2018
Effectiveness of a community-based educational programme in reducing the cumulative incidence and prevalence of human Taenia solium cysticercosis in Burkina Faso in 2011–14 (EFECAB): a cluster-randomised controlled trial
Carabin H, Millogo A, Ngowi H, Bauer C, Dermauw V, Koné A, Sahlu I, Salvator A, Preux P, Somé T, Tarnagda Z, Gabriël S, Cissé R, Ouédraogo J, Cowan L, Boncoeur-Martel M, Dorny P, Ganaba R. Effectiveness of a community-based educational programme in reducing the cumulative incidence and prevalence of human Taenia solium cysticercosis in Burkina Faso in 2011–14 (EFECAB): a cluster-randomised controlled trial. The Lancet Global Health 2018, 6: e411-e425. PMID: 29530423, PMCID: PMC5873982, DOI: 10.1016/s2214-109x(18)30027-5.Peer-Reviewed Original ResearchConceptsCumulative incidenceHuman cysticercosisActive cysticercosisHuman Taenia solium cysticercosisCommunity-based educational interventionDrug-free interventionsTaenia solium transmissionCommunity-based educational programTaenia solium cysticercosisLow-resource settingsPrevalence of cysticercosisEligible villagesPrimary outcomeUS National InstitutesSolium transmissionBlood samplesFinal sample sizeControl groupSolium cysticercosisCysticercosisCysticercosis prevalenceRandomisationEducational interventionPrevalenceIncidenceIn Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice
Bonkian L, Yerbanga R, Koama B, Soma A, Cisse M, Valea I, Tinto H, Ouedraogo J, Guigemde T, Traore/Coulibaly M. In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice. Evidence-based Complementary And Alternative Medicine 2018, 2018: 6859632. PMID: 29977316, PMCID: PMC5994278, DOI: 10.1155/2018/6859632.Peer-Reviewed Original ResearchArtemisinin-based combination therapyWorld Health OrganizationNMRI miceBody weightUncomplicated malaria treatmentAntiplasmodial activityVivo antiplasmodial activityPercentage of reductionFour-day treatmentControl of malariaExtract/Thin blood smearsCombination therapyMalaria treatmentPrimary treatmentControl groupDay fiveBlood smearsCandidate drugsHerbal medicineHealth OrganizationMalariaLeaf decoctionTreatmentParasitaemia
2016
Comparison of Preventive and Therapeutic Zinc Supplementation in Young Children in Burkina Faso: A Cluster-Randomized, Community-Based Trial 1–3
Becquey E, Ouédraogo C, Hess S, Rouamba N, Prince L, Ouédraogo J, Vosti S, Brown K. Comparison of Preventive and Therapeutic Zinc Supplementation in Young Children in Burkina Faso: A Cluster-Randomized, Community-Based Trial 1–3. Journal Of Nutrition 2016, 146: 2058-2066. PMID: 27489011, DOI: 10.3945/jn.116.230128.Peer-Reviewed Original ResearchConceptsTherapeutic zinc supplementationPreventive zinc supplementationZinc supplementationNonintervention controlsMalaria incidenceDiarrhea incidenceZinc-deficient populationsPrevalence of diarrheaPlasma zinc concentrationTreatment of diarrheaPrimary outcomeBurkinabe childrenMSC groupLower incidenceNIC groupStudy groupTreatment groupsPrimary analysisControl groupDiarrheaIncidenceSupplementationTrial 1Young childrenFever
2015
Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso
Zongo I, Milligan P, Compaore Y, Some A, Greenwood B, Tarning J, Rosenthal P, Sutherland C, Nosten F, Ouedraogo J. Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso. Antimicrobial Agents And Chemotherapy 2015, 59: 4387-4396. PMID: 25918149, PMCID: PMC4505196, DOI: 10.1128/aac.04923-14.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionMalaria chemopreventionAlternative drugsControl groupPrimary outcome measureSeasonal malaria transmissionRandomized noninferiority trialPotential alternative drugDihydroartemisinin-PiperaquinePfdhps mutationsClinical malariaMalaria attacksSulfadoxine-pyrimethamineOdds ratioNoninferiority trialOutcome measuresDHAPQChildren 3Malaria transmissionDrug resistanceAntifolate resistanceChemopreventionChildrenAmodiaquineTrials
2014
Selection of Drug Resistance-Mediating Plasmodium falciparum Genetic Polymorphisms by Seasonal Malaria Chemoprevention in Burkina Faso
Somé A, Zongo I, Compaoré Y, Sakandé S, Nosten F, Ouédraogo J, Rosenthal P. Selection of Drug Resistance-Mediating Plasmodium falciparum Genetic Polymorphisms by Seasonal Malaria Chemoprevention in Burkina Faso. Antimicrobial Agents And Chemotherapy 2014, 58: 3660-3665. PMID: 24733476, PMCID: PMC4068591, DOI: 10.1128/aac.02406-14.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionAQ/SPMalaria chemopreventionSingle nucleotide polymorphismsP. falciparum crtPfcrt 76TResistance-mediating polymorphismsMalaria control measuresPCR-positive samplesMonthly DPPfdhfr 108NPfdhfr 51IPfmdr1 86YSulfadoxine-pyrimethamineTreatment armsDevelopment of resistanceTransmission seasonControl groupP. falciparumSNP prevalenceGenetic polymorphismsRegular useAntifolate antimalarialsMonthsBurkina Faso
2013
Comparison of preventive and therapeutic zinc supplementation programs for young children in Burkina Faso: a randomized, masked, community‐based trial
Becquey E, Ouedraogo C, Hess S, Rouamba N, Prince L, Vosti S, Ouedraogo J, Brown K. Comparison of preventive and therapeutic zinc supplementation programs for young children in Burkina Faso: a randomized, masked, community‐based trial. The FASEB Journal 2013, 27: 845.19-845.19. DOI: 10.1096/fasebj.27.1_supplement.845.19.Peer-Reviewed Original ResearchOral rehydration saltsDiarrhea incidenceSUPP groupThrasher Research FundCommunity-based trialLower diarrhea incidenceRehydration saltsUncomplicated diarrheaChildren 6Home visitsDiarrhea preventionControl groupZn supplementationDiarrheaSupplementation programsIncidenceGreat benefitFree treatmentYoung childrenTreatmentGroupFeverLess lengthBurkina FasoMalaria