2021
Characteristics of Randomized Clinical Trials in Surgery From 2008 to 2020
Robinson NB, Fremes S, Hameed I, Rahouma M, Weidenmann V, Demetres M, Morsi M, Soletti G, Di Franco A, Zenati MA, Raja SG, Moher D, Bakaeen F, Chikwe J, Bhatt DL, Kurlansky P, Girardi LN, Gaudino M. Characteristics of Randomized Clinical Trials in Surgery From 2008 to 2020. JAMA Network Open 2021, 4: e2114494. PMID: 34190996, PMCID: PMC8246313, DOI: 10.1001/jamanetworkopen.2021.14494.Peer-Reviewed Original ResearchConceptsMost trialsClinical eventsSurgical interventionSurgical RCTsClinical trialsSurgeon experienceMinor clinical eventsMore surgical interventionsReporting biasMajor clinical eventsRandomized clinical trialsRisk of biasMedian fragility indexMedian sample sizeLarge treatment effectsPrimary outcomeTRIAL REGISTRATIONControl armTrial characteristicsSurgical trialsHigh riskSuperiority designConcerns of biasPrimary analysisRCTs
2020
Valve-in-Valve Transcatheter Aortic Valve Replacement: A Review of Procedural Details, Safety, and Clinical Implications.
Hameed I, Ahmed A, Ullah N, Salemi A. Valve-in-Valve Transcatheter Aortic Valve Replacement: A Review of Procedural Details, Safety, and Clinical Implications. Cardiology In Review 2020, 28: 291-294. PMID: 32947481, DOI: 10.1097/crd.0000000000000318.Peer-Reviewed Original ResearchConceptsAortic valve replacementValve transcatheter aortic valve replacementTranscatheter aortic valve replacementVIV-TAVRValve replacementYounger patientsClinical implicationsSurgical aortic valve replacementProcedural detailsHigh-risk patientsBioprosthesis implantationCoronary obstructionSurgical interventionValvular thrombosisBioprosthetic valvesResidual gradientPatientsAnecdotal experienceTAVRPreferred procedureLong-term dataSafetyReinterventionThrombosisPrognosis