Featured Publications
A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity
Zhang C, Ramsey C, Berical A, Yu L, Leng L, McGinnis K, Song Y, Michael H, McCormack M, Allore H, Morris A, Crothers K, Bucala R, Lee P, Sauler M. A functional macrophage migration inhibitory factor promoter polymorphism is associated with reduced diffusing capacity. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2018, 316: l400-l405. PMID: 30520689, PMCID: PMC6397351, DOI: 10.1152/ajplung.00439.2018.Peer-Reviewed Original ResearchConceptsMacrophage migration inhibitory factorChronic obstructive pulmonary diseaseMIF -794 CATTAbnormal diffusion capacityCigarette smoke exposureSmoke exposureAssociation of MIFDiffusion capacityMacrophage migration inhibitory factor (MIF) promoter polymorphismsPathogenesis of COPDChronic cigarette smoke exposureMultivariable logistic regression modelModifiable risk factorsObstructive pulmonary diseaseMigration inhibitory factorCross-sectional analysisLogistic regression modelsCommon genetic polymorphismsInnate immune genesAirflow obstructionMIF expressionCOPD severityPulmonary diseaseMIF allelesRisk factors
2011
Pulmonary Embolism in Older Patients
Mathur A, Sauler M, Pisani M. Pulmonary Embolism in Older Patients. Respiratory Medicine 2011, 133-153. DOI: 10.1007/978-1-60761-727-3_7.ChaptersVenous thromboembolic diseaseDeep vein thrombosisPulmonary embolismThromboembolic diseaseComplications of treatmentMiddle-aged subjectsHospital deathOlder patientsVein thrombosisSignificant morbidityGeriatric populationRisk factorsMedical conditionsEmbolismPatientsDiseaseDiagnosisDeathAgeTreatmentMorbidityThrombosisComplicationsPathophysiologyMajor studies