNatural historyBilateral diaphragm paralysisIntact phrenic nerveObstructive pulmonary diseaseSpirometric improvementClinical improvementExpiratory volumePulmonary infectionDiaphragm resectionLeft diaphragmOccasional patientPhrenic nervePulmonary diseaseSurgical explorationDiaphragm functionLower lobeVital capacityClinical recordsClinical spectrumMean durationNeurogenic atrophyBest therapy
1999
NATURAL HISTORY, PATHOGENESIS, AND ETIOLOGY OF THORACIC AORTIC ANEURYSMS AND DISSECTIONS
Coady M, Rizzo J, Goldstein L, Elefteriades J. NATURAL HISTORY, PATHOGENESIS, AND ETIOLOGY OF THORACIC AORTIC ANEURYSMS AND DISSECTIONS. Cardiology Clinics 1999, 17: 615-635. PMID: 10589336, DOI: 10.1016/s0733-8651(05)70105-3.Peer-Reviewed Original Research
1998
Penetrating ulcer of the thoracic aorta: What is it? How do we recognize it? How do we manage it?
Coady M, Rizzo J, Hammond G, Pierce J, Kopf G, Elefteriades J. Penetrating ulcer of the thoracic aorta: What is it? How do we recognize it? How do we manage it? Journal Of Vascular Surgery 1998, 27: 1006-1016. PMID: 9652462, DOI: 10.1016/s0741-5214(98)70003-5.Peer-Reviewed Original ResearchConceptsAortic dissectionOptimal treatmentThoracic aortaNatural historyType AType B aortic dissectionB aortic dissectionClassic aortic dissectionLarger aortic diametersAortic ulcerAtherosclerotic ulcerAortic ruptureClinical featuresInitial diagnosisInitial presentationIntraoperative findingsRetrospective reviewSurgical managementAortic diameterRadiologic signsTomographic scanPathology reportsUlcersPatientsAorta