Barbora Salovska, PhD
she/her/hers
Associate Research Scientist in PharmacologyCards
About
Research
Publications
2026
Baseline cellular state dictates the molecular impact of KRAS mutant variants in pancreatic cancer cells.
Quiñones-Avilés Y, Salovska B, Markham CS, Di Y, Turk BE, Liu Y, Muzumdar MD. Baseline cellular state dictates the molecular impact of KRAS mutant variants in pancreatic cancer cells. BioRxiv 2026 PMID: 41959224, DOI: 10.64898/2026.03.10.710185.Peer-Reviewed Original Research
2025
Divergent proteome tolerance against gain and loss of chromosome arms
Di Y, Li W, Castellano J, Jin W, Modi J, Salovska B, Khosroabadi D, Hu W, Taylor A, Liu Y. Divergent proteome tolerance against gain and loss of chromosome arms. Molecular Cell 2025, 85: 4268-4278.e6. PMID: 41270725, PMCID: PMC12991381, DOI: 10.1016/j.molcel.2025.10.023.Peer-Reviewed Original ResearchThis study investigates how cells tolerate chromosome arm aneuploidy, showing distinct mechanisms where protein degradation compensates for gains, while synthesis upregulates proteins in losses to maintain balance.A robust multiplex-DIA workflow profiles protein turnover regulations associated with cisplatin resistance and aneuploidy
Salovska B, Li W, Bernhardt O, Germain P, Wang Q, Gandhi T, Reiter L, Liu Y. A robust multiplex-DIA workflow profiles protein turnover regulations associated with cisplatin resistance and aneuploidy. Nature Communications 2025, 16: 5034. PMID: 40447611, PMCID: PMC12125295, DOI: 10.1038/s41467-025-60319-x.Peer-Reviewed Original ResearchDetermination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Liblova Z, Maurencova D, Salovska B, Kratky M, Mracek T, Korandova Z, Pecinova A, Vasicova P, Rysanek D, Andera L, Fabrik I, Kupcik R, Kashmel P, Sultana P, Tambor V, Bartek J, Novak J, Vajrychova M, Hodny Z. Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence. Molecular Oncology 2025, 19: 2619-2647. PMID: 40288905, PMCID: PMC12420346, DOI: 10.1002/1878-0261.70039.Peer-Reviewed Original ResearchTurnover atlas of proteome and phosphoproteome across mouse tissues and brain regions
Li W, Dasgupta A, Yang K, Wang S, Hemandhar-Kumar N, Chepyala S, Yarbro J, Hu Z, Salovska B, Fornasiero E, Peng J, Liu Y. Turnover atlas of proteome and phosphoproteome across mouse tissues and brain regions. Cell 2025, 188: 2267-2287.e21. PMID: 40118046, PMCID: PMC12033170, DOI: 10.1016/j.cell.2025.02.021.Peer-Reviewed Original Research
2024
GABAA receptor π forms channels that stimulate ERK through a G-protein-dependent pathway
Wang Y, Zhang Y, Li W, Salovska B, Zhang J, Li T, Li H, Liu Y, Kaczmarek L, Pusztai L, Klein D. GABAA receptor π forms channels that stimulate ERK through a G-protein-dependent pathway. Molecular Cell 2024, 85: 166-176.e5. PMID: 39642883, PMCID: PMC11698630, DOI: 10.1016/j.molcel.2024.11.016.Peer-Reviewed Original ResearchThe RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization
Sztacho M, Červenka J, Šalovská B, Antiga L, Hoboth P, Hozák P. The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization. PLOS Genetics 2024, 20: e1011462. PMID: 39621780, PMCID: PMC11668513, DOI: 10.1371/journal.pgen.1011462.Peer-Reviewed Original ResearchBeyond glucose: The crucial role of redox signaling in β-cell metabolic adaptation
Holendová B, Šalovská B, Benáková Š, Plecitá-Hlavatá L. Beyond glucose: The crucial role of redox signaling in β-cell metabolic adaptation. Metabolism 2024, 161: 156027. PMID: 39260557, DOI: 10.1016/j.metabol.2024.156027.Peer-Reviewed Original ResearchPTMoreR-enabled cross-species PTM mapping and comparative phosphoproteomics across mammals
Wang S, Di Y, Yang Y, Salovska B, Li W, Hu L, Yin J, Shao W, Zhou D, Cheng J, Liu D, Yang H, Liu Y. PTMoreR-enabled cross-species PTM mapping and comparative phosphoproteomics across mammals. Cell Reports Methods 2024, 4: 100859. PMID: 39255793, PMCID: PMC11440062, DOI: 10.1016/j.crmeth.2024.100859.Peer-Reviewed Original Research
2023
Oncogene-like addiction to aneuploidy in human cancers
Girish V, Lakhani A, Thompson S, Scaduto C, Brown L, Hagenson R, Sausville E, Mendelson B, Kandikuppa P, Lukow D, Yuan M, Stevens E, Lee S, Schukken K, Akalu S, Vasudevan A, Zou C, Salovska B, Li W, Smith J, Taylor A, Martienssen R, Liu Y, Sun R, Sheltzer J. Oncogene-like addiction to aneuploidy in human cancers. Science 2023, 381: eadg4521-eadg4521. PMID: 37410869, PMCID: PMC10753973, DOI: 10.1126/science.adg4521.Peer-Reviewed Original Research
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West Haven, CT 06516