2021
Effectiveness of spatially targeted interventions for control of HIV, tuberculosis, leprosy and malaria: a systematic review
Khundi M, Carpenter JR, Nliwasa M, Cohen T, Corbett EL, MacPherson P. Effectiveness of spatially targeted interventions for control of HIV, tuberculosis, leprosy and malaria: a systematic review. BMJ Open 2021, 11: e044715. PMID: 34257091, PMCID: PMC8278879, DOI: 10.1136/bmjopen-2020-044715.Peer-Reviewed Original ResearchConceptsSystematic reviewCommunity public health interventionsGlobal elimination targetsCommunity-based screeningControl of HIVMass drug administrationPublic health interventionsData extraction toolIndoor residual sprayingEvidence of effectWeb of ScienceCochrane DatabaseElimination targetsCommunity screeningInclusion criteriaDrug AdministrationHIVComplex interventionsHealth interventionsInfectious diseasesTuberculosisIntensive interventionIntervention impactMalaria studiesResidual spraying
2020
Genomic variant-identification methods may alter Mycobacterium tuberculosis transmission inferences
Walter KS, Colijn C, Cohen T, Mathema B, Liu Q, Bowers J, Engelthaler DM, Narechania A, Lemmer D, Croda J, Andrews JR. Genomic variant-identification methods may alter Mycobacterium tuberculosis transmission inferences. Microbial Genomics 2020, 6: mgen000418. PMID: 32735210, PMCID: PMC7641424, DOI: 10.1099/mgen.0.000418.Peer-Reviewed Original Research
2018
Where is tuberculosis transmission happening? Insights from the literature, new tools to study transmission and implications for the elimination of tuberculosis
Auld SC, Shah NS, Cohen T, Martinson NA, Gandhi NR. Where is tuberculosis transmission happening? Insights from the literature, new tools to study transmission and implications for the elimination of tuberculosis. Respirology 2018, 23: 807-817. PMID: 29869818, PMCID: PMC6281783, DOI: 10.1111/resp.13333.Peer-Reviewed Original ResearchTB control activitiesEvidence-based public health interventionsElimination of tuberculosisBurden of tuberculosisInfection control programCommunity-based transmissionPublic health interventionsCommunity-based settingsUnderstanding of transmissionMiddle-income countriesContact investigationTB incidenceTB transmissionTB epidemicTB strainsTuberculosis transmissionPatterns of transmissionHealth interventionsMeaningful improvementsNew casesMolecular epidemiologyTuberculosisControl activitiesOngoing transmissionVentilation studies
2014
Prospective evaluation of a complex public health intervention: lessons from an initial and follow-up cross-sectional survey of the tuberculosis strain typing service in England
Mears J, Abubakar I, Crisp D, Maguire H, Innes JA, Lilley M, Lord J, Cohen T, Borgdorff MW, Vynnycky E, McHugh TD, Sonnenberg P. Prospective evaluation of a complex public health intervention: lessons from an initial and follow-up cross-sectional survey of the tuberculosis strain typing service in England. BMC Public Health 2014, 14: 1023. PMID: 25273511, PMCID: PMC4194411, DOI: 10.1186/1471-2458-14-1023.Peer-Reviewed Original ResearchMeSH KeywordsAttitude of Health PersonnelBacterial Typing TechniquesClinical CompetenceCost-Benefit AnalysisCross-Sectional StudiesEnglandFemaleFollow-Up StudiesHealth ServicesHumansMaleMolecular EpidemiologyMycobacteriumPopulation SurveillanceProgram EvaluationProspective StudiesPublic HealthSurveys and QuestionnairesTuberculosisConceptsPublic health interventionsComplex public health interventionsCross-sectional surveyHealth interventionsNational public health interventionsStrain typingPublic health staffRepeated cross-sectional surveySignificant increaseMIRU-VNTR typingProportion of respondentsTB patientsSelf-rated knowledgeTB controlProspective evaluationMixed-method evaluationHealth staffProspective identificationMajority of respondentsService users' perceptionsMethodsAn onlineInterventionTypingFuture evaluationProfessional groups
2013
Evaluation of the Tuberculosis Strain Typing Service (TB-STS) in England
Mears J, Vynnycky E, Lord J, Borgdorff M, Cohen T, Abubakar I, Sonnenberg P, group O. Evaluation of the Tuberculosis Strain Typing Service (TB-STS) in England. The Lancet 2013, 382: s73. DOI: 10.1016/s0140-6736(13)62498-8.Peer-Reviewed Original ResearchTuberculosis incidenceProportion of infectionsDiagnostic delayBase-case assumptionsLatent infectionPulmonary tuberculosis casesTuberculosis control effortsHigh-incidence settingsMycobacterium tuberculosis isolatesCluster investigationsTuberculosis notification ratesPost-implementation dataComplex public health interventionsPopulation-level interventionsPublic health interventionsMIRU-VNTR typingTuberculosis infectionTuberculosis casesPreventive treatmentPublic health outcomesNotification ratesTuberculosis isolatesSenior Research FellowshipDeterministic compartmental modelProportion of individuals
2011
Generalized Markov models of infectious disease spread: A novel framework for developing dynamic health policies
Yaesoubi R, Cohen T. Generalized Markov models of infectious disease spread: A novel framework for developing dynamic health policies. European Journal Of Operational Research 2011, 215: 679-687. PMID: 21966083, PMCID: PMC3182455, DOI: 10.1016/j.ejor.2011.07.016.Peer-Reviewed Original ResearchMathematical modelDynamic optimization techniquesGeneralized Markov modelClass of modelsState space sizeMarkov chain modelInfectious disease spreadOptimization techniquesDiscrete-time Markov chain modelComputation timeHost transmission dynamicsChain modelInfectious diseasesSpace sizeHost natural historyMarkov modelHealth policyPrevious modelsPublic health interventionsTransmission dynamicsClassModelReal-time selectionDisease spreadHealth interventions
2010
The Impact of Realistic Age Structure in Simple Models of Tuberculosis Transmission
Brooks-Pollock E, Cohen T, Murray M. The Impact of Realistic Age Structure in Simple Models of Tuberculosis Transmission. PLOS ONE 2010, 5: e8479. PMID: 20062531, PMCID: PMC2797602, DOI: 10.1371/journal.pone.0008479.Peer-Reviewed Original ResearchConceptsSimple modelReproductive ratioRealistic age structureSteady-state dynamicsBasic reproductive ratioMathematical descriptionMathematical modelParameter estimationRepresentative of modelsAnalytic argumentsInterpretation of modelsTuberculosis transmissionModelling assumptionsTB modelControl interventionsTB natural historyChronic infectious diseaseDisease dynamicsPublic health interventionsRealistic distributionExponential lifetimesAsymptomatic latent infectionIndividual-based modelPrevalence of infectionActive disease