Haidong Lu, PhD
Cards
Research
About
Contact/Administration
Research
About
Contact/Administration
Research
Featured Publication
Publications Overview
- 38 Publications
- 689 Citations
- 10 Yale Co-Authors
Featured Publication
Publications Overview
- 38 Publications
- 689 Citations
- 10 Yale Co-Authors
Featured Publication
Titles
Assistant Professor of Internal Medicine
Appointments
Contact Info
Featured Publication
Publications Overview
- 38 Publications
- 689 Citations
- 10 Yale Co-Authors
Featured Publication
Publications Overview
- 38 Publications
- 689 Citations
- 10 Yale Co-Authors
Featured Publication
Titles
Assistant Professor of Internal Medicine
Appointments
Contact Info
Featured Publication
Publications Overview
- 38 Publications
- 689 Citations
- 10 Yale Co-Authors
Featured Publication
Publications Overview
- 38 Publications
- 689 Citations
- 10 Yale Co-Authors
Featured Publication
About
Titles
Assistant Professor of Internal Medicine
Biography
Dr. Haidong Lu is an epidemiologist and methodologist who is passionate about bridging the disciplines of epidemiology, statistics, data science, population health, and clinical research. His research focuses on leveraging appropriate health data science techniques to draw causal inferences from observational data (e.g., electronic health records). Through this approach, he strives to generate accurate and impactful real-world evidence that informs clinical and regulatory decision-making. In addition to observational studies, he is dedicated to enhancing methodologies for analyzing randomized controlled trials, particularly in addressing challenges related to non-compliance and generalizability. Dr. Lu is also interested in artificial intelligence in learning health systems. His current substantive research interests center around substance use and pharmacoepidemiology. Dr. Lu earned a PhD in Epidemiology (major) and Biostatistics (minor) from UNC Gillings School of Global Public Health, and a master's degree from Johns Hopkins Bloomberg School of Public Health. He is also clinically trained with a degree in pharmacy, further reinforcing his diverse and extensive background in health-related fields.
Appointments
General Internal Medicine
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- PhD
- The University of North Carolina Gillings School of Global Public Health, Epidemiology (Major) and Biostatistics (Minor)
Research
Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0002-7908-2517
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Gregg Gonsalves, PhD
David Fiellin, MD
David S. Fink, PhD
Lauretta Grau, PhD
Benjamin Howell, MD, MPH, MHS
Christopher T Rentsch, PhD, FISPE
Publications
Featured Publications
Toward a Clearer Definition of Selection Bias When Estimating Causal Effects
Lu H, Cole S, Howe C, Westreich D. Toward a Clearer Definition of Selection Bias When Estimating Causal Effects. Epidemiology 2022, 33: 699-706. PMID: 35700187, PMCID: PMC9378569, DOI: 10.1097/ede.0000000000001516.Peer-Reviewed Original ResearchMeSH KeywordsRevisiting Overadjustment Bias
Lu H, Cole S, Platt R, Schisterman E. Revisiting Overadjustment Bias. Epidemiology 2021, 32: e22-e23. PMID: 34172691, DOI: 10.1097/ede.0000000000001377.Peer-Reviewed Original ResearchClinical Effectiveness of Integrase Strand Transfer Inhibitor–Based Antiretroviral Regimens Among Adults With Human Immunodeficiency Virus: A Collaboration of Cohort Studies in the United States and Canada
Lu H, Cole S, Westreich D, Hudgens M, Adimora A, Althoff K, Silverberg M, Buchacz K, Li J, Edwards J, Rebeiro P, Lima V, Marconi V, Sterling T, Horberg M, Gill M, Kitahata M, Eron J, Moore R. Clinical Effectiveness of Integrase Strand Transfer Inhibitor–Based Antiretroviral Regimens Among Adults With Human Immunodeficiency Virus: A Collaboration of Cohort Studies in the United States and Canada. Clinical Infectious Diseases 2020, 73: e1408-e1414. PMID: 32780095, PMCID: PMC8492356, DOI: 10.1093/cid/ciaa1037.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsIntegrase strand transfer inhibitorsHuman immunodeficiency virusHazard ratioEFV groupAntiretroviral therapyStrand transfer inhibitorsClinical outcomesRisk differenceINSTI groupComposite outcomeImmunodeficiency virusClinical effectivenessNorth American AIDS Cohort CollaborationFirst-line antiretroviral therapyEnd-stage liver diseaseLong-term clinical effectivenessEnd-stage renal diseaseLong-term clinical outcomesComposite clinical outcomeFirst ART regimenInitial ART regimensAdverse clinical outcomesModern antiretroviral therapyTransfer inhibitorsAcute myocardial infarctionFour targets: an enhanced framework for guiding causal inference from observational data
Lu H, Li F, Lesko C, Fink D, Rudolph K, Harhay M, Rentsch C, Fiellin D, Gonsalves G. Four targets: an enhanced framework for guiding causal inference from observational data. International Journal Of Epidemiology 2024, 54: dyaf003. PMID: 39868475, PMCID: PMC11769716, DOI: 10.1093/ije/dyaf003.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsSelection Bias Requires Selection: The Case of Collider Stratification Bias
Lu H, Gonsalves G, Westreich D. Selection Bias Requires Selection: The Case of Collider Stratification Bias. American Journal Of Epidemiology 2023, 193: 407-409. PMID: 37939152, PMCID: PMC10911840, DOI: 10.1093/aje/kwad213.Peer-Reviewed Original Research
2025
Frequency and Intensity of Depressive Symptoms and Frequency of Prescribed Opioid Use Among Older Adults in the United States: Results of a National Survey.
Zhu X, Ge S, Ma W, Wu L, Ma H, Hu J, Lu H, Lin X. Frequency and Intensity of Depressive Symptoms and Frequency of Prescribed Opioid Use Among Older Adults in the United States: Results of a National Survey. J Addict Nurs 2025 PMID: 39919217, DOI: 10.1097/JAN.0000000000000604.Peer-Reviewed Original ResearchSpatiotemporal Trends of Birth Defects in North Carolina, 2003-2015
Lu H, Olshan AF, Serre ML, Anthony KM, Fry RC, Forestieri NE, Keil AP. Spatiotemporal Trends of Birth Defects in North Carolina, 2003-2015. Annals of Epidemiology. Revise & Resubmission.Peer-Reviewed Original Research
2024
Trends in Opioid Use Disorder in the Veterans Health Administration, 2005-2022
Gorfinkel L, Malte C, Fink D, Mannes Z, Wall M, Olfson M, Livne O, Keyhani S, Keyes K, Martins S, Cerdá M, Gutkind S, Maynard C, Saxon A, Simpson T, Gonsalves G, Lu H, McDowell Y, Hasin D. Trends in Opioid Use Disorder in the Veterans Health Administration, 2005-2022. JAMA Network Open 2024, 7: e2451821. PMID: 39705031, PMCID: PMC11662256, DOI: 10.1001/jamanetworkopen.2024.51821.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsVeterans Health AdministrationOpioid use disorder diagnosisNon-Hispanic white patientsOpioid use disorderPrevalence of opioid use disorderCross-sectional studyHealth AdministrationVHA Corporate Data WarehouseVeterans Health Administration facilitiesElectronic health record dataNational Veterans Health AdministrationVeterans Health Administration patientsRecord dataNon-Hispanic Black patientsElectronic medical record dataContinued public health effortsWhite patientsHealth record dataPublic health effortsCorporate Data WarehouseMedical record dataMultivariate logistic regression modelUse disorderLogistic regression modelsBurden of opioid use disorderRevisiting Representativeness
Lu H, Zivich PN, Rudulph JE, Liew Z, Mukherjee B, Li F. Revisiting Representativeness. International Journal of Epidemiology. Under Review.Peer-Reviewed Original ResearchReducing Information and Selection Bias in EHR-Linked Biobanks via Genetics-Informed Multiple Imputation and Sample Weighting
Salvatore M, Kundu R, Du J, Friese CR, Mondul AM, Hanauer D, Lu H, Pearce CL, Mukherjee B. Reducing Information and Selection Bias in EHR-Linked Biobanks via Genetics-Informed Multiple Imputation and Sample Weighting. Under Review.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
Activities
activity Epidemiologic Methods
03/05/2024 - PresentJournal ServiceAssociate Editoractivity Design and Analysis Group (DAG)
2024 - PresentAdvisory BoardsCo-ChairDetailsThe Veterans Aging Cohort Study (VACS)activity Yale Pharmacoepidemiology Workgroup
2024 - PresentAdvisory BoardsCo-FounderDetailsYale Universityactivity AJE Advances: Research in Epidemiology
2024 - PresentJournal ServiceAssociate Editor
Honors
honor K99/R00 Pathway to Independence Award
02/01/2023National AwardNIH/NIDADetailsUnited Stateshonor The Lilienfeld Postdoctoral Prize Paper Award Finalist
01/01/2023National AwardThe Society for Epidemiologic ResearchDetailsUnited Stateshonor ViiV Healthcare Fellowship
06/01/2019Regional AwardUNC Gillings School of Global Public HealthDetailsUnited Stateshonor The Miriam E. Brailey Fund
04/01/2016Regional AwardJohns Hopkins Bloomberg School of Public HealthDetailsUnited States
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Contacts
Locations
E.S. Harkness Memorial Hall
Academic Office
367 Cedar Street
New Haven, CT 06510