2023
Seasonal Malaria Chemoprevention Drug Levels and Drug Resistance Markers in Children With or Without Malaria in Burkina Faso: A Case-Control Study
Roh M, Zongo I, Haro A, Huang L, Somé A, Yerbanga R, Conrad M, Wallender E, Legac J, Aweeka F, Ouédraogo J, Rosenthal P. Seasonal Malaria Chemoprevention Drug Levels and Drug Resistance Markers in Children With or Without Malaria in Burkina Faso: A Case-Control Study. The Journal Of Infectious Diseases 2023, 228: 926-935. PMID: 37221018, PMCID: PMC10547452, DOI: 10.1093/infdis/jiad172.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionDrug levelsMonths of ageOdds ratioHigh-level SP resistanceSP-AQCase-control studyConditional logistic regressionLow drug levelsPrevalence of mutationsDrug resistance markersCase-control designResistance markersIncident malariaParasitemic childrenMalaria chemopreventionAntimalarial resistanceChildren 6Health facilitiesSP resistanceChildren 3Malaria incidenceDrug resistanceMalariaLogistic regression
2022
Ethical considerations in deploying triple artemisinin-based combination therapies for malaria: An analysis of stakeholders’ perspectives in Burkina Faso and Nigeria
Tindana P, Guissou R, Bolarinwa O, Tou F, de Haan F, Dhorda M, Dondorp A, Amaratunga C, Mokuolu O, Ouedraogo J, Cheah P. Ethical considerations in deploying triple artemisinin-based combination therapies for malaria: An analysis of stakeholders’ perspectives in Burkina Faso and Nigeria. PLOS ONE 2022, 17: e0273249. PMID: 36083995, PMCID: PMC9462557, DOI: 10.1371/journal.pone.0273249.Peer-Reviewed Original ResearchConceptsTriple artemisinin-based combination therapiesArtemisinin-based combination therapyCombination therapyArtemisinin resistanceUncomplicated Plasmodium falciparum malariaDrug resistancePlasmodium falciparum malariaMalaria-endemic countriesPartner drug resistanceAdditional side effectsUncomplicated malariaFalciparum malariaTreatment optionsEndemic countriesPediatric diseasesSide effectsACT failureMalariaTherapyBurkina FasoFocus group discussionsEthical considerationsTreatmentQualitative studyStakeholder engagement activitiesThe Strategy of Paratransgenesis for the Control of Malaria Transmission
Fofana A, Yerbanga R, Bilgo E, Ouedraogo G, Gendrin M, Ouedraogo J. The Strategy of Paratransgenesis for the Control of Malaria Transmission. Frontiers In Tropical Diseases 2022, 3: 867104. DOI: 10.3389/fitd.2022.867104.Peer-Reviewed Original ResearchMalaria parasitesGenetic engineering strategiesParatransgenesis approachWHO African RegionInsect-borne diseasesInsect hostsVector control measuresSpread of resistanceInsect vectorsImportant burdenGlobal deathsMalaria transmissionPlasmodium transmissionMalariaMicrobial strainsParatransgenesisSubtropical countriesEngineering strategiesDiseaseDeathParasitesControl measuresNovel strategyMosquitoesDifferent steps
2021
Nutritional status in young children prior to the malaria transmission season in Burkina Faso and Mali, and its impact on the incidence of clinical malaria
de Wit M, Cairns M, Compaoré Y, Sagara I, Kuepfer I, Zongo I, Barry A, Diarra M, Tapily A, Coumare S, Thera I, Nikiema F, Yerbanga R, Guissou R, Tinto H, Dicko A, Chandramohan D, Greenwood B, Ouedraogo J. Nutritional status in young children prior to the malaria transmission season in Burkina Faso and Mali, and its impact on the incidence of clinical malaria. Malaria Journal 2021, 20: 274. PMID: 34158054, PMCID: PMC8220741, DOI: 10.1186/s12936-021-03802-2.Peer-Reviewed Original ResearchConceptsClinical malaria incidenceSeasonal malaria chemopreventionMalaria transmission seasonClinical malariaNutritional statusMalaria incidenceMalaria chemopreventionSubsequent incidenceTransmission seasonMalaria seasonNutritional indicatorsEffects of malnutritionYoung childrenSymptomatic malariaScreening visitArm circumferenceLower incidenceModerate wastingHigh incidenceRandom effects Poisson modelBurkina FasoInsecticidal netsMalaria controlMalnutritionMalariaThe Duration of Protection from Azithromycin Against Malaria, Acute Respiratory, Gastrointestinal, and Skin Infections When Given Alongside Seasonal Malaria Chemoprevention: Secondary Analyses of Data from a Clinical Trial in Houndé, Burkina Faso, and Bougouni, Mali
Phiri M, Cairns M, Zongo I, Nikiema F, Diarra M, Yerbanga R, Barry A, Tapily A, Coumare S, Thera I, Kuepfer I, Milligan P, Tinto H, Dicko A, Ouédraogo J, Greenwood B, Chandramohan D, Sagara I. The Duration of Protection from Azithromycin Against Malaria, Acute Respiratory, Gastrointestinal, and Skin Infections When Given Alongside Seasonal Malaria Chemoprevention: Secondary Analyses of Data from a Clinical Trial in Houndé, Burkina Faso, and Bougouni, Mali. Clinical Infectious Diseases 2021, 73: e2379-e2386. PMID: 33417683, PMCID: PMC8492219, DOI: 10.1093/cid/ciaa1905.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionMass drug administrationMalaria chemopreventionPlacebo-controlled trialEvidence of protectionDuration of protectionHospital admissionAcute respiratoryIllness episodesWeeks postadministrationClinical trialsSkin infectionsSkin conditionsDrug AdministrationProfile of protectionAzithromycinPoisson regressionChild survivalSecondary analysisBurkina FasoDifferent causesExtent of protectionChemopreventionMalariaAdministrationHemoglobin change following first line treatment of uncomplicated falciparum malaria with artemether-lumefantrine and artesunate-amodiaquine in Burkina Faso
Zongo I, Compaore Y, Ouedraogo G, Nikiema F, Some F, Ouedraogo J. Hemoglobin change following first line treatment of uncomplicated falciparum malaria with artemether-lumefantrine and artesunate-amodiaquine in Burkina Faso. PAMJ Clinical Medicine 2021, 5 DOI: 10.11604/pamj-cm.2021.5.11.23991.Peer-Reviewed Original Research
2020
Efficacy of artemether-lumefantrine and artesunate-amodiaquine as first line therapy of uncomplicated malaria in Burkina Faso, 11 years after policy change
Zongo I, Compaoré Y, Nikiéma F, Zongo M, Barry N, Somé F, Kaboré N, Ouédraogo J. Efficacy of artemether-lumefantrine and artesunate-amodiaquine as first line therapy of uncomplicated malaria in Burkina Faso, 11 years after policy change. Pan African Medical Journal 2020, 35: 68. PMID: 32537072, PMCID: PMC7250195, DOI: 10.11604/pamj.2020.35.68.20849.Peer-Reviewed Original ResearchConceptsFirst-line therapyLine therapyUncomplicated malariaPolymerase chain reactionTreatment efficacyEarly treatment failureGood tolerability profileFirst-line treatmentParasitological responsePrimary endpointTolerability profileArtemether-lumefantrineTreatment failureLine treatmentASAQ groupDay 28Better efficacyBurkina FasoTherapyMalariaEfficacyChain reactionCompletion ratesTreatmentDays
2018
In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice
Bonkian L, Yerbanga R, Koama B, Soma A, Cisse M, Valea I, Tinto H, Ouedraogo J, Guigemde T, Traore/Coulibaly M. In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice. Evidence-based Complementary And Alternative Medicine 2018, 2018: 6859632. PMID: 29977316, PMCID: PMC5994278, DOI: 10.1155/2018/6859632.Peer-Reviewed Original ResearchArtemisinin-based combination therapyWorld Health OrganizationNMRI miceBody weightUncomplicated malaria treatmentAntiplasmodial activityVivo antiplasmodial activityPercentage of reductionFour-day treatmentControl of malariaExtract/Thin blood smearsCombination therapyMalaria treatmentPrimary treatmentControl groupDay fiveBlood smearsCandidate drugsHerbal medicineHealth OrganizationMalariaLeaf decoctionTreatmentParasitaemia
2017
TO VALUE THE EFFICIENCY OF PYRONARIDINE-ARTESUNATE AND ARTEMETHER-LUMEFANTRINE IN THE TREATMENT OF UNCOMPLICATED MALARIA OF PLASMODIUM SPP. IN BURKINA FASO
Barry N, Kaboré N, Kabré Z, Fofana A, Nikèma F, Compaoré D, Somé F, Zongo I, Djimdé A, Ouédraogo J. TO VALUE THE EFFICIENCY OF PYRONARIDINE-ARTESUNATE AND ARTEMETHER-LUMEFANTRINE IN THE TREATMENT OF UNCOMPLICATED MALARIA OF PLASMODIUM SPP. IN BURKINA FASO. BMJ Global Health 2017, 2: a24. DOI: 10.1136/bmjgh-2016-000260.62.Peer-Reviewed Original ResearchArtemether-lumefantrineUncomplicated malariaTreatment failurePA groupAL groupEffective malaria vaccineStandard of careNew therapeutic drugsPyronaridine-ArtesunateMalaria vaccinePatient groupTherapeutic failureFirst episodeTreatment responseDay 28Malaria diagnosisDay 42Burkina FasoMalaria controlEvidence baseLess casesPlasmodium sppTherapeutic drugsMalariaBobo-Dioulasso
2016
A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms
Ménard D, Khim N, Beghain J, Adegnika A, Shafiul-Alam M, Amodu O, Rahim-Awab G, Barnadas C, Berry A, Boum Y, Bustos M, Cao J, Chen J, Collet L, Cui L, Thakur G, Dieye A, Djallé D, Dorkenoo M, Eboumbou-Moukoko C, Espino F, Fandeur T, Ferreira-da-Cruz M, Fola A, Fuehrer H, Hassan A, Herrera S, Hongvanthong B, Houzé S, Ibrahim M, Jahirul-Karim M, Jiang L, Kano S, Ali-Khan W, Khanthavong M, Kremsner P, Lacerda M, Leang R, Leelawong M, Li M, Lin K, Mazarati J, Ménard S, Morlais I, Muhindo-Mavoko H, Musset L, Na-Bangchang K, Nambozi M, Niaré K, Noedl H, Ouédraogo J, Pillai D, Pradines B, Quang-Phuc B, Ramharter M, Randrianarivelojosia M, Sattabongkot J, Sheikh-Omar A, Silué K, Sirima S, Sutherland C, Syafruddin D, Tahar R, Tang L, Touré O, Tshibangu-wa-Tshibangu P, Vigan-Womas I, Warsame M, Wini L, Zakeri S, Kim S, Eam R, Berne L, Khean C, Chy S, Ken M, Loch K, Canier L, Duru V, Legrand E, Barale J, Stokes B, Straimer J, Witkowski B, Fidock D, Rogier C, Ringwald P, Ariey F, Mercereau-Puijalon O. A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms. New England Journal Of Medicine 2016, 374: 2453-2464. PMID: 27332904, PMCID: PMC4955562, DOI: 10.1056/nejmoa1513137.Peer-Reviewed Original ResearchConceptsK13 mutationsRing-stage survival assayK13-propeller polymorphismsPlasmodium falciparum resistanceA578S mutationParasite clearanceRare nonsynonymous mutationsFalciparum resistanceAntimalarial resistanceArtemisinin resistanceNationwide surveillanceGlobal burdenSentinel sitesGeographic disparitiesSurvival assaysP. falciparum genesMalariaPropeller domainMajor determinantArtemisininMutationsNonsynonymous mutationsSuch resistancePolymorphismPatientsNeemazal ® as a possible alternative control tool for malaria and African trypanosomiasis?
Yerbanga R, Rayaisse J, Vantaux A, Salou E, Mouline K, Hien F, Habluetzel A, Dabiré R, Ouédraogo J, Solano P, Lefèvre T. Neemazal ® as a possible alternative control tool for malaria and African trypanosomiasis? Parasites & Vectors 2016, 9: 263. PMID: 27146309, PMCID: PMC4857419, DOI: 10.1186/s13071-016-1538-x.Peer-Reviewed Original ResearchConceptsAfrican trypanosomiasisEffect of bloodOral dosesBehavioral alterationsConclusionThis studyAnthropophilic rateDifferent dosesMembrane feedingAlternative control toolsDosesCalf odourPromising activityMalariaMiceBloodDoseVector control programsHost stimuliAdditional researchControl programsPlant remediesBehavioral responsesG. palpalis gambiensisTrypanosomiasisBloodmealLipid-Based Nutrient Supplements Plus Malaria and Diarrhea Treatment Increase Infant Development Scores in a Cluster-Randomized Trial in Burkina Faso 1–3
Prado E, Abbeddou S, Yakes Jimenez E, Somé J, Ouédraogo Z, Vosti S, Dewey K, Brown K, Hess S, Ouédraogo J. Lipid-Based Nutrient Supplements Plus Malaria and Diarrhea Treatment Increase Infant Development Scores in a Cluster-Randomized Trial in Burkina Faso 1–3. Journal Of Nutrition 2016, 146: 814-822. PMID: 26962193, DOI: 10.3945/jn.115.225524.Peer-Reviewed Original ResearchAge 18 moPersonal-social developmentRural Burkina FasoSQ-LNSsIC groupLipid-based nutrient supplementsInfant Development scoresAge 9Treatment of malariaRapid brain developmentNutrient supplementsSecondary outcomesPlacebo tabletsAdequate nutritionIC subgroupBrain developmentIC childrenMalariaNonintervention cohortInfant developmentTrialsDevelopment scoresBurkina FasoChildrenTreatment
2015
Anemia And Iron Supplementation Is Not Associated with Malaria in Young Burkinabe Children
Some J, Abbeddou S, Jimenez E, Ouedraogo Z, Ouedraogo J, Brown K, Hess S. Anemia And Iron Supplementation Is Not Associated with Malaria in Young Burkinabe Children. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.757.9.Peer-Reviewed Original ResearchLipid-based nutrient supplementsRapid diagnostic testsYoung Burkinabe childrenBurkinabe childrenIron supplementationFe supplementsPositive malaria rapid diagnostic testPositive rapid diagnostic testMalaria rapid diagnostic testsRandomized clinical trialsIncidence of malariaMo of ageMalaria episodesAntimalarial treatmentSevere anemiaModerate anemiaClinical trialsAnthelminthic treatmentHome visitsMalaria diagnosisHemoglobin concentrationMalaria incidenceIron treatmentDiagnostic testsMalariaTreated Malaria Does Not Affect Physical Growth And Hemoglobin Concentration of Young Children in Burkina Faso
Some J, Abbeddou S, Jimenez E, Hess S, Ouedraogo Z, Guissou R, Vosti S, Ouedraogo J, Brown K. Treated Malaria Does Not Affect Physical Growth And Hemoglobin Concentration of Young Children in Burkina Faso. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.757.7.Peer-Reviewed Original ResearchLipid-based nutrient supplementationRapid diagnostic testsPhysical growthHemoglobin concentrationZ-scoreYoung Burkinabe childrenLength z-scoreCause of anemiaAssociation of malariaAge z-scoreYoung childrenMo of ageMalaria episodesMorbidity assessmentBurkinabe childrenMean changeMalariaDiagnostic testsDifferent dosesEarly childhoodChildrenDiarrheaFeverEpisodesFrequency categoriesSmall-quantity Lipid-based Nutrient Supplements, Together with Malaria and Diarrhea Treatment, Improve Growth and Development in Young Burkinabe Children
Hess S, Abbeddou S, Jimenez E, Some J, Prado E, Ouédraogo Z, Guissou R, Vosti S, Ouédraogo J, Brown K. Small-quantity Lipid-based Nutrient Supplements, Together with Malaria and Diarrhea Treatment, Improve Growth and Development in Young Burkinabe Children. European Journal Of Nutrition & Food Safety 2015, 5: 715-716. DOI: 10.9734/ejnfs/2015/21046.Peer-Reviewed Original Research
2014
Antiplasmodial and Antioxidant Activities of Saye: A Traditional Herbal Remedy for Malaria
Da O, Coulibaly M, Yerbanga R, Koama B, Ouedraogo N, Tamboura S, Dakuyo Z, Sekhoacha M, Nikiema J, Ouedraogo G, Matsabisa M, Ouedraogo J. Antiplasmodial and Antioxidant Activities of Saye: A Traditional Herbal Remedy for Malaria. American Journal Of Biochemistry And Molecular Biology 2014, 4: 155-166. DOI: 10.3923/ajbmb.2014.155.166.Peer-Reviewed Original ResearchLipid peroxidationDay suppressive testDecocted extractTraditional herbal remediesInfected miceSuppressive testAntioxidant activityPreventive agentSame doseRat liver homogenateBody weightOxidative stress diseasesHerbal remediesLiver homogenatesTotal phenol contentInhibition of ionStress diseasesPhyllanthus amarusQE/Antioxidant potentialHighest total phenol contentInhibitionPhyllantus amarusCochlospermum planchoniiMalariaA barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains
Preston M, Campino S, Assefa S, Echeverry D, Ocholla H, Amambua-Ngwa A, Stewart L, Conway D, Borrmann S, Michon P, Zongo I, Ouédraogo J, Djimde A, Doumbo O, Nosten F, Pain A, Bousema T, Drakeley C, Fairhurst R, Sutherland C, Roper C, Clark T. A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. Nature Communications 2014, 5: 4052. PMID: 24923250, PMCID: PMC4082634, DOI: 10.1038/ncomms5052.Peer-Reviewed Original ResearchConceptsMajor public health problemValuable public health toolSingle nucleotide polymorphismsPublic health problemDrug-resistant parasitesPublic health toolPlasmodium falciparum strainsGlobal eradication campaignHealth problemsFalciparum strainsCase managementHealth toolsPlasmodium falciparumParasite migrationElimination areaEradication campaignApicoplast genomeParasitesPolymorphismInfectionMalariaInternational air travelFalciparumBurkinabe infants given small quantity lipid‐based nutrient supplements and illness treatment in infancy score higher in motor, language, and personal‐social development (251.1)
Prado E, Abbeddou S, Jimenez E, Somé J, Ouédraogo Z, Vosti S, Dewey K, Hess S, Ouédraogo J, Brown K. Burkinabe infants given small quantity lipid‐based nutrient supplements and illness treatment in infancy score higher in motor, language, and personal‐social development (251.1). The FASEB Journal 2014, 28 DOI: 10.1096/fasebj.28.1_supplement.251.1.Peer-Reviewed Original ResearchSmall-quantity lipid-based nutrient supplementsLipid-based nutrient supplementsPersonal-social developmentNon-intervention communitiesYoung Burkinabe childrenTreatment of malariaMonths of ageRural Burkina FasoNutrient supplementsSQ-LNSBurkinabe childrenIllness treatmentBrain growthAdequate nutritionMacronutrient metabolismBrain developmentIC childrenMelinda Gates FoundationDevelopment of motorChildrenMalariaLowest decileTreatmentGrant funding sourcesSDEffectiveness of artesunate–amodiaquine vs. artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Nanoro, Burkina Faso: a non‐inferiority randomised trial
Tinto H, Diallo S, Zongo I, Guiraud I, Valea I, Kazienga A, Kpoda H, Sorgho H, Ouédraogo J, Guiguemdé T, D'Alessandro U. Effectiveness of artesunate–amodiaquine vs. artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Nanoro, Burkina Faso: a non‐inferiority randomised trial. Tropical Medicine And International Health 2014, 19: 469-475. PMID: 24494602, DOI: 10.1111/tmi.12274.Peer-Reviewed Original ResearchConceptsArtemether-lumefantrineUncomplicated malariaFalciparum malariaUncomplicated falciparum malariaLow cure rateParents/guardiansAL armASAQ armParasitological responseFirst doseStudy nursesStudy armsRecrudescent infectionsCombination therapyCure rateTreatment administrationEndemic countriesDay 28Efficacy studiesNew infectionsDay 14Routine practiceMalariaBurkina FasoASAQ
2013
P084: Analysis of therapeutic efficacies of amodiaquine-arstesunate and artemether-lumefantrine for treatment of uncomplicated falciparum malaria in Burkina Faso five years after their implementation
Nikiema F, Zongo I, Some F, Ouedraogo J, Penali L. P084: Analysis of therapeutic efficacies of amodiaquine-arstesunate and artemether-lumefantrine for treatment of uncomplicated falciparum malaria in Burkina Faso five years after their implementation. Antimicrobial Resistance & Infection Control 2013, 2: p84. PMCID: PMC3688426, DOI: 10.1186/2047-2994-2-s1-p84.Peer-Reviewed Original Research