Lin Wang, MS
Research Associate Laboratory MedicineDownloadHi-Res Photo
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Research Associate Laboratory Medicine
Biography
Lin Wang has been a Research Associate in the Krause’s laboratory for over 20 years. She received her Master’s Degree from the University of New Haven in molecular/cellular biology. She is highly trained in molecular/cellular biology, protein biochemistry and cell culture including primary murine and human cells. Her interests outside of the laboratory include her family, gardening, hiking, backpacking, photography (including aerial photography), and volunteering for the community. She has been bagged 40 out of the 48 ‘high peaks’ in New Hampshire, and has climbed more than half of the 4000 ft peaks (total 115) in the northeastern US. Both science and nature make life fun!
Last Updated on August 12, 2026.
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Education & Training
- MS
- University of New Haven, Molecular/Cell Biology (2003)
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Lin Wang's published research.
Publications Timeline
A big-picture view of Lin Wang's research output by year.
Diane Krause, MD, PhD
Deguang Song
Emanuela Bruscia, PhD
Na Liu, PhD
Stephanie Halene, MD, Dr Med
Vanessa Scanlon, PhD
31Publications
810Citations
Publications
2026
Venetoclax Plus Hypomethylating Agents for Treatment-Naïve Myelodysplastic Syndromes with Increased Blasts: A Prospective Multicenter Cohort Study
Zhao N, Zhu L, Hu X, Tong J, Ge H, Ye L, Zhu X, Gai C, Feng Y, Wang L, Sun G, Xue L, Zhu X, Zheng C. Venetoclax Plus Hypomethylating Agents for Treatment-Naïve Myelodysplastic Syndromes with Increased Blasts: A Prospective Multicenter Cohort Study. Blood And Lymphatic Cancer Targets And Therapy 2026, 16: 592550. PMID: 42058013, PMCID: PMC13123550, DOI: 10.2147/blctt.s592550.Peer-Reviewed Original Research
2025
RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and Wnt pathway activation
Mayday M, Biancon G, Wei M, Ramirez C, Moratti I, Pintado-Urbanc A, Espinosa J, Chen M, Wang L, Simon M, Ofir-Rosenfeld Y, Rausch O, Tebaldi T, Halene S, Krause D. RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and Wnt pathway activation. Blood 2025, 146: 1096-1109. PMID: 40435410, PMCID: PMC12783520, DOI: 10.1182/blood.2024027712.Peer-Reviewed Original ResearchThis study investigates how the RBM15-MKL1 fusion protein drives acute megakaryoblastic leukemia by altering RNA methylation and activating the cancer-associated Wnt signaling pathway. The results are relevant for other forms of acute megakaryoblastic leukemia in which WNT is activated.
2024
CDK9 phosphorylates RUNX1 to promote megakaryocytic fate in megakaryocytic-erythroid progenitors
Kwon N, Lu Y, Thompson E, Mancuso R, Wang L, Zhang P, Krause D. CDK9 phosphorylates RUNX1 to promote megakaryocytic fate in megakaryocytic-erythroid progenitors. Blood 2024, 144: 1800-1812. PMID: 39102635, PMCID: PMC11530366, DOI: 10.1182/blood.2024023963.Peer-Reviewed Original ResearchThis study demonstrates that CDK9 phosphorylation of RUNX1 in human progenitors directs cell fate toward the megakaryocytic lineage and platelet production while reducing red blood cell formation.
2023
High-dose cytarabine monotherapy is superior to standard-dose cytarabine- based multiagent sequential treatment cycle for consolidation treatment in adult (14-59 years) AML patients according to European Leukemia Net 2022 risk stratification
Wang X, Liu D, Chen E, Wang L, Zhao N, Zhou L, Tong J, Xue L, Geng L, Tang B, Liu H, Liu X, Zheng C. High-dose cytarabine monotherapy is superior to standard-dose cytarabine- based multiagent sequential treatment cycle for consolidation treatment in adult (14-59 years) AML patients according to European Leukemia Net 2022 risk stratification. Frontiers In Oncology 2023, 12: 1070588. PMID: 36727072, PMCID: PMC9885085, DOI: 10.3389/fonc.2022.1070588.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization.
Reed FE, Eskow NM, Min E, Carlino M, Mancuso R, Kwon N, Smith EC, Larsuel ST, Wang L, Scanlon V, Krause DS. Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization. Haematologica 2022 PMID: 36005559.Peer-Reviewed Original ResearchStructure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization
Reed F, Eskow N, Min E, Carlino M, Mancuso R, Kwon N, Smith E, Larsuel S, Wang L, Scanlon V, Krause D. Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization. Haematologica 2022, 107: 2972-2976. PMID: 36453520, PMCID: PMC9713552, DOI: 10.3324/haematol.2021.280499.Peer-Reviewed Original ResearchCitationsAltmetricStandard-Intensity Induction and Intermediate/High-Dose Cytarabine Consolidation Can Improve Survival for Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia: A Retrospective Cohort Study
Wang L, Zhao N, Zhou L, Tong J, Xue L, Han Y, Wang X, Geng L, Tang B, Liu H, Zhu W, Cai X, Liu X, Zhu X, Sun Z, Zheng C. Standard-Intensity Induction and Intermediate/High-Dose Cytarabine Consolidation Can Improve Survival for Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia: A Retrospective Cohort Study. Clinical Interventions In Aging 2022, 17: 55-64. PMID: 35082491, PMCID: PMC8786348, DOI: 10.2147/cia.s343598.Peer-Reviewed Original ResearchCitationsAltmetric
2018
The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification
Lu YC, Sanada C, Xavier-Ferrucio J, Wang L, Zhang PX, Grimes HL, Venkatasubramanian M, Chetal K, Aronow B, Salomonis N, Krause DS. The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification. Cell Reports 2018, 25: 3229. PMID: 30540953, PMCID: PMC6357951, DOI: 10.1016/j.celrep.2018.11.075.Commentaries, Editorials and LettersCitationsAltmetricRNF186 impairs insulin sensitivity by inducing ER stress in mouse primary hepatocytes
Tong X, Zhang Q, Wang L, Ji Y, Xie L, Chen W, Zhang H. RNF186 impairs insulin sensitivity by inducing ER stress in mouse primary hepatocytes. Cellular Signalling 2018, 52: 155-162. PMID: 30223017, DOI: 10.1016/j.cellsig.2018.09.008.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsAnimalsChemokine CCL2Diabetes MellitusDiet, High-FatEndoplasmic Reticulum StressEukaryotic Initiation Factor-2BHep G2 CellsHepatocytesHumansInsulinInsulin ResistanceInterleukin-6LiverMaleMembrane ProteinsMiceMice, Inbred C57BLMice, ObeseProtein Serine-Threonine KinasesTaurochenodeoxycholic AcidTranscription Factor CHOPTumor Necrosis Factor-alphaUbiquitin-Protein LigasesSurfactant protein C dampens inflammation by decreasing JAK/STAT activation during lung repair
Jin H, Ciechanowicz AK, Kaplan AR, Wang L, Zhang P, Lu YC, Tobin RE, Tobin BA, Cohn L, Zeiss CJ, Lee PJ, Bruscia EM, Krause DS. Surfactant protein C dampens inflammation by decreasing JAK/STAT activation during lung repair. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2018, 314: l882-l892. PMID: 29345196, PMCID: PMC6008135, DOI: 10.1152/ajplung.00418.2017.Peer-Reviewed Original ResearchCitationsAltmetric
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