Publications

2025

SUV39H1 Regulates KLF4 and Chromatin Remodeling in Smooth Muscle Cell Phenotypic Plasticity.
Chatterjee P, Chakraborty R, Sizer A, O'Brien B, Xu P, Hwa J, Xie Y, Yan Q, Hwa J, Martin K. SUV39H1 Regulates KLF4 and Chromatin Remodeling in Smooth Muscle Cell Phenotypic Plasticity. Arteriosclerosis Thrombosis And Vascular Biology 2025 PMID: 40836920, DOI: 10.1161/atvbaha.124.322179.
Peer-Reviewed Original Research
Concepts
Prostacyclin enlists AC6 to stop the clot
Martin K, Ostrom R, Hwa J. Prostacyclin enlists AC6 to stop the clot. Journal Of Thrombosis And Haemostasis 2025, 23: 2390-2392. PMID: 40738584, DOI: 10.1016/j.jtha.2025.04.008.
Peer-Reviewed Original Research
Sox17 mediates venous adaptive remodeling after arteriovenous fistula creation
Aoyagi Y, Schwartz A, Li Z, Bai H, Ho B, Lazcano-Etchebarne C, Gonzalez L, Ohashi Y, Kano M, Yatsula B, Chaar C, Martin K, Vazquez-Padron R, Dai G, Dardik A. Sox17 mediates venous adaptive remodeling after arteriovenous fistula creation. JVS Vascular Science 2025, 100392. DOI: 10.1016/j.jvssci.2025.100392.
Peer-Reviewed Original Research
Concepts
Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure
Gonzalez L, Zhang W, Bai H, Taniguchi R, Ramachandra A, Jovin D, Ohashi Y, Nguyen M, Thaxton C, Yatsula B, Vazquez-Padron R, Humphrey J, Martin K, Kyriakides T, Dardik A. Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure. AJP Heart And Circulatory Physiology 2025, 328: h1147-h1167. PMID: 40247455, PMCID: PMC12150301, DOI: 10.1152/ajpheart.00661.2024.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Changes in vascular identity during vascular remodeling
Aoyagi Y, Schwartz A, Li Z, Bai H, Gonzalez L, Etchebarne C, Ohashi Y, Kano M, Ho B, Martin K, Dardik A. Changes in vascular identity during vascular remodeling. JVS Vascular Science 2025, 6: 100282. PMID: 40213096, PMCID: PMC11985068, DOI: 10.1016/j.jvssci.2025.100282.
Peer-Reviewed Original Research
Concepts

Publications

2025

SUV39H1 Regulates KLF4 and Chromatin Remodeling in Smooth Muscle Cell Phenotypic Plasticity.

Prostacyclin enlists AC6 to stop the clot

Sox17 mediates venous adaptive remodeling after arteriovenous fistula creation

Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure

Changes in vascular identity during vascular remodeling

2024

Endothelial TGF-β Signaling Regulates Endothelial-Mesenchymal Transition During Arteriovenous Fistula Remodeling in Mice With Chronic Kidney Disease

Loss of TGFβ-Mediated Repression of Angiopoietin-2 in Pericytes Underlies Germinal Matrix Hemorrhage Pathogenesis

A Concept of “Athero-Oncology”: Tumor-Like Smooth Muscle Cells Drive Atherosclerosis

Abstract 2121: SUV39H1 Mediated Regulation Of KLF4 And KDM4a Coordinate Smooth Muscle Cell Phenotypic Plasticity

Abstract 1147: Crosstalk Between Alk5 And Mtorc1 Signaling Promotes VSMC Differentiation And The Therapeutic Effect Of Rapamycin

2023

TNFα increases the degradation of pyruvate dehydrogenase kinase 4 by the Lon protease to support proinflammatory genes

Serum Response Factor Reduces Gene Expression Noise and Confers Cell State Stability

Sex hormones impact early maturation and immune response in the arteriovenous fistula mouse model

The age of bone marrow dictates the clonality of smooth muscle-derived cells in atherosclerotic plaques

“Cre”ating New Tools for Smooth Muscle Analysis

2022

Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells

Better together

Unfolded Protein Response Differentially Modulates the Platelet Phenotype

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity

Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification

Sugar, Fat, and YAP: A Recipe for Vascular Stiffness

A guide to molecular and functional investigations of platelets to bridge basic and clinical sciences

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

2021

Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis

H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity