2001
Enhanced B7 Costimulatory Molecule Expression In Inflammatory Human Sural Nerve Biopsies
Kiefer R, Dangond F, Mueller M, Toyka K, Hafler D, Hartung H. Enhanced B7 Costimulatory Molecule Expression In Inflammatory Human Sural Nerve Biopsies. Journal Of The Peripheral Nervous System 2001, 6: 64-64. DOI: 10.1046/j.1529-8027.2001.01008-15.x.Peer-Reviewed Original ResearchChronic inflammatory demyelinating polyneuropathyGuillain-Barre syndromeSural nerve biopsyPeripheral nervous systemB7-1Nerve biopsyB7-2 mRNAPolymerase chain reactionB7-2Nervous systemCases of GBSCostimulatory molecules B7-1Th-2 phenotypeInflammatory demyelinating polyneuropathyB7-1 proteinCostimulatory molecule expressionT cell responsesEffective antigen presentationCases of neuroborreliosisHuman sural nerve biopsiesCIDP casesCIDP variantsDemyelinating polyneuropathyEndoneurial macrophagesDisease course
2000
Enhanced B7 costimulatory molecule expression in inflammatory human sural nerve biopsies
Kiefer R, Dangond F, Mueller M, Toyka KV, Hafler DA, Hartung HP. Enhanced B7 costimulatory molecule expression in inflammatory human sural nerve biopsies. Journal Of Neurology Neurosurgery & Psychiatry 2000, 69: 362. PMID: 10945811, PMCID: PMC1737105, DOI: 10.1136/jnnp.69.3.362.Peer-Reviewed Original ResearchConceptsChronic inflammatory demyelinating polyneuropathyGuillain-Barré syndromeSural nerve biopsyPeripheral nervous systemB7-1Nerve biopsyB7-2 mRNAB7 moleculesPolymerase chain reactionB7-2Nervous systemCases of GBSNon-inflammatory control groupCostimulatory molecules B7-1B7-1 mRNANon-inflammatory controlsTh-2 phenotypeInflammatory demyelinating polyneuropathyB7-1 proteinCostimulatory molecule expressionT cell responsesEffective antigen presentationCases of neuroborreliosisHuman sural nerve biopsiesCIDP cases
1992
Autoreactive T Cells in Multiple Sclerosis
Zhang J, Weiner H, Hafler D. Autoreactive T Cells in Multiple Sclerosis. International Reviews Of Immunology 1992, 9: 183-201. PMID: 1285060, DOI: 10.3109/08830189209061790.Peer-Reviewed Original ResearchConceptsCentral nervous systemMultiple sclerosisInflammatory processT cellsCerebrospinal fluidNervous systemAcute MS plaquesActive inflammatory processAutoreactive T cellsChronic inflammatory diseaseCNS inflammatory processesIL-2 receptorPeripheral nervous systemActivated T cellsNeurologic disabilityNeurological functionMS plaquesSensory deficitsInflammatory diseasesOligoclonal immunoglobulinsPositive macrophagesT lymphocytesWhite matterVisual problemsDemyelination