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In honor of National Cancer Research Month, Dr. Qin Yan describes his research in epigenetics and two recent studies he is proudest of, both of which are pushing the field of epigenetics in cancer research forward.

Yale Cancer Center faculty and trainees joined 22,000 cancer researchers from around the world to share the latest advances in cancer science and medicine earlier this week in Chicago for the 116th American Association for Cancer Research (AACR) annual meeting. Dr. Patricia LoRusso, Amy and Joseph Perella Professor of Medicine at Yale Cancer Center and AACR President for 2024-25, shared her global view on cancer. “Cancer is a global disease—it spares no continent, no country. And each patient that gets the disease deserves treatment.”

Formerly called the Conclave Awards, the 2025 Spring Yale Cancer Center awards honored research, clinical expertise, and support staff at the Hotel Marcel, New Haven on April 1, 2025.

A new study from scientists at Yale School of Medicine has identified N-acetyltransferase 10 (NAT10), an enzyme highly expressed in brain metastasis, as a driver of brain metastasis. NAT10 primarily functions by adding acetyl groups to RNA molecules, regulating their function, stability or translation.

Institutional support, federal funding, philanthropy and grants are the support that make cancer research possible.

Qin Yan, PhD, Professor of Pathology, receives Outstanding Investigator Award from the American Society of Investigative Pathology.

A research team co-led by Dr. Katerina Politi found how mSWI/SNF complexes mediate resistance of lung adenocarcinomas to osimertinib and other tyrosine kinase inhibitors.

A new study from Yale Cancer Center scientists has identified the chromatin regulator WDR5 as a possible new drug target in triple negative breast cancer.