Bio Haven: How Yale and New Haven are building a future together
New Haven’s biotech community has seen fits and starts, but today it is achieving critical mass. Upwards of 50 biotech and medical device companies employ more than 5,000 people in greater New Haven. Yale School of Medicine has been instrumental in the communty's growth.
How fruit fly geneticist Tian Xu is transforming the mouse into a genetics workhorse to reveal the causes of human disease
Sitting in a standard-issue clear plastic cage among hundreds of other white laboratory mice, the piggyBac mouse looks absolutely ordinary, not a bit like an animal poised to turn human genetics research on its head. But when Tian Xu, Ph.D., professor of genetics, switches on an ultraviolet lamp, the mouse emits a faint pink glow—an aura that holds the secret of its transformative power.
Study: People Who Regularly Drink Alcohol Could Be More Prone to Internet, Gaming, and Exercise Addiction
An international research team with members that include Yale scientist Marc Potenza, MD, PhD, have identified several genes and their variants that trigger both substance use and other potentially addictive behaviors.
Epidemiologic and Genetic Associations of Endometriosis With Depression, Anxiety, and Eating Disorders
A Yale-led study published in JAMA Network Open is the first large-scale analysis to investigate phenotypic and genetic factors contributing to the psychiatric comorbidity of endometriosis, a complex gynecologic disease.
Cannabis Use is Associated With Low Plasma Endocannabinoid Anandamide in Individuals With Psychosis
Anahita Bassir Nia, MD, assistant professor of psychiatry, and Claire Gibson, MD, fourth-year resident, are lead and contributing authors, respectively, of a study in Journal of Psychopharmacology reporting that among individuals with psychosis, cannabis use is associated with lower levels of Anandamide, one of the main endogenous cannabinoids. This is the first published study on the peripheral levels of endocannabinoids in individuals with psychosis.Source: Journal of Psychopharmacology
Can Neuroimaging Reveal the Roots of Psychiatric Disorders? Not Just Yet
Neuroimaging technology has been shown to hold great promise in helping clinicians link specific symptoms of mental health disorders to abnormal patterns of brain activity. But a new Yale-led study shows there are still kinks to be ironed out before doctors can translate images of the brain to psychiatric disorders such as post-traumatic stress disorder (PTSD).Source: Yale News
Confronting Racially Exclusionary Practices in the Acquisition and Analyses of Neuroimaging Data
A new paper by Yale School of Medicine researchers challenges scientists in the global neuroscience community to create a more diverse representation of study participants through improved recruitment and enhanced methodological and analysis practices.
Newly Identified Neuromarker Reveals Clues About Drug and Food Craving
Hedy Kober, PhD, associate professor of psychiatry and psychology, is senior author of a study published in Nature Neuroscience that uncovered a pattern of brain activity that predicts drug and food craving, a potentially valuable biomarker for addiction.Source: Yale News
Krystal Research Published in The Lancet
Data from an early phase clinical trial of a drug being developed for adults living with schizophrenia was published December 15 in The Lancet. John H. Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and professor of psychiatry, of neuroscience, and of psychology, and chair of the Yale Department of Psychiatry, is first author of the study of the drug emraclidine, developed by Cerevel Therapeutics.
Yale Department of Internal Medicine Celebrates Top Female Scientists
Last month, Research.com published the Best Female Scientists in 2022. The results were based on a ranking system which measures the impact of a researcher’s publications by combining the number of papers they have published and how often they are cited by other papers. 623 U.S.-based researchers appeared in list with three women representing the Yale Department of Internal Medicine.
Yale Study Seeks to Understand Neurobiology Underlying Bipolar Disorder Vs. Major Depressive Disorder
Yale scientists, including Sophie Holmes, PhD; Ruth Asch, PhD; and Irina Esterlis, PhD, used positron emission tomography to understand the neurobiology underlying bipolar disorder versus major depressive disorder. The findings were published in Biological Psychiatry.Source: Biological Psychiatry
Collaboration on NIH grant between Sullivan, Nez Henderson will create program to help Indigenous women experiencing domestic violence quit smoking
Tami Sullivan, PhD, associate professor of psychiatry at Yale School of Medicine, and Patricia Nez Henderson, MD, MPH, vice president for the Black Hills Center for American Indian Health (BHCAIH) and the first Indigenous woman to graduate from Yale School of Medicine, have been awarded a grant from the National Institutes of Health (NIH) to pilot a mindfulness-based, culturally-tailored smoking cessation intervention for Indigenous women who experience intimate partner violence (IPV).
A Randomized Clinical Trial to Evaluate an Atrial Fibrillation Stroke Prevention Shared Decision‐Making Pathway
Oral anticoagulation (OAC) reduces stroke and disability in atrial fibrillation (AF) but is underutilized. Researchers, including Julio Nunes, MD, first-year resident, evaluated the effects of a novel patient‐clinician shared decision‐making (SDM) tool in reducing OAC patient's decisional conflict as compared to usual care.Source: Journal of the American Heart Association
Does Street Outreach Engage Its Intended Target Population? Clinical Experience in the Veteran’s Health Administration Homeless Service Programs
Emma Lo, MD; Jack Tsai, PhD; Elina Stefanovics, PhD; and Robert Rosenheck, MD, are co-authors of a paper in Psychiatric Quarterly that found veterans engaged through clinical street outreach programs reported substantially more days of unsheltered homelessness than a clinic-referred group of veterans.Source: Psychiatric Quarterly