2012
FKBP4 is regulated by HOXA10 during decidualization and in endometriosis
Yang H, Zhou Y, Edelshain B, Schatz F, Lockwood CJ, Taylor HS. FKBP4 is regulated by HOXA10 during decidualization and in endometriosis. Reproduction 2012, 143: 531-538. PMID: 22279148, DOI: 10.1530/rep-11-0438.Peer-Reviewed Original ResearchConceptsHuman endometrial stromal cellsFKBP4 expressionFKBP5 expressionTreatment of hESCCultured human endometrial stromal cellsIGFBP1 expressionEndometrium of womenProtein levelsEndometrial stromal cellsLate proliferative phaseHOXA10 knockdownHOXA10 regulationImpaired decidualizationFertile womenEutopic endometriumMenstrual cycleSecretory phaseEndometriosisDecidualizationHOXA10 expressionProliferative phaseStromal cellsMRNA expressionFKBP5FKBP4
2011
MicroRNA 135 Regulates HOXA10 Expression in Endometriosis
Petracco R, Grechukhina O, Popkhadze S, Massasa E, Zhou Y, Taylor HS. MicroRNA 135 Regulates HOXA10 Expression in Endometriosis. The Journal Of Clinical Endocrinology & Metabolism 2011, 96: e1925-e1933. PMID: 21956427, PMCID: PMC3232619, DOI: 10.1210/jc.2011-1231.Peer-Reviewed Original ResearchConceptsEndometrium of womenHOXA10 expressionHOXA10 regulationB expressionProliferative phaseEndometrial stromal cellsUniversity Medical CenterRegulation of HOXA10Time of ovulationMicroRNA-135Endometrial biopsyEndometrial receptivityMCF-7 cellsEndometrial samplesMenstrual cycleLuteal phaseMedical CenterSex steroidsStudy interventionEndometriosisSecretory phaseHOXA10 mRNAMicroRNA-135aStromal cellsEndometriumCigarette Smoke Increases Progesterone Receptor and Homeobox A10 Expression in Human Endometrium and Endometrial Cells: A Potential Role in the Decreased Prevalence of Endometrial Pathology in Smokers1
Zhou Y, Jorgensen EM, Gan Y, Taylor HS. Cigarette Smoke Increases Progesterone Receptor and Homeobox A10 Expression in Human Endometrium and Endometrial Cells: A Potential Role in the Decreased Prevalence of Endometrial Pathology in Smokers1. Biology Of Reproduction 2011, 84: 1242-1247. PMID: 21325691, PMCID: PMC3099588, DOI: 10.1095/biolreprod.110.087494.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCells, CulturedEndometriumFemaleGene Expression RegulationHomeobox A10 ProteinsHomeodomain ProteinsHumansMiceReceptors, ProgesteroneSmokeTobaccoConceptsProgesterone receptorCigarette smokeRate of endometriosisEffect of smokingCigarette smoke extractEndometrial stromal cellsExpression of HOXA10Poor health outcomesEndometrial cancerEndometrial pathologyEndometrial diseaseCigarette smokingDecreased incidenceOvarian alterationsDecreased prevalenceEndometrial tumorsEndometrial differentiationEndometrial cellsHuman endometriumSmoke extractProtective effectHomeobox A10Health outcomesHomeobox A10 expressionSmoking
2010
Bisphenol‐A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response
Bromer JG, Zhou Y, Taylor MB, Doherty L, Taylor HS. Bisphenol‐A exposure in utero leads to epigenetic alterations in the developmental programming of uterine estrogen response. The FASEB Journal 2010, 24: 2273-2280. PMID: 20181937, PMCID: PMC3230522, DOI: 10.1096/fj.09-140533.Peer-Reviewed Original ResearchConceptsEpigenetic alterationsCytosine-guanine dinucleotides (CpGs) methylationUtero BPA exposureHomeobox gene HOXA10Developmental programmingDiminished methylationChromatin immunoprecipitationBisulfite sequencingEpigenetic mechanismsDNA methylationPromoter sequencesBPA exposureMethylation profilesExpression patternsGene expressionUterine organogenesisUterine estrogen responsesMethylationNovel mechanismGeneral mechanismPregnant CD-1 miceProtein expressionCD-1 miceHOXA10Expression