Qingji Xu, PhD
he/him/his
Postdoctoral AssociateDownloadHi-Res Photo
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Titles
Postdoctoral Associate
Appointments
Education & Training
- PhD
- Institute of Biophysics, Chinese Academy of Sciences, Cell Biology (2023)
- BS
- College of Life Sciences, Jilin University, Biopharmaceutical Engineering (2017)
Research
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Overview
Medical Research Interests
Biomarkers, Tumor; Gene Expression Regulation, Neoplastic; Immunotherapy; Melanoma; Molecular Targeted Therapy
ORCID
0000-0002-9524-1848Yan Lab@Yale
Cancer Epigenetics and Stem Cell Biology
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Publications
2024
Setdb1 Loss Induces Type I Interferons and Immune Clearance of Melanoma.
McGeary M, Damsky W, Daniels A, Lang S, Xu Q, Song E, Huet-Calderwood C, Lou H, Paradkar S, Micevic G, Kaech S, Calderwood D, Turk B, Yan Q, Iwasaki A, Bosenberg M. Setdb1 Loss Induces Type I Interferons and Immune Clearance of Melanoma. Cancer Immunology Research 2024, 13: 245-257. PMID: 39589394, DOI: 10.1158/2326-6066.cir-23-0514.Peer-Reviewed Original ResearchCitationsAltmetric
2023
CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway
Chen J, Xu Q, Liu D, Li X, Guo M, Chen X, Liao J, Lei R, Li W, Huang H, Saw P, Song E, Yan X, Nie Y. CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway. Cancer Communications 2023, 43: 1244-1266. PMID: 37856423, PMCID: PMC10631482, DOI: 10.1002/cac2.12495.Peer-Reviewed Original ResearchCitationsAltmetric
2021
Structure basis for AA98 inhibition on the activation of endothelial cells mediated by CD146
Chen X, Yan H, Liu D, Xu Q, Duan H, Feng J, Yan X, Xie C. Structure basis for AA98 inhibition on the activation of endothelial cells mediated by CD146. IScience 2021, 24: 102417. PMID: 33997697, PMCID: PMC8093899, DOI: 10.1016/j.isci.2021.102417.Peer-Reviewed Original ResearchCitationsAltmetric
2020
Review and prospect of CD146 research
DUAN H, XIONG C, Lin J, XU Q, LIU J, MA X, WANG D, XIANG J, HE Z, Jing F, YAN X. Review and prospect of CD146 research. Scientia Sinica Vitae 2020, 50: 1339-1387. DOI: 10.1360/ssv-2020-0238.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsCD146, from a melanoma cell adhesion molecule to a signaling receptor
Wang Z, Xu Q, Zhang N, Du X, Xu G, Yan X. CD146, from a melanoma cell adhesion molecule to a signaling receptor. Signal Transduction And Targeted Therapy 2020, 5: 148. PMID: 32782280, PMCID: PMC7421905, DOI: 10.1038/s41392-020-00259-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetric
2018
CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-β signaling-induced epithelial-mesenchymal transition
Ma Y, Zhang H, Xiong C, Liu Z, Xu Q, Feng J, Zhang J, Wang Z, Yan X. CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-β signaling-induced epithelial-mesenchymal transition. Cancer Letters 2018, 430: 201-214. PMID: 29777784, DOI: 10.1016/j.canlet.2018.05.016.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsAnimalsCadherinsCD146 AntigenCell Line, TumorCell MovementEpithelial-Mesenchymal TransitionFemaleFibroblastsGene Knockout TechniquesHumansMiceMiddle AgedNuclear ProteinsOvarian NeoplasmsOvarySignal TransductionSTAT3 Transcription FactorSurvival RateTransforming Growth Factor betaTwist-Related Protein 1
2016
Design of hydrogels of 5-hydroxymethyl tolterodine and their studies on pharmacokinetics, pharmacodynamics and transdermal mechanism
Liu W, Teng L, Yu K, Sun X, Fan C, Long C, Liu N, Li S, Wu B, Xu Q, Sun F, Li Y. Design of hydrogels of 5-hydroxymethyl tolterodine and their studies on pharmacokinetics, pharmacodynamics and transdermal mechanism. European Journal Of Pharmaceutical Sciences 2016, 96: 530-541. PMID: 27789373, DOI: 10.1016/j.ejps.2016.10.024.Peer-Reviewed Original ResearchCitations
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Lauder Hall
Lab
310 Cedar Street, Fl 3, Rm 304
New Haven, CT 06510