2023
The Clinical Utility of Antroduodenal Manometry in the Evaluation of Children with Upper Gastrointestinal Symptoms
Arbizu R, Trauernicht S, Pinillos S, Nurko S, Rodriguez L. The Clinical Utility of Antroduodenal Manometry in the Evaluation of Children with Upper Gastrointestinal Symptoms. Journal Of Pediatric Gastroenterology And Nutrition 2023, 77: 734-740. PMID: 37756372, DOI: 10.1097/mpg.0000000000003956.Peer-Reviewed Original ResearchConceptsGroup B symptomsUpper gastrointestinal symptomsIdiopathic etiologyB symptomsGastrointestinal symptomsPhase IIITreatment responseInitial successful responseIntestinal phase IIIOverall treatment responseSuccessful treatment responseSmall bowel motilityEvaluation of childrenSuccessful responseManometry measuresUGI symptomsAbdominal distentionAntroduodenal manometryPredominant symptomBowel motilityRetrospective reviewClinical findingsClinical utilitySymptomsEtiologyClinical Utility of Ileal Motility in Children With Defecation Disorders and Children With Chronic Intestinal Pseudo‐Obstruction
Colliard K, Nurko S, Flores A, Rodriguez L. Clinical Utility of Ileal Motility in Children With Defecation Disorders and Children With Chronic Intestinal Pseudo‐Obstruction. Journal Of Pediatric Gastroenterology And Nutrition 2023, 77: 327-331. PMID: 37229777, DOI: 10.1097/mpg.0000000000003841.Peer-Reviewed Original ResearchConceptsAntroduodenal manometryDefecation disordersPostprandial responseGroup BChronic Intestinal Pseudo-ObstructionIntestinal Pseudo-ObstructionNormal postprandial responseModerate agreementSmall bowel motilityLogistic regression analysisOstomy closurePseudo-ObstructionBowel motilityRetrospective reviewIleal motilityIndication groupGroup AClinical utilityYounger agePatientsMotility patternsPhase IIIMotor complexDisordersManometry
2016
Utility of Octreotide in Advancing Enteral Feeds in Children with Chronic Intestinal Pseudo-Obstruction
Ambartsumyan L, Flores A, Nurko S, Rodriguez L. Utility of Octreotide in Advancing Enteral Feeds in Children with Chronic Intestinal Pseudo-Obstruction. Pediatric Drugs 2016, 18: 387-392. PMID: 27520652, DOI: 10.1007/s40272-016-0189-x.Peer-Reviewed Original ResearchConceptsOctreotide responseEnteral toleranceAntroduodenal manometryChronic Intestinal Pseudo-ObstructionEfficacy of octreotideIntestinal phase IIIIntestinal Pseudo-ObstructionPresence of ileostomyTPN-dependent childrenTertiary care centerTotal parenteral nutritionMethodsThe study populationLimited effective therapiesHigher median increasePseudo-ObstructionParenteral nutritionEnteral feedsHigh morbidityProspective studyResultsA totalCare centerEffective therapyChallenging disorderAllergic reactionsStudy population
2013
Safety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children
Rodriguez L, Diaz J, Nurko S. Safety and Efficacy of Cyproheptadine for Treating Dyspeptic Symptoms in Children. The Journal Of Pediatrics 2013, 163: 261-267. PMID: 23419589, PMCID: PMC3661691, DOI: 10.1016/j.jpeds.2012.12.096.Peer-Reviewed Original ResearchConceptsEfficacy of cyproheptadineDyspeptic symptomsEarly vomitingSide effectsMultivariate analysisRetrospective open-label studyOpen-label studyUpper gastrointestinal symptomsPotent serotonin antagonistUse of cyproheptadineLack of responseLate vomitingAbdominal painGastrointestinal symptomsAntroduodenal manometryFunctional dyspepsiaNissen fundoplicationSerotonin antagonistsFirst therapyGastric emptyingFurther interventionTherapy responseVomitingCyproheptadineResponse rate