Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans
Shigemura M, Lecuona E, Angulo M, Dada LA, Edwards MB, Welch LC, Casalino-Matsuda SM, Sporn PHS, Vadász I, Helenius IT, Nader GA, Gruenbaum Y, Sharabi K, Cummins E, Taylor C, Bharat A, Gottardi CJ, Beitel GJ, Kaminski N, Budinger GRS, Berdnikovs S, Sznajder JI. Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans. Scientific Reports 2019, 9: 18251. PMID: 31796806, PMCID: PMC6890671, DOI: 10.1038/s41598-019-54683-0.Peer-Reviewed Original ResearchConceptsLarge-scale transcriptomic studyAvailable transcriptomic datasetsCell linesWnt pathway genesOrganismal functionDrosophila melanogasterElevated CO2Different tissue originsTranscriptomic studiesBronchial cell lineCO2 elevationTranscriptomic datasetsGenomic responsesHuman bronchial cell linePathway genesGene expressionDifferent tissuesGenesHigh CO2Tissue originMammalsSkeletal musclePathwayCaenorhabditisMelanogaster