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Translational Research in Malaria
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INFORMATION FOR

Projects

  • Antimalarial Pharmacology and Pharmacodynamics in Uganda

    An ongoing study in Tororo, Uganda aims to characterize the PK/PD and pharmacogenetics of antimalarials in the context of HIV co-infection, development and pregnancy. Additional studies aim to understand important interactions between the most widely used antiretrovirals and antimalarials.

  • Host Response to Malaria

    Through use of next-generation sequencing, we are studying the host response to malaria and antimalarial treatment in the setting of HIV and pregnancy.

  • Immunogenetics of Malaria Susceptibility

    Innate Immune Responses in Populations with Differing Susceptibility to Malaria in Burkina Faso

  • Dynamic Malaria Modeling

    Our mathematical modeling studies aim to understand the PK/PD of antimalarials used in treatment and prevention settings, as well as the impact of drug usage on the emergence and spread of antimalarial resistance. Studies in conjunction with the several modeling groups within and outside of Yale.