The goal of our laboratory is to uncover novel treatments for hard-to-treat cancers. Our approach is to understand how defects in a tumor's ability to repair its DNA and maintain its energy supply result in vulnerabilities that can be exploited for therapeutic gain. In addition, our lab seeks to better understand how targeting DNA repair and metabolic pathways impacts the immune response against tumors, making them more sensitive to immunotherapies.
Vasquez Lab
About Us
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Our translational and multidisciplinary laboratory is at the intersection of DNA repair, tumor metabolism, and cancer immunology. We strive to discover treatment approaches that exploit DNA repair and metabolic pathways to selectively target solid tumors while also sensitizing them to immunotherapy.
Principal Investigator
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Juan Vasquez, MD
Assistant Professor of Pediatrics (Hematology/Oncology)