Next-generation molecular diagnosis: single-cell sequencing from bench to bedside
Zhu W, Zhang XY, Marjani SL, Zhang J, Zhang W, Wu S, Pan X. Next-generation molecular diagnosis: single-cell sequencing from bench to bedside. Cellular And Molecular Life Sciences 2016, 74: 869-880. PMID: 27738745, PMCID: PMC11107533, DOI: 10.1007/s00018-016-2368-x.Peer-Reviewed Original ResearchConceptsSingle-cell sequencingSingle gene disordersGenomic medicineMolecular basisCellular heterogeneityChromosomal translocationsSequencingNon-invasive prenatal diagnosisChromosome abnormalitiesTumor cellsDiagnosis/screeningCurrent progressGermlineNew biomarkersTranslocationExciting fieldAneuploidyCellsHigh-resolution studyNext generationIdentification