Characterization of Microrna Expression Profile In Platelets In Sickle Cell Disease
Jain S, Raghavachari N, Woodhouse K, Kaminski N, Gladwin M. Characterization of Microrna Expression Profile In Platelets In Sickle Cell Disease. Blood 2010, 116: 2030. DOI: 10.1182/blood.v116.21.2030.2030.Peer-Reviewed Original ResearchSickle cell diseasePulmonary hypertensionSCD patientsPathological platelet activationPlatelet activationCell diseaseRace-matched healthy controlsSickle cell disease patientsAfrican American control subjectsPittsburgh Medical CenterPlatelet-rich plasma samplesP-valueThromboembolic complicationsStudy enrollmentBlood InstitutePresent studyControl subjectsDisease patientsNational HeartIntravascular hemolysisHealthy controlsSCD groupSCD pathogenesisReal-time PCRIndividual patients