2022
LGG-52. Volumetry-based response characterization of recurrent pediatric low-grade gliomas in PNOC clinical Neuro-oncology trials
von Reppert M, Lin M, Bousabarah K, Familiar A, Velasco R, Waanders A, Vossough A, Haddock A, Nicolaides T, Swanson K, Kazerooni A, Kline C, Nabavizadeh A, Haas-Kogan D, Prados M, Rubin J, Mueller S, Aboian M. LGG-52. Volumetry-based response characterization of recurrent pediatric low-grade gliomas in PNOC clinical Neuro-oncology trials. Neuro-Oncology 2022, 24: i100-i100. PMCID: PMC9165161, DOI: 10.1093/neuonc/noac079.364.Peer-Reviewed Original ResearchPediatric low-grade gliomasClinical trialsLow-grade gliomasRANO criteriaResponse assessmentNeuro-oncology trialsSingle-agent everolimusTreatment response analysisCentral imaging reviewInter-reader agreementClinical outcomesTumor sizeImaging reviewCystic componentTreatment responseTumor volumeTrue tumor volumeNovel treatmentsVolumetric assessmentTrial outcomesVolumetric measuresEntire tumorOverall discordanceNeuroradiology practiceTrials
2015
3D quantitative assessment of response to fractionated stereotactic radiotherapy and single-session stereotactic radiosurgery of vestibular schwannoma
Schneider T, Chapiro J, Lin M, Geschwind JF, Kleinberg L, Rigamonti D, Jusué-Torres I, Marciscano AE, Yousem DM. 3D quantitative assessment of response to fractionated stereotactic radiotherapy and single-session stereotactic radiosurgery of vestibular schwannoma. European Radiology 2015, 26: 849-857. PMID: 26139318, PMCID: PMC4698362, DOI: 10.1007/s00330-015-3895-9.Peer-Reviewed Original ResearchConceptsSingle-session stereotactic radiosurgeryTotal tumor volumeSignificant tumor shrinkageVestibular schwannomaTumor shrinkageStereotactic radiotherapyTumor volumeRadiation therapyStereotactic radiosurgeryT1-weighted contrast-enhanced MRISubsequent microsurgical resectionTumor-related symptomsSporadic vestibular schwannomaContrast-enhanced MRIFSRT groupRadiological progressionMicrosurgical resectionClinical outcomesSRS groupRetrospective analysisResponse assessmentPatientsVolumetric assessmentFSRTSchwannoma