2020
Evaluation of seasonal malaria chemoprevention in two areas of intense seasonal malaria transmission: Secondary analysis of a household-randomised, placebo-controlled trial in Houndé District, Burkina Faso and Bougouni District, Mali
Cairns M, Sagara I, Zongo I, Kuepfer I, Thera I, Nikiema F, Diarra M, Yerbanga S, Barry A, Tapily A, Coumare S, Milligan P, Tinto H, Ouédraogo J, Chandramohan D, Greenwood B, Djimde A, Dicko A. Evaluation of seasonal malaria chemoprevention in two areas of intense seasonal malaria transmission: Secondary analysis of a household-randomised, placebo-controlled trial in Houndé District, Burkina Faso and Bougouni District, Mali. PLOS Medicine 2020, 17: e1003214. PMID: 32822362, PMCID: PMC7442230, DOI: 10.1371/journal.pmed.1003214.Peer-Reviewed Original ResearchConceptsSeasonal malaria chemopreventionMalaria chemopreventionUncomplicated malariaTransmission seasonIntense seasonal malaria transmissionDay 28 PCRParasitological response rateUncomplicated clinical malariaPlacebo-controlled trialIncidence of hospitalisationSeasonal malaria transmissionIncidence rate ratiosBurden of malariaRapid diagnostic testsBougouni DistrictAsymptomatic malariaClinical malariaPlacebo groupStudy drugMalaria parasitaemiaAge range 3Parent trialAmodiaquine resistancePrevalence ratiosProtective efficacy
2014
Asymptomatic Malaria Infection Affects the Interpretation of Biomarkers of Iron and Vitamin A Status, Even after Adjusting for Systemic Inflammation, but Does Not Affect Plasma Zinc Concentrations among Young Children in Burkina Faso
Wessells K, Hess S, Ouédraogo Z, Rouamba N, Ouédraogo J, Brown K. Asymptomatic Malaria Infection Affects the Interpretation of Biomarkers of Iron and Vitamin A Status, Even after Adjusting for Systemic Inflammation, but Does Not Affect Plasma Zinc Concentrations among Young Children in Burkina Faso. Journal Of Nutrition 2014, 144: 2050-2058. PMID: 25411038, DOI: 10.3945/jn.114.200345.Peer-Reviewed Original ResearchMeSH KeywordsAcute-Phase ProteinsAcute-Phase ReactionAdolescentAnemia, Iron-DeficiencyAsymptomatic DiseasesBiomarkersBurkina FasoChildC-Reactive ProteinCross-Sectional StudiesDietary SupplementsFemaleFerritinsHemoglobinsHumansIron, DietaryLinear ModelsMalariaMaleMicronutrientsNutritional StatusOrosomucoidPrevalenceProteinsRandomized Controlled Trials as TopicRetinol-Binding ProteinsVitamin AVitamin A DeficiencyZincConceptsAcute phase proteinsElevated acute phase proteinsAsymptomatic malaria infectionsMalaria infectionMicronutrient statusBiomarkers of ironSoluble transferrin receptorVitamin A StatusAcute phase responseIndicators of ironPlasma zinc concentrationAsymptomatic malariaAsymptomatic childrenSystemic inflammationMalaria parasitemiaHigh prevalenceA StatusPhase proteinsInterpretation of biomarkersZinc statusIron deficiencyLower RBPHRP2PrevalenceMicronutrient deficiencies