2019
Local Hemodynamic Conditions Associated with Focal Changes in the Intracranial Aneurysm Wall.
Cebral J, Detmer F, Chung B, Choque-Velasquez J, Rezai B, Lehto H, Tulamo R, Hernesniemi J, Niemela M, Yu A, Williamson R, Aziz K, Shakur S, Amin-Hanjani S, Charbel F, Tobe Y, Robertson A, Frösen J. Local Hemodynamic Conditions Associated with Focal Changes in the Intracranial Aneurysm Wall. American Journal Of Neuroradiology 2019, 40: 510-516. PMID: 30733253, PMCID: PMC6420361, DOI: 10.3174/ajnr.a5970.Peer-Reviewed Original ResearchMeSH KeywordsHemodynamicsHumansHydrodynamicsImaging, Three-DimensionalIntracranial AneurysmModels, CardiovascularRisk FactorsStress, MechanicalConceptsWall shear stressOscillatory shear indexGradient oscillatory numberOscillatory wall shear stressShear stressShear indexRelative residence timeWall shear stress gradientAverage wall shear stressFlow conditionsComputational fluid dynamics modelThin regionShear stress gradientLocal hemodynamicsFluid dynamics modelRecirculation zoneSwirling flowResidence timeStress gradientAneurysm hemodynamicsImpingement siteDynamic pressureAneurysm regionDynamic modelFlow stream
2018
Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location
Detmer F, Chung B, Jimenez C, Hamzei-Sichani F, Kallmes D, Putman C, Cebral J. Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location. Neuroradiology 2018, 61: 275-284. PMID: 30456458, PMCID: PMC6403015, DOI: 10.1007/s00234-018-2135-9.Peer-Reviewed Original ResearchConceptsHigh wall shear stressWall shear stressOscillatory shearAdverse hemodynamic environmentShear stressComplex flowHemodynamic environmentComplex shapesImage-based modelingIrregular shapeMorphologySidewall aneurysmsBifurcationFlowSidewallShearShapeAdverse hemodynamicsMiddle cerebral arteryInternal carotid artery