Longer-Term Outcomes Following Mechanical Thrombectomy for Intermediate- and High-Risk Pulmonary Embolism: 6-Month FLASH Registry Results
Khandhar S, Jaber W, Bunte M, Cho K, Weinberg M, Mina B, Stegman B, Pollak J, Khosla A, Elmasri F, Zlotnick D, Brancheau D, Koenig G, Bisharat M, Li J, Toma C, Investigators F. Longer-Term Outcomes Following Mechanical Thrombectomy for Intermediate- and High-Risk Pulmonary Embolism: 6-Month FLASH Registry Results. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 2: 101000. PMID: 39131661, PMCID: PMC11307656, DOI: 10.1016/j.jscai.2023.101000.Peer-Reviewed Original ResearchChronic thromboembolic pulmonary hypertensionChronic thromboembolic diseaseRisk pulmonary embolismThromboembolic pulmonary hypertensionAcute pulmonary embolismPulmonary embolismFlowTriever SystemCause mortalityPulmonary hypertensionRV functionMechanical thrombectomyThromboembolic diseaseMedical Research Council dyspnea scoreHigh-risk pulmonary embolismTest distanceRapid hemodynamic improvementProportion of patientsRight ventricular functionSix-month outcomesQOL total scoreComers registryDyspnea scoreHemodynamic improvementMulticenter registryExercise capacityAcute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism.
Toma C, Jaber W, Weinberg M, Bunte M, Khandhar S, Stegman B, Gondi S, Chambers J, Amin R, Leung D, Kado H, Brown M, Sarosi M, Bhat A, Castle J, Savin M, Siskin G, Rosenberg M, Fanola C, Horowitz J, Pollak J. Acute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism. EuroIntervention 2023, 18: 1201-1212. PMID: 36349702, PMCID: PMC9936254, DOI: 10.4244/eij-d-22-00732.Peer-Reviewed Original ResearchConceptsHigh-risk PEDevice-related deathsPulmonary artery pressureMajor adverse eventsAdverse eventsMechanical thrombectomyFlowTriever SystemArtery pressureUS cohortLarge real-world populationMean pulmonary artery pressureImmediate haemodynamic improvementIntraprocedural adverse eventsPrimary safety endpointRight ventricle/Favorable safety profileIntensive care unitPulmonary embolism treatmentReal-world populationDyspnoea improvementHaemodynamic improvementMajor bleedingRisk PECardiac indexCause mortality