Jeonghyeon Moon, PhD
Postdoctoral AssociateAbout
Research
Publications
2024
Systems Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis.
Wei J, Moon J, Yasumizu Y, Zhang L, Radassi K, Buitrago-Pocasangre N, Deerhake ME, Strauli N, Chan A, Herman A, Pedotte R, Raposo C, Tackenberg B, Yim I, Pappalardo J, Longbrake EE, Sumida TS, Axisa PP, Hafler DA. Systems Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis. BioRxiv 2024 PMID: 38370778, DOI: 10.1101/2024.02.07.576204.Peer-Reviewed Original ResearchEarly immune remodeling steers clinical response to frontline chemoimmunotherapy in advanced gastric cancer.
An M, Mehta A, Min BH, Heo YJ, Wright SJ, Parikh M, Bi L, Lee H, Kim TJ, Lee SY, Moon J, Park RJ, Strickland MR, Park WY, Kang WK, Kim KM, Kim ST, Klempner SJ, Lee J. Early immune remodeling steers clinical response to frontline chemoimmunotherapy in advanced gastric cancer. Cancer Discov 2024 PMID: 38319303, DOI: 10.1158/2159-8290.CD-23-0857.Peer-Reviewed Original ResearchGut microbiome-derived butyrate inhibits the immunosuppressive factors PD-L1 and IL-10 in tumor-associated macrophages in gastric cancer.
Lee SY, Jhun J, Woo JS, Lee KH, Hwang SH, Moon J, Park G, Choi SS, Kim SJ, Jung YJ, Song KY, Cho ML. Gut microbiome-derived butyrate inhibits the immunosuppressive factors PD-L1 and IL-10 in tumor-associated macrophages in gastric cancer. Gut Microbes 2024, 16: 2300846. PMID: 38197259, DOI: 10.1080/19490976.2023.2300846.Peer-Reviewed Original Research
2023
Faecalibacterium prausnitzii alleviates inflammatory arthritis and regulates IL-17 production, short chain fatty acids, and the intestinal microbial flora in experimental mouse model for rheumatoid arthritis.
Moon J, Lee AR, Kim H, Jhun J, Lee SY, Choi JW, Jeong Y, Park MS, Ji GE, Cho ML, Park SH. Faecalibacterium prausnitzii alleviates inflammatory arthritis and regulates IL-17 production, short chain fatty acids, and the intestinal microbial flora in experimental mouse model for rheumatoid arthritis. Arthritis Res Ther 2023, 25: 130. PMID: 37496081, DOI: 10.1186/s13075-023-03118-3.Peer-Reviewed Original ResearchSmall heterodimer partner interacting leucine zipper protein (SMILE) ameliorates autoimmune arthritis via AMPK signaling pathway and the regulation of B cell activation.
Jhun J, Moon J, Kwon JY, Cho KH, Lee SY, Na HS, Cho ML, Min JK. Small heterodimer partner interacting leucine zipper protein (SMILE) ameliorates autoimmune arthritis via AMPK signaling pathway and the regulation of B cell activation. Cell Commun Signal 2023, 21: 98. PMID: 37143079, DOI: 10.1186/s12964-023-01054-y.Peer-Reviewed Original ResearchPrognostic significances of PD-L1- and CTLA-4-positive T cells and positive correlations of immunosuppressive marker expression between cancer tissue and peripheral blood in patients with gastric cancer.
Lee KH, Kim SJ, Woo JS, Lee SY, Jhun J, Moon J, Jung YJ, Cho ML, Song KY. Prognostic significances of PD-L1- and CTLA-4-positive T cells and positive correlations of immunosuppressive marker expression between cancer tissue and peripheral blood in patients with gastric cancer. Front Immunol 2023, 14: 1138743. PMID: 37153541, DOI: 10.3389/fimmu.2023.1138743.Peer-Reviewed Original Research
2022
Rebamipide treatment ameliorates obesity phenotype by regulation of immune cells and adipocytes.
Jhun J, Moon J, Kim SY, Cho KH, Na HS, Choi J, Jung YJ, Song KY, Min JK, Cho ML. Rebamipide treatment ameliorates obesity phenotype by regulation of immune cells and adipocytes. PLoS One 2022, 17: e0277692. PMID: 36574392, DOI: 10.1371/journal.pone.0277692.Peer-Reviewed Original ResearchEzetimibe ameliorates clinical symptoms in a mouse model of ankylosing spondylitis associated with suppression of Th17 differentiation.
Moon J, Lee SY, Na HS, Lee AR, Cho KH, Choi JW, Park SH, Cho ML. Ezetimibe ameliorates clinical symptoms in a mouse model of ankylosing spondylitis associated with suppression of Th17 differentiation. Front Immunol 2022, 13: 922531. PMID: 36059546, DOI: 10.3389/fimmu.2022.922531.Peer-Reviewed Original ResearchEarly Tumor-Immune Microenvironmental Remodeling and Response to First-Line Fluoropyrimidine and Platinum Chemotherapy in Advanced Gastric Cancer.
Kim R, An M, Lee H, Mehta A, Heo YJ, Kim KM, Lee SY, Moon J, Kim ST, Min BH, Kim TJ, Rha SY, Kang WK, Park WY, Klempner SJ, Lee J. Early Tumor-Immune Microenvironmental Remodeling and Response to First-Line Fluoropyrimidine and Platinum Chemotherapy in Advanced Gastric Cancer. Cancer Discov 2022, 12: 984-1001. PMID: 34933901, DOI: 10.1158/2159-8290.CD-21-0888.Peer-Reviewed Original Research
2021
Expanded IL-22(+) Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with Dyslipidaemia.
Min HK, Moon J, Lee SY, Lee AR, Lee CR, Lee J, Kwok SK, Cho ML, Park SH. Expanded IL-22(+) Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with Dyslipidaemia. Immune Netw 2021, 21: e43. PMID: 35036030, DOI: 10.4110/in.2021.21.e43.Peer-Reviewed Original Research