2012
The Impact of Differential Regulation on Bacterial Speciation
Groisman E. The Impact of Differential Regulation on Bacterial Speciation. 2012, 109-114. DOI: 10.1128/9781555818470.ch15.Peer-Reviewed Original ResearchBacterial speciesGene regulatory strategiesRelated bacterial speciesResistance proteinAmino acid sequenceEukaryotic speciesRelated speciesBacterial speciationRelated organismsIndividual speciesRegulatory proteinsAcid sequenceBacterial behaviorEnteric speciesGenetic differencesGenetic scenariosDifferential regulationResistance genesEscherichia coliSpeciesEconomic importanceProteinSalmonella entericaFamily EnterobacteriaceaeOrganisms
2005
The origin and evolution of human pathogens
Groisman EA, Casadesús J. The origin and evolution of human pathogens. Molecular Microbiology 2005, 56: 1-7. PMID: 15773974, DOI: 10.1111/j.1365-2958.2005.04564.x.Peer-Reviewed Original ResearchConceptsCreation of genesNon-host environmentsHuman pathogensRelated bacterial speciesCertain pathogensORFan genesHomologous genesCell surface modificationExpression of productsHousekeeping functionsRelated membersHost rangeColonization processTissue specificityPathogenicity islandSequence databasesCertain lociBacterial speciesGenesCell surfaceDisparate regulationGenetic originBacterial pathogensNew functionsGene variationTranscriptional Regulation of the 4-Amino-4-deoxy-L-arabinose Biosynthetic Genes in Yersinia pestis *
Winfield MD, Latifi T, Groisman EA. Transcriptional Regulation of the 4-Amino-4-deoxy-L-arabinose Biosynthetic Genes in Yersinia pestis *. Journal Of Biological Chemistry 2005, 280: 14765-14772. PMID: 15710615, DOI: 10.1074/jbc.m413900200.Peer-Reviewed Original ResearchMeSH KeywordsAmino SugarsBacterial ProteinsBase SequenceBinding SitesCell ProliferationDeoxyribonuclease IDNA PrimersGene DeletionGene Expression Regulation, BacterialIronLipid AMagnesiumModels, BiologicalMolecular Sequence DataPlasmidsPolymyxin BPromoter Regions, GeneticSalmonella entericaSingle-Strand Specific DNA and RNA EndonucleasesTranscription FactorsTranscription, GeneticYersinia pestisConceptsPmrD proteinBiosynthetic genesPhoP/PhoQ systemTwo-component regulatory systemTranscription of PmrADisparate regulatory pathwaysYersinia pestisRelated bacterial speciesPmrA/PmrBSalmonella enterica serovar TyphimuriumPmrA proteinPhoP proteinGram-negative bacteriaTranscriptional regulationUgd geneMembrane remodelingEnterica serovar TyphimuriumRegulatory pathwaysCationic antimicrobial peptidesDistinct binding sitesBacterial membranesBacterial speciesDifferent promotersGenesPmrB protein
1999
A Periplasmicd-Alanyl-d-Alanine Dipeptidase in the Gram-Negative Bacterium Salmonella enterica
Hilbert F, del Portillo F, Groisman E. A Periplasmicd-Alanyl-d-Alanine Dipeptidase in the Gram-Negative Bacterium Salmonella enterica. Journal Of Bacteriology 1999, 181: 2158-2165. PMID: 10094694, PMCID: PMC93629, DOI: 10.1128/jb.181.7.2158-2165.1999.Peer-Reviewed Original ResearchConceptsD-alanyl-D-alanine dipeptidaseD-Ala-D-Ala dipeptidaseHorizontal gene transferRelated bacterial speciesSpecies Salmonella entericaEscherichia coli KSimilar substrate specificityBacterium Salmonella entericaSalmonella entericaDipeptidase geneWild-type SalmonellaPeptidoglycan metabolismSole carbon sourcePeriplasmic spaceSalmonella chromosomeSubstrate specificityD-AlaColi KBacterial speciesSalmonella enzymeVanX proteinGene transferEnzymatic activityGlycopeptide antibiotic vancomycinCarbon source