2014
Ex vivo anti-malarial drugs sensitivity profile of Plasmodium falciparum field isolates from Burkina Faso five years after the national policy change
Tinto H, Bonkian L, Nana L, Yerbanga I, Lingani M, Kazienga A, Valéa I, Sorgho H, Kpoda H, Guiguemdé T, Ouédraogo J, Mens P, Schallig H, D’Alessandro U. Ex vivo anti-malarial drugs sensitivity profile of Plasmodium falciparum field isolates from Burkina Faso five years after the national policy change. Malaria Journal 2014, 13: 207. PMID: 24885950, PMCID: PMC4049403, DOI: 10.1186/1475-2875-13-207.Peer-Reviewed Original ResearchConceptsP. falciparum sensitivityVivo studiesFirst-line treatmentPlasmodium falciparum fieldAnti-malarial drugsEx vivo studyDrug sensitivity profilesDHA-PPQChloroquine resistanceIC50 valuesPartner drugsDrug efficacy testsDrug measurementsInhibitory concentration valuesMonodesethylamodiaquinePiperaquineEfficacy of ALHigher IC50 valuesPlasmodium falciparumDihydroartemisininFive yearsCellular proliferationDrugsRecent reportsLumefantrine
2001
In vitro susceptibility of 232 isolates of Plasmodium falciparum to antimalarials in Burkina Faso (West Africa).
Tinto H, Ouedraogo J, Traoré B, Coulibaly S, Guiguemde T. In vitro susceptibility of 232 isolates of Plasmodium falciparum to antimalarials in Burkina Faso (West Africa). Bulletin De La Société De Pathologie Exotique 2001, 94: 188-91. PMID: 16579075.Peer-Reviewed Original ResearchConceptsP. falciparumPlasmodium falciparumCells/mm3Chloroquine-resistant strainsInclusion criteriaReference centerParasite countsSingle infectionResistant isolatesSignificant positive correlationParasite growthPersistence of resistanceFalciparumHalofantrineBobo-DioulassoSignificant increaseMefloquineIC50 valuesPositive correlationIsolatesQuinineSusceptibilityPatientsBurkina FasoIncubation period
1998
In vitro sensitivity of Plasmodium falciparum to halofantrine compared with chloroquine, quinine and mefloquine in the region of Bobo-Dioulasso, Burkina Faso (West Africa).
Ouédraogo J, Dutheil Y, Tinto H, Traoré B, Zampa H, Tall F, Coulibaly S, Guiguemdé T. In vitro sensitivity of Plasmodium falciparum to halofantrine compared with chloroquine, quinine and mefloquine in the region of Bobo-Dioulasso, Burkina Faso (West Africa). Tropical Medicine And International Health 1998, 3: 381-4. PMID: 9623943.Peer-Reviewed Original ResearchConceptsChloroquine-resistant isolatesMean IC50 valuesChloroquine-sensitive isolatesDrug-resistant isolatesBobo-DioulassoIC50 valuesProportion of isolatesParasite densityMefloquineSignificant positive correlationHalofantrinePlasmodium falciparumNew antimalarialsCase of quinineSignificant differencesQuinineChloroquineAntimalarialsPositive correlationIsolatesBurkina FasoProportion