Publications

• APOBEC-1 deletion enhances cisplatin-induced acute kidney injury.Guo X, Blanc V, Davidson NO, Velazquez H, Chen TM, Moledina DG, Moeckel GW, Safirstein RL, Desir GV. Sci Rep. 2023 Dec 14; 2023 Dec 14. PMID: 38097707.
• Urine Uromodulin as a Biomarker of Kidney Tubulointerstitial Fibrosis.Melchinger H, Calderon-Gutierrez F, Obeid W, Xu L, Shaw MM, Luciano RL, Kuperman M, Moeckel GW, Kashgarian M, Wilson FP, Parikh CR, Moledina DG. Clin J Am Soc Nephrol. 2022 Sep; 2022 Aug 10. PMID: 35948365.
• Severe AKI in a Patient on Multiple Antimicrobial Agents for Leg Infection.Rehan A, Moeckel GW, Perazella MA. Kidney360. 2022 Feb 24; 2022 Feb 24. PMID: 35373119.
• Urine interleukin-9 and tumor necrosis factor-α for prognosis of human acute interstitial nephritis.Moledina DG, Wilson FP, Kukova L, Obeid W, Luciano R, Kuperman M, Moeckel GW, Kashgarian M, Perazella MA, Cantley LG, Parikh CR. Nephrol Dial Transplant. 2021 Sep 27. PMID: 33125471.
• Tubular Cell Dropout in Preimplantation Deceased Donor Biopsies as a Predictor of Delayed Graft Function.Avigan ZM, Singh N, Kliegel JA, Weiss M, Moeckel GW, Cantley LG. Transplant Direct. 2021 Jul; 2021 Jun 18. PMID: 34476295.
• Response of the ENPP1-Deficient Skeletal Phenotype to Oral Phosphate Supplementation and/or Enzyme Replacement Therapy: Comparative Studies in Humans and Mice.Ferreira CR, Kavanagh D, Oheim R, Zimmerman K, Stürznickel J, Li X, Stabach P, Rettig RL, Calderone L, MacKichan C, Wang A, Hutchinson HA, Nelson T, Tommasini SM, von Kroge S, Fiedler IA, Lester ER, Moeckel GW, Busse B, Schinke T, Carpenter TO, Levine MA, Horowitz MC, Braddock DT. J Bone Miner Res. 2021 May; 2021 Feb 18. PMID: 33465815.
• Collagenofibrotic glomerulopathy in a kidney transplant recipient: A first report.Jdiaa SS, Moeckel GW, Kfoury HM, Medawar WA, Abu-Alfa AK. Am J Transplant. 2021 May; 2020 Dec 23. PMID: 33206467.
• PD-1H (VISTA)-mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus.Han X, Vesely MD, Yang W, Sanmamed MF, Badri T, Alawa J, López-Giráldez F, Gaule P, Lee SW, Zhang JP, Nie X, Nassar A, Boto A, Flies DB, Zheng L, Kim TK, Moeckel GW, McNiff JM, Chen L. Sci Transl Med. 2019 Dec 11. PMID: 31826980.
• Hypergranulotic dyscornification: 30 cases of a striking epithelial reaction pattern.Roy SF, Ko CJ, Moeckel GW, Mcniff JM. J Cutan Pathol. 2019 Oct; 2019 Jul 5. PMID: 31157457.
• Development of a 2-dimensional atlas of the human kidney with imaging mass cytometry.Singh N, Avigan ZM, Kliegel JA, Shuch BM, Montgomery RR, Moeckel GW, Cantley LG. JCI Insight. 2019 Jun 20; 2019 Jun 20. PMID: 31217358.
• Urine TNF-α and IL-9 for clinical diagnosis of acute interstitial nephritis.Moledina DG, Wilson FP, Pober JS, Perazella MA, Singh N, Luciano RL, Obeid W, Lin H, Kuperman M, Moeckel GW, Kashgarian M, Cantley LG, Parikh CR. JCI Insight. 2019 May 16; 2019 May 16. PMID: 31092735.
• Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease.Landau SI, Guo X, Velazquez H, Torres R, Olson E, Garcia-Milian R, Moeckel GW, Desir GV, Safirstein R. Kidney Int. 2019 Apr. PMID: 30904067.
• Update on the Native Kidney Biopsy: Core Curriculum 2019.Luciano RL, Moeckel GW. Am J Kidney Dis. 2019 Mar; 2019 Jan 17. PMID: 30661724.
• TREX1 Mutation Causing Autosomal Dominant Thrombotic Microangiopathy and CKD-A Novel Presentation.Gulati A, Bale AE, Dykas DJ, Bia MJ, Danovitch GM, Moeckel GW, Somlo S, Dahl NK. Am J Kidney Dis. 2018 Dec; 2018 Jun 22. PMID: 29941221.
• Pathologic Perspectives on Acute Tubular Injury Assessment in the Kidney Biopsy.Moeckel GW. Semin Nephrol. 2018 Jan. PMID: 29291758.
• Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI.Nakazawa D, Kumar SV, Marschner J, Desai J, Holderied A, Rath L, Kraft F, Lei Y, Fukasawa Y, Moeckel GW, Angelotti ML, Liapis H, Anders HJ. J Am Soc Nephrol. 2017 Jun; 2017 Jan 10. PMID: 28073931.
• Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney.Stankewich MC, Moeckel GW, Ji L, Ardito T, Morrow JS. PLoS One. 2016; 2016 Jan 4. PMID: 26727517.
• Antiphospholipid Antibody Syndrome: Raised Intracranial Pressure Without Cerebral Venous Sinus Thrombosis.Rudich DS, Yun SH, Liebling A, Silbert JE, Moeckel GW, Lesser RL. J Neuroophthalmol. 2015 Dec. PMID: 26049680.
• GM-CSF Promotes Macrophage Alternative Activation after Renal Ischemia/Reperfusion Injury.Huen SC, Huynh L, Marlier A, Lee Y, Moeckel GW, Cantley LG. J Am Soc Nephrol. 2015 Jun; 2014 Nov 11. PMID: 25388222.
• Quantification and localization of M2 macrophages in human kidneys with acute tubular injury.Palmer MB, Vichot AA, Cantley LG, Moeckel GW. Int J Nephrol Renovasc Dis. 2014; 2014 Nov 7. PMID: 25404860.
• Role of medullary progenitor cells in epithelial cell migration and proliferation.Chen D, Chen Z, Zhang Y, Park C, Al-Omari A, Moeckel GW. Am J Physiol Renal Physiol. 2014 Jul 1; 2014 May 7. PMID: 24808539.
• Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation.Fretz JA, Nelson T, Velazquez H, Xi Y, Moeckel GW, Horowitz MC. Kidney Int. 2014 May; 2013 Oct 30. PMID: 24172684.
• Cytomegalovirus glomerulopathy and cytomegalovirus interstitial nephritis on sequential transplant kidney biopsies.Vichot AA, Formica RN Jr, Moeckel GW. Am J Kidney Dis. 2014 Mar; 2013 Oct 25. PMID: 24568687.
• Hypertonic stress and cell death. Focus on "Multiple cell death pathways are independently activated by lethal hypertonicity in renal epithelial cells".Moeckel GW. Am J Physiol Cell Physiol. 2013 Nov 15; 2013 Sep 4. PMID: 24005043.
• Aldosterone stimulates fibronectin synthesis in renal fibroblasts through mineralocorticoid receptor-dependent and independent mechanisms.Chen D, Chen Z, Park C, Centrella M, McCarthy T, Chen L, Al-Omari A, Moeckel GW. Gene. 2013 Nov 15; 2013 Aug 30. PMID: 23994292.
• NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy.Knauf F, Asplin JR, Granja I, Schmidt IM, Moeckel GW, David RJ, Flavell RA, Aronson PS. Kidney Int. 2013 Nov; 2013 Jun 5. PMID: 23739234.
• Warfarin-related nephropathy in a patient with mild IgA nephropathy on dabigatran and aspirin.Moeckel GW, Luciano RL, Brewster UC. Clin Kidney J. 2013 Oct; 2013 Sep 10. PMID: 26120444.
• Macrophage-specific deletion of transforming growth factor-β1 does not prevent renal fibrosis after severe ischemia-reperfusion or obstructive injury.Huen SC, Moeckel GW, Cantley LG. Am J Physiol Renal Physiol. 2013 Aug 15; 2013 Jun 12. PMID: 23761668.
• Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome.Lemaire M, Frémeaux-Bacchi V, Schaefer F, Choi M, Tang WH, Le Quintrec M, Fakhouri F, Taque S, Nobili F, Martinez F, Ji W, Overton JD, Mane SM, Nürnberg G, Altmüller J, Thiele H, Morin D, Deschenes G, Baudouin V, Llanas B, Collard L, Majid MA, Simkova E, Nürnberg P, Rioux-Leclerc N, Moeckel GW, Gubler MC, Hwa J, Loirat C, Lifton RP. Nat Genet. 2013 May; 2013 Mar 31. PMID: 23542698.
• Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function.Schmidt IM, Hall IE, Kale S, Lee S, He CH, Lee Y, Chupp GL, Moeckel GW, Lee CG, Elias JA, Parikh CR, Cantley LG. J Am Soc Nephrol. 2013 Feb; 2013 Jan 4. PMID: 23291472.
• Inorganic phosphate stimulates fibronectin expression in renal fibroblasts.Chen Z, Chen D, McCarthy TL, Centrella M, Zhang Y, Moeckel GW. Cell Physiol Biochem. 2012; 2012 Jun 18. PMID: 22759963.
• Resolution of proteinuria in a patient with focal segmental glomerulosclerosis following BiPAP initiation for obesity hypoventilation syndrome.Hall IE, Kashgarian M, Moeckel GW, Dahl NK. Clin Nephrol. 2012 Jan. PMID: 22185970.
• Proteinuria and glomerular injury associated with the anti-angiogenesis drug Vargatef™.Manjunath V, Moeckel GW, Mahnensmith R, Perazella MA. NDT Plus. 2011 Dec; 2011 Jun 1. PMID: 25984216.
• Podocyte vascular endothelial growth factor (Vegf₁₆₄) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes.Veron D, Bertuccio CA, Marlier A, Reidy K, Garcia AM, Jimenez J, Velazquez H, Kashgarian M, Moeckel GW, Tufro A. Diabetologia. 2011 May; 2011 Feb 12. PMID: 21318407.
• SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function.Jurczak MJ, Lee HY, Birkenfeld AL, Jornayvaz FR, Frederick DW, Pongratz RL, Zhao X, Moeckel GW, Samuel VT, Whaley JM, Shulman GI, Kibbey RG. Diabetes. 2011 Mar. PMID: 21357472.
• Nephrotoxicity from chemotherapeutic agents: clinical manifestations, pathobiology, and prevention/therapy.Perazella MA, Moeckel GW. Semin Nephrol. 2010 Nov. PMID: 21146122.
• Hematuria and decreased kidney function as initial signs of acute B-cell lymphoblastic leukemia.Seo-Mayer P, Kenney B, McNamara J, Stein J, Moeckel GW. Am J Kidney Dis. 2010 Nov. PMID: 20599308.
• Hypertonicity-induced mitochondrial membrane permeability in renal medullary interstitial cells: protective role of osmolytes.Zhang L, Chen D, Chen Z, Moeckel GW. Cell Physiol Biochem. 2010; 2010 May 18. PMID: 20511721.
• Deletion of the Met receptor in the collecting duct decreases renal repair following ureteral obstruction.Ma H, Saenko M, Opuko A, Togawa A, Soda K, Marlier A, Moeckel GW, Cantley LG, Ishibe S. Kidney Int. 2009 Oct; 2009 Aug 12. PMID: 19675527.