2001
Dynactin-Dependent, Dynein-Driven Vesicle Transport in the Absence of Membrane Proteins A Role for Spectrin and Acidic Phospholipids
Muresan V, Stankewich M, Steffen W, Morrow J, Holzbaur E, Schnapp B. Dynactin-Dependent, Dynein-Driven Vesicle Transport in the Absence of Membrane Proteins A Role for Spectrin and Acidic Phospholipids. Molecular Cell 2001, 7: 173-183. PMID: 11172722, DOI: 10.1016/s1097-2765(01)00165-4.Peer-Reviewed Original ResearchConceptsVesicle transportAcidic phospholipidsAxonal vesiclesProtein-free liposomesAbsence of membranesPH domainDependent motilityCytosolic factorsDynactinSpectrinEssential roleSpectrin polypeptidesVesiclesMembranePhospholipidsAxonal transportMotilitySoluble componentsContext of liposomesDyneinCytosolPolypeptideTransportRoleRetrograde axonal transport
1987
Spectrin Is Associated With Membrane-Bound Actin Filaments in Platelets and Is Hydrolyzed by the Ca2+-Dependent Protease During Platelet Activation
Fox J, Reynolds C, Morrow J, Phillips D. Spectrin Is Associated With Membrane-Bound Actin Filaments in Platelets and Is Hydrolyzed by the Ca2+-Dependent Protease During Platelet Activation. Blood 1987, 69: 537-545. DOI: 10.1182/blood.v69.2.537.537.Peer-Reviewed Original ResearchActin filamentsDependent proteasePlasma membraneRBC spectrinSubmembranous actin filamentsActin-binding proteinsBeta chainMembrane-bound filamentsActin filament networkTriton XImmunoprecipitation experimentsMinor polypeptidesFilament networkSpectrinGlycoprotein IbBrain spectrinDifferential centrifugationPresence of Ca2ProteaseLysatesPolyacrylamide gelsUnstimulated plateletsPolypeptideUnidentified componentsN-ethylmaleimide