Katy Citrin
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Research
Publications
2016
Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6
Mouillesseaux KP, Wiley DS, Saunders LM, Wylie LA, Kushner EJ, Chong DC, Citrin KM, Barber AT, Park Y, Kim JD, Samsa LA, Kim J, Liu J, Jin SW, Bautch VL. Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6. Nature Communications 2016, 7: 13247. PMID: 27834400, PMCID: PMC5114582, DOI: 10.1038/ncomms13247.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBone morphogenetic proteinBMP responsivenessComplexities of BMPR-Smad phosphorylationSmad transcription factorsTarget gene expressionNotch-dependent regulationVessel growthBMP ligandsBMP inhibitorsTranscription factorsBMP2 ligandsMorphogenetic proteinsEndothelial cellsGene expressionSmad6 expressionLateral branchingNotch statusBlood vessel growthNuclear translocationBranch formationBind receptorsSmad6Vessel branchingCoordinated response