Recent Publications

• Exploring Calcium Channels as Potential Therapeutic Targets in Blast Traumatic Brain Injury.Wachtler N, O'Brien R, Ehrlich BE, McGuone D. Pharmaceuticals (Basel). 2025 Feb 6; 2025 Feb 6. PMID: 40006037.
• Corrigendum to "Modulating TRPV4 channels with paclitaxel and lithium" [Cell Calcium 91 (2020) 102266].Sánchez JC, Muñoz LV, Ehrlich BE. Cell Calcium. 2025 Jan; 2025 Jan 1. PMID: 39746287.
• Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis.Ogino N, Leite MF, Guerra MT, Kruglov E, Asashima H, Hafler DA, Ito T, Pereira JP, Peiffer BJ, Sun Z, Ehrlich BE, Nathanson MH. J Clin Invest. 2024 Jun 25; 2024 Jun 25. PMID: 38916955.
• NCS-1 protein regulates TRPA1 channel through the PI3K pathway in breast cancer and neuronal cells.Sánchez JC, Alemán A, Henao JF, Olaya JC, Ehrlich BE. J Physiol Biochem. 2024 May; 2024 Apr 2. PMID: 38564162.
• Response to Kochan et al., 2023.Ehrlich BE, Vahdat L, DeCillis AP, Seidman A. Support Care Cancer. 2023 Jul 22; 2023 Jul 22. PMID: 37480366.
• Calcium signaling in chemotherapy-induced neuropathy.Fonseca MC, Marazzi-Diniz PHS, Leite MF, Ehrlich BE. Cell Calcium. 2023 Jul; 2023 May 20. PMID: 37244172.
• Location, location, and activation of a channel by calcium.Kuo IY, Ehrlich BE. Proc Natl Acad Sci U S A. 2022 Oct 25; 2022 Oct 10. PMID: 36215521.
• A preliminary, prospective study of peripheral neuropathy and cognitive function in patients with breast cancer during taxane therapy.Ibrahim EY, Munshani S, Domenicano I, Rodwin R, Nowak RJ, Pusztai L, Lustberg M, Ehrlich BE. PLoS One. 2022; 2022 Oct 7. PMID: 36206298.
• Boosting ER-mitochondria calcium transfer to treat Wolfram syndrome.Fischer TT, Nguyen LD, Ehrlich BE. Cell Calcium. 2022 Jun; 2022 Mar 24. PMID: 35366518.
• Biomarkers of Chemotherapy-Induced Peripheral Neuropathy: Current Status and Future Directions.Rodwin RL, Siddiq NZ, Ehrlich BE, Lustberg MB. Front Pain Res (Lausanne). 2022; 2022 Mar 14. PMID: 35360655.
• Cytoskeletal dynamics regulates stromal invasion behavior of distinct liver cancer subtypes.Nguyen RY, Xiao H, Gong X, Arroyo A, Cabral AT, Fischer TT, Flores KM, Zhang X, Robert ME, Ehrlich BE, Mak M. Commun Biol. 2022 Mar 3; 2022 Mar 3. PMID: 35241781.
• The Impact of Mutations in Wolframin on Psychiatric Disorders.Munshani S, Ibrahim EY, Domenicano I, Ehrlich BE. Front Pediatr. 2021; 2021 Oct 21. PMID: 34746052.
• Neuronal calcium sensor 1 (NCS1) dependent modulation of neuronal morphology and development.Fischer TT, Nguyen LD, Ehrlich BE. FASEB J. 2021 Oct. PMID: 34499766.
• Functional Interaction between Transient Receptor Potential V4 Channel and Neuronal Calcium Sensor 1 and the Effects of Paclitaxel.Sánchez JC, Ehrlich BE. Mol Pharmacol. 2021 Sep; 2021 Jul 28. PMID: 34321341.
• Pharmacological rescue of cognitive function in a mouse model of chemobrain.Nguyen LD, Fischer TT, Ehrlich BE. Mol Neurodegener. 2021 Jun 26; 2021 Jun 26. PMID: 34174909.
• Cognitive Effects and Depression Associated With Taxane-Based Chemotherapy in Breast Cancer Survivors: A Meta-Analysis.Ibrahim EY, Domenicano I, Nyhan K, Elfil M, Mougalian SS, Cartmel B, Ehrlich BE. Front Oncol. 2021; 2021 Apr 29. PMID: 33996556.
• BOK controls apoptosis by Ca(2+) transfer through ER-mitochondrial contact sites.Carpio MA, Means RE, Brill AL, Sainz A, Ehrlich BE, Katz SG. Cell Rep. 2021 Mar 9. PMID: 33691099.
• Comprehensive somatosensory and neurological phenotyping of NCS1 knockout mice.Nguyen LD, Nolte LG, Tan WJT, Giuvelis D, Santos-Sacchi J, Bilsky E, Ehrlich BE. Sci Rep. 2021 Jan 27; 2021 Jan 27. PMID: 33504822.
• Modulating TRPV4 channels with paclitaxel and lithium.Sánchez JC, Muñoz LV, Ehrlich BE. Cell Calcium. 2020 Nov; 2020 Aug 18. PMID: 32871457.
• Wolfram Syndrome: a Monogenic Model to Study Diabetes Mellitus and Neurodegeneration.Fischer TT, Ehrlich BE. Curr Opin Physiol. 2020 Oct; 2020 Jul 15. PMID: 32864536.
• Calpain inhibitor and ibudilast rescue β cell functions in a cellular model of Wolfram syndrome.Nguyen LD, Fischer TT, Abreu D, Arroyo A, Urano F, Ehrlich BE. Proc Natl Acad Sci U S A. 2020 Jul 21; 2020 Jul 6. PMID: 32632005.
• Cellular mechanisms and treatments for chemobrain: insight from aging and neurodegenerative diseases.Nguyen LD, Ehrlich BE. EMBO Mol Med. 2020 Jun 8; 2020 Apr 29. PMID: 32346964.
• Contractile work directly modulates mitochondrial protein levels in human engineered heart tissues.Ng R, Sewanan LR, Brill AL, Stankey P, Li X, Qyang Y, Ehrlich BE, Campbell SG. Am J Physiol Heart Circ Physiol. 2020 Jun 1; 2020 May 8. PMID: 32383992.
• Neuronal Calcium Sensor 1 is up-regulated in response to stress to promote cell survival and motility in cancer cells.Grosshans HK, Fischer TT, Steinle JA, Brill AL, Ehrlich BE. Mol Oncol. 2020 Jun; 2020 Apr 28. PMID: 32239615.
• Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis.Perry RJ, Zhang D, Guerra MT, Brill AL, Goedeke L, Nasiri AR, Rabin-Court A, Wang Y, Peng L, Dufour S, Zhang Y, Zhang XM, Butrico GM, Toussaint K, Nozaki Y, Cline GW, Petersen KF, Nathanson MH, Ehrlich BE, Shulman GI. Nature. 2020 Mar; 2020 Mar 4. PMID: 32132708.
• Polycystin 2: A calcium channel, channel partner, and regulator of calcium homeostasis in ADPKD.Brill AL, Ehrlich BE. Cell Signal. 2020 Feb; 2019 Dec 2. PMID: 31805375.
• Polycystin 2 is increased in disease to protect against stress-induced cell death.Brill AL, Fischer TT, Walters JM, Marlier A, Sewanan LR, Wilson PC, Johnson EK, Moeckel G, Cantley LG, Campbell SG, Nerbonne JM, Chung HJ, Robert ME, Ehrlich BE. Sci Rep. 2020 Jan 15; 2020 Jan 15. PMID: 31941974.
• Prevention of chemotherapy-induced peripheral neuropathy: A review of recent findings.Ibrahim EY, Ehrlich BE. Crit Rev Oncol Hematol. 2020 Jan; 2019 Nov 13. PMID: 31783290.
• Characterization of NCS1-InsP3R1 interaction and its functional significance.Nguyen LD, Petri ET, Huynh LK, Ehrlich BE. J Biol Chem. 2019 Dec 6; 2019 Oct 28. PMID: 31659121.
• O-GlcNAc transferase suppresses necroptosis and liver fibrosis.Zhang B, Li MD, Yin R, Liu Y, Yang Y, Mitchell-Richards KA, Nam JH, Li R, Wang L, Iwakiri Y, Chung D, Robert ME, Ehrlich BE, Bennett AM, Yu J, Nathanson MH, Yang X. JCI Insight. 2019 Nov 1; 2019 Nov 1. PMID: 31672932.
• Polycystin 2 regulates mitochondrial Ca(2+) signaling, bioenergetics, and dynamics through mitofusin 2.Kuo IY, Brill AL, Lemos FO, Jiang JY, Falcone JL, Kimmerling EP, Cai Y, Dong K, Kaplan DL, Wallace DP, Hofer AM, Ehrlich BE. Sci Signal. 2019 May 7; 2019 May 7. PMID: 31064883.
• TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells.Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A. Nat Commun. 2019 May 2; 2019 May 2. PMID: 31048699.
• Neuronal calcium sensor 1 (NCS1) promotes motility and metastatic spread of breast cancer cells in vitro and in vivo.Apasu JE, Schuette D, LaRanger R, Steinle JA, Nguyen LD, Grosshans HK, Zhang M, Cai WL, Yan Q, Robert ME, Mak M, Ehrlich BE. FASEB J. 2019 Apr; 2018 Dec 28. PMID: 30592625.
• NCS-1 is a regulator of calcium signaling in health and disease.Boeckel GR, Ehrlich BE. Biochim Biophys Acta Mol Cell Res. 2018 Nov; 2018 May 8. PMID: 29746899.
• Hepatocellular Carcinoma Outcome Is Predicted by Expression of Neuronal Calcium Sensor 1.Schuette D, Moore LM, Robert ME, Taddei TH, Ehrlich BE. Cancer Epidemiol Biomarkers Prev. 2018 Sep; 2018 May 22. PMID: 29789326.
• An assessment of neuronal calcium sensor-1 and response to neoadjuvant chemotherapy in breast cancer patients.Moore LM, Wilkinson R, Altan M, Toki M, Carvajal-Hausdorf DE, McGuire J, Ehrlich BE, Rimm DL. NPJ Breast Cancer. 2018; 2018 Mar 12. PMID: 29560416.
• The prevention of chemotherapy induced peripheral neuropathy by concurrent treatment with drugs used for bipolar disease: a retrospective chart analysis in human cancer patients.Wadia RJ, Stolar M, Grens C, Ehrlich BE, Chao HH. Oncotarget. 2018 Jan 26; 2017 Dec 19. PMID: 29484113.
• Polycystin and calcium signaling in cell death and survival.Lemos FO, Ehrlich BE. Cell Calcium. 2018 Jan; 2017 May 24. PMID: 28601384.
• Polycystin 2-dependent cardio-protective mechanisms revealed by cardiac stress.Giehl E, Lemos FO, Huang Y, Giordano FJ, Kuo IY, Ehrlich BE. Pflugers Arch. 2017 Nov; 2017 Jul 31. PMID: 28762163.
• Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation.Ruan HB, Ma Y, Torres S, Zhang B, Feriod C, Heck RM, Qian K, Fu M, Li X, Nathanson MH, Bennett AM, Nie Y, Ehrlich BE, Yang X. Genes Dev. 2017 Aug 15; 2017 Sep 13. PMID: 28903979.
• Calcium Sensor, NCS-1, Promotes Tumor Aggressiveness and Predicts Patient Survival.Moore LM, England A, Ehrlich BE, Rimm DL. Mol Cancer Res. 2017 Jul; 2017 Mar 8. PMID: 28275088.
• Hepatic Inositol 1,4,5 Trisphosphate Receptor Type 1 Mediates Fatty Liver.Feriod CN, Oliveira AG, Guerra MT, Nguyen L, Richards KM, Jurczak MJ, Ruan HB, Camporez JP, Yang X, Shulman GI, Bennett AM, Nathanson MH, Ehrlich BE. Hepatol Commun. 2017 Feb; 2016 Nov 11. PMID: 28966992.
• The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function.Padovano V, Kuo IY, Stavola LK, Aerni HR, Flaherty BJ, Chapin HC, Ma M, Somlo S, Boletta A, Ehrlich BE, Rinehart J, Caplan MJ. Mol Biol Cell. 2017 Jan 15; 2016 Nov 23. PMID: 27881662.
• Low-dose dasatinib rescues cardiac function in Noonan syndrome.Yi JS, Huang Y, Kwaczala AT, Kuo IY, Ehrlich BE, Campbell SG, Giordano FJ, Bennett AM. JCI Insight. 2016 Dec 8; 2016 Dec 8. PMID: 27942593.
• Neuronal Calcium Sensor 1 Has Two Variants with Distinct Calcium Binding Characteristics.Wang B, Boeckel GR, Huynh L, Nguyen L, Cao W, De La Cruz EM, Kaftan EJ, Ehrlich BE. PLoS One. 2016; 2016 Aug 30. PMID: 27575489.
• Structural studies of the C-terminal tail of polycystin-2 (PC2) reveal insights into the mechanisms used for the functional regulation of PC2.Yang Y, Ehrlich BE. J Physiol. 2016 Aug 1; 2016 Apr 27. PMID: 26857659.
• Decreased Polycystin 2 Levels Result in Non-Renal Cardiac Dysfunction with Aging.Kuo IY, Duong SL, Nguyen L, Ehrlich BE. PLoS One. 2016; 2016 Apr 15. PMID: 27081851.
• Conformational dynamics of Ca2+-dependent responses in the polycystin-2 C-terminal tail.Yang Y, Hodsdon ME, Lolis EJ, Ehrlich BE. Biochem J. 2016 Feb 1; 2015 Nov 16. PMID: 26574436.
• Oligomerization of the polycystin-2 C-terminal tail and effects on its Ca2+-binding properties.Yang Y, Keeler C, Kuo IY, Lolis EJ, Ehrlich BE, Hodsdon ME. J Biol Chem. 2015 Apr 17; 2015 Feb 25. PMID: 25716316.
• The effects of mycoplasma contamination upon the ability to form bioengineered 3D kidney cysts.DesRochers TM, Kuo IY, Kimmerling EP, Ehrlich BE, Kaplan DL. PLoS One. 2015; 2015 Mar 20. PMID: 25793639.
• Presenilin-like GxGD membrane proteases have dual roles as proteolytic enzymes and ion channels.Kuo IY, Hu J, Ha Y, Ehrlich BE. J Biol Chem. 2015 Mar 6; 2015 Jan 21. PMID: 25609250.
• Signaling in muscle contraction.Kuo IY, Ehrlich BE. Cold Spring Harb Perspect Biol. 2015 Feb 2; 2015 Feb 2. PMID: 25646377.
• Muscling in on the ryanodine receptor.Kuo IY, Ehrlich BE. Nat Struct Mol Biol. 2015 Feb. PMID: 25650905.
• Inositol 1,4,5-trisphosphate receptor type II (InsP3R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP3R-II.Feriod CN, Nguyen L, Jurczak MJ, Kruglov EA, Nathanson MH, Shulman GI, Bennett AM, Ehrlich BE. Am J Physiol Endocrinol Metab. 2014 Dec 1; 2014 Oct 14. PMID: 25315698.
• Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways.Kuo IY, Kwaczala AT, Nguyen L, Russell KS, Campbell SG, Ehrlich BE. Proc Natl Acad Sci U S A. 2014 Nov 18; 2014 Nov 3. PMID: 25368166.
• Cyst formation following disruption of intracellular calcium signaling.Kuo IY, DesRochers TM, Kimmerling EP, Nguyen L, Ehrlich BE, Kaplan DL. Proc Natl Acad Sci U S A. 2014 Sep 30; 2014 Sep 16. PMID: 25228769.
• The number and location of EF hand motifs dictates the calcium dependence of polycystin-2 function.Kuo IY, Keeler C, Corbin R, Ćelić A, Petri ET, Hodsdon ME, Ehrlich BE. FASEB J. 2014 May; 2014 Feb 20. PMID: 24558196.
• An explicit formulation approach for the analysis of calcium binding to EF-hand proteins using isothermal titration calorimetry.Keeler C, Poon G, Kuo IY, Ehrlich BE, Hodsdon ME. Biophys J. 2013 Dec 17. PMID: 24359756.
• The role of chromogranin B in an animal model of multiple sclerosis.Mo M, Hoang HT, Schmidt S, Clark RB, Ehrlich BE. Mol Cell Neurosci. 2013 Sep; 2013 Apr 24. PMID: 23624073.
• Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy.Paavola J, Schliffke S, Rossetti S, Kuo IY, Yuan S, Sun Z, Harris PC, Torres VE, Ehrlich BE. J Mol Cell Cardiol. 2013 May; 2013 Jan 30. PMID: 23376035.
• Ion channels in renal disease.Kuo IY, Ehrlich BE. Chem Rev. 2012 Dec 12; 2012 Jul 18. PMID: 22809040.
• Prevention of paclitaxel-induced peripheral neuropathy by lithium pretreatment.Mo M, Erdelyi I, Szigeti-Buck K, Benbow JH, Ehrlich BE. FASEB J. 2012 Nov; 2012 Aug 13. PMID: 22889832.
• Calcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating.Ćelić AS, Petri ET, Benbow J, Hodsdon ME, Ehrlich BE, Boggon TJ. J Biol Chem. 2012 May 18; 2012 Apr 3. PMID: 22474326.
• Derivation of functional ventricular cardiomyocytes using endogenous promoter sequence from murine embryonic stem cells.Lee MY, Sun B, Schliffke S, Yue Z, Ye M, Paavola J, Bozkulak EC, Amos PJ, Ren Y, Ju R, Jung YW, Ge X, Yue L, Ehrlich BE, Qyang Y. Stem Cell Res. 2012 Jan; 2011 Aug 22. PMID: 22099020.
• C-terminal domain of chromogranin B regulates intracellular calcium signaling.Schmidt S, Mo M, Heidrich FM, Ćelić A, Ehrlich BE. J Biol Chem. 2011 Dec 30; 2011 Oct 20. PMID: 22016391.
• High density cultures of embryoid bodies enhanced cardiac differentiation of murine embryonic stem cells.Lee MY, Cagavi Bozkulak E, Schliffke S, Amos PJ, Ren Y, Ge X, Ehrlich BE, Qyang Y. Biochem Biophys Res Commun. 2011 Dec 9; 2011 Nov 6. PMID: 22079290.
• Protection of neuronal calcium sensor 1 protein in cells treated with paclitaxel.Benbow JH, DeGray B, Ehrlich BE. J Biol Chem. 2011 Oct 7; 2011 Aug 1. PMID: 21808066.
• Small molecule Wnt inhibitors enhance the efficiency of BMP-4-directed cardiac differentiation of human pluripotent stem cells.Ren Y, Lee MY, Schliffke S, Paavola J, Amos PJ, Ge X, Ye M, Zhu S, Senyei G, Lum L, Ehrlich BE, Qyang Y. J Mol Cell Cardiol. 2011 Sep; 2011 May 4. PMID: 21569778.
• Prolonged oxaliplatin exposure alters intracellular calcium signaling: a new mechanism to explain oxaliplatin-associated peripheral neuropathy.Schulze C, McGowan M, Jordt SE, Ehrlich BE. Clin Colorectal Cancer. 2011 Jun; 2011 Apr 22. PMID: 21859566.
• Isoform-specific regulation of the inositol 1,4,5-trisphosphate receptor by O-linked glycosylation.Bimboese P, Gibson CJ, Schmidt S, Xiang W, Ehrlich BE. J Biol Chem. 2011 May 6; 2011 Mar 7. PMID: 21383013.
• Paclitaxel accelerates spontaneous calcium oscillations in cardiomyocytes by interacting with NCS-1 and the InsP3R.Zhang K, Heidrich FM, DeGray B, Boehmerle W, Ehrlich BE. J Mol Cell Cardiol. 2010 Nov; 2010 Aug 27. PMID: 20801127.
• Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity.Petri ET, Celic A, Kennedy SD, Ehrlich BE, Boggon TJ, Hodsdon ME. Proc Natl Acad Sci U S A. 2010 May 18; 2010 May 3. PMID: 20439752.
• Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2.Casuscelli J, Schmidt S, DeGray B, Petri ET, Celić A, Folta-Stogniew E, Ehrlich BE, Boggon TJ. Am J Physiol Renal Physiol. 2009 Nov; 2009 Sep 2. PMID: 19726544.
• Discrete proteolysis of neuronal calcium sensor-1 (NCS-1) by mu-calpain disrupts calcium binding.Blachford C, Celić A, Petri ET, Ehrlich BE. Cell Calcium. 2009 Oct; 2009 Sep 3. PMID: 19732951.
• Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis.Celić A, Petri ET, Demeler B, Ehrlich BE, Boggon TJ. J Biol Chem. 2008 Oct 17; 2008 Aug 11. PMID: 18694932.
• Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.Geng L, Boehmerle W, Maeda Y, Okuhara DY, Tian X, Yu Z, Choe CU, Anyatonwu GI, Ehrlich BE, Somlo S. Proc Natl Acad Sci U S A. 2008 Oct 14; 2008 Oct 3. PMID: 18836075.
• Chromogranin B regulates calcium signaling, nuclear factor kappaB activity, and brain natriuretic peptide production in cardiomyocytes.Heidrich FM, Zhang K, Estrada M, Huang Y, Giordano FJ, Ehrlich BE. Circ Res. 2008 May 23; 2008 Apr 17. PMID: 18420944.
• Inositol 1,4,5-trisphosphate receptor movement is restricted by addition of elevated levels of O-linked sugar.Gibson CJ, Ehrlich BE. Cell Calcium. 2008 Mar; 2007 Jul 3. PMID: 17610951.
• Regulation of the inositol 1,4,5-trisphosphate receptor type I by O-GlcNAc glycosylation.Rengifo J, Gibson CJ, Winkler E, Collin T, Ehrlich BE. J Neurosci. 2007 Dec 12. PMID: 18077693.
• Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile.Minagawa N, Nagata J, Shibao K, Masyuk AI, Gomes DA, Rodrigues MA, Lesage G, Akiba Y, Kaunitz JD, Ehrlich BE, Larusso NF, Nathanson MH. Gastroenterology. 2007 Nov; 2007 Aug 14. PMID: 17916355.
• Inositol 1,4,5 trisphosphate receptor and chromogranin B are concentrated in different regions of the hippocampus.Nicolay NH, Hertle D, Boehmerle W, Heidrich FM, Yeckel M, Ehrlich BE. J Neurosci Res. 2007 Jul. PMID: 17471556.
• Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation.Boehmerle W, Zhang K, Sivula M, Heidrich FM, Lee Y, Jordt SE, Ehrlich BE. Proc Natl Acad Sci U S A. 2007 Jun 26; 2007 Jun 20. PMID: 17581879.
• Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2.Anyatonwu GI, Estrada M, Tian X, Somlo S, Ehrlich BE. Proc Natl Acad Sci U S A. 2007 Apr 10; 2007 Apr 2. PMID: 17404231.
• TRP channels in disease.Jordt SE, Ehrlich BE. Subcell Biochem. 2007. PMID: 18193640.
• The inositol 1,4,5-trisphosphate receptor (IP3R) and its regulators: sometimes good and sometimes bad teamwork.Choe CU, Ehrlich BE. Sci STKE. 2006 Nov 28; 2006 Nov 28. PMID: 17132820.
• Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism.Boehmerle W, Splittgerber U, Lazarus MB, McKenzie KM, Johnston DG, Austin DJ, Ehrlich BE. Proc Natl Acad Sci U S A. 2006 Nov 28; 2006 Nov 17. PMID: 17114292.
• Elevated testosterone induces apoptosis in neuronal cells.Estrada M, Varshney A, Ehrlich BE. J Biol Chem. 2006 Sep 1; 2006 Jun 27. PMID: 16803879.
• Calcium signaling in cholangiocytes.Minagawa N, Ehrlich BE, Nathanson MH. World J Gastroenterol. 2006 Jun 14. PMID: 16773703.
• Neuronal calcium sensor-1 enhancement of InsP3 receptor activity is inhibited by therapeutic levels of lithium.Schlecker C, Boehmerle W, Jeromin A, DeGray B, Varshney A, Sharma Y, Szigeti-Buck K, Ehrlich BE. J Clin Invest. 2006 Jun; 2006 May 11. PMID: 16691292.
• Ca2+ oscillations induced by testosterone enhance neurite outgrowth.Estrada M, Uhlen P, Ehrlich BE. J Cell Sci. 2006 Feb 15; 2006 Jan 31. PMID: 16449326.
• Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling.Uhlén P, Burch PM, Zito CI, Estrada M, Ehrlich BE, Bennett AM. Proc Natl Acad Sci U S A. 2006 Feb 14; 2006 Feb 3. PMID: 16461457.
• Calcium release from ryanodine receptors in the nucleoplasmic reticulum.Marius P, Guerra MT, Nathanson MH, Ehrlich BE, Leite MF. Cell Calcium. 2006 Jan; 2005 Nov 9. PMID: 16289270.
• Organic cation permeation through the channel formed by polycystin-2.Anyatonwu GI, Ehrlich BE. J Biol Chem. 2005 Aug 19; 2005 Jun 16. PMID: 15961385.
• Naive CD4+ T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation.Zielinski CE, Jacob SN, Bouzahzah F, Ehrlich BE, Craft J. J Immunol. 2005 Apr 15. PMID: 15814741.
• Signaling microdomains regulate inositol 1,4,5-trisphosphate-mediated intracellular calcium transients in cultured neurons.Jacob SN, Choe CU, Uhlen P, DeGray B, Yeckel MF, Ehrlich BE. J Neurosci. 2005 Mar 16. PMID: 15772345.
• Calcium signaling and polycystin-2.Anyatonwu GI, Ehrlich BE. Biochem Biophys Res Commun. 2004 Oct 1. PMID: 15336985.
• InsP3-mediated intracellular calcium signalling is altered by expression of synaptojanin-1.Johenning FW, Wenk MR, Uhlén P, Degray B, Lee E, De Camilli P, Ehrlich BE. Biochem J. 2004 Sep 1. PMID: 15080793.
• Functional coupling of chromogranin with the inositol 1,4,5-trisphosphate receptor shapes calcium signaling.Choe CU, Harrison KD, Grant W, Ehrlich BE. J Biol Chem. 2004 Aug 20; 2004 Jun 11. PMID: 15194698.
• Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.Cai Y, Anyatonwu G, Okuhara D, Lee KB, Yu Z, Onoe T, Mei CL, Qian Q, Geng L, Wiztgall R, Ehrlich BE, Somlo S. J Biol Chem. 2004 May 7; 2004 Jan 22. PMID: 14742446.
• A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel.Thrower EC, Choe CU, So SH, Jeon SH, Ehrlich BE, Yoo SH. J Biol Chem. 2003 Dec 12; 2003 Sep 23. PMID: 14506248.