2024
Bone marrow mesenchymal stem cell-derived exosomes shuttle microRNAs to endometrial stromal fibroblasts that promote tissue proliferation /regeneration/ and inhibit differentiation
Bonavina G, Mamillapalli R, Krikun G, Zhou Y, Gawde N, Taylor H. Bone marrow mesenchymal stem cell-derived exosomes shuttle microRNAs to endometrial stromal fibroblasts that promote tissue proliferation /regeneration/ and inhibit differentiation. Stem Cell Research & Therapy 2024, 15: 129. PMID: 38693588, PMCID: PMC11064399, DOI: 10.1186/s13287-024-03716-1.Peer-Reviewed Original ResearchConceptsMiR-100-5pMiR-100MiR-21Transmission electron microscopyMiR-143MiR-143-3pMiR-21-5pEndometrial stromal fibroblastsStromal fibroblastsMicroRNAsExtracellular vesiclesElectron microscopyCell-free regenerative therapyNanoparticle tracking analysisMiRNAsBone marrow mesenchymal stem cell-derived exosomesBone marrow-derived stem cellsMesenchymal stem cell-derived exosomesStem cell-derived exosomesDelivery of microRNAsMarrow-derived stem cellsAssociated with several signaling pathwaysMediators of tissue repairMethodsExtracellular vesiclesUnpaired t-test
2007
Contribution of Bone Marrow‐Derived Stem Cells to Endometrium and Endometriosis
Du H, Taylor HS. Contribution of Bone Marrow‐Derived Stem Cells to Endometrium and Endometriosis. Stem Cells 2007, 25: 2082-2086. PMID: 17464086, DOI: 10.1634/stemcells.2006-0828.Peer-Reviewed Original ResearchConceptsBone marrow-derived cellsDonor-derived bone marrow cellsLacZ transgenic miceBone marrow cellsUterine endometriumBone marrowEndometrial cellsPeritoneal cavityTransgenic miceMarrow cellsStem cellsEctopic endometrial implantationNormal endometrial physiologyBone marrow-derived stem cellsBone marrow transplantationMale bone marrowMarrow-derived cellsMarrow-derived stem cellsHuman uterine endometriumEndometrial implantationMesenchymal stem cell originStem cell originMarrow transplantationEndometrial physiologyExperimental endometriosis