Mary Polan, MD, PhD, MPH
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Appointments
Contact Info
Obstetrics, Gynecology & Reproductive Sciences
PO Box 208063
New Haven, CT 06520-8063
United States
About
Titles
Professor of Obstetrics, Gynecology & Reproductive Sciences
Appointments
Obstetrics, Gynecology & Reproductive Sciences
ProfessorPrimary
Other Departments & Organizations
- Fertility Center
- In Vitro Fertilization Program
- Obstetrics, Gynecology & Reproductive Sciences
- Reproductive Endocrinology & Infertility
Education & Training
- MPH
- University of California at Berkeley (2001)
- Fellowship
- Yale University School of Medicine (1980)
- Fellowship
- Yale University School of Medicine (1979)
- Residency
- Yale University School of Medicine (1978)
- MD
- Yale University (1975)
- PhD
- Yale University (1970)
Board Certifications
Reproductive Endocrinology & Infertility
- Certification Organization
- AB of Obstetrics & Gynecology
- Original Certification Date
- 1984
Obstetrics & Gynecology
- Certification Organization
- AB of Obstetrics & Gynecology
- Original Certification Date
- 1980
Research
Research at a Glance
Publications Timeline
A big-picture view of Mary Polan's research output by year.
10Publications
520Citations
Publications
2001
Interleukin-1β Regulates Urokinase Plasminogen Activator (u-PA), u-PA Receptor, Soluble u-PA Receptor, and Plasminogen Activator Inhibitor-1 Messenger Ribonucleic Acid Expression in Cultured Human Endometrial Stromal Cells1
Chung H, Wen Y, Ahn J, Moon H, Polan M. Interleukin-1β Regulates Urokinase Plasminogen Activator (u-PA), u-PA Receptor, Soluble u-PA Receptor, and Plasminogen Activator Inhibitor-1 Messenger Ribonucleic Acid Expression in Cultured Human Endometrial Stromal Cells1. The Journal Of Clinical Endocrinology & Metabolism 2001, 86: 1332-1340. PMID: 11238529, DOI: 10.1210/jcem.86.3.7335.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsBinding, CompetitiveCells, CulturedCulture Media, ConditionedEndometriumEnzyme-Linked Immunosorbent AssayFemaleGene ExpressionHumansInterleukin-1Plasminogen Activator Inhibitor 1ProlactinReceptors, Cell SurfaceReceptors, Urokinase Plasminogen ActivatorRecombinant ProteinsReverse Transcriptase Polymerase Chain ReactionRNA, MessengerSolubilityStromal CellsUrokinase-Type Plasminogen ActivatorConceptsU-PA receptorMessenger ribonucleic acidIL-1betaPAI-1Urokinase plasminogen activatorU-PAInterleukin-1Confluent stromal cell culturesMessenger ribonucleic acid dataPlasminogen activatorCultured human endometrial stromal cellsU-PA mRNA expressionMeasured PAI-1Messenger ribonucleic acid expressionStromal cell decidualizationHuman endometrial stromal cellsIL-1beta antibodyRibonucleic acid expressionU-PAR expressionStromal cell culturesAnti-IL-1betaPlasminogen activator inhibitorLocal intercellular interactionsTreated with progesteronePlasminogen activation system
2000
Human Oviductal Gonadotropin-Releasing Hormone: Possible Implications in Fertilization, Early Embryonic Development, and Implantation1
Casañ E, Raga F, Bonilla-Musoles F, Polan M. Human Oviductal Gonadotropin-Releasing Hormone: Possible Implications in Fertilization, Early Embryonic Development, and Implantation1. The Journal Of Clinical Endocrinology & Metabolism 2000, 85: 1377-1381. PMID: 10770169, DOI: 10.1210/jcem.85.4.6503.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAdultEmbryo ImplantationEmbryonic and Fetal DevelopmentEndometriumEpitheliumFallopian TubesFemaleFertilizationFollicular PhaseGonadotropin-Releasing HormoneHumansImmunohistochemistryLuteal PhaseMenstrual CycleMiddle AgedPostmenopausePremenopauseReverse Transcriptase Polymerase Chain ReactionRNA, MessengerConceptsMessenger ribonucleic acidLuteal phaseProtein levelsHuman fallopian tubeEmbryonic developmentFallopian tubeTubal epitheliumPreimplantation embryosParacrine/autocrine roleMenstrual cycleAutocrine/paracrine regulatorParacrine mannerFertile patientsHuman oviductGnRH receptorEarly embryonic developmentGnRH immunostainingImmunohistochemical techniquesProtein expressionGnRHExtrahypothalamic GnRHRT-PCRReproductive lifeEarly embryosHuman fertility
1999
The Role of Gonadotropin-Releasing Hormone in Murine Preimplantation Embryonic Development*
Raga F, Casañ E, Kruessel J, Wen Y, Bonilla-Musoles F, Polan M. The Role of Gonadotropin-Releasing Hormone in Murine Preimplantation Embryonic Development*. Endocrinology 1999, 140: 3705-3712. DOI: 10.1210/en.140.8.3705.Peer-Reviewed Original ResearchCitationsConceptsPreimplantation murine embryosGnRH antagonistBlastocyst stageGnRH agonistMurine embryosPreimplantation development of embryosEffects of GnRH antagonistsEmbryo developmentConcentrations of GnRH agonistGnRH receptor messenger RNAHatched blastocyst stageReceptor messenger RNAEarly stages of placentationGnRH receptor mRNAPreimplantation embryonic developmentStages of placentationAntagonist in vitroGonadotropin-releasing hormonePreimplantation developmentReceptor mRNAGnRH analogsGnRH receptorMouse embryosPreimplantationDevelopment of embryos
1994
Embryonic implantation in mice is blocked by interleukin-1 receptor antagonist
Simón C, Frances A, Piquette G, Danasouri I, Zurawski G, Dang W, Polan M. Embryonic implantation in mice is blocked by interleukin-1 receptor antagonist. Endocrinology 1994, 134: 521-528. DOI: 10.1210/en.134.2.521.Peer-Reviewed Original ResearchCitationsAltmetricConceptsIL-1R tIRhIL-1raReceptor antagonistRecombinant human IL-1 receptor antagonistEmbryonic implantationHuman IL-1 receptor antagonistMouse embryosIL-1 receptor antagonistInterleukin-1 receptor antagonistEndometrial lumenal epitheliumInterleukin-1 receptor type IEndometrium in vivoIncreasing concentrations of rhIL-1raFisher's exact testReceptor type IPregnancy days 3Fibronectin-coated platesBlastocyst formationBlastocyst stagePeriimplantation periodMigration in vitroLumenal epitheliumIL-1raPregnancy failureEmbryonic attachment
1986
Laparoscopic use of the argon laser in nonendometriotic reproductive pelvic surgery.
Diamond M, DeCherney A, Polan M. Laparoscopic use of the argon laser in nonendometriotic reproductive pelvic surgery. The Journal Of Reproductive Medicine 1986, 31: 1011-3. PMID: 2949076.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsTreatment of endometriosisPelvic surgeryReproductive pelvic surgeryPelvic painArgon laserSubsequent pregnancy ratePelvic surgical proceduresPostoperative complicationsEndometriotic implantsPreoperative diagnosisShort followInfertility proceduresLesion absorptionComplete resolutionLaparoscopic surgeryUterosacral ligamentsPregnancy rateSurgical proceduresSurgeryLaparoscopic usePainPatientsLaser efficacySuch pigmentationEndometriosis
1984
Fallopian tubal patency assessed by ultrasound following fluid injection. Work in progress.
Richman T, Viscomi G, deCherney A, Polan M, Alcebo L. Fallopian tubal patency assessed by ultrasound following fluid injection. Work in progress. Radiology 1984, 152: 507-10. PMID: 6539931, DOI: 10.1148/radiology.152.2.6539931.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsTubal patencyFallopian tubal patencyConventional hysterosalpingogramInfertile womenBilateral occlusionAbility of ultrasoundTubal occlusionFallopian tubeContrast materialPatencyUnnecessary exposureFree fluidFemale pelvisUltrasoundUltrasound techniqueOcclusionHysterosalpingogramSonosalpingographyEditors' Formulation
DeCherney A, Polan M. Editors' Formulation. Seminars In Reproductive Medicine 1984, 2: 220-221. DOI: 10.1055/s-2007-1023847.Peer-Reviewed Original ResearchEvaluation and management of habitual abortion.
DeCherney A, Polan M. Evaluation and management of habitual abortion. British Journal Of Hospital Medicine 1984, 31: 261-2, 266-8. PMID: 6232971.Peer-Reviewed Original ResearchCitations
1983
Hysteroscopic management of intrauterine lesions and intractable uterine bleeding.
DeCherney A, Polan M. Hysteroscopic management of intrauterine lesions and intractable uterine bleeding. Obstetrics And Gynecology 1983, 61: 392-7. PMID: 6823383.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsIntractable uterine bleedingUterine bleedingIntrauterine lesionsYale-New Haven HospitalMüllerian fusion defectsLong-term complicationsMajor surgical interventionUterine anomaliesAbdominal surgeryHysteroscopic managementSurgical managementSubmucous myomasSurgical interventionTranscervical approachConcomitant laparoscopyMüllerian defectsPatientsBleedingWomenLesionsSurgical useMyomasComplicationsHemorrhageMensesAbdominal myomectomy and subsequent fertility.
Berkeley A, DeCherney A, Polan M. Abdominal myomectomy and subsequent fertility. Journal Of The American College Of Surgeons 1983, 156: 319-22. PMID: 6828976.Peer-Reviewed Original ResearchCitationsMeSH Keywords and Concepts
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News
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- April 30, 2017
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- July 15, 2003
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- April 15, 2000
Eight decades of the Yale System
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Obstetrics, Gynecology & Reproductive Sciences
PO Box 208063
New Haven, CT 06520-8063
United States
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125A Kings Highway North
Westport, CT 06880
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